[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"health-behavior\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:health-behavior":29},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,62,0,25,[9,54,89,120,175,203,235,260,281,339,366,396,435,481,505,529,579,600,632,659,678,707,730,758,789],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":4},"100651880","whatsapp-messages-to-improve-mothers-oral-health-knowledge-and-childrens-toothbrushing-100651880",false,"NCT07765654","WhatsApp Messages to Improve Mothers' Oral Health Knowledge and Children's Toothbrushing","Effectiveness of WhatsApp-Based Messages as an Adjunct to Oral Health Education on Maternal Oral Health Knowledge and Child Toothbrushing Behavior: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Mother of at least one child aged 3 to 6 years\n* Aged 18 years or older\n* Able to read and understand Arabic\n* Owns a smartphone with an active WhatsApp account\n* Attending the Pediatric Dentistry Clinics at King Abdulaziz University Hospital at the time of recruitment\n* Willing to participate and provide informed consent\n\nExclusion Criteria:\n\n* Dental professional or dental student\n* Currently participating in another oral health education program targeting child oral health or toothbrushing practices","FEMALE","18 Years",{"count":20,"type":21},106,"ESTIMATED","INTERVENTIONAL",[24],"NA","Tooth decay is one of the most common health problems in young children in Saudi Arabia. Brushing twice a day with fluoride toothpaste is one of the most effective ways to prevent it, but preschool children cannot do this properly on their own and depend on their mothers to brush for them and to supervise them. Mothers usually receive oral health advice only once, during a dental visit, and a single session may not be enough to change daily habits at home.\n\nThis study will test whether short oral health messages sent to mothers on WhatsApp, in addition to the usual face-to-face advice, help mothers know more about toothbrushing and help their children brush better.\n\nMothers of children aged 3 to 6 years attending the Pediatric Dentistry Clinics at King Abdulaziz University Hospital in Jeddah will be invited to take part. All mothers will first answer a short questionnaire about what they know about toothbrushing and how their child currently brushes. All mothers will then receive the same 10 to 15 minute face-to-face oral health education session. After the session, each mother will be placed into one of two groups by chance, like flipping a coin. Mothers in the first group will also receive two WhatsApp messages a week for eight weeks, sixteen messages in total, covering how often to brush, how much fluoride toothpaste to use, correct brushing technique, and how to help and supervise their child. Mothers in the second group will not receive these messages.\n\nAfter eight weeks, all mothers will answer the same questionnaire again, and the answers of the two groups will be compared. Taking part involves no dental treatment or procedures beyond the child's normal care, and mothers may withdraw at any time.",[27,28,29,30,31],"Oral Health","Dental Caries","Health Behavior","Oral Hygiene","Early Childhood Caries (ECC)",[33,34,35,36,37,38,39,40,41],"WhatsApp","mHealth","Mobile Health","Toothbrushing","Preschool Children","Maternal Knowledge","Oral Health Education","Health Promotion","Saudi Arabia","NOT_YET_RECRUITING","2026-08-17",{"date":45,"type":46},"2026-08-18","ACTUAL",{"date":48,"type":21},"2026-08-30",{"date":50,"type":21},"2027-08-30",{"name":52,"class":53},"King Abdulaziz University","OTHER",{"id":55,"slug":56,"hasResults":12,"nctId":57,"briefTitle":58,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":61,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":4,"studyType":22,"phases":67,"briefSummary":68,"conditions":69,"keywords":73,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":88},"100550507","the-barts-charity-childrens-environmental-health-clinic-100550507","NCT06447974","The Barts Charity Children's Environmental Health Clinic","BCCEHC","Inclusion Criteria:\n\n* Parent\u002FGuardian able to provide written informed consent\n\nReferral made by paediatric asthma team\n\nChild aged 4-17 years at the time of consent to study\n\nA diagnosis of a chronic respiratory condition (diagnosis by a medical professional)\n\nContactable for regular follow up by the research team\n\nReasonable level of English language\n\nAbility to engage with technology and devices used in the study\n\nExclusion Criteria:\n\n* Inability to use the tools and devices in the research study\n\nInability to visit the hospital for the initial hospital visit\n\nInability to allow home environmental assessment",true,"ALL","4 Years","17 Years",{"count":66,"type":21},200,[24],"The study will be based from a newly formed NHS service, the children's environmental health service. Participants will be children with a known chronic respiratory condition. Participants will undergo personal environmental exposure monitoring as well as home environmental assessments, before personalised exposure reports will be provided including a summary of their exposure and advising mitigation strategies based on exposure patterns and behaviours. The monitoring will be repeated after introduction of mitigation strategies. This will allow a comparison of the effectiveness of each method of mitigation.",[70,29,71,72],"Environmental Exposure","Asthma in Children","Environmental Illness",[74,75,76,77],"asthma","Air pollution","environmental","Environmental health clinic","RECRUITING","2026-08-11",{"date":81,"type":46},"2026-08-13",{"date":83,"type":46},"2025-07-24",{"date":85,"type":21},"2027-06",{"name":87,"class":53},"Queen Mary University of London",2,{"id":90,"slug":91,"hasResults":12,"nctId":92,"briefTitle":93,"officialTitle":94,"acronym":95,"eligibilityCriteria":96,"healthyVolunteers":61,"sex":17,"minAge":97,"maxAge":98,"enrollmentInfo":99,"targetDuration":4,"studyType":22,"phases":101,"briefSummary":102,"conditions":103,"keywords":105,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":119},"100628834","the-ehealth-integrated-maternal-physical-activity-programme-in-prenatal-care-trial-e-impact-100628834","NCT07466797","The eHealth Integrated Maternal Physical Activity Programme in Prenatal Care Trial (E-IMPACT)","e-IMPACT: Evaluating an eHealth and Healthcare Professional Support Program to Promote Physical Activity During Pregnancy","e-IMPACT","Inclusion Criteria:\n\n1. Pregnant women (First trimester at least 4 weeks gestation)\n2. Age 21 years and above\n3. BMI 23 kg\u002Fm2 and above\n4. Physically fit to participate in moderate intensity exercise\n5. Singleton pregnancy\n\nExclusion Criteria:\n\n1. Women who have severe chronic disease such as chronic kidney disease, hypertension, asthma OR\n2. Obstetric or medical complications which might preclude women in normal levels of physical activity or exercise during pregnancy.\n3. Women who participated in other weight management programmes, or physical activity intervention studies recently (past 6 months) or concurrently\n4. Difficulty in understanding the English language","21 Years","45 Years",{"count":100,"type":21},100,[24],"This will be a proof-of-concept randomised control trial (RCT) study, where 100 pregnant women will be recruited in the first trimester of pregnancy and followed-up until delivery. It aims to test these following hypotheses:\n\n1. pregnancy is a window of opportunity to implement good lifestyle habits of physical activity and exercise as pregnant women are in regular contact with health professionals and are likely motivated and be more confident to carry out these activities according to the guidelines\n2. this integrated programme will effective in a healthcare setting, and will bring Singapore's \"Guidelines on Physical Activity and Exercise in Pregnancy\" guidelines to implementation\n3. with enhanced self-efficacy and motivation, the proportion of women engaging in adequate physical activity during pregnancy will increase to meet recommended guidelines.",[104,29],"Physical Activity",[106,107,108],"pregnancy","exercise in pregnancy","physical activity in pregnancy","2026-08-05",{"date":111,"type":46},"2026-08-10",{"date":113,"type":46},"2026-03-09",{"date":115,"type":21},"2028-12-31",{"name":117,"class":118},"KK Women's and Children's Hospital","OTHER_GOV",1,{"id":121,"slug":122,"hasResults":12,"nctId":123,"briefTitle":124,"officialTitle":125,"acronym":4,"eligibilityCriteria":126,"healthyVolunteers":12,"sex":62,"minAge":18,"maxAge":4,"enrollmentInfo":127,"targetDuration":4,"studyType":22,"phases":129,"briefSummary":130,"conditions":131,"keywords":136,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":166,"lastUpdatePostDateStruct":167,"startDateStruct":169,"completionDateStruct":171,"leadSponsor":173,"locationsCount":119},"100595447","reset-enhancing-weight-loss-in-a-digital-intervention-100595447","NCT07032571","Reset: