[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"heart-failure-new-york-heart-association-class-iv\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:heart-failure-new-york-heart-association-class-iv":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":5},"100659355","inspiratory-muscle-training-in-hospitalized-patients-with-heart-failure-awaiting-advanced-therapies-a-single-center-pilot-feasibility-study-100659355",false,"NCT07862738","Inspiratory Muscle Training in Hospitalized Patients With Heart Failure Awaiting Advanced Therapies: a Single-center Pilot Feasibility Study","Comparing the Addition of Inspiratory Muscle Training (IMT) to Usual Care Physical Therapy in Hospitalized Patients With Heart Failure Awaiting Advanced Therapies: a Single-center Pilot Feasibility Study","Inclusion Criteria:\n\n1. 18 years old or older\n2. Able to provide consent and willing to participate in study procedures\n3. Currently hospitalized awaiting advanced therapies (LVAD or heart transplant)\n4. Diagnosed with NYHA class III or IV heart failure\n5. Able to follow instructions including the use of the Borg Dyspnea scale\n6. Physically able to independently hold and use the IMT\n7. Patients will undergo screening with or without active PT orders. To be enrolled in the study, patient must have an active physical therapy order. . If no active order exists, one will be requested from medical team following the screening and prior to enrollment.\n8. Participants must meet institutional criteria for participation in physical therapy and mobility activities prior to enrollment and before each IMT session. Medical stability may include:\n\n   * Mean arterial pressure (MAP) ≥ 60 mmHg and ≤ 120 mmHg\n   * Resting heart rate between 40 and 140 beats per minute\n   * No evidence of active myocardial ischemia or unstable angina\n   * No uncontrolled atrial or ventricular arrhythmias\n   * No escalating vasopressor or inotropic support at time of intervention\n   * Oxygen saturation ≥ 94% on current oxygen support\n   * Respiratory rate between 8 and 35 breaths per minute\n   * Ability to follow simple commands and participate in study procedures\n   * No acute neurologic, respiratory, or hemodynamic deterioration requiring immediate escalation of care\n   * Clearance by the treating medical team to participate in rehabilitation activities\n\nExclusion Criteria:\n\n1. Patients discharged from the hospital to await advanced therapies (LVAD or heart transplant)\n2. Patients with an expectedpreoperative inpatient hospital stay of less than 10 days, based onreview of clinical status, treatment plan, and timing of expected surgery\n3. Patients with acute pneumothorax\n4. Presence of acute rib fracture(s)\n5. Patients with acute cerebrovascular accident\n6. Untreated hypertension, defined as systolic blood pressure consistently \\>140 mmHg or diastolic blood pressure consistently \\>90 mmHg in the absence of antihypertensive therapy.\n7. Acute delirium\n8. Perforated tympanic membrane\n9. Hemodynamic instability\n10. Abdominal surgery during present admission\n11. Patients with planned multiple organ transplant (e.g. heart and kidney, heart and lung)\n12. Patients currently requiring mechanical ventilatory support\n13. A burst eardrum that has not fully healed, or any other condition of the eardrum\n14. Patients with asthma who suffer from frequent severe exacerbations\n15. Patients with marked elevated left ventricular end-diastolic volume and pressure\n16. Patients with worsening heart failure signs and symptoms after IMT\n17. If you have suffered from or are likely to suffer from costochondritis","ALL","18 Years",{"count":19,"type":20},30,"ESTIMATED","INTERVENTIONAL",[23],"NA","The primary objective of this study is to evaluate the feasibility and safety of inspiratory muscle training (IMT) when implemented as part of routine inpatient physical therapy care in patients undergoing evaluation for advanced heart therapies. The secondary aim is to determine if IMT improves 6-minute walk test (6MWT), dyspnea, Maximal Inspiratory Pressure (MIP) pre-operatively. Thirdly, to determine if IMT decreases ICU and hospital length of stay post-operatively.",[26,27,28],"Heart Failure","Heart Failure New York Heart Association Class III","Heart Failure New York Heart Association Class IV","NOT_YET_RECRUITING","2026-10-02",{"date":32,"type":33},"2026-10-07","ACTUAL",{"date":35,"type":20},"2026-11-10",{"date":37,"type":20},"2027-11-10",{"name":39,"class":40},"NYU Langone Health","OTHER"]