[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"family-caregivers\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:family-caregivers":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,15,0,[8,40,69,101,127,155,182,211,240,267,296,317,360,384,408],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":4},"100652444","phase-2-legacy-photo-narrative-study-100652444",false,"NCT07774663","Legacy Photo-narrative Study","Photo-narratives as a Legacy Intervention for Children With Medical Complexity and Their Families","Inclusion Criteria:\n\n* has a child who receives care at one of the study sites for a complex medical condition and is followed by the complex care and\u002For palliative care team\n* has a child who is ages 3 months through 25 years old\n* has a child who has previously been home\u002Fdischarged\n* has a child whose life expectancy of \\>6 months\n\nExclusion Criteria:\n\n* are not the child's identified parent\u002Flegally authorized representative\n* has a preferred language of care other than English or Spanish\n* has an active psychiatric or chronic health concerns that preclude research participation\n* has active child protective services involvement","ALL","3 Months",{"count":19,"type":20},40,"ESTIMATED","INTERVENTIONAL",[23],"PHASE2","Children with medical complexity (CMC) live full meaningful lives that are often short. CMC and their families experience substantial distress, poor mental health, and low emotional well-being. Existing research and our prior studies suggest that legacy, defined as the summation of qualities and experiences that form the child's enduring presence, can be a resource for actionable appraisal of and coping with stressful life experiences. Photo-narratives are a novel intervention that facilitate family sharing of images to tell stories about everyday experiences related to their child's quality-of-life and personhood. In our prior studies, families reported that photo-narratives were a simple, easy way to meaningfully connect and had the potential to be an important part of their child's legacy. What remains poorly understood, however, is how photo-narratives might impact family-centered outcomes. This study aims to and evaluate the feasibility, acceptability, and potential impact of photo-narratives in a pilot randomized controlled trial.",[26,27],"Children With Medical Complexity (CMC)","Family Caregivers","NOT_YET_RECRUITING","2026-08-17",{"date":31,"type":32},"2026-08-19","ACTUAL",{"date":34,"type":20},"2027-06-01",{"date":36,"type":20},"2028-06-15",{"name":38,"class":39},"Seattle Children's Hospital","OTHER",{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":48,"sex":16,"minAge":49,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":21,"phases":52,"briefSummary":54,"conditions":55,"keywords":58,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":68},"100651769","communication-and-hospice-online-with-optimal-support-and-engagement-100651769","NCT07764432","Communication and Hospice Online With Optimal Support and Engagement","Communication and Hospice Online With Optimal Support and Engagement (CHOOSE)","CHOOSE","Eligibility Criteria:\n\n* Family caregiver of cancer patient receiving hospice care from an affiliated hospice organization. Only 1 FCG per patient may be enrolled.\n* At least 18 years of age.\n* Can speak and understand English.\n* Able to access the internet.\n* Has a Facebook account or is willing to create a Facebook account in order to be in this study",true,"18 Years",{"count":51,"type":20},567,[53],"NA","The project is a multisite, three-group randomized control trial (RCT) with equal and parallel mixed-methods analysis that allows standardized measures combined with rich qualitative data to test hypotheses and answer research questions. Family caregivers (FCGs) of hospice cancer patients will be recruited and randomized into one of three groups: usual hospice care only (UC), usual care online support group (UCOSG) (without communication strategies), and the CHOOSE intervention group (with communication focus).",[56,27,57],"Caregivers","Cancer Caregivers",[56,27,57],"2026-08-06",{"date":61,"type":32},"2026-08-14",{"date":63,"type":20},"2027-02-01",{"date":65,"type":20},"2031-04-30",{"name":67,"class":39},"Washington University School of Medicine",1,{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":4,"eligibilityCriteria":75,"healthyVolunteers":11,"sex":16,"minAge":49,"maxAge":4,"enrollmentInfo":76,"targetDuration":4,"studyType":21,"phases":78,"briefSummary":79,"conditions":80,"keywords":83,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":68},"100651534","the-familystrong-pilot-randomized-trial-100651534","NCT07761988","The FamilyStrong Pilot Randomized Trial","Brief Distress Support for Family Caregivers of Persons With Advanced Cancer: The FamilyStrong Pilot Randomized Trial","Inclusion Criteria:\n\n* CAREGIVERS:\n\n  1\\) ≥18 years of age; 2) self-endorsing or identified by the patient as \"a relative, friend, or partner that has a close relationship with you and who assists with your health and medical care and who may or may not live in the same residence as you and who is not paid for their help\"; 3) caring for a patient with advanced-stage cancer (see definition under Patient Inclusion criteria below) who is not enrolled in hospice; 4) caregivers will NOT need to have a patient willing to participate; and 5) able to speak and read English and complete baseline measures.\n* PATIENTS:\n\n  1. ≥18 years of age; 2) screened within 60 days of an oncology visit where the patient had documentation of a new diagnosis of an advanced stage cancer, defined as metastatic and\u002For recurrent\u002Fprogressive stage III\u002FIV cancer, including brain, lung, breast, gynecologic, head and neck, gastrointestinal, genitourinary cancer, melanoma; and hematologic malignancies; and 3) able to speak and read English and complete baseline measures.\n\nExclusion Criteria:\n\n* CAREGIVERS:\n\n  1\\) Self-reported active, untreated mental illness (i.e., schizophrenia, bipolar disorder, or major depressive disorder), dementia, active suicidal ideation, uncorrected hearing loss, or active substance abuse.