[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hearing-loss-bilateral\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hearing-loss-bilateral":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,47,85,120,142,164],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100652498","hearing-intervention-effects-on-brain-and-language-development-in-children-with-bilateral-mild-hearing-loss-100652498",false,"NCT07774728","Hearing Intervention Effects on Brain and Language Development in Children With Bilateral Mild Hearing Loss","Effects of Hearing Aid Intervention on Brain and Language Development in Children With Bilateral Mild Hearing Loss: A Multicenter Randomized Controlled Trial","HBD-RCT","Inclusion Criteria:\n\n* Age: ≥0.5 years and \\\u003C4 years\n* Diagnosed with bilateral mild sensorineural hearing loss by objective hearing tests: bilateral click-ABR ≥35 dB nHL and ≤50 dB nHL, with bilateral type A tympanogram (including As\u002FAd type) on acoustic immittance testing\n* Without previous hearing aid intervention\n\nExclusion Criteria:\n\n* Premature and low birth weight infants: gestational age less than 37 weeks, or birth weight below 2500 grams\n* Participants diagnosed with enlarged vestibular aqueduct (EVA) by imaging (CT, MRI) or genetic testing\n* Participants with complicated medical problems or significant disabilities affecting growth and development (such as autism, recurrent epilepsy, severe heart disease requiring multiple surgeries, etc.) and considered unsuitable for this study by the investigators\n* Families who refused to participate in this study, or have already decided whether the participant will wear hearing aids or not (refused to randomization).\n* Participants who refused\u002Fwas unable to undergo study assessments as scheduled.","ALL","6 Months","4 Years",{"count":21,"type":22},236,"ESTIMATED","INTERVENTIONAL",[25],"NA","This is a multicenter, prospective, randomized controlled clinical trial to evaluate the effects of hearing aid intervention on brain and language development in children with bilateral mild sensorineural hearing loss. Eligible participants will be randomly assigned (1:1) to either the hearing aid intervention group or the control group. The primary outcome is the general developmental quotient of the Griffiths Development Scales-Chinese Edition (GDS-C) at 12 months. Secondary outcomes include auditory and speech development, language development, adaptive behavior, and brain structure and function assessed by MRI. Follow-up assessments will be conducted at baseline, 6 months, and 12 months.",[28],"Hearing Loss, Bilateral",[30,31,32,33],"Mild hearing loss","Hearing aids","Brain development","Children","NOT_YET_RECRUITING","2026-08-17",{"date":37,"type":38},"2026-08-19","ACTUAL",{"date":40,"type":22},"2026-08-31",{"date":42,"type":22},"2028-08-31",{"name":44,"class":45},"Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":54,"sex":17,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":23,"phases":59,"briefSummary":60,"conditions":61,"keywords":64,"overallStatus":75,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":46},"100651821","spatial-cues-task-demands-and-auditory-selective-attention-100651821","NCT07765186","Spatial Cues, Task Demands, and Auditory Selective Attention","How Spatial Cues Support Communication: Interactions Between Auditory Spatial Features and Task Demands Across Cortical Networks","Inclusion Criteria:\n\n* Adults with normal hearing, confirmed by audiometric assessment (thresholds within 20 dB HL of normal through 8 kHz), OR adults with bilateral cochlear implants who have used their implants for at least one year\n* Native speakers of American English\n* Normal or corrected-to-normal vision\n\nExclusion Criteria:\n\n* Known neurological disorders\n* For fMRI sessions (normal-hearing participants only): contraindications to MRI scanning; cochlear implant users do not complete MRI sessions",true,"18 Years","90 Years",{"count":58,"type":22},80,[25],"Understanding speech in restaurants and other noisy environments is the most common complaint from the more than 60 million Americans with hearing impairment. Succeeding in such environments requires a listener to first segregate sound sources and then selectively attend to the