[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"gait\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:gait":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,22,0,[8,51,94,136,164,195,225,250,273,293,310,336,368,396,421,445,469,493,521,552,572,594],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100652708","effects-of-otago-exercise-versus-multisensory-integration-training-on-balance-and-gait-in-elderly-with-diabetes-100652708",false,"NCT07776535","Effects Of Otago Exercise Versus Multisensory Integration Training On Balance And Gait In Elderly With Diabetes","Balance - DM","Inclusion Criteria:\n\n1. Ninety elderly Patients of both genders.\n2. Their age will range from 65 to 75th.\n3. They will be diagnosed with type 2 diabetes for 5 years or more.\n4. Patients with mild \\& moderate neuropathy will be included. (Based on the Toronto scale: -mild (6-8); moderate (9-11)\n5. Berg balance between (21 to \\\u003C50) patients with mild \\&moderate risk of fall .\n6. Time up \\& go dual task: patient takes longer than 10 sec.\n7. HBA1C for these patients was ≥ 6.5% .\n8. BMI will range from (18: 29,9 kg\u002Fm2).\n9. Able to walk independently, with or without assistive devices.\n\nExclusion Criteria:\n\n1. Any musculoskeletal disorder affecting the lower limb (fracture of the lower limb, tumors, any infection, ligament injuries, foot injuries).\n2. Any other neurological disorder influences gait such as (stroke, Parkinson's disease, cerebellar dysfunction, ataxia, vestibular disorders)\n3. Any other cardiovascular disease (arrhythmia, cardiac pacemakers).\n4. Unstable proliferative retinopathy and visual impairments without correction.\n5. Non-diabetic neuropathy (inflammatory, autoimmune disease, infections, tumors, vitamin B12 deficiency, hypothyroidism, alcoholism, injury or pressure on the nerve).\n6. The use of medications significantly impacting postural control (e.g., sedatives).\n7. Vestibular system and Cognitive disorders.\n8. Uncontrolled hypertension.\n9. Common peroneal nerve injury.\n10. Orthostatic hypotension.","ALL","65 Years","75 Years",{"count":20,"type":21},90,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to compare the effect of the Otago exercise and Multisensory integration training on balance and gait in the elderly with type 2 diabetes mellitus.\n\nThe main question it aims to answer is:\n\n• Is there a significant difference between the effect of Otago exercise and Multisensory integration training on balance and gait in the elderly with type 2 diabetes mellitus? Researchers will compare Otago exercise to Multisensory integration training to know which one has the greatest benefit on balance \\&gait in the elderly with type2 diabetes.\n\nParticipants will be divided into 3 groups; each group takes a certain training program for 8 weeks:\n\n* First group: Otago exercise group plus conventional treatment for neuropathy.\n* Second group: Multisensory integration training group plus conventional treatment for neuropathy.\n* Third group: control group takes only conventional treatment for neuropathy.",[27,28,29],"Balance","Gait","Diabetes Mellitus",[31,32,33,34,35,36,37],"otago exercise","multisensory integration","balance disorder","gait proplem","diabetes","elderly","older adults","NOT_YET_RECRUITING","2026-08-17",{"date":41,"type":42},"2026-08-20","ACTUAL",{"date":44,"type":21},"2026-10",{"date":46,"type":21},"2027-11",{"name":48,"class":49},"Cairo University","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":57,"sex":16,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":4,"studyType":22,"phases":62,"briefSummary":63,"conditions":64,"keywords":68,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":87,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":50},"100652548","sensor-ankle-brace-for-special-operations-rehabilitation---phase-2-100652548","NCT07776223","Sensor Ankle Brace for Special Operations Rehabilitation - Phase 2","Inclusion Criteria:\n\n* Healthy adults: ages 18 - 40 years\n* considered \"healthy to exercise\" as determined by the physical activity readiness questionnaire (PAR-Q)\n* Classified as \"moderate\" or \"high\" activity level as defined by the scoring criteria of the International Physical Activity Questionnaire - Short Form (IPAQ)\n* Comfortably fit into combat boots provided by the laboratory (Men's sizes 8, 9, 10, 11, 12 and Women's sizes 6, 7, 8, 9, 10 will be purchased, and so participants with foot lengths of 22.54-29.27.8 cm are expected to fit in the boots provided).\n\nExclusion Criteria:\n\n* Smoking tobacco on a regular basis\n* Previous lower back or lower limb surgery (including the joints of the pelvis and lower limbs)\n* Musculoskeletal injury sustained within the 12-weeks prior to enrollment . A musculoskeletal injury is defined as musculoskeletal pain causing a reduction or stoppage of normal physical activity for at least 3 days within a 7-day period, and have not returned to their normal physical activity and exercise without pain for at least the last 6-weeks.\n* Pregnant (women only)\n* Current or history of an unresolved musculoskeletal, neurological, cardiovascular, pulmonary\u002Frespiratory, metabolic, renal condition, disease, or problem.\n* Torn anterior or posterior cruciate ligament (ACL or PCL).\n* Any other disease or problems that may affect movement or the ability to exercise even at a low intensity.\n* Identification of Functional Ankle Instability (IDFAI) score of \\\u003C11.\n* unable to comfortably perform the drop landing condition.\n* Feet are too large or too small to fit comfortably in the combat boots provided.",true,"18 Years","40 Years",{"count":61,"type":21},40,[24],"The primary purpose of this study overall is to validate a modified version of a commercially available ankle brace. Inertial measurement unit sensors will be incorporated into an existing ankle brace (\"sXAB\") by TayCo Brace, Inc. In two consecutive studies, gait metrics data collected from the sensor enabled ankle brace will be compared to data collected by the gold-standard equipment that is used in research and clinical settings to determine whether the sXAB performs adequately in terms of measurement or technical feasibility prior to further clinical evaluation. In the Phase 2 protocol, the sXAB will be validated on healthy subjects wearing combat boots performing walking, running, jumping, and stair climbing activities. These movements were selected because they simulate key movements performed during operational activities. All participants experience both conditions: with an ankle brace and without an ankle brace. Comparisons are made within-subject between brace and no-brace conditions. It is hypothesized that the sensor-enabled ankle brace will measure gait metrics with a high degree of accuracy (within 5%) when compared against the gold-standard lab equipment (i.e., motion capture and research-grade inertial measurement units).",[28,27,65,66,67],"Biomechanical Data","Postural Control","Locomotion",[69,70,71,72,73,74,75,76,77,78,79,80,81,82,83,84,85],"adult","gait","gait analysis","humans","ankle brace","motion capture","sensor validation","wearable electronic devices","wearable sensors","inertial measurement unit","IMU","locomotion","running","walking","landing","stair ascent","stair descent","RECRUITING",{"date":41,"type":42},{"date":89,"type":42},"2026-05-05",{"date":91,"type":21},"2026-09-01",{"name":93,"class":49},"Indiana University",{"id":95,"slug":96,"hasResults":11,"nctId":97,"briefTitle":98,"officialTitle":99,"acronym":4,"eligibilityCriteria":100,"healthyVolunteers":11,"sex":16,"minAge":58,"maxAge":101,"enrollmentInfo":102,"targetDuration":4,"studyType":22,"phases":104,"briefSummary":105,"conditions":106,"keywords":113,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":126,"lastUpdatePostDateStruct":127,"startDateStruct":129,"completionDateStruct":131,"leadSponsor":133,"locationsCount":135},"100646434","closed-loop-vagus-nerve-stimulation-clv-for-recovery-of-gait-after-spinal-cord-injury-sci-100646434","NCT07689227","Closed-Loop Vagus Nerve Stimulation (CLV) for Recovery of Gait After Spinal Cord Injury (SCI)","Early Feasibility Study of the ReWire System for Closed-Loop Vagus Nerve Stimulation (CLV) Paired With Rehabilitation After Spinal Cord Injury (SCI) - Lower Limb Study","Inclusion Criteria:\n\n1. Ability to provide signed and dated informed consent.