\n* PATIENTS:\n\n  1. Receiving hospice per EHR; 2) Per EHR, active, untreated mental illness (i.e., schizophrenia, bipolar disorder, or major depressive disorder), dementia, suicidal ideation, uncorrected hearing loss, or substance abuse.",{"count":77,"type":20},120,[53],"When someone is diagnosed with advanced cancer, their family members and close friends often take on the role of caregiver, providing emotional support and complex medical care for their loved one, often for up to eight hours a day. This responsibility can take a significant toll, leaving family caregivers overwhelmed, highly stressed, and without access to the support they need. Research shows that when caregivers are struggling, both they and the patients they care for suffer. Caregiver distress has been linked to poor quality of life for patients and greater emotional strain on families. Despite the well-documented emotional and physical burdens on family caregivers, most cancer centers do not include structured support services to help them cope and navigate challenges. Many caregivers do not even realize help is available, leading to feelings of isolation and burnout. Yet, despite the critical role caregivers play in cancer care, there are very few programs designed to support them in ways that are both effective and widely accessible. To address this urgent need, our team has developed FamilyStrong, a novel intervention specifically designed to fill this gap and support family caregivers in real-world cancer care settings. FamilyStrong is a brief and easy-to-use program that helps family caregivers recognize and manage distress while connecting them to the right support. Unlike many caregiver support programs that require extensive time and highly trained specialists, FamilyStrong is led by lay navigators, who are trained individuals who can guide caregivers through challenges and connect them with appropriate resources. The program uses a simple distress screening tool to quickly assess how caregivers are coping and then tailors support to their specific needs. We will test FamilyStrong in a small pilot study with 60 caregivers of patients newly diagnosed with advanced cancer. Over a period of 24 weeks, we will evaluate how well the program works, whether caregivers find it helpful, and whether it improves caregiver and patient well-being compared to usual care. Specifically, we will measure whether caregivers experience lower stress, improved quality of life, and fewer unmet needs when they participate in the FamilyStrong program. After this study, we will use these results and our experiences to inform a larger clinical trial to confirm FamilyStrong's benefits and eventually expand the program nationwide. By providing caregivers with practical, effective support, FamilyStrong has the potential to improve the quality of life for both caregivers and cancer patients, ensuring that families facing cancer receive the help they need when they need it most.",[27,81,82],"Distress in Caregivers of Cancer Patients","Advanced Cancer",[84,85,86,87,88,89,90,91,92],"family caregiver","cancer caregiving","caregiver support","distress screening","lay navigation","supportive care","psychosocial support","telehealth","unmet supportive care needs",{"date":94,"type":32},"2026-08-13",{"date":96,"type":20},"2027-01-01",{"date":98,"type":20},"2028-09-30",{"name":100,"class":39},"University of Alabama at Birmingham",{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":105,"acronym":4,"eligibilityCriteria":106,"healthyVolunteers":11,"sex":16,"minAge":49,"maxAge":4,"enrollmentInfo":107,"targetDuration":4,"studyType":21,"phases":109,"briefSummary":110,"conditions":111,"keywords":115,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":118,"lastUpdatePostDateStruct":119,"startDateStruct":121,"completionDateStruct":123,"leadSponsor":125,"locationsCount":68},"100649187","adapting-a-psychosocial-support-intervention-for-the-rett-syndrome-community-100649187","NCT07730112","Adapting a Psychosocial Support Intervention for the Rett Syndrome Community","Inclusion Criteria:\n\n* Adult caregiver (≥18 years old) of an individual with Rett syndrome Caregiver of a child or individual of any age with a confirmed clinical diagnosis of Rett syndrome.\n* English-speaking and able to read and understand study materials Willing and able to participate in a 6-week, online psychosocial intervention delivered via a private social media platform\n* Willing and able to complete electronic surveys and, if selected, participate in virtual interviews\n* For randomized phase participation: child is receiving standard pharmacologic treatment for Rett syndrome (e.g., Daybue) as part of routine clinical care\n\nExclusion Criteria:\n\n* Inability to speak, read, or understand English sufficiently to participate in the intervention and assessments.\n* Caregiver under the age of 18 years\n* Lack of confirmed diagnosis of Rett syndrome in the care recipient.\n* Inability or unwillingness to provide informed consent.\n* Lack of access to required technology (internet-enabled device and ability to access the online intervention platform).",{"count":108,"type":20},60,[53],"This study seeks to adapt Caregiver Speaks, a psychosocial supportive intervention delivered through Facebook, for parent caregivers of children living with Rett Syndrome. This study also seeks to explore feasibility and acceptability of implementing the adapted intervention, and its impact on parent psychological outcomes.",[112,27,113,114],"Rett Syndrome","Social Support","Psychological Support",[27,112,116,117],"Online Support Group","Meaning-making","2026-07-22",{"date":120,"type":32},"2026-07-28",{"date":122,"type":20},"2026-08-01",{"date":124,"type":20},"2028-05-31",{"name":126,"class":39},"Colorado State University",{"id":128,"slug":129,"hasResults":11,"nctId":130,"briefTitle":131,"officialTitle":131,"acronym":4,"eligibilityCriteria":132,"healthyVolunteers":11,"sex":16,"minAge":49,"maxAge":4,"enrollmentInfo":133,"targetDuration":4,"studyType":21,"phases":135,"briefSummary":136,"conditions":137,"keywords":142,"overallStatus":144,"whyStopped":4,"lastUpdateSubmitDate":145,"lastUpdatePostDateStruct":146,"startDateStruct":148,"completionDateStruct":150,"leadSponsor":152,"locationsCount":68},"100628577","effectiveness-of-chatbot-for-improving-caregiving-outcomes-in-primary-caregivers-of-geriatric-pneumonia-patients-a-study-on-knowledge-attitude-and-practice-100628577","NCT07463443","Effectiveness of Chatbot for Improving Caregiving Outcomes in Primary Caregivers of Geriatric Pneumonia Patients: A Study on Knowledge, Attitude and Practice.","Inclusion Criteria:\n\n* (1)Patients with a primary diagnosis of pneumonia during the current hospitalization.