[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"general-anesthesia-using-endotracheal-intubation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:general-anesthesia-using-endotracheal-intubation":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,55],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":31,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":54},"100651917","alveolar-recruitment-maneuver-induced-hypotension-a-dynamic-consequence-and-intraoperative-indicator-of-fluid-responsiveness-100651917",false,"NCT07766967","Alveolar Recruitment Maneuver-Induced Hypotension: A Dynamic Consequence and Intraoperative Indicator of Fluid Responsiveness","Alveolar Recruitment Maneuver-Induced Hypotension: A Dynamic Outcome and Intraoperative Indicator of Fluid Responsiveness","Inclusion Criteria:Age 18 years or older ASA physical status I or II Scheduled for elective non-cardiac, non-thoracic surgery under general anesthesia Able to provide written informed consent -\n\nExclusion Criteria:Cardiac or thoracic surgery Hemodynamic instability at baseline (MAP \\\u003C65 mmHg or requirement for vasopressors) Severe valvular heart disease or known cardiac dysfunction (EF \\\u003C40%) Chronic obstructive pulmonary disease (COPD) or severe respiratory disease Atrial fibrillation or other significant arrhythmias Peripheral vascular disease affecting PVI signal quality Body mass index (BMI) \\>40 kg\u002Fm² Emergency surgery Refusal to participate or inability to provide informed consent Pregnancy\n\n\\-","ALL","18 Years",{"count":19,"type":20},70,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study investigates whether two simple bedside tests - the Passive Leg Raising (PLR) test and the Pleth Variability Index (PVI) - can predict a drop in blood pressure that sometimes occurs during a lung-opening procedure called an Alveolar Recruitment Maneuver (ARM).\n\nARM is routinely performed during general anesthesia to prevent lung collapse and improve oxygen levels. However, in some patients - particularly those with low fluid levels - ARM can cause a temporary but significant drop in blood pressure (hypotension), which may require immediate treatment.\n\nIn this prospective observational study, adult patients scheduled for elective non-cardiac, non-thoracic surgery under general anesthesia will be enrolled. Before each ARM is performed, PLR test and PVI values will be measured. We will then evaluate how well these measurements predict whether the patient will develop ARM-induced hypotension.\n\nIf PLR and PVI can reliably identify patients at risk, clinicians may be able to take preventive steps before performing ARM, making the procedure safer for vulnerable patients.",[26,27,28,29,30],"Hypotension Drug-Induced","General Anesthesia Using Endotracheal Intubation","Atelectasis","Fluid Responsiveness","Mechanical Ventilation",[32,33,34,35,36,37,38,39,40,41],"Alveolar Recruitment Maneuver","Passive Leg Raising","Pleth Variability Index","hypotension","Fluid responsiveness","Dynamic preload indicators","Intraoperative monitoring","General anesthesia","Lung-protective ventilation","Perioperative hemodynamics","NOT_YET_RECRUITING","2026-08-11",{"date":45,"type":46},"2026-08-17","ACTUAL",{"date":48,"type":20},"2026-07-15",{"date":50,"type":20},"2026-09-29",{"name":52,"class":53},"University of Health Sciences Balikesir Hospital Eduation and Research","OTHER_GOV",1,{"id":56,"slug":57,"hasResults":11,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":4,"eligibilityCriteria":61,"healthyVolunteers":11,"sex":16,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":4,"studyType":66,"phases":4,"briefSummary":67,"conditions":68,"keywords":69,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":54},"100597673","algorithm-predicting-intraoperative-changes-in-cardiac-output-using-capnography-100597673","NCT07061548","Algorithm Predicting Intraoperative Changes in Cardiac Output Using Capnography","Development of an Artificial Intelligence Model for Predicting Intraoperative Changes in Cardiac Output Using Capnography During General Anesthesia","Inclusion Criteria:\n\n* Elective surgery under general anesthesia\n* Adult patients (18 \\\u003C age \\\u003C 76)\n* Patients who were monitored invasive arterial blood pressure (waveform) and capnography (numeric)\n\nExclusion Criteria:\n\n* Emergency surgery\n* Cardiovascular and thoracic surgery\n* Known Asthma and Chronic obstructive pulmonary disease (COPD)\n* Preoperative pulmonary function test (PFT) abnormality over moderate grade\n* Intraoperative monitoring duration less than 30 minutes","19 Years","75 Years",{"count":65,"type":20},2005,"OBSERVATIONAL","Conventional monitoring of cardiac output requires an invasive procedure and an additional device, which can lead to increased risk and cost. Investigators developed an artificial intelligence algorithm to predict intraoperative changes in cardiac output using capnography in patients undergoing surgery under general anesthesia.",[27],[70,71,72,73],"artificial intelligence","general anesthesia","capnography","cardiac output","RECRUITING","2025-07-15",{"date":77,"type":46},"2025-07-18",{"date":79,"type":46},"2025-07-03",{"date":81,"type":20},"2025-12-31",{"name":83,"class":84},"Samsung Medical Center","OTHER"]