\n2. Willingness and ability to comply with all study procedures and protocol requirements for the duration of the study.\n3. Age 18 to 64 years.\n4. Chronic, non-penetrating, motor incomplete spinal cord injury \\[Association Impairment Scale (AIS) grade C or D\\] occurring ≥12 months prior to enrollment, resulting in impairment in lower limb function.\n5. Ambulatory with residual gait impairment attributable to spinal cord injury.\n6. Self-selected gait speed of \\\u003C 0.8 m\u002Fs as measured by the 10 meter walk test.\n7. Score of 2 or less on at least 4 measures on the Ambulation subsection of the SCI-Functional Independence scale (SCI-FIS).\n8. In otherwise good general health as determined by medical history and physical examination.\n9. Meets all clinical criteria for VNS implantation as determined by the Site PI and clinical care team.\n\nExclusion Criteria:\n\n1. Any history of spinal cord injuries by penetrating traumatic, non-traumatic or congenital causes.\n2. Evidence of right-sided recurrent laryngeal nerve injury on pre-operative laryngoscopy, if required (Note: Participants with a history of right-sided anterior cervical surgery must undergo laryngoscopy prior to surgical scheduling. A finding of right-sided recurrent laryngeal nerve injury results in exclusion).\n3. Excessive scar tissue on intraoperative assessment that precludes safe implantation (Note: Participants with a history of left-sided anterior cervical surgery will undergo intraoperative assessment of scar tissue. If excessive scar tissue is deemed to preclude safe implantation, the procedure will be abandoned and the participant excluded for safety reasons. A history of left-sided anterior cervical surgery or prior recurrent laryngeal nerve injury alone does not result in exclusion).\n4. Concomitant clinically significant brain injuries.\n5. Deficits in language or attention that interfere with study participation.\n6. Presence of any other implanted electrical stimulation device.\n7. Prior injury to the vagus nerve.\n8. Presence of any other implanted investigational device.\n9. Neck circumference of \\> 18.5 inches or significant overlying tissue and\u002For scarring that may hinder device communication.\n10. Psychiatric, psychosocial, and\u002For cognitive disorder or impairment that could interfere with study participation as assessed by medical evaluation.\n11. Current or past: (a) medical (psychiatric, non-psychiatric) condition, disease, disorder, injury, or disability\\*; or (b) non-medical situation or circumstance that, in the opinion of the Site PI, study participation:\n\n    1. may pose a significant or undue risk to the person;\n    2. make it unlikely the person will complete all the study requirements per protocol; or\n    3. may adversely impact the integrity of the data or the validity of the study results.\n\n    \\[\\*Examples include, but are not limited to, the following types of conditions, diseases or disorders: renal insufficiency or failure, vascular disease, unstable or concerning cardiac disease, endocrinologic concerns (e.g., poorly controlled diabetes), immunosuppression, respiratory issues, psychiatric (e.g., schizophrenia), neurologic (e.g., cognitive, seizure), sickle cell disease, lupus, clotting disorders, active neoplastic disease (excluding basal or squamous cell carcinoma of the skin with intent for curative excision), recent documented history (within the last 3 months) of dysphagia or aspiration difficulty\\]\n12. Is female and lactating, pregnant, or plans to become pregnant during the study. Participants of child-bearing potential that are sexually active must use a reliable form of birth control. Acceptable birth control methods: (a) sterilization surgery for women, (b) surgical sterilization implant for women, (c) sterilization surgery for men (including all male partners), (d) Long-acting reversible contraceptives (LARC)-implantable rod and Intrauterine Device (IUD), (e) contraceptive shots\u002Finjection every 3 months, (f) oral contraceptives (pills), (g) contraceptive patch, (h) vaginal contraceptive ring, and (i) complete abstinence.\n13. Abusive use of alcohol or drugs that could interfere with participation, as determined by the Site PI.\n14. Concurrently participating in another interventional clinical study.\n15. Requires or plans the use of diathermy, transcranial magnetic stimulation, or electroconvulsive therapy (ECT) during the course of the study.\n16. Is known to be under incarceration or legal detention as determined by the Site PI.\n17. Non-English speaking, unless the enrolling site has an IRB-approved translated consent and qualified medical interpreter resources available in the participant's language to support all study visits and procedures.","64 Years",{"count":103,"type":21},20,[24],"The purpose of this study is to evaluate the safety, feasibility, and preliminary effectiveness of the ReWire system, which delivers vagus nerve stimulation (VNS) paired with lower limb rehabilitation to improve gait in individuals with mobility impairments resulting from chronic, incomplete spinal cord injury (SCI).",[107,28,108,109,110,111,112],"Spinal Cord Injury (SCI)","Reduced Physical Activity","Lower Limb Functions","Walking Impairment","Mobility Impairment","Functional Mobility",[114,115,116,117,118,119,120,28,121,122,123,124,125],"Vagus nerve stimulation (VNS)","Spinal cord injury (SCI)","Closed-loop vagus nerve stimulation (CLV)","ReWire System","Physical and rehabilitation therapy","XNerve Medical","Texas Biomedical Device Center (TxBDC)","Reduced physical activity","Lower limb functions","Walking impairment","Mobility impairment","Functional mobility","2026-07-23",{"date":128,"type":42},"2026-07-27",{"date":130,"type":21},"2026-09-30",{"date":132,"type":21},"2028-12",{"name":134,"class":49},"The University of Texas at Dallas",4,{"id":137,"slug":138,"hasResults":11,"nctId":139,"briefTitle":140,"officialTitle":141,"acronym":4,"eligibilityCriteria":142,"healthyVolunteers":57,"sex":16,"minAge":58,"maxAge":143,"enrollmentInfo":144,"targetDuration":4,"studyType":22,"phases":146,"briefSummary":147,"conditions":148,"keywords":150,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":155,"lastUpdatePostDateStruct":156,"startDateStruct":158,"completionDateStruct":160,"leadSponsor":162,"locationsCount":50},"100646699","effects-of-basic-body-awareness-therapy-on-gait-and-plantar-pressure-in-healthy-young-adults-100646699","NCT07688785","Effects of Basic Body Awareness Therapy on Gait and Plantar Pressure in Healthy Young Adults","Effects of Basic Body Awareness Therapy on Spatiotemporal Gait Characteristics and Plantar Pressure Distribution in Healthy Young Adults","Inclusion Criteria:\n\n* Aged 18 to 25 years\n* Able to walk independently\n* No history of lower-extremity, spine, or balance-affecting trauma and\u002For surgery within the last 6 months\n* Not receiving regular Basic Body Awareness Therapy\n* Provides written informed consent\n\nExclusion Criteria:\n\n* History of neurological, vestibular, or rheumatological disease\n* Acute musculoskeletal injury\n* Serious visual or hearing impairment\n* Pain, deformity, or assistive device use that may affect walking performance\n* Participation in a physiotherapy program and\u002For regular exercise program within the last 6 months\n* Any condition preventing regular participation in assessment or therapy sessions","25 Years",{"count":145,"type":21},33,[24],"This interventional study will evaluate the effects of Basic Body