[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"gaming-disorder\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:gaming-disorder":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,47,75,98,128,146],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100412387","phase-2-predicting-response-to-naltrexone-with-eye-tracking-in-gaming-disorder-100412387",false,"NCT04649892","Predicting Response to Naltrexone With Eye Tracking in Gaming Disorder","Predicting Response to Naltrexone With Eye Tracking in Videogame Disorder","Inclusion Criteria:\n\n* Patients will be evaluated initially in a clinical interview by a specialized psychiatrist and then by a second interviewer who will use a semi-structured interview to check the DSM-5 criteria for Video Game Disorder (VGD) modeled in the standard format of Schedules for clinical assessment in neuropsychiatry (SCID). Only a specific subgroup of VGD will be included in our sample, which will be called VGDa, a sample that represent a framework of behavioral dependence in essence. Patients in this sample must necessarily have the following symptoms: salience, withdrawal, relapse, conflict, mood modification and fissure. The criteria to delimit this subgroup are listed below:\n* Patients diagnosed with Internet Gaming Disorder according to DSM-5\n* Patients who have a score of 4 or higher on the following questions on the IGDS9-SF scale (Internet Gaming Disorder Scale 9 - Short Form):\n\nQuestion 1: Salience assessment. Question 2: Abstinence assessment. Question 4: Relapse assessment. Question 6: Conflict assessment. Question 8: Mood modification assessment.\n\n* Patients with craving according to the adaptation of the Gambling Follow-up Scale (GFS) described below.\n\nAn adaptation of the GFS scale, originally used to evaluate patients with Gambling Disorder, was made in order to allow the evaluation of the craving symptom in a patient with VGD. It will only be used the fourth question on this scale as follows.\n\n\"4) In the past 4 weeks, how was your desire to play?\n\n1. I felt an irresistible urge to play.\n2. I felt a strong desire to play, sometimes resistable, sometimes not.\n3. I felt a strong desire to play, but resistable most of the time.\n4. I felt a slight desire to play.\n5. I didn't feel like playing. \" It will considered that the patient has craving if he answers this question by selecting items 1, 2 or 3.\n\nPatients must meet the following criteria before randomization:\n\n* Have read and signed the informed consent form after the nature of the study has been fully explained and before carrying out any procedures related to the study;\n* Age between 18 and 60 years old, inclusive;\n* Female patients must be:\n\n  1. In post-menopause for at least one year, or;\n  2. Being surgically incapable of becoming pregnant (undergoing bilateral hysterectomy or oophorectomy or tubal ligation or otherwise being unable to become pregnant), or;\n  3. Be practicing an acceptable method of birth control (defined as: hormonal contraceptives, spermicide plus barrier, a single vasectomized partner and \u002F or intrauterine device).\n  4. If a patient with the potential to become pregnant is practicing an acceptable method of birth control (as mentioned above), she must have a negative urine pregnancy test at the enrollment stage, as well as, at baseline, before receiving the study drug.\n\nExclusion Criteria:\n\n* \\- Established contraindication to naltrexone (opioid dependence, in the process of opioid withdrawal or current use of opioid analgesics) or hypersensitivity to naltrexone;\n* Exposure to any other drug or experimental device in the 30 days prior to inclusion, except for occasional use of benzodiazepines;\n* Pregnancy, breastfeeding or patients who intend to become pregnant during the study;\n* Evidence of renal failure, defined as serum creatinine levels\\> 133 mmol \u002F L in men and\\> 124 mmol \u002F L in women, which correspond to\\> 1.51 mg \u002F dl and\\> 1.41 mg \u002F dl, respectively on Week 1 of inclusion;\n* Evidence of clinically significant liver failure (defined as AST or ALT\\> 2 times the upper limit of normal) in Week 1 of inclusion;\n* Significant cardiovascular disease, including a history of myocardial infarction in the last 5 years, stroke, clinically significant heart valve disease, unstable