[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"family-conflict\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:family-conflict":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,58,93,124],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":32,"overallStatus":45,"whyStopped":4,"lastUpdateSubmitDate":46,"lastUpdatePostDateStruct":47,"startDateStruct":50,"completionDateStruct":52,"leadSponsor":54,"locationsCount":57},"100648700","glycoquest-an-ai-adaptive-cgm-integrated-serious-game-for-pediatric-type-1-diabetes-100648700",false,"NCT07726680","GlycoQuest: An AI-Adaptive CGM-Integrated Serious Game for Pediatric Type 1 Diabetes","GlycoQuest: Glycemic and Psychosocial Outcomes of a CGM-Integrated, AI-Adaptive Serious Game Digital Therapeutic in Newly Diagnosed Pediatric Type 1 Diabetes: A Parallel-Group Randomized Controlled Trial","GlycoQuest","Inclusion Criteria:\n\n* Child or adolescent aged 6 to 17 years at enrollment.\n* Diagnosis of type 1 diabetes confirmed by a pediatric endocrinologist according to standard clinical criteria.\n* Type 1 diabetes diagnosed within the previous 3 months.\n* Primary caregiver aged 18 years or older willing to participate as part of a parent-child dyad.\n* Current use of continuous glucose monitoring or willingness to initiate CGM as part of standard diabetes care.\n* Household access to a compatible smartphone or tablet, or willingness to use a study-provided device if available.\n* Ability of child and caregiver to engage with study procedures and digital intervention content.\n* Caregiver able to provide written informed consent.\n* Child able to provide age-appropriate assent.\n\nExclusion Criteria:\n\n* Type 1 diabetes diagnosed more than 3 months before enrollment.\n* Concurrent participation in another intensive diabetes behavioral intervention trial.\n* Significant developmental, intellectual, visual, motor, or psychiatric condition that, in the opinion of the clinical team, would preclude meaningful engagement with the digital game interface or study procedures.\n* Acute psychiatric instability or safety concern requiring urgent specialist intervention.\n* Planned transfer to a different diabetes care provider within 6 months.\n* Absence of internet access that cannot be addressed by study support.","ALL","6 Years","17 Years",{"count":21,"type":22},110,"ESTIMATED","INTERVENTIONAL",[25],"NA","Type 1 diabetes diagnosed in childhood requires rapid acquisition of complex self-management skills while children and caregivers are also adapting emotionally and socially to a chronic condition. Standard diabetes education is often delivered early after diagnosis, is information intensive, and is not usually personalized to real-time glucose patterns, emotional state, child developmental stage, or family communication needs.\n\nThis study will evaluate GlycoQuest, an AI-adaptive, continuous glucose monitoring-integrated serious game digital therapeutic for children and adolescents newly diagnosed with type 1 diabetes and their primary caregivers. GlycoQuest uses CGM-linked gameplay, a glucose-responsive digital avatar, AI-personalized learning pathways, parent-child collaborative modules, adaptive hypoglycemia and insulin decision simulations, and psychosocial adaptation content addressing diabetes distress, fear of hypoglycemia, stigma, illness acceptance, and autonomy transition.\n\nThis randomized controlled trial will enroll 110 parent-child dyads. Children aged 6 to 17 years with type 1 diabetes diagnosed within the previous 3 months will be randomized 1:1 to GlycoQuest plus standard care or enhanced digital psychoeducation plus standard care. The intervention period will be 6 months, with follow-up to 8 months. The co-primary outcomes are change in CGM-derived time in range, defined as 70 to 180 mg\u002FdL, and child diabetes distress at 8 months. Secondary outcomes include time below range, glycemic variability, HbA1c, severe hypoglycemia, diabetic ketoacidosis readmissions, insulin omission, quality of life, fear of hypoglycemia, parental stress, diabetes family conflict, self-efficacy, engagement, and implementation outcomes.",[28,29,30,31],"Type 1 Diabetes Mellitus (T1DM)","Diabetes Distress","Hypoglycemia (Diabetic)","Family Conflict",[33,34,35,36,37,38,29,39,40,41,42,43,44],"Type 1 Diabetes","Pediatric Diabetes","Continuous Glucose Monitoring","Digital Therapeutic","Serious Game","Artificial Intelligence","Fear of Hypoglycemia","Family-Centered Care","Behavioral Medicine","Time in