source of interest. This study examines how individual auditory spatial cues (interaural time differences and interaural level differences) support spatial selective attention, the cortical processes that underlie this ability, and how these processes are modulated by task demands. Participants with normal hearing and participants who use bilateral cochlear implants will perform listening tasks while brain and physiological responses are recorded (electroencephalography, functional near-infrared spectroscopy, pupillometry, and, for normal-hearing participants only, functional magnetic resonance imaging). The findings will provide new insights into the mechanisms of spatial selective attention and help guide clinical solutions for cochlear implant users, individuals with hearing impairment more generally, and older normal-hearing adults who have difficulty understanding speech in noisy environments.",[62,28,63],"Bilateral Cochlear Implants","Healthy",[65,66,67,68,69,70,71,72,73,74],"spatial hearing","auditory selective attention","interaural level difference","interaural time difference","cochlear implant","EEG","fNIRS","fMRI","pupillometry","speech in noise","RECRUITING","2026-08-10",{"date":78,"type":38},"2026-08-14",{"date":80,"type":38},"2025-10-22",{"date":82,"type":22},"2030-07",{"name":84,"class":45},"University of South Florida",{"id":86,"slug":87,"hasResults":11,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":4,"eligibilityCriteria":91,"healthyVolunteers":11,"sex":17,"minAge":92,"maxAge":93,"enrollmentInfo":94,"targetDuration":4,"studyType":23,"phases":96,"briefSummary":97,"conditions":98,"keywords":106,"overallStatus":75,"whyStopped":4,"lastUpdateSubmitDate":111,"lastUpdatePostDateStruct":112,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":46},"100520607","preschool-hearing-screening-100520607","NCT06058767","Preschool Hearing Screening","Pure-tone Audiometry Versus Otoacoustic Emissions for Preschool Hearing Screening","Inclusion Criteria:\n\n1. Age 2:0 - 6:0 years\n2. Enrolled in a community-based preschool program\n\nExclusion Criteria:\n\n1. Known permanent HL, by parental or school report\n2. Use of a hearing assistive device\n3. Parent does not consent for hearing screening\n4. Child was screened previously for this study\n5. Child is not present in preschool on day of hearing screening","2 Years","6 Years",{"count":95,"type":22},13764,[25],"Children who are deaf or hard-of-hearing (D\u002FHH) are at risk of speech and language delays, which can be mitigated through early identification and intervention. Identifying hearing loss (HL) during preschool is crucial, but the most effective hearing screening method for preschoolers remains uncertain. The purpose of this study is to learn whether, compared to the gold-standard two-stage Pure-tone audiometry (PTA) + otoacoustic emissions (OAE) screening (TS-PO), single-stage OAE (SS-O) screening alone is not inferior at identifying hearing loss when performed in a community-based preschool setting. This study holds the potential to improve early hearing loss detection and intervention among D\u002FHH children, reducing the likelihood of speech and language delays.\n\nA diverse group of 13,764 preschool-age children across community-based preschool centers will be recruited. The intervention involves all subjects undergoing both PTA and OAE screening, with the order determined through randomization. Children who show potential hearing issues based on screening results or teacher concerns will receive further testing to determine the final hearing outcome. Group allocation will be post-hoc, based on their screening results.