angina, clinically abnormal ECG, arrhythmia or congestive heart failure, determining functional class III or IV (NYHA, 1964);\n* Uncontrolled hypertension (defined as a diastolic blood pressure of 100 mm \u002F Hg and \u002F or a systolic blood pressure of 180 mm \u002F Hg with or without medication). Hypertensive patients receiving medication should be receiving the same dose of the same antihypertensive medication for at least two months;\n* Evidence of uncontrolled thyroid disorders, including hyper or hypothyroidism or abnormal TSH level. Patients who are known to have thyroid hormone replacement need to have had a stable dose for at least three months prior to inclusion and a normal TSH level upon inclusion\n* History or current comorbidity with bipolar affective disorder, obsessive compulsive disorder, psychotic disorder, schizophrenia or severe depression, additionally verified through the Patient Health Questionnaire 9 (PQH-9\\> 19), current suicide risk, or any other neuropsychiatric condition in severe cognitive impairment;\n* Current or previous history (in the previous two years) of abuse \u002F dependence on alcohol or other psychoactive substance (except nicotine);\n* If at any moment the clinician responsible for the patient identifies suicidal ideation with risk of self-harm, or death;\n* Clinically significant hematological or immunological disorder;\n* Patients currently receiving psychotropic medications, except for the episodic use of benzodiazepines;\n* Illiteracy, or any other condition that prevents the reading and understanding of the research instruments;\n* Do not have a telephone line available for remote monitoring;\n* Living alone, or not being able to present a family member capable of providing collateral information on gaming behavior;\n* To be followed up in another therapeutic program.\n\nThe Mini International Neuropsychiatric Interview (MINI) will be used to verify the psychiatric exclusion diagnoses. This is a structured diagnostic interview, with quick application - approximately 45 minutes - compatible with the DSM-IV criteria. Its objective is the verification and standardization of the main Psychiatric Disorders of Axis 1 of DSM IV. It is performed by clinicians after rapid training (1 to 3 hours). The translated and adapted Brazilian version showed globally satisfactory reliability.","ALL","18 Years","60 Years",{"count":20,"type":21},40,"ESTIMATED","INTERVENTIONAL",[24],"PHASE2","It is a double blind controlled study to test the hypothesis that it's possible to predict the response to naltrexone in Videogame Disorder with the use of Eye Tracking device, during a period of 12 weeks",[27],"Gaming Disorder",[29,30,31,32,33],"Videogame disorder","Gaming disorder","eye tracking","naltrexone","problematic videogame users","RECRUITING","2026-07-23",{"date":37,"type":38},"2026-07-27","ACTUAL",{"date":40,"type":38},"2026-07-01",{"date":42,"type":21},"2027-07",{"name":44,"class":45},"University of Sao Paulo","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":16,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":22,"phases":59,"briefSummary":61,"conditions":62,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":46},"100611844","evaluation-of-a-family-centered-program-for-problematic-gamingexcessive-screen-use-100611844","NCT07245862","Evaluation of a Family-centered Program for Problematic Gaming\u002FExcessive Screen Use","Evaluation of a Family-centered Program for Problematic Gaming\u002FExcessive Screen Use in a Child and Adolescent Population Within Social Services in Light of the New Social Services Law","S-FAME","Inclusion Criteria:\n\n* family conflicts related to screen use\n* spaeks and udnerstand swedish\n\nExclusion Criteria:\n\n* se above","11 Years","14 Years",{"count":58,"type":21},170,[60],"NA","The Family-Centered Program for Problematic Gaming and Excessive Screen Use (FAME) is a pioneering initiative designed to address the growing challenges of excessive screen use and gaming among children and adolescents, particularly within family dynamics.",[63,64,27,65],"Adolescent Behavior","Social Media Addiction","Family Relations","2026-04-24",{"date":68,"type":38},"2026-04-30",{"date":70,"type":38},"2026-01-01",{"date":72,"type":21},"2028-01-01",{"name":74,"class":45},"Region