Enhancing Weight Loss in a Digital Intervention","Enhancing Weight Loss in a Digital Intervention Among Adults With Overweight or Obesity","Inclusion Criteria:\n\n* adults (ages 18+ years)\n* body mass index (BMI) 25.0 to 45.0 kg\u002Fm\\^2\n* cellphone ownership with a texting plan\n* daily access to a personal scale\n* daily access to a personal email account\n* English language proficiency\n* interest in losing weight through behavioral strategies\n* living in the United States\n\nExclusion Criteria:\n\n* concurrent enrollment in another weight management intervention\n* loss of ≥5% body weight in the past 6 months\n* current use of a weight loss or anti-obesity medication\n* prior or planned bariatric surgery in the next 3 months\n* current pregnancy, planned pregnancy in the next 3 months, or recent pregnancy in the past 6 months\n* current breastfeeding or lactating\n* living with someone else participating in the study\n* hospitalization for a mental health condition in the past 12 months\n* inability to engage in moderate forms of physical activity akin to brisk walking\n* if weight loss is contraindicated or might be impacted by a condition (e.g., end stage renal disease, cancer, schizophrenia, dementia) or medication (e.g., steroids, antipsychotics)\n* if an individual would be better suited for a more intensive or different type of intervention based on a health condition (e.g., individuals with history of an eating disorder or cardiovascular event, uncontrolled hypertension, or uncontrolled diabetes mellitus)\n* participation in another weight loss study conducted in Dr. Patel's lab in the past 6 months\n* investigator discretion for safety reasons",{"count":128,"type":21},208,[24],"The goal of the Reset trial is to learn about the optimal combination of dietary behavior strategies in a fully digital weight loss intervention. The intervention is designed for adults with overweight or obesity. The investigators will examine the impact on weight loss of four dietary strategies: 1) limiting Red Zone Foods (i.e., foods that are high in calories and low in nutrition), 2) limiting eating windows, 3) increasing protein intake, and 4) increasing fiber intake. Each of these strategies will include goal setting, daily self-monitoring, and tailored feedback.\n\nThe investigators will recruit 208 participants. Broadly, adults with overweight or obesity who live in the U.S. will be eligible. The weight loss intervention will last 12 weeks. All participants will be asked to track their body weight daily and complete weekly behavioral lessons and action plans to promote healthy eating and physical activity. All study tasks will occur remotely. Assessment of body weight and survey measures will occur at the beginning of the trial (\"baseline\"), and at 1 month and 3 months.\n\nThe Multiphase Optimization Strategy (MOST) framework will be used to identify which combination of the dietary behavior strategies results in the greatest weight loss. In total, there will be 16 treatment conditions.",[132,133,134,29,135],"Obesity","Overweight","Weight Loss","Lifestyle Intervention",[137,138,139,140,141,142,143,144,145,146,147,148,149,150,151,152,153,154,155,156,157,158,159,160,161,162,163,164,165],"obesity","overweight","weight loss","weight","health behavior","lifestyle intervention","lifestyle modification","multiphase optimization strategy","intervention","behavior change","weight reduction","lose weight","adults","BMI reduction","body fat reduction","weight control","weight change","weight management","obesity management","obesity treatment","digital health","digital intervention","remote intervention","standalone intervention","obesity prevention","diabetes prevention","mobile health","factorial design","intervention optimization","2026-08-01",{"date":168,"type":46},"2026-08-04",{"date":170,"type":21},"2026-09",{"date":172,"type":21},"2027-03",{"name":174,"class":53},"Stanford University",{"id":176,"slug":177,"hasResults":12,"nctId":178,"briefTitle":179,"officialTitle":180,"acronym":4,"eligibilityCriteria":181,"healthyVolunteers":12,"sex":62,"minAge":182,"maxAge":97,"enrollmentInfo":183,"targetDuration":4,"studyType":22,"phases":184,"briefSummary":185,"conditions":186,"keywords":4,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":193,"lastUpdatePostDateStruct":194,"startDateStruct":196,"completionDateStruct":198,"leadSponsor":200,"locationsCount":202},"100495559","mobile-video-directly-observed-therapy-dot-for-immunosuppression-medication-adherence-in-adolescent-heart-transplant-recipients-100495559","NCT05732779","Mobile Video Directly Observed Therapy (DOT) for Immunosuppression Medication Adherence in Adolescent Heart Transplant Recipients","Mobile Video Directly Observed Therapy (DOT) for Immunosuppression Medication Adherence in Adolescent Heart Transplant Recipients: Enhancing Technological Innovation and Strengthening the Role of Small Businesses in Meeting Needs of Adolescent Organ Transplant","Inclusion Criteria:\n\n* Eligible participants are 10-21 years of age\n* Have received a heart transplant and are followed participating pediatric heart transplant centers\n* English-speaking or Spanish-speaking\n* Own a smart-phone or have access to the mobile app through other devices\n* Are willing to receive information through it\n* Have a MLVI score of greater than 2.0 over the last year\n\nExclusion Criteria:\n\n• Those with cognitive impairments will not be eligible for enrollment due to inability to provide informed assent","10 Years",{"count":100,"type":21},[24],"We will conduct a two-group randomized controlled trial to examine the eMocha DOT intervention with pediatric HT recipients.In this population, medication nonadherence remains a primary cause of late acute rejection (LAR) episodes, increased number of hospitalizations, graft failure, and patient mortality. Herein, we propose an innovative approach to promote medication adherence and improve patient and graft outcomes.",[187,188,189,190,29,191,192],"Heart Transplant Rejection","Immune Suppression","Pediatric Heart Transplant","Medication Nonadherence","Remote Monitoring","Patient Engagement","2026-07-15",{"date":195,"type":46},"2026-07-16",{"date":197,"type":46},"2024-10-01",{"date":199,"type":21},"2027-05-01",{"name":201,"class":53},"University of Florida",4,{"id":204,"slug":205,"hasResults":12,"nctId":206,"briefTitle":207,"officialTitle":208,"acronym":209,"eligibilityCriteria":210,"healthyVolunteers":61,"sex":62,"minAge":211,"maxAge":4,"enrollmentInfo":212,"targetDuration":4,"studyType":214,"phases":4,"briefSummary":215,"conditions":216,"keywords":219,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":227,"lastUpdatePostDateStruct":228,"startDateStruct":230,"completionDateStruct":232,"leadSponsor":233,"locationsCount":119},"100646661","thrive-belize-a-school-based-life-skills-program-to-support-teen-health-in-toledo-district-belize-feasibility-100646661","NCT07687199","THRIVE-Belize: A School-Based Life-Skills Program to Support Teen Health in Toledo District, Belize (Feasibility)","THRIVE-Belize: A Single-School Mixed-Methods Feasibility Trial of a Multi-Component Life-Skills Curriculum for Adolescent Health Promotion at Toledo Community College, Belize","THRIVE-Belize","Inclusion Criteria:\n\n* Students: enrolled at Toledo Community College in Forms 1-4; ages 12-18 years; able to read and comprehend English at grade level; provides written assent; has active written parental\u002Fguardian consent\n* Teachers: currently employed at TCC; teaches students in Forms 1-4; provides written informed consent\n* Parents\u002FGuardians: parent or legal guardian of an eligible TCC student; age 18 years or older; able to communicate in English, Spanish, or Q'eqchi'-Mopan Maya; provides written informed consent\n* School Principal and Administrative Staff: currently serving as principal or administrative staff at TCC; provides written informed consent\n* Community Stakeholders: recognized expertise in adolescent health, education, or youth services (e.g., healthcare providers, religious leaders, village council members, youth organization leaders); resident of Toledo District, Belize; provides written informed consent\n\nExclusion Criteria:\n\n* Cognitive or developmental limitations preventing informed assent or participation (students)\n* Declines to participate (students or parents\u002Fguardians)","12 Years",{"count":213,"type":21},280,"OBSERVATIONAL","THRIVE-Belize is a school-based program being developed to support the health and well-being of adolescents in the Toledo District of southern Belize. The program covers seven topics: communication and emotional regulation, healthy expressions of masculinity, sexual and reproductive health, healthy relationships, mental and physical health, substance use prevention, and environmental health.