[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"git-function\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:git-function":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":5},"100618308","dexamethasone-dexmedetomidine-and-their-combination-on-post-op-git-function-measured-by-i-ffed-score-post-laparoscopic-cholecystectomy-100618308",false,"NCT07329933","Dexamethasone, Dexmedetomidine and Their Combination on Post op. GIT Function Measured by I-FFED Score Post Laparoscopic Cholecystectomy","Effect of Dexamethasone, Dexmedetomidine and Their Combination on Postoperative Gastrointestinal Function Measured by I-FEED Score After Elective Laparoscopic Cholecystectomy Surgery: a Randomized Controlled Trial","vomiting","Inclusion Criteria:\n\n* . Age 18-65 years.\n* American Society of Anesthesiologists (ASA) physical status I or II.\n* Scheduled for elective laparoscopic cholecystectomy surgery under general anesthesia.\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Known allergy or contraindication to any study drug (dexamethasone, dexmedetomidine, or placebo).\n* Pre-existing gastrointestinal motility disorders (e.g., gastroparesis, inflammatory bowel disease).\n* Chronic use of opioids, steroids, or antiemetics.\n* History of severe cardiac disease (e.g., high-grade AV block, severe bradycardia).\n* Uncontrolled diabetes mellitus (HbA1c \\> 8.0%).\n* Emergency surgery or conversion to open surgery.\n* Pregnancy or breastfeeding.\n* Morbid obesity (BMI \\>40).\n* Severe hepatic or renal dysfunction.","ALL","18 Years","65 Years",{"count":21,"type":22},160,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this clinical trial is to learn the effect of Dexamethasone and Dexmedetomidine and Their Combination on Post op. GIT Function Measured by I-FFED Score Post Laparoscopic Cholecystectomy\n\nWhat medical problems do participants have when taking Dexamethasone and Dexmedetomidine? Researchers will compare Dexamethasone and Dexmedetomidine and Their Combination to a placebo (a look-alike substance that contains no drug) to see the effect on Post op. GIT Function Measured by I-FFED Score Post Laparoscopic Cholecystectomy Participants will receive Dexamethasone 8 mg IV + Saline IV (total volume 10 ml) over 10 minutes administered after induction of anesthesia.\n\nParticipants will receive Dexmedetomidine 0.5 mcg \u002Fkg IV + Saline IV (total volume 10 ml) over 10 minutes administered after induction of anesthesia.\n\nParticipants will receive Dexamethasone 8 mg IV + Dexmedetomidine 0.5 mcg\u002Fkg IV+ Saline IV (total volume 10 ml) over 10 minutes administered after induction of anesthesia.\n\nParticipants will receive Saline IV (total volume 10 ml) over 10 minutes administered after induction of anesthesia",[28,29,30,31,32],"GIT Function","Cholecystectomy, Laparoscopic","Dexamethasone","Dexmedetomidine","I-FEED Score","RECRUITING","2026-07-16",{"date":36,"type":37},"2026-07-20","ACTUAL",{"date":39,"type":37},"2025-12-15",{"date":41,"type":22},"2026-08-01",{"name":43,"class":44},"Benha University","OTHER"]