[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hamstring-muscle-strain\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hamstring-muscle-strain":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,56,83],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":39,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":44,"lastUpdatePostDateStruct":45,"startDateStruct":48,"completionDateStruct":50,"leadSponsor":52,"locationsCount":55},"100648278","acute-effects-of-neurodynamics-on-strength-and-endurance-in-athletes-100648278",false,"NCT07721220","Acute Effects of Neurodynamics on Strength and Endurance in Athletes","Acute Effects of Neurodynamics on Strength and Endurance in Athletes: A Randomized Control Trial","Inclusion Criteria:\n\n* Participants must be between 18 and 30 years of age.\n* Must be able to read, understand, and provide informed consent, in English.\n* Must be currently participating in an organized sport (e.g. collegiate, club, or competitive recreational level) or engaging in structured resistance training and athletic conditioning for recreational sports events (e.g 5k, marathon, Crossfit, Hyrox, etc).\n* Medically stable with no known contraindications to physical exertion.\n* Cleared for participation in strength or maximal-effort isometric testing.\n* Be able to perform lower extremity isometric testing without pain that limits maximal effort.\n* Must have 2 lower extremities capable to producing full range knee flexion and extension range of motion.\n* No medical condition that significantly alters lower extremity neuromuscular performance.\n* No history of lower extremity surgery in the past 12 months.\n\nExclusion Criteria:\n\n* Individuals younger than 18 or older than 30.\n* Acute lower extremity injury in the last 12 weeks.\n* Lower extremity surgery within the last 12 months.\n* Pain in either lower extremity that would limit maximal physical exertion.\n* History of neurological disorders, including but not limited to: Neuropathy, Stoke, MS, Parkinson's Disease, etc.\n* Use of medications that significantly impact neuromuscular performance, strength or fatigue.\n* No supplementation that affects neuromuscular performance, strength, or fatigue.\n* Unable to read and understand English.\n* Not in a vulnerable population: Pregnant, mentally or physically challenged, cognitively impaired.",true,"ALL","18 Years","30 Years",{"count":21,"type":22},45,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study explores the acute effects of neurodynamics, an intervention commonly used by physical therapist to improve nerve mobility and decrease pain, on the strength and muscular endurance in the athletic population. This study aims to find if these interventions can maintain or promote strength and endurance in the hamstrings. The studies results will help physical therapist better prescribe exercise and hands-on treatment for hamstring and sciatic nerve related conditions and injuries.",[28,29,30,31,32,33,34,35,36,37,38],"Sciatic Leg Pain","Hamstring Muscle Tightness","Hamstring Muscle Strain","Hamstring Muscle Strength","Hamstring Injuries","Hamstring Injury Prevention","Hamstring Rupture","Sciatic Nerve Injury","Sciatic Radiculopathy","Lumbar Disc Herniation With Radiculopathy","Lumbar Disc Herniation",[40,41,42],"hamstring","sciatic nerve","athlete","RECRUITING","2026-07-20",{"date":46,"type":47},"2026-07-22","ACTUAL",{"date":49,"type":47},"2026-06-15",{"date":51,"type":22},"2026-07",{"name":53,"class":54},"High Point University","OTHER",1,{"id":57,"slug":58,"hasResults":11,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":4,"eligibilityCriteria":62,"healthyVolunteers":11,"sex":63,"minAge":18,"maxAge":64,"enrollmentInfo":65,"targetDuration":4,"studyType":23,"phases":67,"briefSummary":68,"conditions":69,"keywords":70,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":55},"100636730","effectiveness-of-dry-needling-in-athletes-with-chronic-hamstring-strain-100636730","NCT07569484","Effectiveness of Dry Needling in Athletes With Chronic Hamstring Strain","Effectiveness of Dry Needling on Athletes With Chronic Hamstring Strain","Inclusion Criteria:\n\n* Male football players aged 18 to 35 years.\n* Diagnosed with chronic hamstring strain (CHS) confirmed by ultrasonography.\n* Injury duration of more than 3 months.\n* Classified as Grade I or Grade II hamstring strain.\n* Currently participating in the competitive phase of football.\n* Body Mass Index (BMI) between 21-25 kg\u002Fm².\n\nExclusion Criteria:\n\n* Previous exposure to dry needling therapy.\n* Presence of any other current lower limb injuries.\n* Participation in another hamstring rehabilitation program.\n* Active skin infection at or near the treatment area.\n* Bleeding disorders or use of anticoagulant medications.