\n\nBefore testing whether the program works, the research team needs to learn whether students, teachers, parents, school staff, and community members find it acceptable, appropriate, and practical to deliver at Toledo Community College. This study (Phase I) does not deliver the program to anyone. Instead, it gathers feedback through surveys, focus groups, and interviews with about 280 participants across these five groups.\n\nThe information collected will be used to refine the program and decide whether to move forward to a future pilot study. No medical or educational intervention is given to participants in this phase.",[29,217,218],"Adolescence","Feasibility Studies",[220,221,222,223,224,225,226],"feasibility study","school-based intervention","life skills","adolescents","Belize","implementation science","acceptability","2026-07-03",{"date":229,"type":46},"2026-07-07",{"date":231,"type":21},"2026-07",{"date":170,"type":21},{"name":234,"class":53},"University of Arizona",{"id":236,"slug":237,"hasResults":12,"nctId":238,"briefTitle":239,"officialTitle":240,"acronym":4,"eligibilityCriteria":241,"healthyVolunteers":12,"sex":62,"minAge":242,"maxAge":4,"enrollmentInfo":243,"targetDuration":4,"studyType":22,"phases":245,"briefSummary":246,"conditions":247,"keywords":248,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":252,"lastUpdatePostDateStruct":253,"startDateStruct":255,"completionDateStruct":256,"leadSponsor":258,"locationsCount":119},"100611810","evaluation-of-cardiovascular-health-outcomes-among-survivors-2-100611810","NCT07245420","Evaluation Of Cardiovascular Health Outcomes Among Survivors 2","Evaluation Of Cardiovascular Health Outcomes Among Survivors 2 (ECHOS2)","Inclusion Criteria:\n\n* Childhood Cancer Survivor Study (CCSS) Participants\n* Age ≥26 years\n* Treated with cumulative doxorubicin equivalent anthracycline doses ≥100 mg\u002Fm2 with any\u002Fno radiation, or ≥15 Gy chest radiation with any\u002Fno anthracyclines\n* No history of cardiomyopathy\n* Has not had an echocardiogram in the previous 5 years\n* Has a history of successful completion of CCSS surveys\n* English-Speaking\n* Has not been enrolled in ECHOS-1 (pilot)\n\nExclusion Criteria:\n\n• Currently participating in a long-term follow-up program that provides risk-based screening","26 Years",{"count":244,"type":21},350,[24],"Childhood cancer survivors who received certain treatments are at a higher risk of developing heart problems in the future. This study is looking at ways to educate childhood cancer survivors about that risk and encourage them to receive a recommended heart screening test.",[29],[249,250,251],"Childhood Cancer Survivors","Cardiomyopathy Screening","eHealth Intervention","2026-06-24",{"date":254,"type":46},"2026-06-26",{"date":170,"type":21},{"date":257,"type":21},"2030-12",{"name":259,"class":53},"St. Jude Children's Research Hospital",{"id":261,"slug":262,"hasResults":12,"nctId":263,"briefTitle":264,"officialTitle":264,"acronym":4,"eligibilityCriteria":265,"healthyVolunteers":61,"sex":62,"minAge":97,"maxAge":266,"enrollmentInfo":267,"targetDuration":4,"studyType":22,"phases":269,"briefSummary":270,"conditions":271,"keywords":4,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":272,"lastUpdatePostDateStruct":273,"startDateStruct":275,"completionDateStruct":277,"leadSponsor":279,"locationsCount":119},"100610337","consumer-perceptions-of-alcoholic-beverages-100610337","NCT07226271","Consumer Perceptions of Alcoholic Beverages","Inclusion Criteria:\n\n* Adults ages 21 years and older\n* Consumed alcohol at least once in the last year\n* Able to complete a survey in English\n\nExclusion Criteria:\n\n\\- Not living in the US","99 Years",{"count":268,"type":21},1500,[24],"This study aims to examine the effects of marketing claims on alcoholic beverage packaging on alcohol consumers' perceptions and intentions. Participants will be randomized to view three images of alcoholic beverages (beer, hard seltzer, flavored malt beverage) with one of three marketing claims (or a no claim control), and then queried about their perceptions of the product and intentions to consume the product.",[29],"2026-06-22",{"date":274,"type":46},"2026-06-25",{"date":276,"type":46},"2025-10-10",{"date":278,"type":21},"2026-09-17",{"name":280,"class":53},"UNC Lineberger Comprehensive Cancer Center",{"id":282,"slug":283,"hasResults":12,"nctId":284,"briefTitle":285,"officialTitle":286,"acronym":287,"eligibilityCriteria":288,"healthyVolunteers":61,"sex":62,"minAge":18,"maxAge":4,"enrollmentInfo":289,"targetDuration":4,"studyType":22,"phases":291,"briefSummary":292,"conditions":293,"keywords":308,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":330,"lastUpdatePostDateStruct":331,"startDateStruct":332,"completionDateStruct":334,"leadSponsor":336,"locationsCount":119},"100643981","health-ahead-comparative-effectiveness-study-100643981","NCT07669168","Health Ahead Comparative Effectiveness Study","Health Ahead: Sequential Comparative-Effectiveness Studies Toward Automated, Universally Deployable Preventive Health Screening","HACE","Inclusion Criteria:\n\n* Age 18 years or older\n* Willing and able to provide written informed consent, or enrollment with consent of a legally authorized representative\n* Willing to participate in longitudinal follow-up.\n\nExclusion Criteria:\n\n\\- Age under 18 years.",{"count":290,"type":21},1000000,[24],"The Health Ahead Comparative Effectiveness Study is a pragmatic, parallel-arm interventional platform that systematically compares successive changes to preventive health screening - each isolated as a single variable against current practice - on the path toward a fully automated screening system deployable in any environment, including the most isolated and resource-limited communities. Each comparison is evaluated with a common set of engagement, behavior-change, experience, cost, and longitudinal outcome measures, allowing results to accumulate on a consistent yardstick across the life of the platform.\n\nThe first comparison evaluates static versus interactive personalized health report delivery. Subsequent pre-planned comparisons, added by protocol amendment, evaluate mobile community versus fixed laboratory screening; and a hybrid medical-droid plus human-delivery model versus human-only screening. All participants are simultaneously enrolled in the 100-Year Human Aging Study and the Human Observatory Study, contributing individual longitudinal and population-level causal inference data through those protocols.",[294,295,296,297,298,29,299,300,301,302,303,304,305,306,307],"Health Services Accessibility","Rural Health","Medically Underserved Area","Preventive Health Services","Patient Participation","Aging","Cardiovascular Diseases","Metabolic Syndrome","Cognitive Dysfunction","Frailty","Activities of Daily Living","Health Related Quality of Life","Health Equity","Telemedecine",[309,310,311,312,313,306,295,314,315,192,316,317,318,319,320,321,322,323,324,325,326,327,328,329],"Sequential Platform Trial","Interactive Health Report","Health Activation","Mobile Health Screening","Comparative Effectiveness","Medically Underserved","Preventive Medicine","Cardiopulmonary Exercise Testing","Body Composition","DEXA","Health Ahead Bus","Mobile Clinic","Automated Screening","Medical Droids","Biological Age","Healthspan","Longevity","Life Expectancy","Chronic Disease","Cost-Effectiveness","Health Services Research","2026-06-20",{"date":274,"type":46},{"date":333,"type":21},"2026-06-09",{"date":335,"type":21},"2099-12-31",{"name":337,"class":338},"William Brandenburg, MD","INDUSTRY",{"id":340,"slug":341,"hasResults":12,"nctId":342,"briefTitle":343,"officialTitle":344,"acronym":4,"eligibilityCriteria":345,"healthyVolunteers":12,"sex":62,"minAge":18,"maxAge":4,"enrollmentInfo":346,"targetDuration":4,"studyType":22,"phases":348,"briefSummary":349,"conditions":350,"keywords":355,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":357,"lastUpdatePostDateStruct":358,"startDateStruct":360,"completionDateStruct":362,"leadSponsor":364,"locationsCount":88},"100514906","personalized-health-self-management-training-for-colorectal-cancer-survivors-100514906","NCT05984589","Personalized Health Self-Management Training for Colorectal Cancer Survivors","A Prospective, Randomized, Controlled, Double-Arm Study of RISE (Re-Invent, Integrate, Strengthen, Expand) Personalized Self-Management Training (PSMT) Compared to Standardized Self-Management Training (SSMT) in Gastrointestinal Cancer (GI) Patients","Inclusion Criteria:\n\n* Age ≥18 years at the time of consent.\n* History of Stage I-IV colorectal cancer (CRC) or other gastrointestinal cancer within the past 10 years prior to enrollment.\n* Ability to speak, write, and read English sufficiently to allow for program participation.\n* Identified by self-report as having willingness and interest to work on at least one lifestyle-related risk factor. Lifestyle-related risk factors include diet, physical activity, body composition, alcohol use.