[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"golfers-elbow\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:golfers-elbow":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,54],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":53},"100647845","hyaluronic-acid-versus-platelet-rich-plasma-for-chronic-tendinopathy-and-enthesopathy-100647845",false,"NCT07714811","Hyaluronic Acid Versus Platelet-Rich Plasma for Chronic Tendinopathy and Enthesopathy","Comparative Analysis of the Efficacy of Hyaluronic Acid and Platelet-Rich Plasma Injections in the Treatment of Chronic Tendinopathies and Enthesopathies: A Prospective, Randomized Comparative Study","Inclusion Criteria:\n\n* Chronic tendinopathy or enthesopathy of the Achilles tendon or tendon insertion in the elbow region (medial epicondylopathy, so-called golfer's elbow)\n* Symptom duration exceeding 3 months\n* Pain intensity of at least 40 millimeters (mm) on a 100-mm Visual Analog Scale (VAS)\n* Age 18-65 years\n* Signed written informed consent\n\nExclusion Criteria:\n\n* Previous surgical treatment of the studied tendon or tendon insertion\n* Prior injection of corticosteroids, platelet-rich plasma (PRP), or hyaluronic acid into the area being studied within 3 months before enrollment\n* Active systemic or local infection at the planned injection site\n* Systemic inflammatory or autoimmune disease involving the joints, including rheumatoid arthritis, spondyloarthritis, or systemic lupus erythematosus\n* Pregnancy or breastfeeding\n* Body mass index (BMI) of 40 kilograms per square meter (kg\u002Fm²) or greater","ALL","18 Years","65 Years",{"count":20,"type":21},80,"ESTIMATED","INTERVENTIONAL",[24],"NA","Chronic tendinopathies and enthesopathies are common musculoskeletal conditions in orthopedics and sports medicine, frequently leading to pain, impaired function, and significantly reduced quality of life. Their pathogenesis involves tissue degeneration and ineffective repair response, often without an active inflammatory process.\n\nStandard conservative management based on physiotherapy and activity modification is often prolonged and not always satisfactory. Minimally invasive injectable interventions supporting tendon and enthesis regeneration represent a promising alternative due to their favorable safety profile and outpatient feasibility.\n\nHyaluronic acid (HA) is a glycosaminoglycan naturally present in connective tissues. In the context of tendinopathy, it is thought to modulate inflammatory processes, provide mechanical protection by reducing friction and adhesion within the tendon sheath, and support the proper organization of collagen fibers in the tendon matrix.\n\nPlatelet-rich plasma (PRP) is an autologous concentrate of platelets providing high local concentrations of growth factors, including platelet-derived growth factor (PDGF), transforming growth factor beta (TGF-β), and vascular endothelial growth factor (VEGF), which initiate and support repair processes, cellular proliferation, and angiogenesis.\n\nThis prospective, randomized, open-label, two-arm study aims to compare the clinical efficacy of hyaluronic acid (HA) and platelet-rich plasma (PRP) injections in 80 participants with chronic Achilles tendinopathy or medial epicondylopathy of the elbow. Participants will be randomly assigned in a 1:1 ratio to receive either two HA injections or two PRP injections administered two weeks apart under ultrasonographic guidance. Follow-up will continue for 12 months after the second injection. The primary outcomes are the changes from baseline to 6 months in pain intensity measured using a 100-millimeter (mm) Visual Analog Scale (VAS), upper-limb function measured using the Quick Disabilities of the Arm, Shoulder and Hand (QuickDASH) questionnaire in participants with medial epicondylopathy, and Achilles tendon symptoms and function measured using the Victorian Institute of Sport Assessment-Achilles (VISA-A) questionnaire in participants with Achilles tendinopathy. The results will provide evidence to support the selection of injectable treatment for chronic tendinopathies and enthesopathies.",[27,28,29,30,31],"Tendinopathy","Enthesopathy","Achilles Tendinopathy","Golfer's Elbow","Medial Epicondylitis",[33,34,35,36,37,38,39,40],"PRP","hyaluronic acid","tendinopathy","enthesopathy","Achilles tendon","epicondylopathy","platelet-rich plasma","intratendinous injection","RECRUITING","2026-07-14",{"date":44,"type":45},"2026-07-20","ACTUAL",{"date":47,"type":45},"2026-06-10",{"date":49,"type":21},"2028-06",{"name":51,"class":52},"Ortonika Orthopedic Medical Clinic in Lublin","OTHER",1,{"id":55,"slug":56,"hasResults":11,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":60,"eligibilityCriteria":61,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":62,"targetDuration":4,"studyType":22,"phases":64,"briefSummary":65,"conditions":66,"keywords":69,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":4},"100634840","effects-of-peripheral-repetitive-peripheral-magnetic-stimulation-on-individuals-with-elbow-or-wrist-chronic-pain-100634840","NCT07544914","Effects of Peripheral Repetitive Peripheral Magnetic Stimulation on Individuals With Elbow or Wrist Chronic Pain","Effects of Peripheral Repetitive Peripheral Magnetic Stimulation on Individuals With Elbow or Wrist Chronic Pain, A Pilot Randomized Controlled Trial","rPMS","Inclusion Criteria:\n\n* Clinical diagnosis or self-reported history consistent with either medial or lateral epicondylitis or carpal tunnel syndromes.\n* Presence of chronic pain in the target area (mentioned above) at the time of enrollment.\n* Ability to understand the study procedures and provide informed consent.\n\nExclusion Criteria:\n\n* Contraindications to peripheral magnetic stimulation, including implanted electronic medical devices or metallic implants in locations deemed unsafe for stimulation.\n* Open wounds, active skin conditions, or other local conditions at the stimulation site.\n* Current neurological, musculoskeletal, or systemic medical conditions that, in the opinion of the investigators, would interfere with safe participation or interpretation of study outcomes.\n* Current upper-limb injury or condition other than tennis\u002Fgolfer elbow or carpal tunnel syndromes that could confound pain or perfusion measurements.\n* Pregnancy.\n* Inability to tolerate the stimulation or measurement procedures.\n* Inability to adequately understand study instructions or provide informed consent.",{"count":63,"type":21},40,[24],"This pilot, randomized, sham-controlled, single-blind study will evaluate the effectiveness of repetitive peripheral magnetic stimulation (rPMS) in reducing pain in adults with tennis\u002Fgolfer's elbow or carpal tunnel syndrome. Approximately 40 participants will be randomly assigned to active or sham stimulation delivered over two consecutive days. Outcomes, including pressure pain threshold, subjective pain ratings, and local tissue oxygenation (fNIRS), will be assessed at baseline, immediately post-intervention, and during follow-up up to 6 months to evaluate both clinical effects and underlying physiological mechanisms.",[67,30,68],"Tennis Elbow Syndrome","Carpal Tunnel Syndrome (CTS)",[60,70,71,72,73],"elbow","wrist","chronic pain","NIRS","NOT_YET_RECRUITING","2026-04-21",{"date":77,"type":45},"2026-04-27",{"date":79,"type":21},"2026-05-01",{"date":81,"type":21},"2027-12-30",{"name":83,"class":52},"University of Manitoba"]