[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hemostasis-of-arterial-punctures\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hemostasis-of-arterial-punctures":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,41],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":4,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100646996","flow-dynamics-during-simulated-hemostasis-at-the-proximal-and-distal-radial-arteries-100646996",false,"NCT07686003","Flow Dynamics During Simulated Hemostasis at the Proximal and Distal Radial Arteries","Flow Dynamics During Simulated Hemostasis at the Proximal and Distal Radial Arteries: The FLOW-PRADA Study","FLOW-PRADA","Inclusion Criteria:\n\nA. Adults aged ≥19 years B. Patients scheduled for coronary angiography due to atypical chest pain, stable angina, or acute coronary syndrome C. Patients undergoing transthoracic echocardiography for assessment of cardiac function prior to coronary angiography D. Palpable proximal and distal radial arteries\n\nExclusion Criteria:\n\nA. Cardiogenic shock B. Patients who have undergone coronary angiography via distal radial access prior to echocardiographic evaluation C. Refusal or inability to provide informed consent D. Presence of an ipsilateral arteriovenous fistula E. Pregnant or breastfeeding women",true,"ALL",{"count":20,"type":21},220,"ESTIMATED","OBSERVATIONAL","Transradial access (TRA) has been widely adopted for coronary angiography and percutaneous coronary intervention, as it has been shown to significantly reduce bleeding complications, vascular complications, and mortality compared with transfemoral access (TFA). Based on this evidence, recent international guidelines recommend TRA as the preferred access strategy.\n\nRadial artery occlusion (RAO), a potential complication following TRA, is often clinically silent and therefore underestimated. However, RAO has important clinical implications, particularly in patients who may require repeated coronary procedures, those in whom the radial artery may be used as a conduit for coronary artery bypass grafting, or patients with chronic kidney disease requiring arteriovenous fistula formation. Therefore, maintaining radial artery patency after the procedure is of considerable clinical importance.\n\nDistal radial access (DRA), which utilizes the radial artery at the anatomical snuffbox, is a relatively recent approach. Multiple studies and meta-analyses have demonstrated that DRA provides comparable procedural success rates to TRA while significantly reducing bleeding complications and the incidence of RAO. Notably, despite the generally accepted association between smaller vessel diameter and higher risk of occlusion, DRA paradoxically shows a lower incidence of RAO. The underlying mechanism for this observation remains incompletely understood.\n\nSgueglia et al. evaluated peak systolic velocity using Doppler ultrasonography under conditions of arterial compression and reported that antegrade blood flow was better preserved during distal radial artery compression compared with proximal radial artery compression. This finding suggests a potential mechanistic explanation for the lower incidence of RAO observed with DRA.\n\nHowever, there is a paucity of studies that systematically evaluate hemodynamic changes under simulated real-world hemostatic conditions at both proximal and distal radial arteries.\n\nTherefore, the aim of this study is to quantitatively assess hemodynamic changes induced by simulated occlusive hemostasis at the proximal and distal radial arteries using Doppler ultrasonography, and to elucidate the mechanisms underlying the lower incidence of RAO observed with DRA.",[25],"Hemostasis of Arterial Punctures",[27,28],"Distal radial access","Hemostasis","NOT_YET_RECRUITING","2026-07-01",{"date":32,"type":33},"2026-07-06","ACTUAL",{"date":30,"type":21},{"date":36,"type":21},"2026-12-31",{"name":38,"class":39},"Wonju Severance Christian Hospital","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":18,"minAge":48,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":51,"phases":52,"briefSummary":54,"conditions":55,"keywords":56,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":4},"100592252","clinical-use-study-of-saph-device-for-patent-hemostasis-after-a-transradial-procedure-100592252","NCT06991010","Clinical Use Study of SAPH Device for Patent Hemostasis After a Transradial Procedure","One-arm, Prospective, Clinical Use Study of the Suction-Activated Patent Hemostasis (SAPH) Device After a Transradial Procedure","Inclusion Criteria:\n\n1. Patient is 21 years or older.\n2. Patient is scheduled to undergo a coronary or peripheral catheterization procedure requiring 5 or 6 Fr transradial sheath access (TRA) with planned same-day discharge\n3. Patient has a Reverse Barbeau test result of Type A, B or C (patent radial artery)\n4. Patient is able to understand informed consent language\n5. Patient is willing and able to sign informed consent and adhere to the protocol requirements\n\nExclusion Criteria:\n\n1. Patient had a prior ipsilateral TRA procedure\n2. Patient has scleroderma, vasculitis, or Raynaud's syndrome (primary or secondary)\n3. Patient has cellulitis overlying radial artery\n4. Patient requires uninterrupted oral systemic anticoagulation\n5. Patient has intolerance to standard anticoagulants used in TRA procedures\n6. Patient has non-palpable radial pulse or Reverse Barbeau test Type D response\n7. Patient is participating in another investigational study\n8. Patient is a prisoner\n9. Patient, in the principal investigator's opinion, would not be able to comply with protocol requirements including self-report of comfort and 30-day follow up\n10. Patient is receiving glycoprotein IIb\u002FIIIa inhibitors\n11. Patients with allergy to medical adhesives","21 Years",{"count":50,"type":21},50,"INTERVENTIONAL",[53],"NA","This is a prospective, multicenter study intended to provide supportive clinical information on the use of the SAPH device to achieve radial artery patent hemostasis after a transradial procedure.",[25],[57,58,59,60],"Artery clamp","Transradial access","Radial artery patency","Radial artery hemostasis","2025-07-10",{"date":63,"type":33},"2025-07-15",{"date":65,"type":21},"2025-08-01",{"date":67,"type":21},"2025-11-28",{"name":69,"class":70},"Transradial Technologies, LLC","INDUSTRY"]