\n* Scoring ≤3.5 on the World Cancer Research Fund\u002FAmerican Institute for Cancer Research (WCRF\u002FAICR) Health Behavior Adherence Scale or in the low-to-moderate range in any subcategory consistent with moderate to low adherence to healthy behavior recommendations (HBRs).\n* Ambulatory and independent in activities of daily living (ADL).\n* Written informed consent obtained from subject and ability for subject to comply with the requirements of the study.\n\nExclusion Criteria:\n\n* Cognitive or mental impairments that in the opinion of the Principal Investigator or study physician would hinder the program participation.",{"count":347,"type":21},120,[24],"This is a Phase 2 prospective, randomized, controlled, double-arm study to assess personalized self-management training (PSMT) intervention efficacy and patient experiences compared to standardized self-management training (SSMT). A total of 120 gastrointestinal (GI) cancer patients will be enrolled and randomized 1:1 to complete a 6-week self-management training program (either PSMT or SSMT) to be carried out by licensed occupational therapists with doctoral training.\n\nThis study aims to examine whether PSMT is more effective in increasing adherence to healthy behavior recommendations compared to SSMT in GI cancer patients.",[351,352,353,29,354],"Colorectal Cancer","Healthy Lifestyle","Behavior, Health","Gastrointestinal Cancers",[356],"self-management training","2026-06-08",{"date":359,"type":46},"2026-06-10",{"date":361,"type":46},"2024-03-01",{"date":363,"type":21},"2028-11-30",{"name":365,"class":53},"University of Southern California",{"id":367,"slug":368,"hasResults":12,"nctId":369,"briefTitle":370,"officialTitle":371,"acronym":372,"eligibilityCriteria":373,"healthyVolunteers":12,"sex":62,"minAge":211,"maxAge":64,"enrollmentInfo":374,"targetDuration":4,"studyType":22,"phases":376,"briefSummary":377,"conditions":378,"keywords":383,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":387,"lastUpdatePostDateStruct":388,"startDateStruct":390,"completionDateStruct":392,"leadSponsor":394,"locationsCount":119},"100636769","digitally-enhanced-cognitive-behavioral-therapy-100636769","NCT07569991","Digitally Enhanced Cognitive-Behavioral Therapy","Digitally Enhanced Cognitive-Behavioral Therapy for Adolescents With Depression and Obesity","CBT+","Inclusion Criteria:\n\n* Age 12-17 years\n* Body mass index (BMI) ≥85th percentile for age and sex\n* Elevated depression symptoms, Center for Epidemiologic Studies-Depression Scale (CES-D) ≥21\n\nExclusion Criteria:\n\n* Type 2 diabetes; Fasting glucose ≥126 mg\u002FdL or HbA1c ≥6.5\n* Major developmental (e.g., intellectual developmental disability) or medical or genetic condition (e.g. cancer, Bardet-Biedhl)\n* Pregnancy\u002Fbreastfeeding (females)\n* Bariatric surgery, weight loss medication, or weight loss \\>3% in the past 3 months\n* Active suicidality or self-harm",{"count":375,"type":21},60,[24],"Adolescent depression is a major public health problem. Depression affects adolescents' emotional well-being now and in the future, and it also affects their physical health, especially the risk for heart disease and other cardiovascular and metabolic health problems. In adolescents with depression and obesity, evidence-based programs for depression, like cognitive-behavioral therapy (CBT), might improve physical health, in part by supporting healthy behaviors such as physical activity, nutritious eating, and getting enough sleep. Our preliminary studies provide support for this overarching hypothesis. If adolescents have access to a digital app to support practicing CBT skills in between program sessions, it might especially help them to learn skills that help to feel better and be healthier in their day-to-day lives. We are tailoring a digital app for this purpose and we will make changes to the app based on feedback from adolescents, their parents, and their doctors. Once the app is well-liked and helpful, and works well as a support for taking part in CBT, we will randomly assign 60 adolescents with depression and overweight\u002Fobesity to either \"CBT+\" - a CBT group program plus the app, or \"CBT-only\" - the CBT group program only. We will pilot test whether this research is feasible, likeable, and credible, learning information that will inform a larger study to test of CBT+ can support emotional well-being, health behavior, and cardiovascular and metabolic health in adolescents.",[379,380,381,382,29],"Depression in Adolescence","Obesity & Overweight","Cognitive-behavioral Therapy","Mobile Health Technology (mHealth)",[384,385,223,386,34],"cognitive-behavioral therapy","depression","cardiometabolic health","2026-06-03",{"date":389,"type":46},"2026-06-05",{"date":391,"type":21},"2027-01-01",{"date":393,"type":21},"2028-08-01",{"name":395,"class":53},"Colorado State University",{"id":397,"slug":398,"hasResults":12,"nctId":399,"briefTitle":400,"officialTitle":401,"acronym":4,"eligibilityCriteria":402,"healthyVolunteers":12,"sex":62,"minAge":18,"maxAge":4,"enrollmentInfo":403,"targetDuration":4,"studyType":22,"phases":405,"briefSummary":406,"conditions":407,"keywords":408,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":428,"lastUpdatePostDateStruct":429,"startDateStruct":431,"completionDateStruct":432,"leadSponsor":434,"locationsCount":119},"100639482","simplifying-diet-tracking-in-a-digital-weight-loss-intervention-100639482","NCT07601061","Simplifying Diet Tracking in a Digital Weight Loss Intervention","Simplifying Dietary Self-Monitoring in a Digital Weight Loss Intervention","Inclusion Criteria:\n\n* adults (ages 18+ years)\n* body mass index (BMI) 25.0 to 45.0 kg\u002Fm\\^2\n* smartphone ownership\n* willing to install a mobile app on personal smartphone\n* access to a personal email account\n* English or Spanish language proficiency\n* interest in losing weight through behavioral strategies\n* living in the United States\n* willing to be randomized\n\nExclusion Criteria:\n\n* concurrent enrollment in another weight management intervention\n* loss of ≥5% weight in the past 6 months\n* prior or planned bariatric surgery during the trial period\n* current or planned pregnancy during the trial period, or recent pregnancy in the past 6 months\n* currently breastfeeding or lactating\n* current use of anti-obesity medications\n* living with someone else participating in the study\n* hospitalization for a mental health condition in the past 12 months\n* inability to engage in moderate forms of physical activity akin to brisk walking\n* medical or psychiatric contraindication (e.g., end stage renal disease, cancer, schizophrenia, dementia, use of steroids, use of antipsychotic medication)\n* if an individual would be better suited for a more intensive or different type of intervention based on a health condition (e.g., individuals with history of an eating disorder or cardiovascular event, uncontrolled hypertension, or uncontrolled diabetes mellitus)\n* investigator discretion for safety reasons",{"count":404,"type":21},328,[24],"The purpose of this study is to compare two approaches for tracking dietary intake in a 12-month fully digital weight loss intervention: (1) Simplified approach: track Red Zone Foods (e.g., foods high in calories and low in nutritional value) vs. (2) Detailed approach: track all foods and their corresponding calories. In essence, this is a head-to-head comparison of two tracking approaches; the investigators are evaluating whether weight loss is comparable over 12 months, or whether one approach will have greater weight loss.