[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"food-cravings\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:food-cravings":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,51],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":4},"100651223","effects-of-home-based-transcranial-direct-current-stimulation-on-appetite-100651223",false,"NCT07757438","Effects of Home-Based Transcranial Direct Current Stimulation on Appetite","Neurophysiological Effects of Transcranial Direct Current Stimulation on Appetite: Randomized, Placebo-Controlled, Double-Blind, Parallel-Design","Inclusion Criteria:\n\n* Adults aged 19 to 65 years\n* Binge Eating Scale (BES) score ≥18\n* BMI ≥18.5 kg\u002Fm²\n* No significant weight loss or lifestyle changes during the previous 3 months\n* Stable chronic medical conditions (e.g., hypertension, diabetes, dyslipidemia) are allowed\n* Able to use an Android smartphone compatible with the study application (including a study phone if provided)\n* Able and willing to provide written informed consent\n\nExclusion Criteria:\n\n* Unable to understand the study procedures or provide informed consent\n* Implanted pacemaker, implantable cardioverter-defibrillator, deep brain stimulator, cochlear implant, coronary stent, or other implanted metallic medical devices (dental implants and joint prostheses are allowed)\n* Diagnosis or treatment for a psychiatric or neurological disorder within the previous 3 months\n* Use of medications affecting appetite or body weight within the previous month\n* Use of medications affecting eating behavior or mood within the previous month\n* Pregnant or breastfeeding\n* Any medical condition judged by the investigator to interfere with study participation or interpretation of study results",true,"ALL","19 Years","65 Years",{"count":21,"type":22},100,"ESTIMATED","INTERVENTIONAL",[25],"NA","This randomized, placebo-controlled, double-blind, parallel-design study aims to evaluate the neurophysiological effects of home-based transcranial direct current stimulation (tDCS) on appetite in adults with binge eating tendencies.\n\nParticipants will be randomly assigned to either an active tDCS group or a sham stimulation group. After baseline assessments, participants will self-administer home-based tDCS twice daily for 4 weeks using a wearable wellness device. Appetite, eating behavior, body composition, dietary intake, and psychological outcomes will be assessed throughout the study to evaluate both the acute and chronic effects of repeated tDCS.",[28,29,30],"Appetite","Binge Eating Behaviour","Food Cravings",[32,33,28,34,35,36,37,38],"Transcranial Direct Current Stimulation","tDCS","Food Craving","Binge Eating","Eating Behavior","Home-based Intervention","Neuromodulation","NOT_YET_RECRUITING","2026-08-07",{"date":42,"type":43},"2026-08-11","ACTUAL",{"date":45,"type":22},"2026-08-15",{"date":47,"type":22},"2027-04-30",{"name":49,"class":50},"Seoul National University Hospital","OTHER",{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":19,"enrollmentInfo":58,"targetDuration":4,"studyType":23,"phases":60,"briefSummary":61,"conditions":62,"keywords":64,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":78},"100601123","the-effectiveness-of-rtms-on-improving-food-craving-and-weight-control-in-adults-without-serious-mental-illness-100601123","NCT07106398","The Effectiveness of rTMS on Improving Food Craving and Weight Control in Adults Without Serious Mental Illness","Inclusion Criteria:\n\n* Healthy adults\n* Aged between 18-65\n* Self-reported food craving or weight control issues\n\nExclusion Criteria:\n\n* People with serious mental illness\n* Severe neurological conditions\n* Contraindications for rTMS\n* People on weight-reduction medications","18 Years",{"count":59,"type":22},30,[25],"Department of Psychiatry \\| Li Ka Shing Faculty of Medicine\n\nThe University of Hong Kong\n\nThe Effectiveness of rTMS on Improving Food Cravings and Weight Control\n\nin Adults without Serious Mental Illness\n\nIntroduction\n\nThe investigators would like to invite participants to participate in an observational study on the efficacy of using magnetic fields to improve food cravings and weight control in adults without serious mental illness.\n\nThe research leader is Dr. Cheng Pak Wing, Assistant Professor, Department of Psychiatry, Queen Mary Hospital\u002FHKU Li Ka Shing Faculty of Medicine.\n\nPlease read the following information carefully. If necessary, participants can discuss it with relatives, friends or doctors. If anything is unclear, or if participants would like more information, please ask us. Please carefully consider whether participants are willing to participate in this research.\n\nResearch Purpose\n\nFood cravings are a common experience that can significantly impact an individual's mental and physical health. These intense desires for specific foods often lead to overconsumption of unhealthy foods, contributing to obesity, poor nutritional intake, and associated health conditions. Understanding the neural mechanisms behind food cravings is crucial for developing effective interventions to manage them.\n\nrTMS is a non-invasive brain stimulation technique that uses magnetic fields to modulate neural activity in targeted brain regions. Over the years, rTMS has shown promise in treating various mental health conditions, including depression, obsessive-compulsive disorder (OCD) and eating disorders.\n\nResearch Methods\n\nParticipants\n\nHealthy adults aged 18-65 with self-reported food cravings or weight control issues.\n\nTreatment protocol\n\nSix sessions of rTMS using the EXOMIND™ device, administered once or twice a week.\n\nEach session will deliver 6,300 pulses at alternating frequencies of 12, 15, and 18 Hz, with a total duration of 24 minutes and 30 seconds.\n\nThe target site would be left dorsolateral prefrontal cortex (DLPFC), determined by the most common used 5-cm rule. The procedure would be conducted in the research centre with medical staff supported.\n\nA checklist of potential adverse effects from TMS administration will be referenced from existing literature to monitor tolerability and adverse events during each session. Blood pressure and heart rate will be recorded at the beginning and end of each session.\n\nAssessment\n\nParticipants will be assessed at three time points: baseline (pre-intervention), post-intervention, and four weeks post-intervention.\n\nAssessments: Food Cravings Questionnaire-Trait (FCQ-T), Perceived Stress Scale (PSS), Patient Health Questionnaire-9 (PHQ-9), and BMI.\n\nDemographics: Age, gender, years of education, place of birth, marital status, number of children, financial condition, household income, family history of eating problems will be collected upon study entry. Medical history in relation to mental illnesses and medications will also be assessed.",[30,63],"rTMS",[65,66,67],"rtms","food cravings","healthy adults","RECRUITING","2025-08-06",{"date":71,"type":43},"2025-08-11",{"date":73,"type":43},"2025-07-04",{"date":75,"type":22},"2028-06-27",{"name":77,"class":50},"The University of Hong Kong",1]