[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"fascia-iliaca-block\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:fascia-iliaca-block":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,46,72,98],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100651586","ficb-for-hip-fracture-pain-in-elderly-100651586",false,"NCT07762846","FICB for Hip Fracture Pain in Elderly","The Early Intervention of Fascia Iliaca Compartment Block (FICB) as Pain Management for Elderly Patients With Hip Fracture to Improve Postoperative Rehabilitation: A Prospective Randomized Controlled Study","FICB-PREP","Inclusion Criteria:\n\n* Age ≥ 65 years\n* Diagnosis of unilateral hip fracture (including femoral neck fracture or intertrochanteric fracture) confirmed by any imaging modality (X-ray, CT, or MRI)\n* Scheduled for hip fracture surgery under general anesthesia with endotracheal intubation (including total hip arthroplasty, hemiarthroplasty, intertrochanteric intramedullary nail fixation, closed reduction and internal fixation, etc.)\n* American Society of Anesthesiologists (ASA) physical status classification I-III\n* Able to provide written informed consent personally or via a legally authorized representative\n* Able to communicate normally in Chinese\n\nExclusion Criteria:\n\n* Known allergy to ropivacaine, bupivacaine, or liposomal bupivacaine\n* Presence of any contraindication to nerve block, including but not limited to: nerve injury, coagulopathy, severe infection at the injection site, exudate at the injection site, etc.\n* Pre-existing psychiatric or neurological disorders, including but not limited to: depression, severe central nervous system depression, Parkinson's disease, basal ganglia lesions, schizophrenia, epilepsy, Alzheimer's disease, myasthenia gravis\n* Pre-existing severe cardiac, pulmonary, hepatic, or renal dysfunction, including but not limited to: history of heart failure, requiring dialysis, etc.\n* Inability to communicate preoperatively (e.g., coma, dementia)\n* Preoperative pain score \\\u003C 4 on Visual Analog Scale (VAS) or chronic\u002Fold hip fracture\n* Currently participating in another interventional clinical trial\n* Any other condition that, in the opinion of the investigator, would preclude evaluation of the therapeutic response or make it unlikely that the patient will complete the expected treatment course and follow-up","ALL","65 Years",{"count":20,"type":21},144,"ESTIMATED","INTERVENTIONAL",[24],"NA","Hip fracture is a common injury in elderly patients, often requiring surgical treatment. However, these patients frequently experience severe postoperative pain, which can delay mobility and recovery, and increase the risk of complications such as delirium, pneumonia, and prolonged hospital stay.\n\nThe fascia iliaca compartment block (FICB) is a regional anesthesia technique that has been shown to provide effective pain relief for hip fracture patients. This study aims to investigate whether early administration of FICB, performed upon hospital admission before surgery, can improve postoperative rehabilitation outcomes in elderly patients with hip fracture.\n\nThis is a prospective, randomized, controlled study. A total of 144 elderly patients with hip fracture will be randomly assigned to either the FICB group or the control group. The FICB group will receive ultrasound-guided FICB after being admitted to the orthopaedic ward, while the control group will receive standard analgesic care once inside the operating room.\n\nThe primary outcome measure is Quality of Recovery-15 score (QoR-15 score) 24 hours post-surgery. Secondary outcomes include: QoR-15 score at 48 hours postoperatively, NRS scores and sleep duration and quality scores at preoperative and various postoperative time points, total perioperative consumption of opioids and other analgesic drugs, extubation time and emergence agitation during anesthesia recovery period, incidence of delirium from postoperative period to before discharge, length of hospital stay, and overall satisfaction score with pain management.