\n\nThe investigators will recruit 328 adults. Broadly, adults with overweight or obesity who live in the United States will be eligible. The weight loss intervention will last 12 months. All participants will be asked to track their dietary intake + body weight + steps daily as well as complete weekly behavioral lessons and action plans to promote healthy eating and physical activity. All study tasks will occur remotely. Assessment of body weight and survey measures will occur at the beginning of the trial (\"baseline\"), and at 1, 6, 12, and 18 months.",[133,132,134,29,135],[158,409,146,137,410,138,411,412,413,414,415,416,417,149,145,139,418,147,154,419,420,421,422,423,424,425,426,157,163,156,155,159,160,427],"behavioral intervention","body weight","BMI","diet","tracking","track","self-monitoring","self-monitor","lifestyle","weight loss intervention","red zone foods","calorie counting","noninferiority trial","non-inferiority","comparative effectiveness trial","comparative effectiveness","RCT","randomized clinical trial","standalone","2026-05-22",{"date":430,"type":46},"2026-05-28",{"date":199,"type":21},{"date":433,"type":21},"2030-10-31",{"name":174,"class":53},{"id":436,"slug":437,"hasResults":12,"nctId":438,"briefTitle":439,"officialTitle":440,"acronym":441,"eligibilityCriteria":442,"healthyVolunteers":61,"sex":62,"minAge":443,"maxAge":444,"enrollmentInfo":445,"targetDuration":4,"studyType":214,"phases":4,"briefSummary":446,"conditions":447,"keywords":453,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":472,"lastUpdatePostDateStruct":473,"startDateStruct":475,"completionDateStruct":477,"leadSponsor":479,"locationsCount":4},"100639073","meva-cognitive-wellness-platform-study-for-adults-100639073","NCT07595250","MEVA Cognitive Wellness Platform Study for Adults","Phase 1 Validation Study of the MEVA Cognitive Wellness Platform","MEVA","Inclusion Criteria:\n\n* Adults aged 55 to 75 years\n* Community-dwelling (living independently in the community)\n* English fluency sufficient for informed consent, task instructions, and questionnaires\n* Able to provide informed consent using teach-back method\n* Able to use a computer or tablet for simple tap or drag interactions\n* Functional vision sufficient for on-screen tasks with usual corrective lenses\n* Functional hearing sufficient for spoken instructions with or without hearing aids\n* Interest in cognitive wellness and personal well-being\n* Available for baseline visit and possible retest visit approximately 14 days later\n* Transportation to study site or ability to participate remotely if permitted by protocol\n* Assistive devices and accommodations are permitted\n\nExclusion Criteria:\n\n* Severe visual impairment preventing completion of digital tasks\n* Severe motor impairment preventing interaction with tablet or web application\n* Known diagnosis of moderate or severe dementia, or inability to comprehend consent and task instructions\n* Current participation in another cognitive training or technology intervention study likely to confound outcomes\n* Recent hospitalization, emergency room visit, or acute exacerbation of a medical or psychiatric condition within the past 30 days that would impede study participation\n* Current substance use disorder likely to interfere with study adherence or completion\n* Recent intensive use of a similar structured cognitive wellness or brain training application","55 Years","75 Years",{"count":100,"type":21},"The goal of this observational study is to evaluate the reliability, usability, and feasibility of the MEVA Cognitive Wellness Platform in community-dwelling adults aged 55 to 75.\n\nThe main questions it aims to answer are:\n\nHow consistent is the MEVA Global Cognitive Index when participants complete the MEVA activities again approximately 14 days later? How usable and acceptable is the MEVA platform for older adults in community settings? What completion rates, data quality patterns, and participant feedback are observed during use of the platform?\n\nParticipants will:\n\nComplete a baseline study visit lasting approximately 45 to 60 minutes Complete a 7-activity digital cognitive wellness battery Answer questionnaires about usability, technology acceptance, and wellness experience Complete the Saint Louis University Mental Status (SLUMS) examination as an exploratory comparison measure If selected for the retest group, return approximately 14 days later to complete the MEVA activities again\n\nMEVA is being evaluated as a cognitive wellness platform. It is not intended to diagnose, treat, prevent, screen for, or monitor any disease or medical condition.",[448,449,450,299,451,29,452],"Cognitive Wellness","Healthy Aging","Age-Related Cognitive Change","Cognitive Change","Primary Care",[454,455,456,457,458,459,460,461,462,463,464,465,466,467,468,469,470,471],"Cognitive wellness","Healthy aging","Health equity","Test-retest reliability","Community-dwelling older adults","Primary care","Digital wellness","Older adult engagement","Psychometrics","Usability","Community health","Wellness tracking","Cognitive engagement","Adult development","General wellness","Montessori-informed activities","Technology acceptance","Exploratory convergent validity","2026-05-18",{"date":474,"type":46},"2026-05-20",{"date":476,"type":21},"2026-05",{"date":478,"type":21},"2026-12",{"name":480,"class":338},"Mentage LLC",{"id":482,"slug":483,"hasResults":12,"nctId":484,"briefTitle":485,"officialTitle":485,"acronym":4,"eligibilityCriteria":486,"healthyVolunteers":61,"sex":62,"minAge":487,"maxAge":4,"enrollmentInfo":488,"targetDuration":4,"studyType":22,"phases":490,"briefSummary":491,"conditions":492,"keywords":4,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":497,"lastUpdatePostDateStruct":498,"startDateStruct":500,"completionDateStruct":501,"leadSponsor":503,"locationsCount":119},"100640256","development-of-a-chatbot-supported-personalized-exercise-program-for-older-adults-and-evaluation-of-its-effects-on-cognitive-functions-100640256","NCT07596082","Development of a Chatbot-supported Personalized Exercise Program for Older Adults and Evaluation of Its Effects on Cognitive Functions","Inclusion Criteria:\n\n* Aged 65 years and older\n* Normal or mildly impaired cognitive status\n* Medical condition that does not prevent participation in physical activity\n* Ability to use a smartphone or tablet (for chatbot access)\n* Voluntary participation\n\nExclusion Criteria:\n\n* Moderate to severe dementia\n* Severe depression or serious psychiatric disorders\n* Acute cardiovascular risk\n* Communication difficulties due to significant hearing or visual impairment\n* Regular engagement in structured exercise within the past 6 months (participants in the maintenance phase of exercise behavior)","65 Years",{"count":489,"type":21},90,[24],"The purpose of this study is to develop an artificial intelligence-based chatbot application to support exercise behavior in individuals aged 60 and over who do not regularly exercise, and to evaluate its effectiveness. In addition, the study aims to examine the effects of changes in exercise habits on the cognitive (mental) functions of older adults.\n\nIn this study, the impact of a chatbot-supported personalized exercise program on cognitive functions in older individuals will be evaluated. A total of 90 participants is planned for inclusion in this study.\n\nIf you agree to participate in this study, depending on the group you are assigned to, you may receive:\n\n* An artificial intelligence-based chatbot program, along with educational materials about the importance of exercise, or\n* Only educational materials (brochures) prepared by the researchers about the importance of exercise.\n\nAt the beginning of the study, you will be asked to complete a data collection form. The same form will also be administered at week 12 and week 24.\n\nThis form will include:\n\n* Basic information such as your age and gender,\n* Questions about your exercise habits,\n* A brief test to assess your cognitive (mental) functions,\n* Questions evaluating your level of physical activity. The study duration is 24 weeks, including 12 weeks of intervention and 12 weeks of follow-up.",[493,494,495,496,29],"Aged","Exercise","Cognition","Artificial Intelligence (AI)","2026-05-12",{"date":499,"type":46},"2026-05-19",{"date":166,"type":21},{"date":502,"type":21},"2026-10-30",{"name":504,"class":53},"Dokuz Eylul University",{"id":506,"slug":507,"hasResults":12,"nctId":508,"briefTitle":509,"officialTitle":510,"acronym":4,"eligibilityCriteria":511,"healthyVolunteers":12,"sex":62,"minAge":18,"maxAge":4,"enrollmentInfo":512,"targetDuration":4,"studyType":22,"phases":514,"briefSummary":515,"conditions":516,"keywords":517,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":520,"lastUpdatePostDateStruct":521,"startDateStruct":523,"completionDateStruct":525,"leadSponsor":527,"locationsCount":88},"100571574","ccsh-compassion-centered-spiritual-health-for-teams-100571574","NCT06722027","CCSH (Compassion-Centered Spiritual Health) for Teams","Compassion-Centered Spiritual Health Interventions for Teams (CCSH-TI) With Faculty and Staff","Inclusion Criteria:\n\n* Full-time employees working in oncology teams at Winship Cancer Institute;\n* Employees working in intensive care at Emory University St. Joseph hospital.\n\nExclusion Criteria:\n\n* Less than 18 years old",{"count":513,"type":21},80,[24],"Emory Spiritual Health has developed a Compassion-Centered Spiritual Health group-based intervention, called CCSH Interventions for Teams, and are enrolling staff and providers into the groups in this randomized study design. The groups will meet once every other week for 60 minutes for 8 weeks (4 sessions total).