[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hemodynamic-response-to-laryngoscopy-and-tracheal-intubation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hemodynamic-response-to-laryngoscopy-and-tracheal-intubation":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":4},"100654053","intravenous-magnesium-sulphate-versus-lignocaine-for-attenuating-hemodynamic-responses-to-laryngoscopy-and-endotracheal-intubation-100654053",false,"NCT07793955","Intravenous Magnesium Sulphate Versus Lignocaine for Attenuating Hemodynamic Responses to Laryngoscopy and Endotracheal Intubation","Comparison of Intravenous Magnesium Sulphate and Lignocaine in Attenuation of Hemodynamic Responses to Laryngoscopy and Endotracheal Intubation","Inclusion Criteria:\n\n* age 18-70 yrs\n* male and female patients\n* patients undergoing elective or emergency procedures under general anesthesia\n\nExclusion Criteria:\n\n* pregnancy\n* anticipated difficult airway",true,"ALL","18 Years","70 Years",{"count":21,"type":22},78,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study will compare intravenous magnesium sulfate with intravenous lidocaine for reducing the cardiovascular response to endotracheal intubation in adult patients undergoing general anesthesia. Eligible participants will receive either magnesium sulfate or lidocaine before endotracheal intubation. Heart rate and blood pressure will be recorded at predefined time points before and after intubation to compare the effectiveness of the two interventions in attenuating the hemodynamic response to laryngoscopy and endotracheal intubation.",[28],"Hemodynamic Response to Laryngoscopy and Tracheal Intubation",[30,31,32,33,34],"magnesium suplhate","lignocaine","endotracheal intubation","hemodynamic response","laryngoscopy","NOT_YET_RECRUITING","2026-09-02",{"date":38,"type":39},"2026-09-08","ACTUAL",{"date":41,"type":22},"2026-08-20",{"date":43,"type":22},"2026-09-20",{"name":45,"class":46},"Lady Reading Hospital, Pakistan","OTHER_GOV",{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":23,"phases":57,"briefSummary":58,"conditions":59,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":4},"100653108","hemodynamic-responses-to-laryngoscopy-and-tracheal-intubation-100653108","NCT07783256","Hemodynamic Responses to Laryngoscopy and Tracheal Intubation","Effectiveness of Intravenous Ketodex Versus Ketofol for Obtunding Hemodynamic Responses to Laryngoscopy and Tracheal Intubation in Adult Elective Middle Ear Surgery Patients: A Prospective Randomized Comparative Study","Inclusion Criteria:\n\n* Adult patients scheduled for elective middle ear surgery under general anesthesia, ASA status I-II, aged from 18 to 60 years old of either sex.\n\nExclusion Criteria:\n\n* Full stomach or emergency surgery\n* Any known contraindications or allergy to ketamine, dexmedetomidine, or propofol\n* Pregnancy or breastfeeding women\n* Body mass index (BMI) \\> 35 Kg\u002Fm2\n* History of hepatic, renal, or cardiac disease\n* Patients in whom the duration of laryngoscopy will last more than 25 seconds\n* Chronic opioid use, or history of neuropsychiatric disorders\n* Patient refusal","60 Years",{"count":56,"type":22},70,[25],"Laryngoscopy and tracheal intubation lead to tachycardia and hypertension due to increase in the plasma catecholamines subsequent to sympathetic stimulation.",[28],{"date":61,"type":39},"2026-08-24",{"date":63,"type":22},"2026-12-20",{"date":65,"type":22},"2028-12-20",{"name":67,"class":68},"Assiut University","OTHER"]