\n\nThe hypothesis of this study is that early FICB intervention, compared to standard care, will lead to better pain control, earlier mobilization, shorter hospital stay, and improved overall postoperative recovery in elderly patients with hip fracture.",[27,28,29,30,31,32],"Hip Fractures (i.e. Femoral Neck or Intertrochanteric Hip Fractures)","Postoperative Pain","QoR-15","Fascia Iliaca Block","Recovery of Function (G11.427.698.620)","Elderly","NOT_YET_RECRUITING","2026-08-12",{"date":36,"type":37},"2026-08-13","ACTUAL",{"date":39,"type":21},"2026-08",{"date":41,"type":21},"2027-12",{"name":43,"class":44},"RenJi Hospital","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":17,"minAge":53,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":22,"phases":56,"briefSummary":58,"conditions":59,"keywords":62,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":68,"leadSponsor":70,"locationsCount":45},"100642566","phase-4-fascia-iliaca-block-using-liposomal-bupivacaine-for-analgesia-after-hip-fracture-surgery-100642566","NCT07643792","Fascia Iliaca Block Using Liposomal Bupivacaine for Analgesia After Hip Surgery","Fascia Iliaca Block Using Liposomal Bupivacaine for Analgesia After Hip Surgery: a Randomized Trial","Inclusion Criteria:\n\n* Aged ≥ 18 years.\n* Scheduled to undergo hip replacement surgery.\n* Agree to receive regional nerve block and postoperative patient-controlled intravenous analgesia (PCIA).\n\nExclusion Criteria:\n\n* Inability to communicate due to visual, auditory, language, or other reasons before surgery.\n* Chronic opioid dependence and long-term use of various types of analgesics (for more than 3 months).\n* Severe coagulation abnormalities (International Normalized Ratio \\> 1.7, activated partial thromboplastin time exceeding the normal value by more than 4 seconds, platelet count \\\u003C 80 × 10⁹\u002FL), trauma or infection at the intended puncture site, or severe low back pain.\n* Preoperative severe renal insufficiency (serum creatinine \\> 442 μmol\u002FL or requiring renal replacement therapy), hepatic insufficiency (Child-Pugh class C), or ASA physical status \\> IV.\n* Known allergy to local anesthetics.\n* Any other condition that the investigator or attending physician deems unsuitable for participation in the study.","18 Years",{"count":55,"type":21},148,[57],"PHASE4","Patients after hip surgery often suffer from severe pain. Inadequate analgesia increases the risk of postoperative delirium, myocardial injury, and other complications. Peripheral nerve block is an important component of multimodal analgesia, but conventional local anesthetics (such as plain bupivacaine) provide only approximately 12 hours of analgesic duration, which is far from covering the most painful 72 hours after surgery. Liposomal bupivacaine has a slow-release property, prolonging the analgesic duration up to 72 hours after a single injection. However, its clinical advantages in hip fracture surgery remain controversial. The investigators suppose that, compared with plain bupivacaine alone, preoperative supra-inguinal fascia iliaca block using liposomal bupivacaine combined with plain bupivacaine can further improve analgesia, decrease opioid consumption, and improve postoperative recovery quality within 72 hours in older patients after hip fracture surgery.",[30,60,28,61],"Liposomal Bupivacaine","Hip Surgery",[30,60,28,63],"Hip surgery","2026-08-08",{"date":66,"type":37},"2026-08-11",{"date":39,"type":21},{"date":69,"type":21},"2028-08",{"name":71,"class":44},"Peking University First Hospital",{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":4,"eligibilityCriteria":78,"healthyVolunteers":11,"sex":17,"minAge":53,"maxAge":79,"enrollmentInfo":80,"targetDuration":4,"studyType":22,"phases":82,"briefSummary":83,"conditions":84,"keywords":4,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":45},"100575553","transcatheter-aortic-valve-implantation-comparison-of-the-effects-of-ultrasound-guided-pericapsular-nerve-group-block-and-fascia-iliaca-block-on-postoperative-analgesia-management-100575553","NCT06773780","Transcatheter Aortic Valve Implantation: Comparison of the Effects of Ultrasound-Guided Pericapsular Nerve Group Block and Fascia Iliaca Block on Postoperative Analgesia Management","Transcatheter Aortic Valve Implantation: Comparison of the Effects of Ultrasound-Guided Pericapsular Nerve Group Block and Fascia Iliaca Block on Postoperative Analgesia Management - A Randomized, Prospective Study","Inclusion Criteria:\n\n* Patients scheduled for TAVİ\n* aged between 18 and 85 years,\n* American Society of Anesthesiology (ASA) physical status II-IV\n\nExclusion Criteria:\n\n* History of bleeding diathesis.