\n* Severe needle phobia or psychological intolerance to needling.\n* Presence of neuromuscular disorders (e.g., muscular dystrophy or peripheral neuropathy).","MALE","35 Years",{"count":66,"type":22},38,[25],"This study aims to evaluate the effectiveness of dry needling in reducing pain and improving functional outcomes in athletes with chronic hamstring strain. Chronic hamstring injuries are common among athletes and often lead to persistent pain, reduced performance, and limitations in daily and sports activities.\n\nDry needling is a therapeutic technique used to target myofascial trigger points and relieve muscle tension. This study will compare the effects of dry needling with conventional physiotherapy interventions to determine its role in managing chronic hamstring strain.\n\nParticipants will be athletes diagnosed with chronic hamstring strain. Outcomes will include pain intensity, muscle flexibility, and functional performance. The results of this study may help improve rehabilitation strategies and provide evidence for the use of dry needling in sports injuries.",[30],[71,72],"Dry Needling","Hamstring Strain","NOT_YET_RECRUITING","2026-04-29",{"date":76,"type":47},"2026-05-06",{"date":78,"type":22},"2026-05-01",{"date":80,"type":22},"2027-04-30",{"name":82,"class":54},"Cairo University",{"id":84,"slug":85,"hasResults":11,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":89,"eligibilityCriteria":90,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":91,"enrollmentInfo":92,"targetDuration":4,"studyType":23,"phases":94,"briefSummary":96,"conditions":97,"keywords":99,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":113,"completionDateStruct":115,"leadSponsor":117,"locationsCount":55},"100626585","phase-2-bpc-157-for-acute-hamstring-muscle-strain-repair-100626585","NCT07437547","BPC 157 for Acute Hamstring Muscle Strain Repair","A Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial of Pentadecapeptide BPC 157 for Accelerated Repair of Acute Grade II Hamstring Strain Confirmed by MRI","BPC-HAMSTR","Inclusion Criteria:\n\n* Age 18 to 45 years.\n* Acute posterior thigh pain consistent with hamstring strain with onset within 72 hours prior to screening.\n* MRI-confirmed grade II hamstring strain of the biceps femoris, semitendinosus, or semimembranosus, with measurable lesion.\n* Pre-injury physical activity \\>= 3 sessions\u002Fweek or participation in organized recreational sport.\n* Willingness to follow the standardized rehabilitation protocol and attend all study visits.\n* For participants of childbearing potential: negative pregnancy test at baseline and agreement to use effective contraception during dosing and for 30 days after last dose.\n\nExclusion Criteria:\n\n* Grade III hamstring tear, tendon avulsion, or injury requiring surgical management.\n* Concomitant lower extremity injury that would interfere with rehabilitation or outcome assessment.\n* Prior hamstring strain on the index limb within the past 6 months.\n* Use of systemic corticosteroids, anabolic agents, platelet-rich plasma, stem-cell products, or investigational peptides\u002Fgrowth factors within 30 days prior to screening.\n* Known bleeding disorder or current therapeutic anticoagulation.\n* Significant uncontrolled medical illness (e.g., severe cardiovascular, hepatic, or renal disease) that increases study risk.\n* Known allergy or hypersensitivity to components of the investigational product or placebo.\n* Pregnant or breastfeeding.\n* Current participation in another interventional clinical study or participation within 30 days prior to screening.\n* Currently subject to a formal anti-doping testing program (e.g., WADA\u002FUSADA-aligned) where use of an investigational peptide could create a regulatory conflict, unless explicitly approved by the relevant authority","45 Years",{"count":93,"type":22},120,[95],"PHASE2","This randomized, double-blind, placebo-controlled Phase 2 study evaluates whether pentadecapeptide BPC 157 (BPC-157), an investigational peptide, can speed structural healing and functional recovery after an acute grade II hamstring muscle strain. Participants will receive BPC 157 or placebo for 14 days in addition to a standardized rehabilitation program. The co-primary endpoints are time to return to unrestricted sport and change in MRI-assessed injury volume at Day 14.",[30,98],"Skeletal Muscle Injury",[100,101,102,103,104,105,106,107,108,109],"BPC 157","BPC-157","pentadecapeptide","muscle strain","hamstring injury","sports medicine","MRI","return to play","muscle repair","rehabilitation","2026-02-22",{"date":112,"type":47},"2026-02-27",{"date":114,"type":47},"2026-02-02",{"date":116,"type":22},"2028-02-17",{"name":118,"class":119},"Hudson Biotech","INDUSTRY"]