\n\nThe investigators will evaluate the feasibility and acceptability of this novel team-based intervention that includes mindfulness and compassion-based approaches with mixed-role oncology teams. Employees (n = 80; nurses, advanced practice providers (APPs), physicians, staff) working at an NCI- designated Comprehensive Cancer Center will be randomized by team (8-12 employees\u002Fgroup) to Compassion Centered Spiritual Health Team Intervention (CCSH-TI) or TAU (Treatment as Usual) group. The research objective is to evaluate the feasibility and acceptability of CCSH-TI, and to develop and validate a novel, low-burden ambulatory assessment \"toolkit\" to improve the measurement of psychological safety and burnout.",[29],[518,519],"Behavioral Intervention","Healthcare provider burnout","2026-04-30",{"date":522,"type":46},"2026-05-05",{"date":524,"type":46},"2025-09-24",{"date":526,"type":21},"2026-11-30",{"name":528,"class":53},"Emory University",{"id":530,"slug":531,"hasResults":12,"nctId":532,"briefTitle":533,"officialTitle":534,"acronym":535,"eligibilityCriteria":536,"healthyVolunteers":61,"sex":62,"minAge":18,"maxAge":4,"enrollmentInfo":537,"targetDuration":4,"studyType":214,"phases":4,"briefSummary":539,"conditions":540,"keywords":555,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":570,"lastUpdatePostDateStruct":571,"startDateStruct":573,"completionDateStruct":575,"leadSponsor":577,"locationsCount":88},"100585203","health-surveillance-at-constructor-university-bremen-cub-and-among-haw-hamburg-employees-100585203","NCT06899308","Health Surveillance at Constructor University Bremen (CUB) and Among HAW-Hamburg Employees","Health Surveillance at Constructor University Bremen (CUB) to Assess Students' and HAW-Hamburg Employees' Health and Wellbeing - Explanatory Sequential Mixed-Methods Approach","CUB-HS2025","Inclusion Criteria:\n\n* English language skills\n* Reading and writing skills\n* Internet access\n* Student status\n* Consent to participate in the study\n\nExclusion Criteria:\n\n* Illiteracy\n* Massively limited cognitive abilities ( i.e. linguistic components of the digital offerings must be able to be used, and questionnaires completed, or interviews participated in) and severe psychiatric disorders (e.g., severe depression)",{"count":538,"type":21},363,"The aim of Health Surveillance is to analyze and describe the state of health of students at Constructor University, key influencing factors and individual resources by using mixed-method design.",[541,542,543,29,544,545,546,547,548,549,550,551,552,553,554],"Social Isolation or Loneliness","Anxiety","Anxiety Depression (Mild or Not Persistent)","Observational Study","Stress, Psychological","Emotional Stress","Life Stress","Psychological Stress","Stress, Emotional","Stress (Psychology)","Substance Abuse","Substance Addiction","Substance Dependence","Substance Use",[556,557,558,559,560,561,562,563,564,565,566,567,568,569],"Healthy students","Health literacy","Disability","Age","Gender","Study characteristics","PHQ-4","Self-efficacy","Satisfaction with Life Scale (SWLS)","Subjective health status","Student satisfaction","UCLA-LS","HEI-Stress","Mixed Method","2026-04-25",{"date":572,"type":46},"2026-05-01",{"date":574,"type":46},"2025-03-17",{"date":576,"type":21},"2026-12-31",{"name":578,"class":53},"Jacobs University Bremen gGmbH",{"id":580,"slug":581,"hasResults":12,"nctId":582,"briefTitle":583,"officialTitle":584,"acronym":4,"eligibilityCriteria":585,"healthyVolunteers":12,"sex":62,"minAge":97,"maxAge":4,"enrollmentInfo":586,"targetDuration":4,"studyType":22,"phases":588,"briefSummary":589,"conditions":590,"keywords":4,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":591,"lastUpdatePostDateStruct":592,"startDateStruct":594,"completionDateStruct":596,"leadSponsor":598,"locationsCount":119},"100628205","unc-tobacco-convenience-store-100628205","NCT07458607","UNC Tobacco Convenience Store","UNC Tobacco Convenience Store Study","Inclusion Criteria:\n\n* Are ages 21 years and older\n* Smoke cigarettes currently (i.e. currently smoke some days or every day and have smoked at least 100 cigarettes in their lifetime)\n* Smoke menthol cigarettes\n* Purchased menthol cigarettes in a store in the past month\n* Read and speak English\n* Can complete a survey on a computer without help\n* Can receive images by text message\n* Can attend 2 in-person appointments involving shopping tasks and computer surveys\n\nExclusion Criteria:\n\n* Are pregnant\n* Are breastfeeding\n* Enrolled currently in another research study about quitting smoking",{"count":587,"type":21},1185,[24],"The main purpose of this trial is to evaluate the impact of a menthol cigarette ban accompanied by a quit smoking campaign on tobacco purchasing behavior. Investigators will conduct a randomized clinical trial with \\~1,185 US adults (ages 21+ years) who currently smoke menthol cigarettes.",[29],"2026-04-23",{"date":593,"type":46},"2026-04-27",{"date":595,"type":46},"2026-04-20",{"date":597,"type":21},"2028-04",{"name":599,"class":53},"University of North Carolina, Chapel Hill",{"id":601,"slug":602,"hasResults":12,"nctId":603,"briefTitle":604,"officialTitle":605,"acronym":4,"eligibilityCriteria":606,"healthyVolunteers":61,"sex":62,"minAge":18,"maxAge":266,"enrollmentInfo":607,"targetDuration":4,"studyType":22,"phases":609,"briefSummary":610,"conditions":611,"keywords":613,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":624,"lastUpdatePostDateStruct":625,"startDateStruct":627,"completionDateStruct":629,"leadSponsor":631,"locationsCount":119},"100469833","the-validation-study-of-bioelectronics-100469833","NCT05397951","The Validation Study of Bioelectronics","Evaluation of Wearable Multi-modality Sensors for Monitoring Vital Signs","Inclusion Criteria:\n\n* Individuals with ages between 18 and 99.\n* Healthy individuals (not known to suffer any significant illness relevant to the proposed study).\n\nExclusion Criteria:\n\n* Pregnant or lactating.\n* History of active (clinically significant) skin disorders that make skin vulnerable to contact conventional electronic devices.\n* History of allergic response to silicones or adhesives (such as 3M Tegaderm).\n* Broken, damaged or irritated skin or rashes near the sensor application sites (finger, wrist, temple, subclavian, arm, neck, and thigh).\n* Subjects who are physically or cognitively unable to normally perform activities of daily living, assessed at the discretion of the investigator to ensure safe completion of study tasks.\n* Subjects who are unable to participate in moderate exercise for 6 minutes.",{"count":608,"type":21},22,[24],"The purpose of this study is to investigate the safe wearability and basic functions of the multi-modality sensors fabricated in the PI lab.",[612,29],"Healthy",[614,615,616,617,618,619,620,621,622,623],"sensor","non-invasive","multi-modality","vital signs","safe wearability","optoelectronic system","optical polarimetry","near-infrared spectroscopy","skin-interfaced","wearable","2026-04-15",{"date":626,"type":46},"2026-04-17",{"date":628,"type":46},"2024-01-09",{"date":630,"type":21},"2026-11",{"name":599,"class":53},{"id":633,"slug":634,"hasResults":12,"nctId":635,"briefTitle":636,"officialTitle":636,"acronym":4,"eligibilityCriteria":637,"healthyVolunteers":12,"sex":62,"minAge":443,"maxAge":638,"enrollmentInfo":639,"targetDuration":4,"studyType":22,"phases":641,"briefSummary":642,"conditions":643,"keywords":4,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":651,"lastUpdatePostDateStruct":652,"startDateStruct":653,"completionDateStruct":655,"leadSponsor":657,"locationsCount":119},"100634461","evaluation-of-a-novel-indoor-air-pollution-intervention-among-older-adults-100634461","NCT07539987","Evaluation of a Novel Indoor Air Pollution Intervention Among Older Adults","Inclusion Criteria:\n\n* 55-79 years of age one primary residence (5+ days per week)\n* have an electronic device, email address, and reliable internet at home for survey submission\n\nExclusion Criteria:\n\n* current smoking of any kind or living in a household with someone who currently smokes\n* current use of a portable air cleaner unit at home\n* plans to move in the next year\n* previous physician-diagnosed cardiovascular disease (coronary heart disease \\[myocardial infarction\\], stroke, or heart failure)","79 Years",{"count":640,"type":21},154,[24],"Particulate matter air pollution is the leading environmental risk factor of cardiovascular disease and is increasing in the Western United States due to more frequent and severe wildfires. Older adults are particularly susceptible to both air pollution exposures and the development of cardiovascular disease, and the older adult population in the United States is rapidly growing. Given the converging threats of worsening air quality and an aging population, this clinical trial will evaluate a novel, multifaceted indoor air quality intervention to improve cardiovascular health outcomes among older adults in the wildfire-impacted state of Montana.",[300,644,645,646,647,648,649,650,29],"Blood Pressure","Glycated Hemoglobin (HbA1c)","Cholesterol","Cholesterol, HDL","Cholesterol, LDL","Indoor Air Quality","Particulate Matter","2026-04-13",{"date":595,"type":46},{"date":654,"type":21},"2026-08",{"date":656,"type":21},"2030-07",{"name":658,"class":53},"University of