[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"fetuin-a\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:fetuin-a":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":4},"100657803","metabolic-and-hormonal-parameters-in-women-with-polyendocrine-metabolic-ovarian-syndrome-100657803",false,"NCT07844785","Metabolic and Hormonal Parameters in Women With Polyendocrine Metabolic Ovarian Syndrome","Correlation of Serum and Salivary Fetuin-A and Resistin Levels With Metabolic and Hormonal Parameters in Women With Polyendocrine Metabolic Ovarian Syndrome","PMOS-FR","Inclusion Criteria:\n\nPMOS Group:\n\n* Female, aged 18-35 years\n* Diagnosis of Polyendocrine Metabolic Ovarian Syndrome (PMOS) according to the Rotterdam criteria\n* BMI \\\u003C30 kg\u002Fm²\n* Written informed consent\n\nHealthy Control Group:\n\n* Female, aged 18-35 years\n* Regular menstrual cycles\n* No diagnosis of PMOS\n* BMI \\\u003C30 kg\u002Fm²\n* Written informed consent\n\nExclusion Criteria:\n\n* Pregnancy or breastfeeding\n* Diabetes mellitus\n* Chronic kidney or liver disease\n* Thyroid dysfunction\n* Hyperprolactinemia\n* Cushing syndrome\n* Non-classic congenital adrenal hyperplasia\n* Use of hormonal contraceptives, anti-androgens, glucocorticoids, metformin, or insulin-sensitizing medications within the previous 3 months\n* Severe periodontal disease or active oral infection",true,"FEMALE","18 Years","35 Years",{"count":22,"type":23},80,"ESTIMATED","OBSERVATIONAL","Polyendocrine Metabolic Ovarian Syndrome (PMOS) is a common endocrine and metabolic disorder associated with insulin resistance, hyperandrogenism, and an increased risk of long-term metabolic complications. Fetuin-A and resistin are adipokines implicated in insulin resistance and chronic inflammation and may serve as potential biomarkers for metabolic dysfunction in women with PMOS.\n\nThis prospective observational case-control study aims to compare serum and salivary Fetuin-A and resistin levels between women with PMOS and healthy controls. The study will evaluate the correlation between serum and salivary biomarker concentrations and investigate their associations with insulin resistance, lipid profile, and hormonal parameters. The findings may help determine whether salivary measurements can serve as reliable non-invasive biomarkers for the diagnosis and metabolic assessment of PMOS.",[27,28,29,30,31],"Polycystic Ovary Syndrome","Polycystic Ovary Syndrome (PCOS) Women","Fetuin-A","Serum Biomarkers","Insulin Resistance","NOT_YET_RECRUITING","2026-09-22",{"date":35,"type":36},"2026-09-28","ACTUAL",{"date":38,"type":23},"2026-09-01",{"date":40,"type":23},"2027-08-30",{"name":42,"class":43},"Istinye University","OTHER"]