Range","Self-Efficacy","Implementation Science","RECRUITING","2026-07-21",{"date":48,"type":49},"2026-07-24","ACTUAL",{"date":51,"type":49},"2026-06-01",{"date":53,"type":22},"2026-11-30",{"name":55,"class":56},"Shifa International Hospital","OTHER",1,{"id":59,"slug":60,"hasResults":11,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":4,"eligibilityCriteria":64,"healthyVolunteers":11,"sex":17,"minAge":65,"maxAge":4,"enrollmentInfo":66,"targetDuration":4,"studyType":23,"phases":68,"briefSummary":69,"conditions":70,"keywords":79,"overallStatus":45,"whyStopped":4,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":57},"100616284","improving-outcomes-in-social-services-through-routine-outcome-monitoring-and-systematic-client-feedback-100616284","NCT07303608","Improving Outcomes in Social Services Through Routine Outcome Monitoring and Systematic Client Feedback","Empowering Clients, Preventing Dropout and Improving Outcomes Through Routine Outcome Monitoring and Systematic Client Feedback in Social Services","Inclusion Criteria:\n\nPeople who have been granted assistance under the Social Services Act at includes centers.\n\nExclusion Criteria:\n\n* People who do not have sufficient knowledge of Swedish or have impaired cognitive functions that prevent them from using FIT in Swedish, as they cannot benefit from the intervention that the study intends to evaluate the effects of. This is assessed by the respective social service.\n* People who receive support and treatment interventions that are not voluntary, i.e. interventions according to the Act on the Compulsory Care of Young People (LVU) or the Act on the Compulsory Care of Drug Abusers (LVM)","15 Years",{"count":67,"type":22},400,[25],"In this project the investigators want to test whether a new method FIT (Feedback informed treatment) can improve the interventions people receive through social services. The FIT method involves regularly providing information about how the client think things are going and what the client thinks about the help and care they receive.",[71,72,73,74,75,31,76,77,78],"Substance Use Disorders","Criminal Behavior","Domestic Violence","Social Care","Family Communication","Child Behavior Problem","Housing","Everyday Activities",[80,81,82,83],"Social services","Feedback informed treatment","Systematic client feedback","Routine outcome management","2025-12-18",{"date":86,"type":49},"2025-12-26",{"date":88,"type":49},"2025-12-05",{"date":90,"type":22},"2028-12-15",{"name":92,"class":56},"Karolinska Institutet",{"id":94,"slug":95,"hasResults":11,"nctId":96,"briefTitle":97,"officialTitle":98,"acronym":99,"eligibilityCriteria":100,"healthyVolunteers":101,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":102,"targetDuration":104,"studyType":105,"phases":4,"briefSummary":106,"conditions":107,"keywords":110,"overallStatus":114,"whyStopped":4,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":4},"100603269","from-conflict-to-family-trauma-100603269","NCT07134322","From Conflict to Family Trauma","From Conflict to Family Trauma - A Longitudinal Research for the Development of Best Practices in the Italian Legal System","FamilyTrauma","Inclusion Criteria:\n\n* Families with minor children who file a lawsuit\n* Parent-child relationships must have been severed with at least one parent.\n\nExclusion Criteria:\n\n\\- Families with adult children",true,{"count":103,"type":22},200,"12 Months","OBSERVATIONAL","This project will examine the experience of the researcher as expert in the family court dealing with questions regarding family units, in conflict and children, victims of the family conflict, victims of abuse and neglect, often repeated over time.After the first consultation, family conflict often recurs, without regard for the treatment received, returning to the civil courts and sometimes to the criminal courts. There are three possibilities at this point, following the first decision of the court (a) there is a separation that resolves conflicts and leads to an improvement in outcomes for the children concerned; (b) pre-existing conditions specific to the children concerned continue, and the decision of the court regading separation has no effect; (c) conflict between the parents continues, with repeated returns to the civil courts, failure of processes of mediation and negotiation, and continuing or exacerbated trauma to the child leading to worse outcomes; (d) where there is a worse outcome, this may be due to the lack of supports following the expert psychological assessment and