(2)Patients aged 65 years or older.(3)Primary caregivers aged 18 years or older.(4)Primary caregivers who can read and understand Mandarin Chinese.(5)Primary caregivers who own a mobile device (e.g., smartphone or tablet) and can use the chatbot application.\n\nExclusion Criteria:\n\n* (1)Primary caregivers who do not live with the patient.(2)Primary caregivers who have received formal training as professional nursing assistants or caregivers.(3)Primary caregivers who are currently or were formerly healthcare professionals (e.g., physicians, nurses, therapists).(4)Primary caregivers who do not possess a mobile device or are unable to use chatbot applications.",{"count":134,"type":20},150,[53],"Pneumonia is a leading cause of death and hospitalization among the elderly in Taiwan. High-quality home care is essential to recovery and reducing readmission, yet primary caregivers often lack the specific skills needed, such as airway clearance and safe feeding techniques. Traditional education, consisting of one-time verbal instructions and paper brochures, often lacks interactivity and real-time support.\n\nThis study introduces \"Pneumonia Care Helper,\" an interactive LINE chatbot designed to provide digital health education. The goal is to evaluate whether this digital tool is more effective than traditional paper-based education in improving the knowledge, attitudes, and caregiving practices of primary caregivers of elderly pneumonia patients. The study will compare the outcomes of caregivers using the chatbot versus those receiving standard paper-based instructions over a 5-day intervention period.",[138,27,139,140,141],"Pneumonia","Knowledge, Attitudes, Practice","Chatbot","Geriatric Patient",[138,27,139,140,143],"Geriatric patient","RECRUITING","2026-07-13",{"date":147,"type":32},"2026-07-15",{"date":149,"type":32},"2026-03-13",{"date":151,"type":20},"2027-02-24",{"name":153,"class":154},"Taipei Veterans General Hospital, Taiwan","OTHER_GOV",{"id":156,"slug":157,"hasResults":11,"nctId":158,"briefTitle":159,"officialTitle":160,"acronym":161,"eligibilityCriteria":162,"healthyVolunteers":48,"sex":16,"minAge":163,"maxAge":164,"enrollmentInfo":165,"targetDuration":4,"studyType":21,"phases":167,"briefSummary":168,"conditions":169,"keywords":4,"overallStatus":144,"whyStopped":4,"lastUpdateSubmitDate":173,"lastUpdatePostDateStruct":174,"startDateStruct":176,"completionDateStruct":178,"leadSponsor":180,"locationsCount":68},"100645236","financial-counseling-for-dementia-family-caregivers-in-early-and-middle-adulthood-100645236","NCT07681401","Financial Counseling for Dementia Family Caregivers in Early and Middle Adulthood","Financial Counseling and Advocacy for Alzheimer's Disease and Related Dementias Family Caregivers in Early and Middle Adulthood","FCA 4 FC-EAMA","Inclusion Criteria:\n\n* Caring for a family member, neighbor, or friend with ADRD\n* Providing care for 20 or more hours per week,\n* Technology access for Zoom visits\n* English speaking\n\nExclusion Criteria:\n\n* N\u002FA","25 Years","55 Years",{"count":166,"type":20},10,[53],"The goal of this National Institutes of Health (NIH) Stage 1a study is to develop and pilot test a research- and community-informed financial counseling and advocacy (FCA) intervention for dementia family caregivers in early and middle adulthood. The main question it aims to answer is:\n\nIs a research- and community-informed financial counseling and advocacy intervention usable, feasible and acceptable for dementia family caregivers in early and middle adulthood?\n\nParticipants will engage in a four-week single group financial counseling and advocacy intervention and complete pre- and post-intervention measures addressing financial well-being, caregiver strain, workplace productivity, and flourishing along with usability, acceptability, and feasibility measures.",[27,170,171,172],"Dementia","Financial Wellbeing","Financial Coaching","2026-06-25",{"date":175,"type":32},"2026-07-02",{"date":177,"type":32},"2026-04-10",{"date":179,"type":20},"2026-10",{"name":181,"class":39},"University of Utah",{"id":183,"slug":184,"hasResults":11,"nctId":185,"briefTitle":186,"officialTitle":187,"acronym":4,"eligibilityCriteria":188,"healthyVolunteers":11,"sex":16,"minAge":189,"maxAge":4,"enrollmentInfo":190,"targetDuration":4,"studyType":21,"phases":192,"briefSummary":193,"conditions":194,"keywords":198,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":203,"lastUpdatePostDateStruct":204,"startDateStruct":206,"completionDateStruct":207,"leadSponsor":209,"locationsCount":68},"100642304","intervention-to-reduce-unwanted-loneliness-in-family-caregivers-of-people-with-alzheimer-100642304","NCT07639645","Intervention to Reduce Unwanted Loneliness in Family Caregivers of People With Alzheimer","Multimodal Intervention to Reduce Unwanted Loneliness and Improve the Living With Process Among Family Caregivers of People With Alzheimer's Disease","Inclusion Criteria:\n\n* Family caregivers of people with Alzheimer's disease (AD).\n* Primary family caregivers who live with the person with AD.\n* The person with AD must be enrolled in one of the adult day care centers where the study is conducted.\n* Ability to communicate in Spanish and\u002For Valencian.\n\nExclusion Criteria:\n\n* Presence of moderate or severe cognitive impairment, mental disorder, significant sensory impairment, disabling chronic illness, or any medical condition that contraindicates participation in any of the study activities.\n* Family caregivers of institutionalized individuals.