Awareness Therapy (BBAT) on gait and plantar pressure outcomes in healthy young adults. Participants aged 18 to 25 years will receive a 12-week BBAT program delivered twice weekly by a physiotherapist trained in BBAT. Outcomes will be assessed at baseline, after the 12-week intervention, and at 3-month follow-up. The primary aim is to determine changes in gait speed and other spatiotemporal gait parameters during the 10-meter walk test. Secondary aims are to examine changes in static and dynamic plantar load distribution, right-left load sharing, and regional plantar pressure parameters. The study hypothesizes that BBAT will improve gait speed, reduce right-left differences in spatiotemporal gait parameters, improve bilateral load distribution during static stance and walking, and maintain these gains at 3-month follow-up.",[28,149],"Body Awareness",[151,152,153,154],"Basic body awareness therapy","healthy young adult","Gait Analysis","plantar pressure","2026-07-14",{"date":157,"type":42},"2026-07-15",{"date":159,"type":42},"2026-06-29",{"date":161,"type":21},"2027-01-04",{"name":163,"class":49},"Hacettepe University",{"id":165,"slug":166,"hasResults":11,"nctId":167,"briefTitle":168,"officialTitle":168,"acronym":4,"eligibilityCriteria":169,"healthyVolunteers":11,"sex":16,"minAge":170,"maxAge":171,"enrollmentInfo":172,"targetDuration":4,"studyType":22,"phases":174,"briefSummary":175,"conditions":176,"keywords":183,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":186,"lastUpdatePostDateStruct":187,"startDateStruct":189,"completionDateStruct":191,"leadSponsor":193,"locationsCount":50},"100504462","gait-rehabilitation-to-treat-fastoa-100504462","NCT05848622","Gait Rehabilitation to Treat FastOA","Inclusion Criteria:\n\n* Have completed all other formal physical therapy\n* Are between the ages of 16 and 35\n* Underwent an anterior cruciate ligament reconstruction (ACLR) between 6 and 60 months prior to enrollment\n* Demonstrate underloading during gait (vGRF- impact peak \\\u003C1.12 x BW)\n\nExclusion Criteria:\n\n* A multiple ligament surgery (i.e., PCL)\n* A lower extremity fracture (i.e., displaced tibial plateau fracture)\n* Knee osteoarthritis","16 Years","35 Years",{"count":173,"type":21},70,[24],"The purpose of this study is to determine the effects of real-time gait biofeedback delivered over a 6-week period on early markers of FastOA and conduct 6-week and 6-month follow-up assessments in anterior cruciate ligament reconstructed patients.",[177,178,179,180,181,182,28],"Anterior Cruciate Ligament Injuries","Post-traumatic Osteoarthritis","Knee Osteoarthritis","Osteo Arthritis Knee","Knee Injuries","Cartilage, Articular",[184,185],"Biofeedback","FastOA","2026-06-24",{"date":188,"type":42},"2026-06-25",{"date":190,"type":42},"2023-06-13",{"date":192,"type":21},"2027-06",{"name":194,"class":49},"University of North Carolina, Chapel Hill",{"id":196,"slug":197,"hasResults":11,"nctId":198,"briefTitle":199,"officialTitle":200,"acronym":201,"eligibilityCriteria":202,"healthyVolunteers":11,"sex":16,"minAge":203,"maxAge":204,"enrollmentInfo":205,"targetDuration":4,"studyType":22,"phases":206,"briefSummary":207,"conditions":208,"keywords":210,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":217,"lastUpdatePostDateStruct":218,"startDateStruct":220,"completionDateStruct":222,"leadSponsor":224,"locationsCount":50},"100640123","music-effect-on-concentration-and-gait-in-cerebral-palsy-children-during-physical-therapy-sessions-100640123","NCT07625878","Music Effect on Concentration and Gait in Cerebral Palsy Children During Physical Therapy Sessions","Effect of Physiotherapy With Auditory Cueing on Concentration and Gait in Children With Spastic Cerebral Palsy","NMT\\CP","Inclusion Criteria:\n\n* • The children age ranged from 5 to 7 years old (early childhood).\n\n  * Spasticity degree ranges from 1 to 1+ as measured by the Modified Ashworth Scale\n  * Children with lack of concentration according to MARS (Moss Attention Rating Scale)\n  * Children can stand alone and walk.\n\nExclusion Criteria:\n\n* • Children with deafness.","5 Years","7 Years",{"count":61,"type":21},[24],"* To investigate the effect of music therapy as an additional intervention with physical therapy on concentration in children with spastic CP.\n* To investigate the effect of music therapy as an additional intervention with physical therapy on gait parameters for the children with spastic CP.",[209,28],"Attention",[211,212,213,70,214,215,216],"sensory motor rehabilitation","music","auditory cue","attention","CP","children","2026-06-03",{"date":219,"type":42},"2026-06-04",{"date":221,"type":21},"2026-05-20",{"date":223,"type":21},"2027-05-15",{"name":48,"class":49},{"id":226,"slug":227,"hasResults":11,"nctId":228,"briefTitle":229,"officialTitle":230,"acronym":231,"eligibilityCriteria":232,"healthyVolunteers":11,"sex":16,"minAge":58,"maxAge":4,"enrollmentInfo":233,"targetDuration":4,"studyType":22,"phases":234,"briefSummary":235,"conditions":236,"keywords":241,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":243,"lastUpdatePostDateStruct":244,"startDateStruct":245,"completionDateStruct":247,"leadSponsor":249,"locationsCount":50},"100638614","the-effects-of-high-intensity-interval-training-on-gait-balance-and-cognitive-functions-in-individuals-with-multiple-sclerosis-100638614","NCT07578740","The Effects of High-Intensity Interval Training on Gait, Balance, and Cognitive Functions in Individuals With Multiple Sclerosis","Investigating the Effects of High-Intensity Interval Training on Gait, Balance, and Cognition in Individuals With Multiple Sclerosis","HIIT-MS","Inclusion Criteria:\n\n* Diagnosed with Multiple Sclerosis by a neurologist (Hacettepe University Hospitals, Neurology Outpatient Clinic)\n* Age 18 years and older\n* EDSS score between 0 and 4\n* Score of 24 or above on the Standardized Mini Mental State Examination\n* No relapse in the past 3 months\n* Medically stable for at least 6 months\n\nExclusion Criteria:\n\n• Any additional cardiopulmonary, neurological, or systemic disease other than MS",{"count":61,"type":21},[24],"This study aims to comparatively investigate the effects of low-volume High-Intensity Interval Training (HIIT) versus Moderate-Intensity Continuous Training (MICT) on gait, balance, cognitive functions, and neurovascular biomarkers (BDNF, VEGF) in individuals with Multiple Sclerosis (MS). This randomized controlled trial will be conducted at Hacettepe University, Faculty of Physical Therapy and Rehabilitation.",[237,238,28,27,239,240],"Multiple Sclerosis","High-intensity Interval Training","Cognition","Biomarkers",[242],"Multiple Sclerosis, High-Intensity Interval Training, HIIT, Gait, Balance, Cognition, BDNF, VEGF, Randomized Controlled Trial","2026-05-18",{"date":221,"type":42},{"date":246,"type":21},"2026-07",{"date":248,"type":21},"2028-06",{"name":163,"class":49},{"id":251,"slug":252,"hasResults":11,"nctId":253,"briefTitle":254,"officialTitle":255,"acronym":4,"eligibilityCriteria":256,"healthyVolunteers":57,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":257,"targetDuration":4,"studyType":259,"phases":4,"briefSummary":260,"conditions":261,"keywords":4,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":264,"lastUpdatePostDateStruct":265,"startDateStruct":267,"completionDateStruct":269,"leadSponsor":271,"locationsCount":50},"100639707","gait-and-cognitive-function-in-relation-to-foot-arch-structure-in-older-adults-100639707","NCT07582367","Gait and Cognitive Function in Relation to Foot Arch Structure in Older Adults","Relationship Between Foot Arch Structure, Spatiotemporal Gait Parameters, and Cognitive Function in Older Adults","Inclusion Criteria:\n\n* Aged 65 years or older\n* Able to walk independently for at least 10 meters without assistive devices\n* Able to understand study procedures and provide informed consent\n* Having sufficient cognitive and physical capacity to comply with the assessment protocol\n\nExclusion