recommendation to the court..The forensic evaluation of the family often refers the family to public health services for therapeutic interventions and social supports. The lack of these interventions and supports of public health services may exacerbate the family trauma. This may occur (a) because the family conflict continues in the absence of the interventions and supports; (b) because the family trauma is exacerbated by continuing court proceedings because the conflict between parents concerning the care and placement of the children leads to prolonged legal proceedings and may result in worse outcomes for the children, such as criminal behaviour as this struggle continues. The child is 'instrumentalised', used as a pawn or weapon in the struggle between the parents. The research project aims first of all to outline, on the basis of the data to be acquired, (a) whether there is evidence that the decision of the court guided by the expert opinion and recommendations has a beneficial effect on outcomes for the child; (b) specific lines of treatment intervention and better packages of care and support to enhance good outcomes and minimise or prevent these adverse outcomes, under the supervision of the judge.",[31,108,109],"Family Characteristics","Family Dysfunctional",[111,112,113],"Family Trauma","Higth Conflict","Therapeutic Jurisprudence","NOT_YET_RECRUITING","2025-08-20",{"date":117,"type":49},"2025-08-21",{"date":119,"type":22},"2026-02-08",{"date":121,"type":22},"2026-12-20",{"name":123,"class":56},"University of Bari Aldo Moro",{"id":125,"slug":126,"hasResults":11,"nctId":127,"briefTitle":128,"officialTitle":128,"acronym":4,"eligibilityCriteria":129,"healthyVolunteers":101,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":130,"targetDuration":4,"studyType":23,"phases":132,"briefSummary":133,"conditions":134,"keywords":137,"overallStatus":45,"whyStopped":4,"lastUpdateSubmitDate":141,"lastUpdatePostDateStruct":142,"startDateStruct":144,"completionDateStruct":146,"leadSponsor":148,"locationsCount":150},"100323783","families-of-youth-with-developmental-disabilities-a-theory-based-intervention-100323783","NCT03495440","Families of Youth with Developmental Disabilities: a Theory-Based Intervention","Inclusion Criteria:\n\n* Participants in all conditions will include mothers, fathers, TD siblings between 11 and 17 years old, and individuals with IDD of any age.\n* Participants must be able to understand and respond to survey questions in English\n* Parents must be cohabitating, with both participating children living in their home.\n* Individual with IDD falls into one or more of the following categories: 1) meets criteria for an intellectual disability, which would mean a measured IQ of 70-75 or lower and a measured Adaptive Functioning score of 70-75 or lower, 2) meets criteria for an Autism Spectrum Disorder based on an evaluation using the ADOS-2, SCQ, and expert clinical judgment based on DSM-5 ASD criteria, or 3) has a medically verified genetic condition (e.g., Down syndrome, Fragile X syndrome, Williams syndrome, Angelman syndrome, others) that is generally considered to be a developmental disability, and shows cognitive or adaptive functioning deficits (70-75 or below) although not necessarily deficits in both categories as would be needed for an Intellectual Disability diagnosis.\n\nExclusion Criteria:\n\n* Siblings identified as typically developing will be excluded 1) with a score of 10 or higher on the SCQ-L, if a subsequent ADOS suggests that they have an ASD diagnosis, or 2) with a WASI-II score of 75 or lower.",{"count":131,"type":22},150,[25],"This study is designed to evaluate a preventive intervention program designed to support families (parents and typically developing adolescent siblings) that include a child with an intellectual and\u002For developmental disability. Participant families will be randomly assigned to either the treatment condition, in which they will receive psychoeducation and communication coaching over a four-week period, or the control condition, in which they will receive self-study materials. All subjects will participate in a pre-test assessment and three post-test assessments over the course of the year.",[31,135,136],"Marital Conflict","Communication",[138,139,140],"Emotional Security","Intellectual Disability","Developmental Disability","2024-11-13",{"date":143,"type":49},"2024-11-15",{"date":145,"type":49},"2017-08-04",{"date":147,"type":22},"2024-12-31",{"name":149,"class":56},"University of Notre Dame",2]