\n\nIn addition to the primary objective, the study will compare other hearing screening measures and outcomes between the two methods (TS-PO and SS-O). This approach aims to reflect the real-life effectiveness of hearing screening in a diverse population. Ultimately, the study seeks to provide insights into an optimal hearing screening method that could prevent speech and language delays among D\u002FHH children.",[99,100,101,102,103,104,105,28],"Hearing Loss","Hearing Disorders in Children","Hearing Loss, Sensorineural","Hearing Loss, Conductive","Hearing Loss, Unilateral","Hearing Loss, Noise-Induced","Hearing Loss, Mixed",[99,89,107,108,109,110],"Otoacoustic Emissions","Pure-Tone Testing","Childhood Hearing Screening","Childhood Hearing Loss","2026-01-29",{"date":113,"type":38},"2026-02-02",{"date":115,"type":38},"2023-10-01",{"date":117,"type":22},"2028-02-01",{"name":119,"class":45},"University of California, San Francisco",{"id":121,"slug":122,"hasResults":11,"nctId":123,"briefTitle":124,"officialTitle":125,"acronym":4,"eligibilityCriteria":126,"healthyVolunteers":11,"sex":17,"minAge":127,"maxAge":128,"enrollmentInfo":129,"targetDuration":4,"studyType":23,"phases":131,"briefSummary":132,"conditions":133,"keywords":4,"overallStatus":75,"whyStopped":4,"lastUpdateSubmitDate":134,"lastUpdatePostDateStruct":135,"startDateStruct":136,"completionDateStruct":138,"leadSponsor":140,"locationsCount":46},"100582185","sentence-shaping---dhh-100582185","NCT06860022","Sentence Shaping - DHH","Sentence Shaping: Written Language Intervention for Deaf and Hard of Hearing Middle Schoolers","Inclusion Criteria:\n\n* Children in grades five through eight\n* deaf or hard of hearing\n* use spoken English and American Sign Language (ASL)\n* bilateral hearing loss\n* the ability to read and understand the grammatical structures of interest\n* already be writing sentences, but demonstrate errors in word order and\u002For grammar.\n\nExclusion Criteria:\n\n* diagnosis of dyslexia\n* uncorrected vision impairment (i.e., identified vision loss without use of corrective lenses that interferes with eligibility evaluation tasks)\n* evidence of severe motor impairment (i.e., insufficient motor skills to complete eligibility evaluation tasks independently).","9 Years","15 Years",{"count":130,"type":22},30,[25],"The proposed research addresses a long-standing and important challenge of improving literacy skills of children who are deaf and hard of hearing, a historically under researched group. The investigators aim to leverage shape coding - an empirically validated intervention approach for constructing sentences in spoken English - for improving how efficiently children who are deaf and hard of hearing learn to correctly construct sentences in written English. To advance the promising yet underutilized research on shape coding, the investigators complete the next logical step of applying the visual supports provided with shape coding to written language for deaf and hard of hearing children. Shape coding has been effective for teaching sentence structure in spoken English to children with language disabilities and has recently been applied to sentence structure in American Sign Language with deaf and hard of hearing children. Intervention involving shape coding is predicted to result in increased accuracy of word order in sentences in written English because deaf and hard of hearing children often benefit from visual information. The investigators will accomplish this aim using single case multiple probe across participants design studies with 30 fifth through eighth grade children who are deaf and hard of hearing. The knowledge gained will guide language and literacy intervention for children who are deaf and hard of hearing.",[28],"2025-10-20",{"date":80,"type":38},{"date":137,"type":38},"2025-08-28",{"date":139,"type":22},"2026-10",{"name":141,"class":45},"Vanderbilt University",{"id":143,"slug":144,"hasResults":11,"nctId":145,"briefTitle":146,"officialTitle":146,"acronym":4,"eligibilityCriteria":147,"healthyVolunteers":11,"sex":17,"minAge":55,"maxAge":148,"enrollmentInfo":149,"targetDuration":4,"studyType":23,"phases":151,"briefSummary":152,"conditions":153,"keywords":4,"overallStatus":75,"whyStopped":4,"lastUpdateSubmitDate":154,"lastUpdatePostDateStruct":155,"startDateStruct":157,"completionDateStruct":159,"leadSponsor":161,"locationsCount":163},"100416838","clinical-utility-of-residual-hearing-in-the-cochlear-implant-ear-100416838","NCT04707885","Clinical Utility of Residual Hearing in the Cochlear Implant Ear","Inclusion Criteria:\n\n1. Provision of signed and dated informed consent form.\n2. Adults, males and females, ages 18 -79 who have a bilateral sensorineural hearing loss with postlingual onset.\n3. Minimum of 30 days experience with appropriately fit binaural amplification (standardized National Acoustic Laboratories (NAL) fitting method) verified with real ear measurements within 5 dB SPL of targets.