[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"end-tidal-carbon-dioxide\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:end-tidal-carbon-dioxide":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,70],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100650171","tci-versus-manual-tiva-for-sedation-during-prone-kyphoplasty-effects-on-respiration-recovery-and-eeg-100650171",false,"NCT07745348","TCI Versus Manual TIVA for Sedation During Prone Kyphoplasty: Effects on Respiration, Recovery, and EEG","Investigation of the Effects of Target-Controlled Infusion (TCI) Anesthesia on Respiration, Recovery, and Electroencephalogram in Patients Undergoing Kyphoplasty in the Prone Position","Inclusion Criteria:\n\n\\- Age 18 years and older\n\n* ASA physical status classification I-III\n* Scheduled for kyphoplasty under sedation in the prone position\n* Provision of written informed consent\n\nExclusion Criteria:\n\n* Known allergy to any of the study medications\n\n  * ASA physical status classification IV or higher\n  * Patients deemed unsuitable for sedation (high pulmonary risk, morbid obesity, diagnosed severe obstructive sleep apnea)\n  * Refusal to participate or withdrawal of consent\n  * Diagnosis of dementia or Alzheimer's disease\n  * Communication difficulties precluding adequate assessment",true,"ALL","18 Years",{"count":20,"type":21},50,"ESTIMATED","OBSERVATIONAL","This single-center, prospective, observational study compares target-controlled infusion (TCI) versus manually administered total intravenous anesthesia (TIVA) for sedation in patients undergoing kyphoplasty in the prone position. The primary endpoints are the incidence of hypoxic episodes (SpO₂ \\\u003C 90%) and apneic attacks. Secondary endpoints include anesthesia quality scores, integrated pulmonary index (IPI) values, total propofol consumption, time to eye opening, time to full orientation, Modified Aldrete Scores and Richmond Agitation-Sedation Scale (RASS) scores in the recovery unit, and patient and surgeon satisfaction.",[25,26,27,28],"Kyphoplasty","Prone Position","Target Controlled Infusion of Propofol","End Tidal Carbon Dioxide",[30,31,32,33],"target controlled infusion","kyphoplasty","sedation","non-invasive etco2","NOT_YET_RECRUITING","2026-08-03",{"date":37,"type":38},"2026-08-04","ACTUAL",{"date":40,"type":21},"2026-07-10",{"date":42,"type":21},"2027-08-10",{"name":44,"class":45},"Marmara University Pendik Training and Research Hospital","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":57,"conditions":58,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":4},"100646345","comparison-of-i-gel-and-sacovlm-in-laparoscopic-cholecystectomy-100646345","NCT07692139","Comparison of I-gel and SaCoVLM in Laparoscopic Cholecystectomy","Comparison of Airway Performance Between I-gel and SaCoVLM in Patients Undergoing Elective Laparoscopic Cholecystectomy: A Prospective Observational Study","Inclusion Criteria:\n\n* Age between 18 and 70 years.\n* American Society of Anesthesiologists (ASA) physical status I-III.\n* Patients scheduled for elective laparoscopic cholecystectomy.\n* Patients undergoing general anesthesia.\n* Patients who provide written informed consent.\n\nExclusion Criteria:\n\n\\-","70 Years",{"count":56,"type":21},80,"This prospective observational study aims to compare the ventilation performance and safety of the i-gel and SaCoVLM supraglottic airway devices in adult patients undergoing elective laparoscopic cholecystectomy. Ventilation-related parameters, airway sealing performance, insertion characteristics, and perioperative complications will be evaluated.",[59,60,28],"Hemodynamic Monitoring","Laryngeal Mask Success Rate","2026-07-17",{"date":63,"type":38},"2026-07-21",{"date":65,"type":21},"2026-06-24",{"date":67,"type":21},"2026-12-31",{"name":69,"class":45},"Samsun University",{"id":71,"slug":72,"hasResults":11,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":78,"targetDuration":80,"studyType":22,"phases":4,"briefSummary":81,"conditions":82,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":99},"100631915","simplified-exercise-based-risk-assessment-in-lung-cancer-100631915","NCT07506889","Simplified Exercise-based Risk Assessment in Lung Cancer","EXercise-based Evaluation of Ventilatory Efficiency for enHanced Risk Assessment in Lungcancer trEatment Using End-tidal CO2: a Multicenter, Prospective Study","EXHALE-CO2","Inclusion Criteria:\n\n* Lung Cancer Diagnosis\n* Age of at least 18 years\n\nExclusion Criteria:\n\n* Not able to perform cycle ergometer exercise\n* Not able to understand spoken or written Swedish",{"count":79,"type":21},500,"1 Year","Physiological evaluation is part of the preoperative risk estimation in patients with lung cancer, and it aids in the choice of treatment. Ventilatory efficiency during exercise has emerged as a strong predictor of major postoperative complications, so far determined during a maximal cardiopulmonary exercise test. However, this test is limited by its availability and high cost, due to the requirement of high-technological equipment and advanced expertise. The current project aims to evaluate a simplified and accessible method for risk evaluation before decision on treatment in lung cancer. It builds on recent advances in technology and knowledge and combines a simple, low-intensity cycling test with measurement of ventilatory efficiency (end-tidal carbon dioxide pressure) with a handheld monitor. In a prospective, multi-center design the investigators will include patients evaluated for suspected lung cancer. The main objective is to establish threshold values for end-tidal carbon dioxide associated with low respectively high risk of major complications in patients undergoing surgery. In addition, the study aims to determine if end-tidal carbon dioxide can predict severe side-effects during neoadjuvant or curatively aiming systemic therapy. The project is closely linked to clinical practice, and the results can be easily implemented due to the simple and cost-efficient methodology. the suggested simplified approach would also allow access to physiological evaluation where more advanced methods are unavailable.",[83,84,85,86,87,88],"Lung Cancer (Diagnosis)","Lobectomy","Surgery Complications","Neoadjuvant Chemoimmunotherapy","End-Tidal Carbon Dioxide","Exercise","2026-04-02",{"date":91,"type":38},"2026-04-08",{"date":93,"type":21},"2026-04-01",{"date":95,"type":21},"2029-12",{"name":97,"class":98},"Linkoeping University","OTHER_GOV",5]