Criteria:\n\n* Diagnosed neurological disorders affecting gait and motor control (e.g., stroke, Parkinson's disease, multiple sclerosis)\n* Diagnosed dementia or Alzheimer's disease, or Mini-Mental State Examination (MMSE) score below 24\n* Severe visual or hearing impairment that cannot be corrected and may affect reaction time testing\n* History of major lower extremity or spinal surgery within the last 6 months Severe musculoskeletal conditions affecting gait (e.g., advanced osteoarthritis, severe pain, active inflammation, open wounds, or recent fractures in the lower extremity)\n* Presence of severe balance disorders (e.g., vertigo)",{"count":258,"type":21},50,"OBSERVATIONAL","This study aims to investigate the relationship between foot arch structure and spatiotemporal gait parameters and cognitive function in older adults. Foot arch integrity will be assessed using the Navicular Drop Test, and gait performance will be evaluated using the 10-Meter Walk Test. Cognitive-motor interaction will be examined through lower extremity reaction time using a light-based system. The study is designed as an observational cross-sectional analysis.",[28,262,263],"Foot Biomechanics","Cognitive Function","2026-05-07",{"date":266,"type":42},"2026-05-12",{"date":268,"type":42},"2026-04-15",{"date":270,"type":21},"2026-11-08",{"name":272,"class":49},"Balikesir University",{"id":274,"slug":275,"hasResults":11,"nctId":276,"briefTitle":277,"officialTitle":278,"acronym":279,"eligibilityCriteria":280,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":281,"targetDuration":4,"studyType":259,"phases":4,"briefSummary":283,"conditions":284,"keywords":4,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":264,"lastUpdatePostDateStruct":286,"startDateStruct":288,"completionDateStruct":290,"leadSponsor":292,"locationsCount":50},"100639177","figure-of-8-walk-test-in-individuals-with-motoric-cognitive-risk-syndrome-100639177","NCT07586553","Figure-of-8 Walk Test in Individuals With Motoric Cognitive Risk Syndrome","Validity and Reliability of the Figure-of-8 Walk Test (8FWT) in Individuals With Motoric Cognitive Risk Syndrome","8FWT-MCR","Inclusion Criteria:\n\nAged 65 years or older Presence of subjective cognitive complaints Gait speed ≤ 0.8 m\u002Fs (4-meter walk test) Able to walk independently without assistive devices No clinical diagnosis of dementia Able to understand and follow test instructions\n\nExclusion Criteria:\n\nMini-Mental State Examination (MMSE) score \\\u003C 24 Neurological diseases affecting gait (e.g., stroke, Parkinson's disease, multiple sclerosis) Severe musculoskeletal conditions affecting walking Lower extremity surgery within the last 6 months Severe visual or hearing impairment that interferes with testing Dependence on assistive walking devices",{"count":282,"type":21},52,"This observational study aims to investigate the validity and reliability of the Figure-of-8 Walk Test (8FWT) in individuals with Motoric Cognitive Risk Syndrome (MCRS). The study will evaluate test-retest reliability, measurement error (SEM, MDC), and construct validity by examining the relationship between 8FWT performance and functional mobility measures. The findings are expected to provide evidence for the clinical applicability of 8FWT in assessing dynamic balance, gait performance, and cognitive-motor interaction in older adults.",[285,28,27],"Motoric Cognitive Risk Syndrome",{"date":287,"type":42},"2026-05-14",{"date":289,"type":42},"2026-04-07",{"date":291,"type":21},"2026-07-08",{"name":272,"class":49},{"id":294,"slug":295,"hasResults":11,"nctId":296,"briefTitle":297,"officialTitle":298,"acronym":4,"eligibilityCriteria":299,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":300,"targetDuration":4,"studyType":259,"phases":4,"briefSummary":302,"conditions":303,"keywords":4,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":305,"lastUpdatePostDateStruct":306,"startDateStruct":307,"completionDateStruct":308,"leadSponsor":309,"locationsCount":50},"100636998","dual-task-effects-on-gait-and-balance-in-mcrs-100636998","NCT07572968","Dual-Task Effects on Gait and Balance in MCRS","Effects of Cognitive Load on Gait and Balance Performance in Individuals With Motoric Cognitive Risk Syndrome: A Dual-Task Analysis","Inclusion Criteria:\n\nAge ≥ 65 years Subjective cognitive complaints Slow gait speed No dementia diagnosis\n\nExclusion Criteria:\n\nSevere visual\u002Fhearing impairment Neurological diseases (stroke, Parkinson) Acute orthopedic conditions affecting walking",{"count":301,"type":21},35,"This study aims to investigate the effects of cognitive load on gait and balance performance in individuals with Motoric Cognitive Risk Syndrome (MCRS). Participants will perform Timed Up and Go (TUG) and tandem walking tests under single-task and dual-task conditions. The study evaluates cognitive-motor interference and dual-task cost to better understand early markers of cognitive decline and fall risk.",[285,304,28,27],"Dual-Task Performance","2026-05-01",{"date":264,"type":42},{"date":268,"type":42},{"date":157,"type":21},{"name":272,"class":49},{"id":311,"slug":312,"hasResults":11,"nctId":313,"briefTitle":314,"officialTitle":314,"acronym":315,"eligibilityCriteria":316,"healthyVolunteers":57,"sex":16,"minAge":58,"maxAge":317,"enrollmentInfo":318,"targetDuration":4,"studyType":22,"phases":320,"briefSummary":321,"conditions":322,"keywords":4,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":327,"lastUpdatePostDateStruct":328,"startDateStruct":330,"completionDateStruct":332,"leadSponsor":334,"locationsCount":50},"100602772","effects-of-treadmill-based-gait-training-in-patients-with-stroke-100602772","NCT07127861","Effects of Treadmill-Based Gait Training in Patients With Stroke","TreadmillACV","Inclusion Criteria:\n\n* Aged between 18 and 80 years\n* History of stroke at least six months prior\n* Presence of hemiplegia or hemiparesis\n* Ability to walk independently or with assistive devices\n\nExclusion Criteria:\n\n* Cognitive impairments interfering with the understanding of treatment procedures\n* Inability to get on and maintain position on the treadmill\n* Severe heart failure\n* Active inflammatory or infectious conditions at the time of evaluation\n* Attendance below 80% of scheduled sessions","80 Years",{"count":319,"type":21},24,[24],"Hemiplegia is one of the most common sequelae after stroke. Most patients develop thermal asymmetry between the affected and contralateral sides of the body, as well as an asymmetric gait pattern characterized by differences in the duration of gait cycle phases, step length, cadence, and weight distribution between limbs. These patterns result in reduced aerobic capacity, endurance, energy efficiency, and walking speed, negatively impacting the patient's functional abilities.\n\nThere are different methodologies for the treatment gait impairments. Among them, treadmill training has been investigated as an effective therapeutic approach to post-stroke rehabilitation.\n\nTreadmill gait training may reduce asymmetry between hemibodies in hemiplegic patients.\n\nFor this reason, our aim is to describe the effects of treadmill training on gait, focusing on its impact on thermal asymmetry, walking speed, aerobic endurance, and the biomechanical and kinematic characteristics of gait.