\n* Family caregivers of people with AD who have died.","65 Years",{"count":191,"type":20},50,[53],"The absence of social relationships negatively affects physical, psychological, and social health. In other words, it alters people's quality of life and makes active aging difficult. The investigators have designed a study to reduce unwanted loneliness and improve the living with process of family caregivers of people with Alzheimer disease through multiple interventions (music therapy, health education)",[195,196,27,197],"Alzheimer Disease (AD)","Unwanted Loneliness","Living With Process",[199,200,201,84,202],"unwanted loneliness","living with process","alzheimer disease","multicomponent intervention","2026-06-10",{"date":205,"type":32},"2026-06-15",{"date":179,"type":20},{"date":208,"type":20},"2028-12",{"name":210,"class":39},"University of Valencia",{"id":212,"slug":213,"hasResults":11,"nctId":214,"briefTitle":215,"officialTitle":216,"acronym":217,"eligibilityCriteria":218,"healthyVolunteers":48,"sex":16,"minAge":49,"maxAge":4,"enrollmentInfo":219,"targetDuration":4,"studyType":21,"phases":221,"briefSummary":222,"conditions":223,"keywords":227,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":231,"lastUpdatePostDateStruct":232,"startDateStruct":234,"completionDateStruct":236,"leadSponsor":238,"locationsCount":68},"100640320","tiva-mobile-health-intervention-for-family-caregivers-100640320","NCT07616284","TIVA Mobile Health Intervention for Family Caregivers","A Mobile Health Intervention for the Promotion of Mental Health in Family Caregivers: Protocol for a Pilot Study","TIVA-Pilot","Inclusion Criteria:\n\n* Adults aged 18 years or older.\n* Unpaid family caregivers of a person with chronic illness, disability, or dependency.\n* Providing regular caregiving assistance for at least 4 months.\n* Living in Portugal.\n* Ability to read and understand Portuguese.\n* Ownership and use of a smartphone with internet access compatible with the TIVA mobile application.\n* Willingness to install and use the TIVA app for 4 weeks.\n* Ability to provide informed consent.\n\nExclusion Criteria:\n\n* Severe cognitive impairment.\n* difficulties preventing independent use of the application or completion of study assessments.\n* Severe psychiatric disorder or acute mental health crisis interfering with participation.\n* Participation in another structured caregiver support or psychological intervention during the study period.\n* Inability to use a smartphone independently.",{"count":220,"type":20},80,[53],"This pilot study aims to evaluate the feasibility, usability, and preliminary effects of the TIVA mobile health intervention in promoting positive mental health among family caregivers of older adults. TIVA is a culturally adapted mobile application based on Lluch's Positive Mental Health model and designed to support caregivers through daily activities, motivational messages, relaxation strategies, and psychoeducational content over a four-week intervention period.\n\nA pilot randomized controlled study with parallel allocation will be conducted involving family caregivers recruited in community and primary healthcare settings in Portugal. Participants will be allocated either to the TIVA intervention group or to a usual care control group. Outcomes will include positive mental health, caregiver burden, usability, satisfaction, adherence, and acceptability. Data will be collected at baseline, post-intervention, and follow-up.\n\nThis study intends to contribute to the development of accessible digital mental health strategies to support family caregivers and promote healthy ageing.",[224,27,225,226],"Positive Mental Health","Mental Health Promotion","Caregiver Burden",[228,27,224,229,225,230,226],"TIVA mHealth","Older Adults","Mobile Application","2026-05-29",{"date":233,"type":32},"2026-06-01",{"date":235,"type":20},"2026-09",{"date":237,"type":20},"2027-04",{"name":239,"class":39},"Universidade do Porto",{"id":241,"slug":242,"hasResults":11,"nctId":243,"briefTitle":244,"officialTitle":245,"acronym":246,"eligibilityCriteria":247,"healthyVolunteers":11,"sex":16,"minAge":49,"maxAge":4,"enrollmentInfo":248,"targetDuration":4,"studyType":21,"phases":250,"briefSummary":251,"conditions":252,"keywords":256,"overallStatus":144,"whyStopped":4,"lastUpdateSubmitDate":258,"lastUpdatePostDateStruct":259,"startDateStruct":261,"completionDateStruct":263,"leadSponsor":265,"locationsCount":68},"100610253","mhealth-for-early-psychosis-caregivers-in-statewide-program-outreach-100610253","NCT07225179","mHealth for Early Psychosis Caregivers in Statewide Program Outreach","Bolster-NC: A Pilot Study of the Bolster mHealth Intervention Within Early Psychosis Program Outreach in North Carolina","Bolster-NC","Inclusion Criteria:\n\n* 18 years or older\n* North Carolina resident\n* Caregiver to a young adult with early psychosis, wherein early psychosis is defined as: (1) Being between the ages of 15 and 30, and (2) Within the past five years, the young adult first experienced hallmark symptoms: (2A) Presence of psychotic symptoms represented by one or more of hallucinations, delusions, marked thought disorder, psychomotor disorder or bizarre behavior, as well as (2B) Definite change of personality or behavior manifesting as two or more of the following: serious deterioration of function, marked social withdrawal, persistent self-neglect, episodic marked anxiety.\n* A positive screen according to the Caregiver Prime Screen - Revised (endorsed two or more responses of five or six (\"somewhat\"\u002F\"definitely\" agree)\n* Own an Apple iPhone\n* Have access to the internet (e.g., via WiFi or data plan)\n* Self-identify as a caregiver of the affected person\n* Are proficient in English to the degree necessary to complete study assessments and engage meaningfully in the intervention\n\nExclusion Criteria:\n\n* Participant failed to demonstrate understanding of study details in comprehension screening process.\n* Previous enrollment in a study involving Bolster.