\n* Use of anticoagulant therapy.\n* History of chronic pain prior to surgery.\n* Multiple trauma.\n* Conditions where pain assessment cannot be performed (e.g., dementia).\n* Patients operated under spinal or epidural anesthesia.\n* Presence of infection in the region where the block will be applied.\n* Refusal to consent to the procedure","85 Years",{"count":81,"type":21},60,[24],"Aortic Stenosis (AS) is the most common valvular pathology, particularly prevalent in advanced age, and Transcatheter Aortic Valve Implantation (TAVI) has become a crucial treatment option for high-risk patients who are not suitable for surgery. This minimally invasive approach has demonstrated successful clinical outcomes in patients deemed ineligible for surgical procedures.\n\nPatient selection criteria and advancements in operative techniques are critical for achieving successful TAVI outcomes. While the transfemoral approach is the most commonly used method, alternative techniques such as transapical, transaxillary, transcarotid, and transaortic approaches are also available.\n\nThe Pericapsular Nerve Group Block (PENG) targets the femoral and accessory obturator nerves, providing analgesia to the anterior hip without causing motor block. The Fascia Iliaca Block (FIB), on the other hand, provides broader analgesic coverage by affecting the lateral femoral cutaneous, obturator, and femoral nerves.\n\nThis study aims to compare PENG block, FIB, and local infiltration anesthesia in TAVI patients regarding sedation requirements during the procedure and postoperative analgesia management. Additionally, pain scores, motor block presence, opioid consumption, and side effects will be assessed. The study seeks to identify optimal strategies to enhance patient comfort and safety during TAVI procedures.",[85,86,87,30],"Aortic Valve Stenosis","Transcatheter Aortic Valve Implantation","Pericapsular Nerve Group Block","RECRUITING","2026-07-24",{"date":91,"type":37},"2026-07-27",{"date":93,"type":37},"2025-01-10",{"date":95,"type":21},"2026-12-01",{"name":97,"class":44},"Medipol University",{"id":99,"slug":100,"hasResults":11,"nctId":101,"briefTitle":102,"officialTitle":102,"acronym":4,"eligibilityCriteria":103,"healthyVolunteers":11,"sex":17,"minAge":53,"maxAge":18,"enrollmentInfo":104,"targetDuration":4,"studyType":22,"phases":106,"briefSummary":108,"conditions":109,"keywords":111,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":45},"100563272","phase-1-effect-of-different-administration-routes-of-dexmedetomidine-combined-with-ultrasound-guided-fascia-iliaca-block-on-emergence-agitation-after-hip-replacement-surgery-100563272","NCT06614010","Effect of Different Administration Routes of Dexmedetomidine Combined with Ultrasound-Guided Fascia Iliaca Block on Emergence Agitation After Hip Replacement Surgery","Inclusion Criteria:\n\n1. age between 18 and 65 years, with no restriction on gender\n2. diagnosis of hip joint disease necessitating hip arthroplasty\n3. ASA grade I-II\n4. no significant cardiopulmonary, hepatic, or renal dysfunction prior to the operation\n5. no history of psychiatric disorders or long-term use of sedative medications prior to the operation\n6. signing of an informed consent form to voluntarily participate in the study.\n\nExclusion Criteria:\n\n1. patients allergic to or with contraindications to ropivacaine or dexmedetomidine\n2. patients exhibiting symptoms of agitation or delirium prior to the procedure\n3. patients with severe central or peripheral nervous system disorders\n4. patients with coagulation disorders or receiving anticoagulant therapy\n5. pregnant or breastfeeding women\n6. patients who received other medications or treatments prior to the procedure that might affect the study results\n7. patients unable to cooperate with the study or intolerant to ultrasound-guided iliofascial block",{"count":105,"type":21},207,[107],"PHASE1","To examine the impact of various administration routes of dexmedetomidine in conjunction with ultrasound-guided fascia iliaca block (FIB) on emergence agitation (EA) during the postoperative recovery period after hip replacement surgery.",[110,30],"Dexmedetomidine",[30,110,112,113,114],"Emergence Agitation","Ropivacaine","Analgesic Mechanism","2024-09-23",{"date":117,"type":37},"2024-09-26",{"date":119,"type":37},"2023-02-05",{"date":121,"type":21},"2025-12-01",{"name":123,"class":44},"Qianfoshan Hospital"]