Montana",{"id":660,"slug":661,"hasResults":12,"nctId":662,"briefTitle":663,"officialTitle":664,"acronym":4,"eligibilityCriteria":665,"healthyVolunteers":61,"sex":62,"minAge":18,"maxAge":4,"enrollmentInfo":666,"targetDuration":4,"studyType":214,"phases":4,"briefSummary":668,"conditions":669,"keywords":4,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":671,"lastUpdatePostDateStruct":672,"startDateStruct":673,"completionDateStruct":675,"leadSponsor":676,"locationsCount":119},"100633865","survey-of-knowledge-practice-and-recommendation-behaviors-regarding-healthy-lifestyles-among-healthcare-workers-100633865","NCT07532239","Survey of Knowledge, Practice, and Recommendation Behaviors Regarding Healthy Lifestyles Among Healthcare Workers","Investigation of Healthy Lifestyle Knowledge, Practice, and Recommendation Behaviors Among Healthcare Workers Across Different Levels of Healthcare Institutions","Inclusion Criteria:\n\n* Healthcare workers employed at participating healthcare institutions\n\nExclusion Criteria:\n\n* Individuals unwilling or unable to provide informed consent",{"count":667,"type":21},150,"This cross-sectional observational study aims to assess healthy lifestyle knowledge, personal health practices, and lifestyle recommendation behaviors among healthcare workers across different levels of healthcare institutions. The study will also collect clinical examination and biochemical indicators to evaluate the health status of participants and explore their associations with lifestyle-related knowledge and behaviors.\n\nHealthcare workers play a critical role in promoting healthy lifestyles among patients; however, their own health behaviors and recommendations may vary depending on training background and institutional settings. This study seeks to better understand these differences and identify potential gaps between knowledge and practice.\n\nThe findings of this study may help inform targeted training strategies and support the development of effective health promotion programs for healthcare professionals, ultimately improving the quality of lifestyle guidance provided to patients.",[352,670,29],"Health Knowledge","2026-04-08",{"date":624,"type":46},{"date":674,"type":21},"2026-04-10",{"date":595,"type":21},{"name":677,"class":53},"Jiangsu Taizhou People's Hospital",{"id":679,"slug":680,"hasResults":12,"nctId":681,"briefTitle":682,"officialTitle":682,"acronym":4,"eligibilityCriteria":683,"healthyVolunteers":61,"sex":62,"minAge":684,"maxAge":4,"enrollmentInfo":685,"targetDuration":4,"studyType":22,"phases":687,"briefSummary":688,"conditions":689,"keywords":690,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":698,"lastUpdatePostDateStruct":699,"startDateStruct":701,"completionDateStruct":703,"leadSponsor":705,"locationsCount":119},"100577222","families-in-balance-enhancing-household-routines-and-reducing-early-childhood-obesity-among-families-with-low-income-100577222","NCT06795490","Families in Balance: Enhancing Household Routines and Reducing Early Childhood Obesity Among Families With Low-income","Inclusion Criteria:\n\n* Parents must be the legal and custodial guardian of a 2 through 5-year-old child\n* Parents must report that their child is eligible for public health insurance\n* Parents must be able to complete the study activities in English\n* Parents must be able to complete study activities at a study location or at home, and online\u002Fvia Zoom.\n\nExclusion Criteria:\n\n\\- Children must not have serious medical problems that affect weight, sleep, activity, or eating.","2 Years",{"count":686,"type":21},300,[24],"This study will evaluate the effects of two different approaches to support healthy family mealtime, sleep, and screentime routines: A parent leader-guided online program that promotes parent and child self-regulation as a means to improve healthy family routines versus an asynchronous program that provides parents information about healthy family routines. Families will be randomly assigned to either of these programs and changes in parent and child outcomes will be evaluated.",[29],[691,692,693,694,695,696,697],"Online program","Informational material","Surveys","Eating activity","Sleep","Health behaviors","Body mass index","2026-04-02",{"date":700,"type":46},"2026-04-06",{"date":702,"type":46},"2025-03-31",{"date":704,"type":21},"2027-02",{"name":706,"class":53},"University of Michigan",{"id":708,"slug":709,"hasResults":12,"nctId":710,"briefTitle":711,"officialTitle":711,"acronym":4,"eligibilityCriteria":712,"healthyVolunteers":61,"sex":62,"minAge":18,"maxAge":4,"enrollmentInfo":713,"targetDuration":4,"studyType":22,"phases":715,"briefSummary":716,"conditions":717,"keywords":4,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":722,"lastUpdatePostDateStruct":723,"startDateStruct":725,"completionDateStruct":727,"leadSponsor":728,"locationsCount":88},"100612078","the-effect-of-a-transtheoretical-model-based-educational-intervention-on-first-year-nursing-students-hpv-knowledge-health-beliefs-and-vaccination-behavior-intentions-100612078","NCT07248904","The Effect of a Transtheoretical Model-Based Educational Intervention on First-Year Nursing Students' HPV Knowledge, Health Beliefs, and Vaccination Behavior Intentions","Inclusion Criteria:\n\n* First-year students enrolled in the Nursing Department of the Faculty of Health Sciences\n* Provide written informed consent to participate\n* Agree to attend all educational sessions and data collection appointments during the study period\n* Have sufficient Turkish literacy to read and understand study materials\n* Have not previously received any comprehensive education about HPV infection or HPV vaccination\n\nExclusion Criteria:\n\n* Students who do not agree to participate in the study\n* Students who do not provide written informed consent",{"count":714,"type":21},88,[24],"The purpose of this study is to examine the impact of a structured educational program based on the Transtheoretical Model (TTM) on HPV knowledge, health beliefs, and vaccination behavioral intentions among first-year nursing students. The study will also evaluate how the intervention affects students' HPV vaccine readiness compared to the TTM.\n\nThe primary questions addressed by the study are:\n\n* Does the TTM-based educational intervention increase students' knowledge about HPV and the HPV vaccine?\n* Does the program change students' health beliefs regarding susceptibility, severity, benefits, and barriers to HPV and the HPV vaccine?\n* Does the program improve students' intentions and readiness to receive the HPV vaccine?\n* Do students move to a higher behavioral readiness stage (from Precontemplation to Contemplation, Preparation, Action, or Maintenance) after the intervention?\n\nThe researcher will compare the TTM-based educational intervention with a control group that did not receive structured education to determine whether a personalized, stage-based approach is more effective in improving HPV-related outcomes among nursing students.\n\nParticipants will:\n\n* Complete baseline questionnaires measuring HPV knowledge, health beliefs, and vaccination intention.\n* The experimental group (intervention group) will receive personalized TTM-based education, face-to-face instruction in modules aligned with the five TTM phases (Precontemplation, Contemplation, Preparation, Action, and Maintenance).\n* The experimental group will participate in educational sessions designed to raise awareness, correct misinformation, support decision-making, and encourage protective behaviors.\n* The control group will not receive any educational program.\n* All participants in the experimental and control groups will complete the same questionnaires again to assess changes after the intervention.\n\nThe TTM-based educational intervention provides:\n\n* Staged counseling\n* Information about HPV and the HPV vaccine\n* Activities to raise awareness, strengthen motivation, and support vaccination adoption\n* Personalized feedback based on student readiness\n* Structured modules focusing on knowledge, belief, and behavior change strategies\n\nThe study population included first-year nursing students enrolled in the Faculty of Health Sciences. A total of 88 participants will be recruited and randomly assigned to either the intervention (n=44) or control (n=44) groups through simple randomization.