\n* Activity on screening questionnaires that indicates suspicious or dishonest participation such that the participant is likely to be a \"malicious actor\" or \"gamer\" (i.e. an individual that attempts to enroll in online research studies solely for compensation with dishonest or illegitimate responses to study questionnaires)",{"count":249,"type":20},30,[53],"The purpose of this study is to pilot the delivery of an mHealth intervention for caregivers to young people with early psychosis within a network of early psychosis intervention programs in the state of North Carolina. The investigators will examine the feasibility of recruitment through program outreach, develop North Carolina specific outreach resources to be used with the mHealth intervention and evaluate the effectiveness of this intervention for reducing caregiver psychological morbidity and improving family communication. The investigators will also collect pilot data to inform recruitment and development of implementation strategies for delivering Bolster within a statewide early psychosis network.",[253,254,255,27],"Caregiver","Caregiver Distress","Caregiver to a Young Adult With Early Psychosis",[253,257],"Caregiver Support","2026-05-26",{"date":260,"type":32},"2026-05-27",{"date":262,"type":32},"2025-12-01",{"date":264,"type":20},"2027-07-30",{"name":266,"class":39},"University of North Carolina, Chapel Hill",{"id":268,"slug":269,"hasResults":11,"nctId":270,"briefTitle":271,"officialTitle":272,"acronym":4,"eligibilityCriteria":273,"healthyVolunteers":48,"sex":16,"minAge":274,"maxAge":4,"enrollmentInfo":275,"targetDuration":4,"studyType":21,"phases":277,"briefSummary":278,"conditions":279,"keywords":284,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":288,"lastUpdatePostDateStruct":289,"startDateStruct":291,"completionDateStruct":293,"leadSponsor":294,"locationsCount":68},"100624817","effectiveness-of-an-web-application-in-enhancing-informal-caregivers-nasogastric-tube-feeding-competency-100624817","NCT07414563","Effectiveness of an Web Application in Enhancing Informal Caregivers' Nasogastric Tube Feeding Competency","Effectiveness of an Nasogastric Web Application in Reducing Time to Achieve Nasogastric Tube Feeding Competency Among Informal Caregivers","Caregivers who will receive standard face-to-face training\n\nInclusion Criteria:\n\n* Individual who has been identified by the healthcare team to undergo caregiver training for nasogastric feeding to assist a patient with nutritional needs.\n* No prior training or experience in nasogastric feeding.\n* Potentially able to complete course of caregiver training for nasogastric feeding in the hospital of enrolment.\n* Aged 21 and above.\n\nExclusion Criteria:\n\n* Caregivers who are cognitively impaired.\n* Have received prior training for nasogastric feeding.\n* Will not be able to complete their course of caregiving training for nasogastric feeding in the hospital of enrolment.\n\nCaregivers who will receive standard face-to-face training plus access to the web application\n\nInclusion Criteria:\n\n* Individual who has been identified by the healthcare team to undergo caregiver training for nasogastric feeding to assist a patient with nutritional needs.\n* No prior training or experience in nasogastric feeding.\n* Potentially able to complete course of caregiver training for nasogastric feeding in the hospital of enrolment.\n* Have the basic literacy skills to use the nasogastric tube web application.\n* Able to access and use the nasogastric web application over the course of their training in nasogastric tube feeding to support their learning.\n* Aged 21 and above.\n\nExclusion Criteria:\n\n* Caregivers who are cognitively impaired.\n* Have received prior training for nasogastric feeding.\n* Will not be able to complete their course of caregiving training for nasogastric feeding in the hospital of enrolment.\n* Have no or limited literacy ability to use the nasogastric web application\n* Unable to access and use the nasogastric web application over the course of their training in nasogastric tube feeding.\n\nPatients\n\nInclusion Criteria:\n\n* Aged 50 years and above.\n* Patient whose caregiver has been identified to undergo nasogastric tube feeding training to support their nutritional needs.\n* Has mental capacity as per the approved documentation of capacity form or has a legal representative willing to provide consent to allow study team to extract medical records.","21 Years",{"count":276,"type":20},136,[53],"The goal of this trial is to determine whether adding a nasogastric tube web application to standard face-to-face caregiver training helps informal caregivers learn nasogastric tube feeding more quickly than standard training alone.\n\nThe main question is:\n\nDoes the use of a nasogastric tube web application alongside standard face-to-face caregiver training shorten the time required for caregivers to learn nasogastric tube feeding, compared with standard training alone?\n\nResearchers will compare two groups: caregivers who receive standard face-to-face training plus access to the web application and caregivers who only receive standard face-to-face training to see who will learn nasogastric tube feeding more quickly.\n\nParticipants will:\n\n* Receive either standard face-to-face training plus the web application or standard face-to-face training alone when identified for nasogastric tube feeding training.\n* Have their time taken to learn nasogastric tube feeding recorded.",[280,281,27,282,283],"Nasogastric Feeding","Training Family Caregivers","Informal Caregiver","Dysphagia",[285,286,27,287],"Nasogastric Tube Feeding","Caregiver Training","Web Application","2026-02-10",{"date":290,"type":32},"2026-02-17",{"date":292,"type":20},"2026-03",{"date":235,"type":20},{"name":295,"class":39},"Tan Tock Seng Hospital",{"id":297,"slug":298,"hasResults":11,"nctId":299,"briefTitle":300,"officialTitle":301,"acronym":4,"eligibilityCriteria":302,"healthyVolunteers":11,"sex":16,"minAge":49,"maxAge":4,"enrollmentInfo":303,"targetDuration":4,"studyType":21,"phases":304,"briefSummary":305,"conditions":306,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":308,"lastUpdatePostDateStruct":309,"startDateStruct":311,"completionDateStruct":313,"leadSponsor":315,"locationsCount":68},"100621235","a-feasibility-study-of-death-education-intervention-for-family-caregivers-of-advanced-cancer-patients-100621235","NCT07367984","A Feasibility Study of Death Education Intervention for Family Caregivers of Advanced Cancer Patients","Death Education Intervention for Family Caregivers of Advanced Cancer Patients: a Mixed-methods Feasibility Study","Inclusion Criteria for patients:\n\n* Age 18 years or older;\n* The patient with pathologically confirmed stage III or IV cancer;\n* The patient has initiated any systemic anti-cancer therapy (e.g.,chemotherapy, immunotherapy, targeted therapy, endocrine therapy) and has completed the first treatment administration\u002Fcycle and commenced the next planned administration\u002Fcycle;\n* The patient is assessed by the doctor as having an estimated life expectancy of ≥3 months; and\n* The patient is aware of their advanced cancer diagnosis.