\n\nPatients with hemiplegia will undergo treadmill-based gait training to evaluate its influence on the recovery of this sequel of stroke.",[28,323,324,325,326,153],"Thermography","Walking Speed, Mesh id D000072797","Endurance","Step Time and Length","2026-03-25",{"date":329,"type":42},"2026-03-31",{"date":331,"type":42},"2025-09-14",{"date":333,"type":21},"2026-03",{"name":335,"class":49},"University of Salamanca",{"id":337,"slug":338,"hasResults":11,"nctId":339,"briefTitle":340,"officialTitle":341,"acronym":4,"eligibilityCriteria":342,"healthyVolunteers":11,"sex":16,"minAge":204,"maxAge":343,"enrollmentInfo":344,"targetDuration":4,"studyType":22,"phases":346,"briefSummary":347,"conditions":348,"keywords":349,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":358,"lastUpdatePostDateStruct":359,"startDateStruct":361,"completionDateStruct":363,"leadSponsor":365,"locationsCount":367},"100546828","dual-tasking-effect-on-gait-in-children-with-developmental-coordination-disorder-100546828","NCT06400043","Dual-tasking Effect on Gait in Children With Developmental Coordination Disorder","The Influence of an Interceptive Task on Gait in Children With Developmental Coordination Disorder Compared to Typically Developing Children","Inclusion Criteria:\n\n* They have an official DCD diagnosis;\n* Are aged between 7 and 17 years old;\n* Can walk at least 15 minutes consecutively;\n* Have good or corrected vision.\n\nExclusion Criteria:\n\n* They suffer from a neurological disorder;\n* Take medications that affect gait and balance;\n* Have undergone surgical procedures on the lower limbs in the past;\n* Experience pain in their lower limbs or back at the time of testing.","17 Years",{"count":345,"type":21},23,[24],"The aim of the study is to collect data in children with developmental coordination disorder (DCD) aged between 7 and 17 years for analyses of the gait pattern while walking at the Gait Real-time Analysis Interactive Lab (GRAIL) at the university hospital of Ghent.\n\nChildren with DCD will be asked to take a motor test (M-ABC-2) as well as walk on the treadmill during a single session of approximately 3 hours.\n\nThe following data will be collected on the GRAIL while subjects walk at different gait speeds: 3D kinematics, kinetics, and EMG.\n\nAdditionally, 3D kinematics, kinetics, and EMG data will be collected when performing either a cognitive (Stroop Color and Word Test) or motor (requiring arm swing) dual-task while walking at comfortable walking speed..",[28],[350,351,352,353,354,355,356,357],"Gait analysis","Dual-tasking","EMG","Kinematics","Kinetics","Selective motor control","Developmental Coordination Disorder","DCD","2026-03-19",{"date":360,"type":42},"2026-03-20",{"date":362,"type":42},"2024-07-12",{"date":364,"type":21},"2026-08-31",{"name":366,"class":49},"University Ghent",2,{"id":369,"slug":370,"hasResults":11,"nctId":371,"briefTitle":372,"officialTitle":373,"acronym":4,"eligibilityCriteria":374,"healthyVolunteers":11,"sex":16,"minAge":58,"maxAge":17,"enrollmentInfo":375,"targetDuration":4,"studyType":22,"phases":376,"briefSummary":377,"conditions":378,"keywords":381,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":387,"lastUpdatePostDateStruct":388,"startDateStruct":390,"completionDateStruct":392,"leadSponsor":394,"locationsCount":50},"100606393","innovative-approaches-to-enhance-balance-and-neuroplasticity-in-multiple-sclerosis-100606393","NCT07174973","Innovative Approaches to Enhance Balance and Neuroplasticity in Multiple Sclerosis","Innovative Approaches to Enhance Balance and Neuroplasticity in Multiple Sclerosis: Evaluating the Combined Effects of Transcutaneous Spinal Cord Stimulation, Functional Electrical Stimulation, and Visual Feedback Balance Training","Participants will be eligible if they meet the following conditions:\n\n* Confirmed diagnosis of Multiple Sclerosis (MS) according to the revised McDonald criteria\n* Age ≤ 65 years\n* Ability to walk at least 100 meters, with or without an assistive device, and without requiring rest\n* Self-reported perception of impaired balance during standing or walking in daily activities\n\nExclusion Criteria:\n\n* Participants will be excluded if they present with any of the following:\n* Uncorrected visual problems\n* Cognitive impairment affecting comprehension of instructions or completion of self-administered outcome measures\n* Ongoing MS exacerbation or paroxysmal vertigo\n* Concurrent neurological or orthopedic conditions affecting balance\n* Recent participation in rehabilitation therapies (physical therapy, occupational therapy, or vestibular therapy) within one month prior to recruitment\n* Planned or recent injection of botulinum toxin to the legs during the intervention period\n* Peripheral nerve damage affecting the legs\n* Contraindications to electrical stimulation, including:implanted electronic device, active cancer or radiation treatment within the past 6 months, uncontrolled epilepsy, skin rash or open wound at electrode site, pregnancy, active deep vein thrombosis",{"count":319,"type":21},[24],"This study will evaluate the effects of combining balance training with electrical stimulation techniques in individuals with Multiple Sclerosis (MS). MS commonly impairs leg strength, coordination, and balance, increasing the risk of falls and reducing independence. The interventions include:Balance training only, Balance training with Functional Electrical Stimulation (FES), and Balance training with FES and Transcutaneous Spinal Cord Stimulation (TSCS). FES delivers small electrical pulses to leg muscles, while TSCS delivers electrical signals through the skin to stimulate the spinal cord and enhance motor control.\n\nThe study will enroll up to 24 participants over a 3-year period. This trial is funded by MS Canada. Participants will be randomly assigned to one of three groups: (1) balance training only, (2) balance training with FES, or (3) balance training with FES and TSCS. All participants will complete 12 supervised training sessions over 6 weeks. During each session, participants will engage in interactive balance games while standing in a safety harness.Outcome assessments will be conducted at three time points: baseline (prior to training), post-intervention (after 6 weeks), and follow-up (8 weeks after training).\n\nAssessments will include:\n\n* Clinical tests of mobility and balance (Timed Up and Go:TUG, 10-Meter Walk Test:10MWT, Berg Balance Scale:BBS)\n* Computerized balance testing using a force plate\n* Questionnaires on walking ability, fear of falling, and balance confidence\n* Neurophysiological measures of brain-spinal cord-muscle communication before and after training",[237,379,380,28],"Mobility Limitation","Balance; Distorted",[382,383,384,385,386],"balance","neuromodulation","neuroplasticity","multiple sclerosis","mobility","2026-03-12",{"date":389,"type":42},"2026-03-16",{"date":391,"type":42},"2025-12-30",{"date":393,"type":21},"2028-12-30",{"name":395,"class":49},"University Health Network, Toronto",{"id":397,"slug":398,"hasResults":11,"nctId":399,"briefTitle":400,"officialTitle":401,"acronym":4,"eligibilityCriteria":402,"healthyVolunteers":11,"sex":16,"minAge":58,"maxAge":18,"enrollmentInfo":403,"targetDuration":4,"studyType":22,"phases":405,"briefSummary":406,"conditions":407,"keywords":408,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":411,"lastUpdatePostDateStruct":412,"startDateStruct":414,"completionDateStruct":416,"leadSponsor":418,"locationsCount":50},"100590262","implant-for-walking-after-incomplete-sci-100590262","NCT06965127","Implant for Walking After Incomplete SCI","Enhancing Walking and Independence After Incomplete SCI With a Fully Implanted Neuroprosthesis","Inclusion Criteria:\n\n* Between the ages of 18-75\n* Non-ventilator dependent paralysis resulting from injuries such as: cervical\u002Fthoracic spinal cord injuries affecting the trunk and\u002For lower limbs\n* Impairment classification of AIS B, C, or D (preservation of sensation and\u002For some motor function) with weakness in trunk and\u002For lower extremity muscles\n* Unable to walk faster than 0.8m\u002Fs during a 10m walk test\n* Gait deviation such as reduced peak hip, knee, and\u002For ankle range of motion during stance or swing phases due to motor impairment\n* Time post injury greater than six months\n* Innervated and excitable lower extremity and trunk musculature\n* Adequate social support and stability\n* Willingness to comply with follow-up procedures\n* Appropriate body habitus (height and weight within acceptable limits as determined by study physician)\n* Neurologically