Skane",{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":81,"sex":16,"minAge":82,"maxAge":17,"enrollmentInfo":83,"targetDuration":4,"studyType":22,"phases":85,"briefSummary":86,"conditions":87,"keywords":88,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":46},"100620917","a-study-to-evaluate-the-effectiveness-of-group-gaming-interventions-for-individuals-with-problematic-gaming-behavior-and-gaming-disorder-100620917","NCT07363850","A Study to Evaluate the Effectiveness of Group Gaming Interventions for Individuals With Problematic Gaming Behavior and Gaming Disorder.","Inclusion Criteria:\n\n* (1) Clinical diagnosis of hazardous gaming defined in the ICD-11 (2) Fully comprehending the research's purpose and procedures and signing the informed consent\n\nExclusion Criteria:\n\n* (1)Serious physical illness or intellectual disability (2) Clinical diagnosis of gaming disorder (3) Not completing all the interventions or assessments",true,"12 Years",{"count":84,"type":21},100,[60],"This is a randomized, parallel-group, two-arm study design registered with the Chinese Clinical Trial Registry. The study divides participants into an intervention group and a control group in the same ratio. The participants in the intervention group will receive a series of game-based activities and treatment. Firstly, we will distribute the recruitment advertisements for this intervention program in the school, including the project introduction, registration code, and contact details. Secondly, if students are interested in this project, they need to screen the code, and completely fill in personal information, and the screening questionnaire. Thirdly, students reaching the inclusion criteria and their parents will be invited to participate in a project briefing session and obtain their informed consent. Lastly, three times assessments in the whole process will be conducted, preintervention(T0), post-intervention(T1), and at a three-month(T3) follow-up. Importantly, participants can quit the project at any time during the whole process.",[27],[27],"2026-01-14",{"date":91,"type":38},"2026-01-23",{"date":93,"type":38},"2025-10-01",{"date":95,"type":21},"2026-12-31",{"name":97,"class":45},"Shanghai Mental Health Center",{"id":99,"slug":100,"hasResults":11,"nctId":101,"briefTitle":102,"officialTitle":103,"acronym":4,"eligibilityCriteria":104,"healthyVolunteers":11,"sex":16,"minAge":105,"maxAge":4,"enrollmentInfo":106,"targetDuration":4,"studyType":22,"phases":108,"briefSummary":109,"conditions":110,"keywords":112,"overallStatus":118,"whyStopped":4,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":46},"100464507","cbt-treatment-for-internet-gaming-disorder-100464507","NCT05328596","CBT Treatment for Internet Gaming Disorder","Gaming Disorder- a Randomized Controlled Trial in a Clinical Setting","Inclusion Criteria:\n\n* Fulfilling 5 out of 9 criteria for IGD according to DSM V\n* ≥ 16 years of age\n* Can read and speak Swedish fluidly.\n\nExclusion Criteria:\n\n* Somatic or psychiatric disease that is contraindicating or severely complicates the implementation of the intervention (e.g., ongoing psychotic, manic or hypomanic episode or neuropsychiatric condition with severe disability)\n* Ongoing increased suicide risk that is considered to make it inappropriate for the patient to participate in the study (based on evaluation at the structured clinical interview)\n* have another ongoing psychological treatment with a content similar to that in the current study\n* plan to start such treatment during the XX weeks that the study is ongoing or has during the last three weeks started or changed medication for any psychiatric problem.","16 Years",{"count":107,"type":21},160,[60],"For most people, gaming is perceived as a positive activity. In some cases, however, gaming may turn into an addiction with consequences for the individual health, quality of life and everyday life. Today, there is a lack of evidence-based interventions to treat this condition, called Gaming Disorder (GD). This study will evaluate a new manual for treatment of GD, divided into a number of modules and based on cognitive behavioural therapy (CBT). The study is designed as a randomized controlled trial (RCT) and will be conducted at a clinic specialized in the treatment of gambling and gaming addiction.