[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hard-to-heal-wounds\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hard-to-heal-wounds":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,50,86],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100650344","effect-of-a-coordinated-primary-care-based-mdt-model-on-the-treatment-of-hard-to-heal-ulcers-100650344",false,"NCT07747896","Effect of a Coordinated Primary-care-Based MDT-model on the Treatment of Hard-to-heal Ulcers","Effect of a Coordinated Primary-care-Based MDT-model on the Treatment of Hard-to-heal Ulcers; a Randomized Clinically Controlled Trial","TSS","Inclusion Criteria:\n\n* Patients aged 18 years or above\n* Hard-to-heal ulcer(s)\n* Able to understand written and oral information\n* Ability to follow planned visits and treatment\n* Able to provide informed consent in Danish and\u002For English\n\nExclusion Criteria:\n\nRevascularization procedure in the affected limb planned, or undertaken within the 4 weeks prior to screening\n\n* Toe blood pressure \\\u003C 35mmHg\n* Infections of the ulcer needing acute or sub-acute (defined as within seven days) surgical treatment\n* Prior major amputations on affected or contralateral leg\n* Current treatment with cytotoxic drugs or with systemically administered glucocorticoids\n* Likely inability to comply with the need for planned visits because of planned activities\n* Participation in another interventional ulcer-healing trial within the 4 weeks prior to screening\n* Prior enrolment in this trial\n* Judgement by the investigator that the patient does not have the capacity to understand the study procedures or provide written informed consent","ALL","18 Years",{"count":20,"type":21},80,"ESTIMATED","INTERVENTIONAL",[24],"NA","The TSS project is a study of the effects of treating hard-to-heal ulcers in a multidisciplinary cross sectional team, meaning that nurse and doctor from a hospital based wound healing clinic and wound care nurse from the primary care sector treat the patient in collaboration rather than the current form where care in municipalities and hospital setting, communicate but treat the patient on their own. The study is designed as a randomized study, meaning that individuals with hard-to-heal ulcers are randomly designated to standard care or the multidis-ciplinary team. We measure several aspects of the new format, but the main outcome com-pared between the two groups (standard care and multidisciplinary care) is number of ulcers healed.\n\nParticipants are followed for a year after inclusion in the study, and have 6 fixed visits in the clinic, with the possibility of more visits if necessary.\n\nThere is no \"new\" medicine, surgery or other treatments planned in the study, but the multi-disciplinary team can offer and implement any treatment deemed appropriate for the individ-ual that is allocated to the multidisciplinary team, of course the individual has the opportunity to decline any treatment offered by the team. The control group, i.e. individuals allocated to standard care, will receive the treatment that is normally available to individuals with hard-to-heal ulcers treated in the municipality, including referral to hospital based treatments.",[27,28,29,30,31],"Diabetic Foot Disease","Diabetic Foot Infection","Diabetic Foot Ulcer (DFU)","Ulcer","Hard to Heal Wounds",[33,34,35,36],"Diabetic Foot Ulcer","MDT","Hard-to-heal ulcer","Cross Sectional Collaboration","RECRUITING","2026-08-04",{"date":40,"type":41},"2026-08-05","ACTUAL",{"date":43,"type":21},"2026-08-01",{"date":45,"type":21},"2028-10-31",{"name":47,"class":48},"Nordsjaellands Hospital","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":59,"conditions":60,"keywords":65,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":49},"100638268","ai-based-wound-monitoring-automated-wound-progression-assessment-via-marker-free-image-sequence-100638268","NCT07619430","AI-Based Wound Monitoring: Automated Wound Progression Assessment Via Marker-Free Image Sequence","Inclusion Criteria:\n\n* (1) Presence of a hard-to-heal wound that has remained unhealed for more than one month. (2)The wound can be photographed according to the standardized imaging protocol. (3)The participant was aged 18 years or older and provided informed consent personally or via a legally authorized representative, with a signed informed consent form.