[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"estradiol\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:estradiol":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":5},"100648466","association-between-female-hormonal-profile-and-wound-healing-100648466",false,"NCT07724145","Association Between Female Hormonal Profile and Wound Healing","Association Between Female Hormonal Profile and Wound Healing Outcomes After Reduction Mammaplasty","FEMHEAL","Inclusion Criteria:\n\n* Symptomatic breast hypertrophy\n* Premenopausal\n\nExclusion Criteria:\n\n* Previous breast reduction surgery\n* Menopausal status\n* Oral contraceptives\n* Corticosteroid therapy\n* History of breast cancer\n* Active smoking and use of nicotine substitution products","FEMALE","18 Years",{"count":20,"type":21},84,"ESTIMATED","12 Months","OBSERVATIONAL","The goal of this observational study is to assess the relationship between female hormonal status and postoperative wound healing in reduction mammaplasty. The main questions it aims to answer are:\n\n1. Does wound healing differ depending on whether the operation takes place before or after ovulation in the menstrual cycle?\n2. Does estradiol have a positive effect on wound healing?\n\nParticipants with mammary hypertrophy will undergo reduction mammaplasty, and the investigators will measure their hormonal profile (LH, FSH, and estradiol) on the day of surgery.",[26,27,28],"Wound Healing","Wound Healing Complication","Estradiol",[30,31,32,33,34,35],"wound healing","menstrual cycle","estradiol","hormones","dehiscence","reduction mammaplasty","NOT_YET_RECRUITING","2026-07-21",{"date":39,"type":40},"2026-07-23","ACTUAL",{"date":42,"type":21},"2026-07",{"date":44,"type":21},"2028-12",{"name":46,"class":47},"University Hospital, Geneva","OTHER"]