\n4. Limited benefit from conventional amplification in the best aided condition as defined by test scores of:\n\n   1. The ear to implanted: Consonant-nucleus-consonant (CNC) words ≤ 60% or AzBio sentences (+10, +5 dB SNR ≤ 60% correct)\n   2. Contralateral ear: ≤ 80% on CNC words or AzBio sentences (+10, +5 dB SNR ≤ 80% correct)\n5. Low frequency Pure Tone Average (PTA- 125, 250, 500 Hz) ≤ 55 dB HL in the ear to be implanted.\n6. Severe to profound mid to high-frequency sensorineural hearing loss (threshold average of 1000, 2000, 3000, and 4000 Hz ≥75 dB HL) in the ear to be implanted.\n7. Low frequency PTA ≤ 55 dB HL sloping to moderately severe to profound mid-to high frequency sensorineural hearing loss (threshold average of 1000, 2000, 3000, 4000 Hz ≥ 60 dB) in the contralateral ear.\n8. Proficient in English.\n9. Undergoing implantation with a current generation CI device from either Cochlear Limited or Advanced Bionics AG.\n\n   1. Cochlear Limited devices include: Nucleus CI612, CI622, CI632, CI624\n   2. Advanced Bionics AG devices include: HiFocus SlimJ, Mid-Scala\n10. Stated willingness and ability to complete testing and all associated study visits.\n\nExclusion Criteria:\n\n1. Previous cochlear implantation.\n2. Prelingual onset of hearing loss.\n3. Abnormal inner ear anatomy on CT imaging.\n4. Auditory neuropathy spectrum disorder.\n5. Retrocochlear pathology such as a vestibular schwannoma or stroke.\n6. Unwillingness or inability to comply with all investigational requirements including the randomization process.\n7. Additional medical, or social barriers that would prevent completion of all study requirements.\n8. Medical condition contraindicated for surgery.\n9. Device selection of Med El CI (per the patient's selection).","79 Years",{"count":150,"type":22},40,[25],"The current study is a randomized multi-center clinical trial that investigates the role an intraoperative hearing monitoring system (electrocochleography) has on helping to save residual hearing in patients undergoing cochlear implantation (CI).",[101,99,28],"2025-09-05",{"date":156,"type":38},"2025-09-12",{"date":158,"type":38},"2021-11-10",{"date":160,"type":22},"2027-12-31",{"name":162,"class":45},"Ohio State University",5,{"id":165,"slug":166,"hasResults":11,"nctId":167,"briefTitle":168,"officialTitle":169,"acronym":4,"eligibilityCriteria":170,"healthyVolunteers":11,"sex":17,"minAge":55,"maxAge":171,"enrollmentInfo":172,"targetDuration":4,"studyType":23,"phases":173,"briefSummary":174,"conditions":175,"keywords":4,"overallStatus":75,"whyStopped":4,"lastUpdateSubmitDate":176,"lastUpdatePostDateStruct":177,"startDateStruct":179,"completionDateStruct":181,"leadSponsor":183,"locationsCount":46},"100601871","speech-understanding-and-listening-effort-benefits-of-hearing-instruments-100601871","NCT07116135","Speech Understanding and Listening Effort Benefits of Hearing Instruments","Speech Understanding and Listening Effort Benefits of Infinio Sphere","Inclusion Criteria:\n\n* Adult 18-95 years\n* N3 or N4 hearing loss\n* Experienced hearing aid user\n* English fluency\n* Cognitively able to complete complex listening tasks\n\nExclusion Criteria:\n\n* Outside of specified age range\n* Vulnerable populations\n* Hearing within normal limits or otherwise not appropriate for hearing instruments under study\n* Inability to read, write, or speak English\n* Inability to complete complex listening tasks","95 Years",{"count":130,"type":22},[25],"The goal of this clinical study is to investigate the benefits of hearing instrument use in adults with hearing loss. The main questions it aims to answer are:\n\nDoes hearing instrument use improve speech understanding and listening effort amount people with hearing loss? Researchers will compare varying models of hearing instruments to see how speech understanding and listening effort are impacted.\n\nParticipants will be asked to wearing varying hearing instruments and participate in lab-based activities to evaluate their speech understanding, listening effort, and subjective preference.",[28],"2025-08-04",{"date":178,"type":38},"2025-08-11",{"date":180,"type":38},"2025-02-05",{"date":182,"type":22},"2025-12",{"name":184,"class":185},"Sonova AG","INDUSTRY"]