stable as determined by a physician\n\nExclusion Criteria:\n\n* Significant fracture risk or history of spontaneous fractures\n* History of heterotopic ossification at the hip, knee, or ankle\n* Non-English speaking\n* Insufficient upper extremity function to use an assistive device (e.g. walker or cane)\n* Females who are pregnant\n* Current pressure injury that would be exacerbated by study activities\n* Uncontrolled spasticity that would interfere with study activities\n* Significant range of motion limitations that would compromise study activities\n* History of vestibular dysfunction, balance problems, or spontaneous falls\n* Disorder or condition that require MRI monitoring\n* Acute and\u002For untreated orthopedic issues that would prevent weight bearing or exercising implanted muscles such as a dislocation or fracture\n* Acute and\u002For chronic medical problems left untreated or not controlled that would increase risk by using stimulation such as cardiac abnormalities, immunological\u002Fpulmonary\u002Frenal\u002Fcirculatory compromise\n* Uncontrolled diabetes or hypertension\n* Presence of a demand pacemaker, cardiac defibrillator, or neuroprosthesis system with components in the legs\n* Any other medical or psychological condition that would be a contraindication\n\nImplant eligibility criteria\n\n• In addition to all of the above, the participant must be able to fully support their body weight in standing with an assistive device prior to implantation.",{"count":404,"type":21},5,[24],"This is a device study that will evaluate the effect of an implanted stimulator on improving walking in people with incomplete spinal cord injury. There are two phases in the study: 1) Screening - this phase determines if the individual is a good candidate to receive an implanted system, 2) Implantation, controller development, and evaluation - this phase includes implanting the device and setting the individual up for system use, creating controllers for walking, and evaluating the effect of the device over a couple years.",[107,28],[409,410],"neuroprosthesis","implanted device","2025-11-20",{"date":413,"type":42},"2025-11-26",{"date":415,"type":42},"2025-08-27",{"date":417,"type":21},"2031-08",{"name":419,"class":420},"Louis Stokes VA Medical Center","FED",{"id":422,"slug":423,"hasResults":11,"nctId":424,"briefTitle":425,"officialTitle":426,"acronym":4,"eligibilityCriteria":427,"healthyVolunteers":57,"sex":16,"minAge":58,"maxAge":17,"enrollmentInfo":428,"targetDuration":4,"studyType":22,"phases":429,"briefSummary":430,"conditions":431,"keywords":432,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":436,"lastUpdatePostDateStruct":437,"startDateStruct":439,"completionDateStruct":441,"leadSponsor":443,"locationsCount":50},"100549142","ab-gait-estim-neurophysiology-100549142","NCT06430164","AB Gait Estim Neurophysiology","Effects of Gait Training Strategies and Noninvasive Stimulation on Neurophysiology and Walking Performance in Able-Bodied Adults- A Preliminary Study","Inclusion Criteria:\n\n* 18-65 years\n* Able-bodied (healthy without any physical disability, neurological, orthopedic, or other medical disorder affecting walking or study protocol participation)\n* Ability to walk \\>10m overground and for 1 minute on a treadmill\n* Ability to follow 3-stage commands and provide informed consent.\n\nExclusion Criteria:\n\n* Self-reported history or evidence of orthopedic or physical disability\n* History or evidence of neurological pathology\n* Pregnancy (female)\n* Uncontrolled hypertension\n* Cardiac pacemaker or other implanted electronic system\n* Presence of skin conditions preventing electrical stimulation setup\n* Impaired sensation in the left upper limb.\n* Bruises or cuts at the stimulation electrode placement site\n* Concurrent enrollment in rehabilitation or another investigational study.\n* History or evidence of orthopedic or physical disability interfering with study procedures\n* History or evidence of neurological pathology or disorder\n* Severe uncontrolled medical problems (e.g., hypertension, cardiovascular disease, rheumatoid arthritis, active cancer or renal disease, epilepsy) that may interfere with study procedures\n* Contraindications to TMS such as metal implants, medications that can increase cortical excitability, unexplained dizziness in the past 6 months",{"count":258,"type":21},[24],"This study is being done to answer the question: What are the effects of electrical stimulation and stepping practice on connections between the brain and muscles? The long-term goal of this project is to develop novel, effective, and personalized rehabilitation protocols founded on an understanding of neurobiological mechanisms that combine electrical stimulation with gait training to improve gait performance in older adults and stroke survivors.\n\nThe rationale of this project is to explore and generate preliminary data regarding how electrical stimulation-based strategies modulate cortical and spinal circuits in able-bodied individuals.\n\nThe researchers will evaluate the effects of short treadmill walking bouts or single gait training sessions with and without electrical stimulation on somatosensory, spinal-reflex, corticospinal circuit neurophysiology, and\u002For gait performance.\n\nThe study will provide important preliminary and normative data that can explain how brain circuits change with stimulation or stepping practice and inform future rehabilitation studies on patients. The study population is able-bodied individuals.",[28],[433,434,435],"Corticospinal excitability","Non-invasive stimulation","Functional electrical stimulation (FES)","2025-07-24",{"date":438,"type":42},"2025-07-28",{"date":440,"type":42},"2024-02-12",{"date":442,"type":21},"2026-12",{"name":444,"class":49},"Emory University",{"id":446,"slug":447,"hasResults":11,"nctId":448,"briefTitle":449,"officialTitle":449,"acronym":4,"eligibilityCriteria":450,"healthyVolunteers":57,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":451,"targetDuration":4,"studyType":22,"phases":453,"briefSummary":454,"conditions":455,"keywords":457,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":460,"lastUpdatePostDateStruct":461,"startDateStruct":463,"completionDateStruct":465,"leadSponsor":467,"locationsCount":4},"100599505","attentional-focus-training-on-visuomotor-control-in-older-adults-100599505","NCT07085364","Attentional Focus Training on Visuomotor Control in Older Adults","Inclusion Criteria:\n\n* aged 65 or above\n* able to walk independently indoor for at least 40 metres\n* static visual acuity score 20\u002F40 or above\n* scoring 22\u002F30 or above in the Montreal Cognitive Assessment Hong Kong version\n* without any history of untreated major neurological, vestibular or musculoskeletal deficits (e.g., stroke or Parkinson's disease)\n* without any unstable medical condition that can compromise safety during the experiment\n* scoring less than 24\u002F28 in the Tinetti Balance Assessment Tool or scoring 50\u002F56 or below in the Berg Balance Scale\n\nExclusion Criteria:\n\n* none",{"count":452,"type":21},16,[24],"This study will be a pilot randomized controlled trial, to investigate the effectiveness of an external focus training on visuomotor performance while comparing with an active control group.",[28,209,456],"Older Adults",[458,70,459,37],"attentional focus","visual search","2025-07-17",{"date":462,"type":42},"2025-07-25",{"date":464,"type":21},"2025-08-01",{"date":466,"type":21},"2026-05-31",{"name":468,"class":49},"The Hong Kong Polytechnic University",{"id":470,"slug":471,"hasResults":11,"nctId":472,"briefTitle":473,"officialTitle":474,"acronym":4,"eligibilityCriteria":475,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":476,"targetDuration":4,"studyType":22,"phases":478,"briefSummary":479,"conditions":480,"keywords":483,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":485,"lastUpdatePostDateStruct":486,"startDateStruct":488,"completionDateStruct":490,"leadSponsor":491,"locationsCount":50},"100545864","feasibility-of-fabric-orthosis-for-knee-support-in-elderly-gait-improvement-100545864","NCT06387459","Feasibility of Fabric Orthosis for Knee Support in Elderly Gait Improvement","Safety and Feasibility of Knee Extensor Muscle-mimicking, Fabric-type Orthosis on Gait in Geriatric Patients: Pilot Clinical Trial","Inclusion Criteria:\n\nEligibility for participation in the study requires that all the following criteria are met:\n\n1. Age: Participants must be 65 years of age or older.