\n\nParticipants included in the study will be randomized to one of to groups. The intervention group will receive twelve weeks of individual CBT-treatment while participants allocated to the control group will be put on a twelve-week wait-list.\n\nThe hypothesis is that the manual based CBT treatment will result in a greater reduction in symptoms of criteria for GD.",[111,27],"Internet Gaming Disorder",[113,114,115,116,117],"Psychiatry","Psychology","Cognitive Behavioural Therapy","Randomized Controlled Trial","Addictive behaviour","NOT_YET_RECRUITING","2025-05-13",{"date":121,"type":38},"2025-05-16",{"date":123,"type":21},"2025-08",{"date":125,"type":21},"2027-12",{"name":127,"class":45},"Sahlgrenska University Hospital",{"id":129,"slug":130,"hasResults":11,"nctId":131,"briefTitle":132,"officialTitle":133,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":81,"sex":16,"minAge":82,"maxAge":17,"enrollmentInfo":134,"targetDuration":4,"studyType":22,"phases":135,"briefSummary":136,"conditions":137,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":138,"lastUpdatePostDateStruct":139,"startDateStruct":141,"completionDateStruct":143,"leadSponsor":145,"locationsCount":46},"100578459","a-study-of-the-effectiveness-of-an-early-intervention-on-adolescent-hazardous-gaming-100578459","NCT06811571","A Study of the Effectiveness of an Early Intervention on Adolescent Hazardous Gaming","A Study of the Effectiveness of a Mobile-based Early Intervention on Adolescent Hazardous Gaming",{"count":84,"type":21},[60],"The investigators established a mobile-based early intervention on adolescent hazardous gaming and verified its effectiveness.",[27],"2025-02-04",{"date":140,"type":38},"2025-02-06",{"date":142,"type":38},"2022-07-01",{"date":144,"type":21},"2025-12-31",{"name":97,"class":45},{"id":147,"slug":148,"hasResults":11,"nctId":149,"briefTitle":150,"officialTitle":151,"acronym":4,"eligibilityCriteria":152,"healthyVolunteers":81,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":153,"targetDuration":4,"studyType":22,"phases":155,"briefSummary":156,"conditions":157,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":158,"lastUpdatePostDateStruct":159,"startDateStruct":161,"completionDateStruct":163,"leadSponsor":164,"locationsCount":46},"100532096","a-study-for-the-disrupted-interpersonal-interaction-among-gaming-disorder-individuals-and-treatment-100532096","NCT06208358","A Study for the Disrupted Interpersonal Interaction Among Gaming Disorder Individuals and Treatment","Brain Mechanism of Disrupted Interpersonal Interaction in Gaming Disorder Affecting Cognitive Control and Its Hierarchical Multidimensional Evaluation Intervention","Inclusion Criteria:\n\n* (1)Clinical diagnosis of severe Gaming Disorder defined in the ICD-11; (2)Normal hearing and vision, or within normal range after correction;\n\nExclusion Criteria:\n\n* (1) Clinical diagnosis of mental health disorders other than GD defined in the ICD-11 in the past 5 years；(2) Suffering from diseases that affect cognitive function (such as cerebrovascular diseases) ; (3) Schizophrenia, bipolar disorder, depression or other Axis I disorder of DSM-V criteria;(4)any contraindication for tACS intervention.",{"count":154,"type":21},60,[60],"Aiming at the major problems of unclear brain mechanism of gaming disorder and lack of effective assessment intervention tools, this project started by exploring the brain mechanism of abnormal interpersonal interaction and cognitive control deficit promoting and accelerating the development of gaming disorder, adopted a prospective cohort study design, combined with multi-modal brain functional imaging, cognitive function, social psychological assessment, and other means. To clarify the brain mechanism and outcome of gaming disorder. Based on the preliminary stage, for high-risk groups, risky gaming behavior, gaming disorder layout hierarchical multidimensional assessment intervention system, using science education, brief intervention, social psychological intervention, neural regulation, cognitive rehabilitation training, mobile medical treatment, and other ways, stratification and stage, early identification, prevention and treatment combination, accurate intervention to comprehensively reduce the occurrence and development of gaming disorder.",[27],"2024-01-05",{"date":160,"type":38},"2024-01-17",{"date":162,"type":38},"2023-09-01",{"date":95,"type":21},{"name":97,"class":45}]