[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"geriatric-hip-fracture\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:geriatric-hip-fracture":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100652832","efficacy-of-oral-nutritional-supplement-in-femoral-neck-fracture-patients-undergoing-hip-arthroplasty-100652832",false,"NCT07780006","Efficacy of Oral Nutritional Supplement in Femoral Neck Fracture Patients Undergoing Hip Arthroplasty","Efficacy of Oral Nutritional Supplement in Femoral Neck Fracture Patients Undergoing Hip Arthroplasty: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Femoral neck fracture patients undergoing hip arthroplasty (Total hip arthroplasty or bipolar hemiarthroplasty)\n* Age ≥ 65 years\n* American Society of Anesthesiologists (ASA) class I-III\n* Participants understand and consent to the protocol of the trial\n\nExclusion Criteria:\n\n* Pathologic fracture or high impact fracture\n* Morbid obesity (Body mass index \\> 40)\n* Chronic kidney disease (Chronic kidney disease stage \\> 3b or estimated glomerular filtration rate (eGFR) \\\u003C 30)\n* Thyroid disease or endrocrinopathy\n* Gastrointestinal intolerance preventing oral supplementation or Malabsorption syndromes\n* Malignancy with radiotherapy or chemotherapy\n* Cognitive disorder\n* Decompensated Liver Disease or Cirrhosis Child-Pugh Class B-C\n* Known allergy\u002Fintolerance to milk or other supplement ingredients","ALL","65 Years",{"count":19,"type":20},60,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study aim to compare the efficacy of oral nutritional supplementation (ONS) in femoral neck fracture patients undergoing hip arthroplasty compared with placebo. The hypothesis is \"Oral nutritional supplement with Beta-hydroxy-beta-methylbutyrate (HMB) can improve muscle strength in femoral neck fracture patients undergoing hip arthroplasty\".\n\nFemoral neck fracture patients aged more than 65 years will be enrolled and allocated into 2 groups\n\n* ONS group: Oral nutritional supplement (Ensure® Plus Advance) 2 serves \u002F day x 30 days + Standard oral intake\n* Control group: Standard oral intake\n\nPrimary outcome is Grip strength, assessed using hand dynamometer on admission and 2, 6, 12 weeks postoperatively.\n\nSecondary outcomes are\n\n* Serum albumin assessed on admission and 2, 6, 12 weeks postoperatively\n* Barthel index assessed at 2, 6, 12 weeks postoperatively\n* Mini Nutritional Assessment (MNA), Geriatric Nutritional Risk Index (GNRI) assessed at 2, 6, 12 weeks postoperatively\n* Length of stay (day)\n* Time up and go (TUG), assessed at 2, 6, 12 weeks postoperatively\n* Oxford hip score (OHS), assessed at 2, 6, 12 weeks postoperatively\n* Complications, rate of readmission, mortality rate assessed until 3 months",[26,27,28],"Femoral Neck Fractures","Geriatric Hip Fracture","Hip Fracture, Post Surgery Recovery, Muscle Resilience",[30,31,32],"Femoral neck fractures","Oral nutritional supplementation","HMB","NOT_YET_RECRUITING","2026-08-18",{"date":36,"type":37},"2026-08-21","ACTUAL",{"date":39,"type":20},"2026-10",{"date":41,"type":20},"2027-12",{"name":43,"class":44},"Thammasat University","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":21,"phases":55,"briefSummary":56,"conditions":57,"keywords":4,"overallStatus":58,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":45},"100575493","nutritional-supplementation-in-geriatric-hip-fractures-100575493","NCT06773000","Nutritional Supplementation in Geriatric Hip Fractures","Can Complex Carbohydrates and Essential Amino Acid Supplementation Improve Outcomes Following Geriatric Hip Fractures","Inclusion Criteria:\n\n1. Male or female, aged 65 years or older.\n2. Presenting with a geriatric hip fracture (femoral neck, intertrochanteric, or subtrochanteric) requiring surgical intervention.\n3. Able to provide informed consent.\n4. Expected to survive at least 6 months after surgery, with no terminal illness.\n\nExclusion Criteria:\n\n1. Pre-existing conditions that significantly impair mobility prior to injury.\n2. Severe renal or liver impairment.\n3. Active treatment with investigational drugs or participation in another clinical trial within the last 30 days.\n4. Inability to tolerate oral nutritional supplementation due to gastrointestinal disorders.\n5. Allergies to any components of the nutritional supplement being tested.",{"count":54,"type":20},118,[23],"This study is a randomized controlled trial comparing outcomes between geriatric hip fractures who received a commercially available (XR RecoveryTM, Salt Lake City Utah) peri-operative nutritional supplement for three weeks post-operatively to those who receive standard nutritional counseling. The main question it aims to answer is:\n\n\\- Does supplementation decrease muscle loss via ultrasound measurements of the cross-sectional area of the rectus femoris of the uninjured leg?",[27],"RECRUITING","2026-03-02",{"date":61,"type":37},"2026-03-03",{"date":63,"type":37},"2025-01-16",{"date":65,"type":20},"2027-06-30",{"name":67,"class":44},"NYU Langone Health"]