\n2. Comprehension and Compliance: Able to fully understand and comply with the instructions and study procedures.\n3. Mobility-Impacting Conditions: Must have at least one of the following conditions affecting mobility: (1)Sarcopenia:\n\n   * Muscle Strength: Handgrip strength of \\\u003C28 kg for men and \\\u003C18 kg for women.\n   * Muscle Function: Short Physical Performance Battery (SPPB) score of 8 or less.\n   * Muscle Mass: Bioelectrical impedance analysis (BIA) showing muscle mass \\\u003C7.0 kg\u002Fm² for men and \\\u003C5.7 kg\u002Fm² for women. (2)Diabetes:\n   * Diagnosed distal symmetric polyneuropathy.\n   * Sensory impairments in toes or feet. (3)Knee Osteoarthritis:\n   * Kellgren-Lawrence grade ≥2.\n   * Persistent pain (≥3 months) with a severity of at least 3 on the Numerical Rating Scale (NRS).\n\nExclusion Criteria:\n\nIndividuals meeting any of the following criteria will be excluded from study participation:\n\n1. Inability to Consent: Unable to provide informed consent or not willing to participate in the study procedures.\n2. Severe Sensory or Motion Limitations: Including severe visual or vestibular impairments that could increase the risk of falling.\n3. Communication Barriers: Significant hearing, speech, or language problems that would hinder communication with study personnel.\n4. Independent Walking Inability: Cannot walk independently without the aid of a walking device.\n5. Other Significant Diseases or Conditions:\n\n   * Neurological disorders that affect walking ability (e.g., stroke, Parkinson's disease).\n   * Orthopedic or musculoskeletal conditions severely affecting lower limb function.\n   * Severe cardiovascular conditions including uncontrolled hypertension or heart failure.\n   * Respiratory diseases requiring regular oxygen therapy.\n   * Active cancer treatment or cancer treatment within the past 3 years (except basal cell carcinoma or localized prostate cancer).\n   * Severe psychiatric disorders like schizophrenia or bipolar disorder.\n6. Other Exclusionary Factors:\n\n   * Past severe orthopedic surgeries on lower limbs which might affect gait and mobility.\n   * Severe back pain or any other condition affecting mobility not already listed.",{"count":477,"type":21},30,[24],"This pilot clinical trial assesses the safety and feasibility of a novel fabric-type orthosis designed to mimic the knee extensor muscles and improve gait in elderly patients with mobility impairments due to conditions like sarcopenia, diabetes, or knee osteoarthritis. The study aims to test this orthosis in a real- world setting to see if it can enhance mobility and stability for elderly individuals, potentially reducing falls and improving quality of life. A total of 30 participants aged 65 and older will be recruited to use this orthosis across multiple sessions, where their gait will be analyzed under various conditions to measure the device's impact on walking speed, stability, and muscle activation.",[28,481,482],"Fall","Orthotic Devices",[484],"Geriatric patient","2025-06-08",{"date":487,"type":42},"2025-06-11",{"date":489,"type":42},"2024-07-31",{"date":287,"type":21},{"name":492,"class":49},"Seoul National University Hospital",{"id":494,"slug":495,"hasResults":11,"nctId":496,"briefTitle":497,"officialTitle":498,"acronym":4,"eligibilityCriteria":499,"healthyVolunteers":11,"sex":16,"minAge":18,"maxAge":4,"enrollmentInfo":500,"targetDuration":4,"studyType":22,"phases":501,"briefSummary":502,"conditions":503,"keywords":506,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":512,"lastUpdatePostDateStruct":513,"startDateStruct":515,"completionDateStruct":517,"leadSponsor":519,"locationsCount":50},"100575609","feasibility-of-high-intensity-functional-exercise-with-simultaneous-cognitive-challenge-for-older-people-with-falls-risk-100575609","NCT06774508","Feasibility of High-intensity Functional Exercise with Simultaneous Cognitive Challenge for Older People with Falls Risk","The Feasibility of a High-intensity Functional Exercise Program with Simultaneous Cognitive Challenge to Improve Physical and Cognitive Function in Older People with Intermediate Risk for Falls: a Randomized Controlled Pilot Trial","Inclusion Criteria:\n\n* aged 75 years or older\n* moderate risk of falling (feeling unsteady or afraid of falling, or having fallen in the past year, with a self-selected gait speed ≤0,8 m\u002Fs or TUG \\>15 s without walking aid)\n* can walk independently indoors, without a walking aid\n* can walk 500m independently outdoors, with or without a walking aid\n\nExclusion Criteria:\n\n* a high fall risk (≥2 falls in the past year, serious injury e.g. hip fracture from a fall in the past year requiring medical care, or inability to get up from the floor after a fall)\n* Mini-Mental State Examination (MMSE) score \\\u003C24 or dementia diagnosis\n* a medical condition that may affect participation in high-intensity gait, balance, and leg strength exercise, or other movement-related conditions affecting exercise or tests (e.g., pain, dizziness, visual or hearing impairment)",{"count":145,"type":21},[24],"This study aims to evaluate the feasibility of a high-intensity functional exercise program with simultaneous cognitive challenge (HIFE+cog) among older people at risk of falls. The evaluation design and intervention development will be assessed with the following specific aims:\n\n1. To investigate the acceptability and safety of the HIFE+cog program in older people at risk of falls, and the methods used in the study by evaluating recruitment, compliance with the intervention, severity of adverse events reported, and participant experiences.\n2. To measure key outcome variables, including completion rates, missing data, estimates, variances, and 95% confidence intervals for between-group differences.\n\nThe study is designed as a randomized controlled pilot trial. Eligible participants will be randomized to either the intervention group (HIFE+cog) or the active control group (HIFE) to partake in individually tailored exercise, supervised and progressed by a physiotherapist, two times per week for 3 months.",[504,505,28,239],"Accidental Falls","Postural Balance",[507,508,28,239,509,510,511],"Accidental falls","Postural balance","Exercise therapy","Resistance training","Aged","2025-02-21",{"date":514,"type":42},"2025-02-25",{"date":516,"type":42},"2025-02-17",{"date":518,"type":21},"2025-09-01",{"name":520,"class":49},"Umeå University",{"id":522,"slug":523,"hasResults":11,"nctId":524,"briefTitle":525,"officialTitle":525,"acronym":4,"eligibilityCriteria":526,"healthyVolunteers":11,"sex":16,"minAge":143,"maxAge":17,"enrollmentInfo":527,"targetDuration":4,"studyType":22,"phases":529,"briefSummary":530,"conditions":531,"keywords":535,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":543,"lastUpdatePostDateStruct":544,"startDateStruct":546,"completionDateStruct":548,"leadSponsor":550,"locationsCount":50},"100567930","effects-of-motor-relearning-program-versus-proprioceptive-neuromuscular-facilitation-on-balance-and-gait-in-stroke-100567930","NCT06674590","Effects of Motor Relearning Program Versus Proprioceptive Neuromuscular Facilitation on Balance and Gait in Stroke","Inclusion Criteria:\n\n* more than 6 month post stroke\n* both male and female\n* Can ambulate 25 feet\u002F10 meter (with or without assistive device).\n* Age between 25 to 65 years.