\n\nExclusion Criteria for patients:\n\n-The patient has no primary family caregiver during the study period.\n\nInclusion Criteria for family caregivers:\n\n* Age 18 years or older;\n* The caregiver is identified by the patient as the primary family caregiver (e.g., spouse, adult child, parent, or other relative);\n* The caregiver has been regularly involved in caregiving for the patient in the past month, and is expected to continue providing support over the next two months (e.g., daily care, accompaniment, involvement in medical communication\u002Fdecision-making, and financial support);\n* Since taking on the primary caregiving role, the caregiver reports the frequency of talking about death\u002Fdying with the patient as \"Never\" or \"Rarely\" (from: Never \u002F Rarely \u002F Sometimes \u002F Often \u002F Very often);\n* The caregiver perceives a need for guidance and support in communicating with the patient about death-related matters; and\n* The caregiver has basic Chinese literacy (reading and writing) to understand the intervention content and complete written tasks.\n\nExclusion Criteria for family caregivers:\n\n* Paid or professional caregivers who receive financial compensation for providing caregiving services;\n* The caregiver provides financial support only, without regular contact with the patient;\n* The caregiver has significant cognitive impairment that would affect understanding the intervention and completing the study;\n* The caregiver has severe psychiatric symptoms that would affect understanding the intervention and completing the study;\n* The caregiver has significant communication difficulties that would affect understanding the intervention and completing the study;\n* The caregiver is unable to complete the 4-week intervention due to physical limitations (e.g., mobility restrictions preventing attendance at intervention sessions);\n* The caregiver has practical constraints that would prevent completion of the 4-week intervention or follow-up assessments (e.g., expected prolonged travel during the intervention period or inability to complete assessments as scheduled); and\n* The caregiver is currently receiving other structured psychological intervention or psychotherapy that is likely to affect study outcomes.",{"count":249,"type":20},[53],"Advanced cancer is the leading cause of death in the world and China. Family caregivers, as the closest individuals to advanced cancer patients, suffer from a range of psychological and spiritual issues due to patients' impending death. Various types of death education interventions have been developed to assist individuals in understanding the meaning of life and death and adapting to dying to address psychological and spiritual issues. However, these interventions have predominantly focused on advanced cancer patients only, with a significant gap in support for family caregivers.\n\nA mixed methods feasibility study will be conducted. A convenience sample of at least 30 family caregivers will be recruited. Participants will receive four 60-minute sessions, flexibly scheduled within a four-week period according to each participant's conditions. The researcher will be trained to deliver the intervention through individual face-to-face sessions in the oncology ward meeting room of the same hospital in phase I. The primary outcome will be feasibility (time to complete the recruitment, eligibility rate, recruitment rate, retention rate, attendance rate, acceptability rate). Secondary outcomes will be measured for preliminary intervention effectiveness on family caregivers' communication with patients on death, anxiety, depression, spiritual well-being, attitudes towards death, and quality of life after collecting the demographic information and written consent forms, and post-intervention. A descriptive qualitative evaluation will be conducted with 12 family caregivers to explore their experience of participating in the intervention by another researcher. The qualitative data in phase II will be audio-taped and transcribed verbatim and analysed using NVivo 14 through thematic analysis. The quantitative data will be entered in SPSS version 29.0. Descriptive statistics will be used to summarise the profiles of participants and outcomes.",[307,82,27],"Palliative Care","2026-01-20",{"date":310,"type":32},"2026-01-26",{"date":312,"type":20},"2026-03-01",{"date":314,"type":20},"2026-08-31",{"name":316,"class":39},"The Hong Kong Polytechnic University",{"id":318,"slug":319,"hasResults":11,"nctId":320,"briefTitle":321,"officialTitle":322,"acronym":4,"eligibilityCriteria":323,"healthyVolunteers":48,"sex":16,"minAge":49,"maxAge":4,"enrollmentInfo":324,"targetDuration":4,"studyType":326,"phases":4,"briefSummary":327,"conditions":328,"keywords":334,"overallStatus":144,"whyStopped":4,"lastUpdateSubmitDate":352,"lastUpdatePostDateStruct":353,"startDateStruct":355,"completionDateStruct":356,"leadSponsor":358,"locationsCount":68},"100613698","msci-mobile-health-app-for-veterans-with-sci-and-caregivers-100613698","NCT07269977","mSCI: Mobile Health App for Veterans With SCI and Caregivers","mSCI: mHealth for Supporting Psychosocial Health of Military Service Members With SCI and Their Family Caregivers","Inclusion Criteria:\n\n* Veterans with SCI or Family caregivers of Veterans with SCI\n* Have access to the Internet and a computer to participate in a Zoom call\n* Able to speak and understand English to provide informed consent.