\n\nThe results of this study are expected to contribute to the development of evidence-based education strategies in nursing, support of behavioral change models in health education, and strengthen the role of future nurses in HPV prevention, vaccine advocacy, and public health practice.",[718,719,720,721,29],"Human Papillomavirus (HPV)","Papillomavirus Vaccines","Health Knowledge, Attitudes, Practice","Students, Nursing","2026-03-26",{"date":724,"type":46},"2026-03-27",{"date":726,"type":46},"2026-01-16",{"date":520,"type":21},{"name":729,"class":53},"Cukurova University",{"id":731,"slug":732,"hasResults":12,"nctId":733,"briefTitle":734,"officialTitle":735,"acronym":4,"eligibilityCriteria":736,"healthyVolunteers":61,"sex":62,"minAge":211,"maxAge":737,"enrollmentInfo":738,"targetDuration":4,"studyType":22,"phases":740,"briefSummary":741,"conditions":742,"keywords":745,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":750,"lastUpdatePostDateStruct":751,"startDateStruct":753,"completionDateStruct":755,"leadSponsor":756,"locationsCount":119},"100568481","workshops-based-on-protection-motivation-theory-and-climate-change-100568481","NCT06681792","Workshops Based on Protection Motivation Theory and Climate Change","The Effect of Climate Change Workshops Based on Protection Motivation Theory on Middle School Students' Climate Change Awareness, Environmental Awareness, and Eco-Friendly Behaviors: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Being 12-13 years old and attend the school where the study is being conducted,\n* Voluntarily agree to take part in the research,\n* Consent from the student's family to participate in the study,\n\nExclusion Criteria:\n\n\\* If the pupil has an allergy to plants or grass.","13 Years",{"count":739,"type":21},66,[24],"\"This study aims to evaluate the impact of climate change workshops grounded in Protection Motivation Theory (PMT) on students' climate change awareness, environmental consciousness, and pro-environmental behaviors. The primary objective is to foster awareness, environmental literacy, and sustainable behavioral shifts among middle school students, thereby empowering them to adopt eco-friendly practices to mitigate the effects of climate change.\n\nNote on Protocol Revision: Due to cognitive suitability concerns identified during the pilot phase, the target population was shifted from primary to middle school students following expert consultation. This shift necessitated modifications to certain assessment instruments. These revisions have been approved by the ethics committee, and a new ethics approval number has been issued (Date of first protocol entry: July,2024).",[29,743,744],"Climate Change","Students",[746,747,743,748,749],"Protection Motivation Theory","Primary School Students","Awareness","Eco-friendly behavior","2026-03-20",{"date":752,"type":46},"2026-03-25",{"date":754,"type":46},"2026-02-18",{"date":231,"type":21},{"name":757,"class":53},"Selcuk University",{"id":759,"slug":760,"hasResults":12,"nctId":761,"briefTitle":762,"officialTitle":762,"acronym":4,"eligibilityCriteria":763,"healthyVolunteers":12,"sex":17,"minAge":764,"maxAge":765,"enrollmentInfo":766,"targetDuration":4,"studyType":22,"phases":768,"briefSummary":769,"conditions":770,"keywords":774,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":781,"lastUpdatePostDateStruct":782,"startDateStruct":784,"completionDateStruct":785,"leadSponsor":787,"locationsCount":119},"100628354","improving-health-among-disadvantaged-girls-to-slow-pubertal-onset-and-reduce-long-term-health-risks-100628354","NCT07460544","Improving Health Among Disadvantaged Girls to Slow Pubertal Onset and Reduce Long-term Health Risks","Inclusion Criteria:\n\n1. Child female biological sex\n2. Child BMI percentile in the overweight\u002Fobese range (BMI percentile ≥85th for age and sex)\n3. Low child household income based on local income requirements for subsidized housing\n4. At least 50% enrollment of child Black or Latina or 'multiple' race or ethnicity identification (self- or mother-identified)\n5. Child between ages 6.5 and 8.0 years at screening\n6. Participation of child with mother who identifies as a primary caregiver\n7. Confirmed child prepubertal status by mother-report on the indicated pubertal staging scale\n8. Child and mother speak English\n9. Successful completion of the 'run-in' protocol, which includes screening and the baseline assessment\n\nExclusion Criteria:\n\n1. Child has medical contraindications to participate in a weight loss program (e.g., chromosomal abnormality, phenylketonuria, syndromal cause of obesity, type 1 diabetes) as determined by child's pediatrician or study pediatrician\n2. Mother has major medical or psychiatric conditions likely to interfere with participation (e.g., dementia, schizophrenia, terminal illness with life expectancy \\\u003C12 months)\n3. Family lives in temporary or group housing or has plans to relocate outside the Seattle metropolitan area in the next 12 months","6 Years","8 Years",{"count":767,"type":21},240,[24],"This study is testing whether improving health in girls during the prepubertal period may slow the onset of puberty. This study will focus on prepubertal girls who have a high weight status (at or above the 85th percentile for body mass index). Half of the girls who join the study will participate in a treatment program to reduce weight and improve lifestyle behaviors, and half of the girls will participate in a control condition. The frequency of pubertal onset will be compared across the groups. This research is important because girls who experience puberty at an earlier age are at risk for poor psychological and physical health.\n\nGirls in the treatment condition will participate in the Family Based Treatment (FBT) program, an established treatment for children who are overweight or obese. Families attend 20 weekly sessions (30 minutes each) over a 5-month period. Sessions are led by a trained interventionist and focus on healthy eating and physical activity behaviors.\n\nGirls in the control condition will receive their usual medical care through their pediatric care doctor or other care provider. Families will also receive educational handouts about 1 time per month, addressing topics related to healthy eating and physical activity behaviors.\n\nFamilies in both the treatment and control conditions will participate in assessments conducted at baseline and approximately 6-, 12-, 18-, 24-, 30-, and 36 months follow-up. These assessments are led by a data collector and include the measurement of height and weight, pubertal status, and health behaviors.",[771,772,29,773],"Overweight\u002FObesity","Puberty","Cardiometabolic Health",[137,138,775,776,777,409,778,386,779,780,139],"puberty","pubertal onset","pubertal development","family-based treatment","health behaviors","health behavior change","2026-03-03",{"date":783,"type":46},"2026-03-10",{"date":476,"type":21},{"date":786,"type":21},"2030-06",{"name":788,"class":53},"University of Washington",{"id":790,"slug":791,"hasResults":12,"nctId":792,"briefTitle":793,"officialTitle":793,"acronym":4,"eligibilityCriteria":794,"healthyVolunteers":61,"sex":62,"minAge":18,"maxAge":266,"enrollmentInfo":795,"targetDuration":4,"studyType":22,"phases":797,"briefSummary":798,"conditions":799,"keywords":4,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":804,"lastUpdatePostDateStruct":805,"startDateStruct":807,"completionDateStruct":809,"leadSponsor":811,"locationsCount":202},"100548189","dime-la-verdad-verify-debunk-and-disseminate-100548189","NCT06417762","Dime La VerDAD: Verify, Debunk, and Disseminate","Inclusion Criteria:\n\n1. 18 years or older\n2. Fluent in English or Spanish\n3. Provide services as a community health worker or similar designation in at least one of the seven communities with high morbidity and mortality due to respiratory virus infections\n4. Have a social media presence (personal or work related)\n\nExclusion Criteria:\n\n1. Plan to stop working as a community health worker or similar designation before spring of 2028 (end of data collection planned)\n2. Do not wish to participate in a social media campaign",{"count":796,"type":21},1400,[24],"Dime la Verdad (Tell me the truth) will evaluate the use of storytelling by community health workers as a communication strategy to disseminate reliable health information on social media and encourage informed decision-making in favor of recommended immunizations in communities with high morbidity and mortality due to respiratory virus infections.\n\nDime La Verdad is an innovative social media capacity-building program based on theoretical frameworks related to health communication that empowers community health workers to disseminate reliable information about respiratory virus protection strategies through the use of personal narratives on social media. The proposed work will use a rigorous stepped wedge design to 1) deliver a scalable program of science communicators using an adapted curriculum grounded in principles of health communication, 2) evaluate how diffusion of health messaging is perceived on social media, and 3) discern how use of personal narratives to enhance science communication can encourage informed decision-making to promote evidence-based immunization practices and improve health outcomes.",[800,801,802,29,803],"Influenza","COVID-19","Communication Research","Respiratory Viral Infection","2026-02-26",{"date":806,"type":46},"2026-03-02",{"date":808,"type":46},"2024-07-02",{"date":810,"type":21},"2029-04-01",{"name":812,"class":53},"University of Chicago"]