\n* Grades for MAS (Grade 2 0r less )\u002Fstage of brunstrom approach (stage 4 or up )\n\nExclusion Criteria:\n\n* History of neurologic disease other than the chronic stroke.\n* Orthopedic disorder involving any joint of lower limbs that interfere with study.\n* Gross visuospatial deficits .\n* Unhealed fracture of lowerlimb .\n* Peripheral arterial occlusive disease.\n* Uncontrolled hypertension and diabetes",{"count":528,"type":21},26,[24],"A randomized control trial will be done on diagnosed stroke patients of chronic stage in DHQ Hospital Mirpur and FF Hospital Rawalpindi physical therapy Department.The purpose of the study is to determine Effects of Motor Relearning Program Versus Proprioceptive Neuromuscular Facilitation on Balance and Gait in Stroke .\n\nSubjects will complete Berg Balance Scale (BBS). 10-meter walk test for gait speed will be used for measuring walking speed in meters per second over a short distance, Timed-Up-And-Go (TUG) Test will be used for test of functional mobility and gait parameter. All these measures will be taken at baseline, then after 6 weeks of intervention. There will be 4 sessions per week. The control group will receive Group Motor relearning programe while the Study Group (B) will receive Proprioceptive Neuromuscular Facilitation(PNF)",[532,533,27,28,534],"Chronic Stroke","Proprioceptive Neuromuscular Facilitation","Gait Speed",[536,537,538,382,70,539,540,541,542],"Stroke","Motor relearning program","Proprioceptive neuromuscular facilitation","gait speed","stride length","cadence","cycle time","2024-11-04",{"date":545,"type":42},"2024-11-05",{"date":547,"type":42},"2024-06-20",{"date":549,"type":21},"2025-01-20",{"name":551,"class":49},"Foundation University Islamabad",{"id":553,"slug":554,"hasResults":11,"nctId":555,"briefTitle":556,"officialTitle":556,"acronym":4,"eligibilityCriteria":557,"healthyVolunteers":57,"sex":16,"minAge":558,"maxAge":4,"enrollmentInfo":559,"targetDuration":4,"studyType":22,"phases":560,"briefSummary":561,"conditions":562,"keywords":565,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":566,"lastUpdatePostDateStruct":567,"startDateStruct":568,"completionDateStruct":569,"leadSponsor":571,"locationsCount":50},"100567758","effects-of-non-immersive-virtual-reality-training-compared-to-otago-exercise-program-on-balance-and-spatiotemporal-gait-parameters-in-elderly-population-100567758","NCT06672354","Effects of Non-immersive Virtual Reality Training Compared to Otago Exercise Program on Balance and Spatiotemporal Gait Parameters in Elderly Population","Inclusion Criteria:\n\n* Age 55 years and above\n* Male and female both\n* Able to independently ambulate, without the assistance of a walking aid.\n* Participants that are able to maintain upright position with eyes open and eyes close for 10 seconds in standing position\n\nExclusion Criteria:\n\n* Wheel-chair bound elderly\n* Diagnosed with neurological disorder\n* Severe cognitive impairment (MMSE scoring of 17 or \\\u003C17)\n* Recent orthopedic trauma\n* Severe degenerative conditions","55 Years",{"count":61,"type":21},[24],"Falling is a serious concern for the growing elderly population due to age-related decline in physical function, leading to injuries, loss of independence, and a decline in overall well-being.\n\nThe Otago Exercise Program (OEP), for the elderly consists of lower limb strengthening and balance exercises, leading to better strength, balance, and reduced fear of falling.\n\nThe interactive and game-like nature of VR training can make it more engaging and motivating for older adults. It can provide challenging and engaging approach to exercise that can help to improve stability, enhance quality of life and reduce the risk of fall.",[563,27,28,564],"Elderly","Virtual Reality",[563,27,28,564],"2024-10-31",{"date":543,"type":42},{"date":547,"type":42},{"date":570,"type":21},"2024-12-20",{"name":551,"class":49},{"id":573,"slug":574,"hasResults":11,"nctId":575,"briefTitle":576,"officialTitle":576,"acronym":577,"eligibilityCriteria":578,"healthyVolunteers":11,"sex":579,"minAge":59,"maxAge":580,"enrollmentInfo":581,"targetDuration":4,"studyType":259,"phases":4,"briefSummary":583,"conditions":584,"keywords":4,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":587,"lastUpdatePostDateStruct":588,"startDateStruct":590,"completionDateStruct":591,"leadSponsor":593,"locationsCount":50},"100552115","analyzing-gait-parameters-among-women-with-and-without-stress-urinary-incontinence-100552115","NCT06468891","Analyzing Gait Parameters Among Women With and Without Stress Urinary Incontinence","GPWSUI","Inclusion Criteria:\n\n* Age between 40-60 years old.\n* Women with BMI ≥30.\n* Women are free from any other gynecological disorders or symptoms that may affect the results of the study.\n* All participants who will be enrolled in the study sign the informed consent form.\n* All participants will be of multiparas.\n* All participants will be diagnosed with a mild degree of stress urinary incontinence.\n\nExclusion Criteria:\n\n* Pregnancy\n* Neurological Disorders: such as Parkinson's disease , multiple sclerosis, or any neurological dysfunction that may affect the gait parameters\n* Musculoskeletal disorders: such as severe osteoarthritis or lower limb amputations\n* Significant cognitive impairment: or dementia\n* Previous pelvic surgery as pelvic organ prolapse repair or anti-incontinence procedures.\n* Other significant medical conditions that could affect gait include severe cardiovascular disease or severe respiratory conditions.\n* Walking pain.","FEMALE","60 Years",{"count":582,"type":21},124,"This study will contribute to the existing body of knowledge on stress urinary incontinence and its impact on gait. The findings may have implications for the development of targeted interventions and rehabilitation strategies to improve mobility and quality of life in women with stress urinary incontinence",[28,585,586],"Stress Urinary Incontinence","Women","2024-06-16",{"date":589,"type":42},"2024-06-21",{"date":587,"type":42},{"date":592,"type":21},"2024-08-30",{"name":48,"class":49},{"id":595,"slug":596,"hasResults":11,"nctId":597,"briefTitle":598,"officialTitle":599,"acronym":600,"eligibilityCriteria":601,"healthyVolunteers":57,"sex":16,"minAge":17,"maxAge":602,"enrollmentInfo":603,"targetDuration":4,"studyType":259,"phases":4,"briefSummary":605,"conditions":606,"keywords":608,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":611,"lastUpdatePostDateStruct":612,"startDateStruct":614,"completionDateStruct":616,"leadSponsor":618,"locationsCount":50},"100542650","gait-and-postural-balance-analysis-during-head-motion-perturbed-standing-and-walking-in-older-adults-100542650","NCT06345625","Gait and Postural Balance Analysis During Head-motion Perturbed Standing and Walking in Older Adults","Gait and Postural Balance Analysis During Head-motion Perturbed Standing and Walking in Older Adults - a Multisensory Approach by Use of Mixed-reality","BALANCAR","Inclusion Criteria:\n\n* Community dwelling\n* an age of 65 years or above\n\nExclusion Criteria:\n\n* age \\\u003C 65 years\n* medical history encompassing diagnosed vestibulopathy, orthostatic hypotension, peripheral neuropathy, limb amputation, neurological or neuromuscular disorders affecting balance, diagnosed neck disorders affecting sensorimotor control, blindness, deafness\n* a full-time walking aid is indispensable.","100 Years",{"count":604,"type":21},100,"The main aim of this study is to unravel the biomechanics of postural balance reactions during head-motion perturbed standing and walking in older adults who fall, while integrating the influence of frailty, sensory functioning and cognitive processing.",[511,607,505,28],"Accidental Fall",[37,609,610],"Sensorimotor integration","visual tracking while walking","2024-05-08",{"date":613,"type":42},"2024-05-09",{"date":615,"type":42},"2024-05-07",{"date":617,"type":21},"2028-01",{"name":619,"class":49},"Universiteit Antwerpen"]