\n\nExclusion Criteria:\n\n* Serious mental illness requiring psychiatric hospitalization",{"count":325,"type":20},100,"OBSERVATIONAL","Caregivers of persons with Spinal Cord Injury (SCI) face increased risk of psychological distress, health problems, reduced quality of life, relationship strain, and restrictions in social and work participation. Military caregivers (Family Caregivers of wounded or disabled Veterans) reported similar negative effects of becoming a caregiver on their physical and mental health.\n\nUsing results from our previous work in mHealth interventions for individuals with SCI, we developed a dual-target intervention for both individuals with SCI and their caregivers.\n\nThe overall objective of this research study is to conduct translational research focused on adapting and tailoring the interactive Mobile Health and Rehabilitation (iMHere) 2.0 system to meet the needs of Veterans with SCI and their family caregivers, expanding the psychosocial intervention, and evaluating the feasibility of implementing the iMHere system among Veterans with SCI and their family caregivers.",[329,330,331,27,332,333],"Spinal Cord Injuries (SCI)","Spinal Cord Injury","Spinal Cord Injuries (Complete and Incomplete)","Families of Veterans","Disabled Veterans",[330,335,336,337,338,339,340,341,342,343,344,345,346,347,348,349,350,351],"Veterans","Veterans with SCI","SCI","SCI\u002FD","Spinal Cord Injuries","Spinal Cord Disorder","Family caregiver","Primary caregiver","mobile health app","smartphone app","Imhere","Veterans support","paralyzed veterans","disabled veterans","mobile health support","mobile health","telemedicine","2025-12-05",{"date":354,"type":32},"2025-12-12",{"date":262,"type":32},{"date":357,"type":20},"2029-11",{"name":359,"class":39},"University of Pittsburgh",{"id":361,"slug":362,"hasResults":11,"nctId":363,"briefTitle":364,"officialTitle":364,"acronym":365,"eligibilityCriteria":366,"healthyVolunteers":48,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":367,"targetDuration":369,"studyType":326,"phases":4,"briefSummary":370,"conditions":371,"keywords":373,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":376,"lastUpdatePostDateStruct":377,"startDateStruct":379,"completionDateStruct":380,"leadSponsor":382,"locationsCount":4},"100612296","understanding-the-lived-experience-and-bereavement-of-caregivers-of-people-with-alzheimers-disease-100612296","NCT07251738","Understanding the Lived Experience and Bereavement of Caregivers of People With Alzheimer's Disease","ALCARE","Inclusion Criteria:\n\n* Inclusion criteria for Group 1: relatives of people diagnosed with AD by a neurologist or geriatrician, who have suffered the loss of a relative with AD; who have lived with and\u002For cared for the person with AD until the end of their life; who agree to participate voluntarily in the project and who have signed the informed consent form.\n* Inclusion criteria for Group 2: relatives of people diagnosed with AD by a neurologist or geriatrician; who live with and\u002For care for the person with AD; who attend the Day Centre and who agree to participate voluntarily in the project and have signed the informed consent form.\n* Inclusion criteria for Group 3: relatives of people diagnosed with AD by a neurologist or geriatrician; who have their relative institutionalised in a nursing home and who agree to participate voluntarily in the project and have signed the informed consent form.\n\nExclusion Criteria:\n\n* Those who have not lived with or cared for relatives with AD and who do not agree to participate in the study will be excluded from the project.",{"count":368,"type":20},66,"1 Day","The main objective of this study is to explore the lived experience of caregivers and family members of people with Alzheimer's disease (AD), from the beginning of caregiving through the bereavement process following the patient's death. Using a mixed-methods design, qualitative data will be collected through in-depth interviews and combined with quantitative data obtained from standardized scales. The results will aim to determine whether prolonged caregiving significantly affects the caregiver's or family member's personal, emotional, and occupational well-being, as well as whether it leads to a reorganization of activities of daily living (ADL), an increased perception of burden, and\u002For a decreased quality of life. The study will also examine the presence of positive adaptation experiences.",[195,372,27],"Occupational Therapy",[374,372,375],"Alzheimer's disease","occupational balance","2025-11-18",{"date":378,"type":32},"2025-11-26",{"date":262,"type":20},{"date":381,"type":20},"2026-07-31",{"name":383,"class":39},"Universidad Rey Juan Carlos",{"id":385,"slug":386,"hasResults":11,"nctId":387,"briefTitle":388,"officialTitle":389,"acronym":4,"eligibilityCriteria":390,"healthyVolunteers":11,"sex":16,"minAge":49,"maxAge":4,"enrollmentInfo":391,"targetDuration":4,"studyType":21,"phases":393,"briefSummary":394,"conditions":395,"keywords":4,"overallStatus":144,"whyStopped":4,"lastUpdateSubmitDate":399,"lastUpdatePostDateStruct":400,"startDateStruct":402,"completionDateStruct":404,"leadSponsor":406,"locationsCount":68},"100562039","dyadic-sport-stacking-program-for-mild-dementia-and-their-family-caregivers-100562039","NCT06597981","Dyadic Sport Stacking Program for Mild Dementia and Their Family Caregivers","Development and Testing of a Dyadic Empowerment-based Sport Stacking Program to Improve Health Outcomes of People With Mild Dementia and Their Family Caregivers","Inclusion Criteria:\n\n\\- People living with dementia (PLwD) : i) Clinical diagnosis of dementia, in accordance with the Diagnostic and Statistical Manual of Mental Disorders, fifth edition(DSM-V); ii) a minimum age of 60 years; iii) Clinical Dementia Rating (CDR) score of 1; iv) home-dwelling; v) able to communicate with the research personnel to understand training program and assessments; vi) have adequate hearing and visual function to enable skill learning; vii) informed consent.