[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"exercise-response\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:exercise-response":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":29,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100649037","diet-metabolic-health-and-exercise-responses-100649037",false,"NCT07728240","Diet, Metabolic Health, and Exercise Responses","Dietary Fat Quality, Metabolic Health, Cognitive Function, and Responses to Standardized Moderate-Intensity Exercise in Young Adults","Inclusion Criteria:\n\n* Age 18 years or older.\n* Able to provide written informed consent.\n* Able and willing to complete two laboratory visits, dietary recording, cognitive assessments, and exercise testing.\n* Able to safely complete submaximal exercise testing and a 30-minute moderate-intensity cycling session, as determined by health-history screening and the Physical Activity Readiness Questionnaire Plus (PAR-Q+).\n* Willing to complete dietary records and follow pre-visit instructions.\n\nExclusion Criteria:\n\n* Known cardiovascular, pulmonary, metabolic, neurological, psychiatric, or other medical condition that could make exercise testing or moderate-intensity exercise unsafe or substantially affect study outcomes.\n* Current pregnancy.\n* Current smoking.\n* Medication use that could substantially affect metabolic, cardiovascular, cognitive, or exercise-response outcomes, as determined by the investigators.\n\nOrthopedic injury, mobility limitation, or other physical condition that prevents safe cycling or exercise testing.\n\n* Resting heart rate greater than 100 beats per minute.\n* Resting blood pressure greater than 160\u002F100 mmHg.\n* Electrocardiogram abnormality requiring further medical evaluation.\n* Positive PAR-Q+ response or other health-screening finding indicating that medical clearance is required and has not been obtained.\n* Inability or unwillingness to complete study procedures, fasting requirements, dietary records, or pre-visit restrictions.\n* Any other condition that, in the judgment of the research team, would make participation unsafe or interfere with valid completion of the study procedures.","ALL","18 Years","60 Years",{"count":20,"type":21},100,"ESTIMATED","OBSERVATIONAL","Regular physical activity, healthy dietary habits, and good metabolic health are associated with numerous physical and cognitive health benefits. However, individuals vary substantially in their affective, motivational, and cognitive responses to exercise, and the factors contributing to this variability are not fully understood.\n\nThis prospective observational study will examine whether habitual dietary fat quality and metabolic health are associated with exercise responses, cognitive function, and academic-related outcomes in healthy young adults. Participants will complete assessments of dietary intake, body composition, metabolic health, aerobic fitness, cognitive function, and academic engagement. They will also complete a standardized moderate-intensity cycling session during which affective responses, exercise enjoyment, subjective energy, and motivation for future physical activity will be assessed.\n\nThe findings will improve understanding of how habitual dietary habits and metabolic health may influence responses to exercise and cognitive functioning and may help inform future lifestyle recommendations aimed at promoting physical activity participation, cognitive performance, and overall health.",[25,26,27,28],"Diet Quality","Metabolic Health","Cognitive Function","Exercise Response",[30,31,32,33,34,35],"Dietary fat quality","Metabolic health","Exercise affect","Exercise motivation","Cognitive function","Exercise enjoyment","RECRUITING","2026-07-21",{"date":39,"type":40},"2026-07-27","ACTUAL",{"date":42,"type":21},"2026-08-01",{"date":44,"type":21},"2027-07-31",{"name":46,"class":47},"University of Wisconsin, River Falls","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":4,"studyType":62,"phases":63,"briefSummary":65,"conditions":66,"keywords":67,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":4},"100570243","caffeine-mouth-rinse-on-salivary-immunoglobulin-a-lactoferrin-and-a-amylase-levels-100570243","NCT06704711","Caffeine Mouth Rinse on Salivary Immunoglobulin A, Lactoferrin and A-Amylase Levels","The Effect of Incremental Exercise After Caffeine Mouth Rinse on Salivary Immunoglobulin A, Lactoferrin and A-Amylase Levels","Inclusion Criteria:\n\n* Healthy men who have not had any previous injuries, do not have a chronic disease, do not use medication, do not smoke, and have played or are playing football as an amateur.\n\nExclusion Criteria:\n\nThose who have had any previous injury, have a chronic disease, use medication, or smoke.\n\n\\-",true,"MALE","19 Years","26 Years",{"count":61,"type":21},30,"INTERVENTIONAL",[64],"NA","The goal of this clinical trial is to investigate the effects of the mouth rinse form of caffeine (400 mg) on salivary lactoferrin, α-amylase and secretory immunoglobulin-a levels after incremental exercise in young amateur football players. The main questions it aims to answer are:\n\n* Caffeine in mouth rinse form increases salivary immunoglobulin a after incremental exercise\n* Caffeine in mouth rinse form increases salivary lactoferrin after incremental exercise\n* Caffeine in mouth rinse form increases salivary a-amylase after incremental exercise.\n\nThis 3-session study will use a double-blind, randomized, placebo-controlled crossover experimental design. participants will complete three different treatments \\[caffeine (CAF), control (C) and placebo (PLA)\\] separated by at least 1 week. Baseline saliva samples will be collected while sitting in a chair and then:\n\n* CAF Group: They will rinse a solution containing a total of 400 mg caffeine (20 mL, 2% concentration) in the mouth for 20 seconds and try to continue the exercise against increasing resistance until exhaustion.\n* Control Group: Only rinse a solution containing a total of 400 caffeine (20 mL, 2% concentration) in the mouth for 20 seconds and receive no exercise treatment.\n* Placebo Group: They will rinse 20 mL of distilled water in the mouth for 20 s and try to continue the exercise against increasing resistance until exhaustion.\n\nSaliva samples will be collected at 6 different time points: 5 minutes before exercise (or caffeine mouth rinse) (T0-reference), immediately after caffeine mouth rinse (or immediately before exercise) (T1), 5 minutes\u002Fmidway through exercise (T2), and immediately after exercise (T3), 60 minutes after the end of exercise (T4) and 120 minutes after the end of exercise (T5).All data will be statistically analyzed using SPSS 25.0 software (Chicago, IL, USA) and expressed as mean ± standard deviation. Shapiro-Wilk and Levene tests will be used to determine whether the data are normally distributed and whether the variance is homogeneous. Repeated measures ANOVA test will be used to compare group means. If there is a difference between the groups as a result of the analysis, post-hoc tests will be used to find out from which group this difference originates. In cases where the data are not normally distributed, nonparametric test methods will be used. The significance level of the tests will be accepted as p\\\u003C0.05",[28],[68,69,70,71,72],"Sportomics","Salivary immunuglobulin-a","salivary lactoferrin","salivary a-amylase","caffeine","NOT_YET_RECRUITING","2024-11-21",{"date":76,"type":40},"2024-11-26",{"date":78,"type":21},"2024-11-15",{"date":80,"type":21},"2024-12-30",{"name":82,"class":47},"University of Gaziantep"]