\n\nExclusion Criteria:\n\n* Wounds whose margins could not be fully included within the imaging field.",{"count":57,"type":21},1000,"OBSERVATIONAL","This study aims to develop a low-cost, marker-free intelligent wound assessment system that can analyze wound photos taken with a standard smartphone. By comparing wound images over time, the system will generate a quantifiable Wound Progression Index (WPI) to provide objective feedback on whether a wound is improving, stable, or worsening. The long-term goal is to support early detection of wound deterioration and improve wound care in both clinical and home settings.",[61,62,63,64],"Hard-to-heal Wounds","AI (Artificial Intelligence)","Wound Care","Pressure Injuries",[66,67,68,69,70,71,72,73,74,75],"chronic wounds","wound assessment","medical AI","semantic segmentation","longitudinal image registration","marker-free","wound progression index","home-based care","telemedicine","clinical validation","NOT_YET_RECRUITING","2026-05-27",{"date":79,"type":41},"2026-06-02",{"date":81,"type":21},"2026-06-08",{"date":83,"type":21},"2027-12-31",{"name":85,"class":48},"National Taiwan University Hospital",{"id":87,"slug":88,"hasResults":11,"nctId":89,"briefTitle":90,"officialTitle":91,"acronym":4,"eligibilityCriteria":92,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":93,"enrollmentInfo":94,"targetDuration":4,"studyType":22,"phases":96,"briefSummary":97,"conditions":98,"keywords":4,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":49},"100611028","a-rct-of-moist-ag-dressing-in-chronic-wound-100611028","NCT07235254","A RCT of Moist Ag Dressing in Chronic Wound","Dry Versus Moist Ag Dressings for Local Wound Infections: A Randomized Controlled Trial on Effectiveness and Cost-Effectiveness","Inclusion Criteria:\n\n1. The patient's age ranges from 18 to 80 years old.\n2. According to the IWII wound infection staging, infected wounds are classified as local infections\\*.\n3. The wound type is ulcer, with an ulcer area ranging from 1 to 40 cm².\n4. The wound stage is in the necrosis stabilization phase, granulation growth phase, or epithelial crawling phase\\*\\*.\n5. Voluntary participation in this study and signing the informed consent form\n\nExclusion Criteria:\n\n1. Severe diseases such as acute myocardial infarction, heart failure, hepatitis, shock, and respiratory failure have not been corrected yet;\n2. The blood sugar level of diabetes is out of control, with fasting blood sugar \\> 15 mmol\u002FL and glycosylated hemoglobin ≥ 10%;\n3. There is active bleeding in the wound, and the conventional basic treatment plan cannot be implemented;\n4. Serum albumin \\\u003C 20 g\u002FL; hemoglobin \\\u003C 60 g\u002FL; platelets \\\u003C 50 × 109\u002FL;\n5. Disseminated infection or systemic infection state, and antibiotics are being used or will be used for treatment;\n6. Patients with advanced malignant tumors;\n7. The patient is in the active stage of autoimmune diseases;\n8. The patient has previously been allergic to self-adhesive soft polysilicone silver ion foam dressings (Meipikang Silver) or Anxidean Nano Silver Trauma Patch;\n9. The patient cannot cooperate or has a mental disorder;\n10. According to the investigator's judgment, the subject has clear reasons that affect wound healing and is not suitable for this study or cannot comply with the requirements of this study.","80 Years",{"count":95,"type":21},40,[24],"This study aims to explore the differences in efficacy and cost-effectiveness between self-adhesive soft polysilicone silver ion foam dressings and traditional silver dressings in local infected wounds through a prospective randomized controlled study. The goal is to provide evidence-based medical support for clinical application, further shorten the wound healing time, and reduce the economic burden on the medical system and patients.",[99,31,100,101,102],"Chronic Wound","Dressing","Wound he'a'Ling","Wound Healing","2025-11-14",{"date":105,"type":41},"2025-11-19",{"date":107,"type":21},"2025-12-01",{"date":109,"type":21},"2027-09-01",{"name":111,"class":48},"Peking University Third Hospital"]