\n\n\\- Family caregivers: i) aged 18 years or above; ii) living with or providing care to PLwD at least 4 hours\u002Fday; iii) able to understand and communicate in Chinese; iv) have access to smartphone\u002FiPad\u002Flaptop and are users of one of these devices; v) consent to participate.\n\nExclusion Criteria:\n\n\\- People living with dementia (PLwD) : i) severe mental and behavioral disorders; ii) any acute medical condition precluding participation in the program (e.g., pneumonia and cardiac insufficiency); iii) concurrent participation in other studies.\n\n\\- Family caregivers: i) physically not able to participate in the sport stacking due to physical problems; ii) suffer from acute psychotic condition; iii) unable to support the PLwD in the delivery of sport stacking sessions.",{"count":392,"type":20},144,[53],"The goal of this clinical trial is to develop and test a dyadic empowerment-based sport stacking program to improve health outcomes of people with mild dementia and their family caregivers.\n\nThe research hypotheses to be tested are:\n\ni) People with dementia who receive the dyadic empowerment-based sport stacking program will report a greater improvement in cognitive function, a greater reduction in cognitive and neuropsychiatric symptoms, a greater reduction in depressive symptoms, and a greater improvement in health-related quality of life (HRQOL) at T1 (12th week) and T2 (18th week), compared to the usual care group; ii) Caregivers who receive the dyadic empowerment-based sport stacking program will report less stressful in managing the cognitive and neuropsychiatric symptoms, a greater reduction in depressive symptoms and a greater improvement in HRQOL at T1 (12th week) and T2 (18th week), compared to the usual care group; iii) The care dyads who receive the dyadic empowerment-based sport stacking program will report less dyadic relationship strain at T1 (12th week) and T2 (18th week), compared to the usual care group.\n\nFor the intervention group, the care dyads will receive an 18-week dyadic empowerment-based sport stacking program, which is divided into two phases: the active phase (weeks 1-12) and the maintenance phase (weeks 13-18). In the active phase, the care dyads will engage in three online sessions in small groups (3-5 dyads\u002Fgroup) and three check-up\u002Fsupport sessions. Three online sessions will be scheduled at weeks 1, 3, and 9 during the 12-week active phase. They will also be required to engage in self-practice at home for at least 30 minutes per day, five times per week during this time according to their training schedule. In the maintenance phase, there will be three online sessions in small groups (3-5 dyads\u002Fgroup). Three online sessions will be scheduled at weeks 13, 16, and 18. The dyads will continue their self-practice at home (at least 30 minutes\u002Fday, five times\u002Fweek) for 6 weeks.\n\nParticipants in the control group will receive basic education on dementia caregiving, which will comprise three group-based (3-5 dyads\u002Fgroup) online meetings in the same schedule as the intervention group (1st, 3rd, 9th week).",[170,27,396,397,398],"Dyadic Intervention","Health Related Quality of Life","Cognition","2025-11-17",{"date":401,"type":32},"2025-11-20",{"date":403,"type":32},"2024-09-19",{"date":405,"type":20},"2026-05-31",{"name":407,"class":39},"The University of Hong Kong",{"id":409,"slug":410,"hasResults":11,"nctId":411,"briefTitle":412,"officialTitle":413,"acronym":414,"eligibilityCriteria":415,"healthyVolunteers":48,"sex":16,"minAge":49,"maxAge":4,"enrollmentInfo":416,"targetDuration":4,"studyType":21,"phases":417,"briefSummary":418,"conditions":419,"keywords":426,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":434,"lastUpdatePostDateStruct":435,"startDateStruct":437,"completionDateStruct":439,"leadSponsor":441,"locationsCount":443},"100591772","the-family-cares-trial-100591772","NCT06984770","The Family Cares Trial","Caring for the Caregiver: A Pilot Randomized Controlled Trial (The Family Cares Trial)","Family Cares","Inclusion Criteria:\n\n* (1) Family member of a person admitted to an ICU for \\>48 hours and survived to hospital discharge. \"Family\" is anyone with a biological, legal, or emotional relationship with the patient and whom the patient wants involved in their care\n* (2) Planned or current part or full-time caregiver of the ICU survivor\n* (3) Age ≥ 18 years\n* (4) Within 6 months of ICU survivor's hospital discharge.\n\nExclusion Criteria:\n\n* (1) Another family member participating in the study\n* (2) Inability to communicate in English or French.",{"count":108,"type":20},[53],"The goal of this pilot study is to learn if virtual peer support groups and strengths-based skills training can help family caregivers of ICU survivors providing ongoing support to ICU survivors after hospital discharge. The main question it aims to answer is:\n\n\\- Are virtual peer support groups and\u002For strengths-based skills support feasible and acceptable for family caregivers of ICU survivors? Researchers will compare the intervention group (virtual peer support groups or strengths-based skills training) to the control group (no intervention) to see if the interventions improve caregiver outcomes and assess feasibility and acceptability.\n\nParticipants will:\n\n* Participate in either virtual peer support groups or strengths-based skills training sessions (if assigned to the intervention arm).\n* Provide feedback on the feasibility and acceptability of the interventions (if assigned to the intervention arm).\n* Complete surveys and follow-up questionnaires (either online or by phone) to measure outcomes.",[420,421,422,423,424,425,253,226,27],"Family Engagement","Critical Care, Intensive Care","Patient and Family Engagement","Health Care Delivery","Family-centered Care","Pilot Study",[427,420,428,429,430,431,432,56,433],"Patient- and Family-Centered Care","Critical Care","Intensive Care Unit","Person-Centered Care","Delivery of Health Care","Post-ICU","Family Caregiver","2025-05-14",{"date":436,"type":32},"2025-05-22",{"date":438,"type":20},"2025-08",{"date":440,"type":20},"2027-08",{"name":442,"class":39},"Lady Davis Institute",2]