[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hiatal-hernia-large\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hiatal-hernia-large":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":5},"100648235","laparoscopic-nissen-versus-toupet-fundoplication-for-hiatal-hernia-100648235",false,"NCT07718828","Laparoscopic Nissen Versus Toupet Fundoplication for Hiatal Hernia.","Laparoscopic Nissen Versus Toupet Fundoplication for Gastroesophageal Reflux Management in Patients With Hiatal Hernia: A Patient- and Assessor-Blinded Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients aged 18 to 90 years\n* Patients diagnosed with primary hiatal hernia by fibrogastroscopy and\u002For barium swallow examination\n* Patients with symptoms of gastroesophageal reflux disease\n* Patients scheduled for elective laparoscopic hiatal hernia repair with fundoplication\n* Patients able to provide informed consent\n\nExclusion Criteria:\n\nPatients younger than 18 years or older than 90 years Patients with recurrent hiatal hernia Patients who are not suitable for general anesthesia Patients who prefer a surgical approach other than laparoscopic surgery Patients who are unable or unwilling to provide informed consent","ALL","18 Years","90 Years",{"count":20,"type":21},200,"ESTIMATED","INTERVENTIONAL",[24],"NA","This randomized controlled trial compares laparoscopic Nissen fundoplication and laparoscopic Toupet fundoplication in patients undergoing surgical treatment for hiatal hernia associated with gastroesophageal reflux disease. Participants will be randomly assigned to one of two surgical groups. The study will evaluate postoperative pain, health-related quality of life, hospital stay, recurrence of reflux symptoms, gas-bloat symptoms, operative time, fundoplication time, and postoperative complications.",[27,28,29],"Hiatal Hernia, Paraesophageal","Hiatal Hernia Large","Hiatal Hernia With Gastroesophageal Reflux Disease",[31,32,33,34,35],"Hiatal hernia","Gastroesophageal reflux disease","Laparoscopic fundoplication","Toupet fundoplication","Antireflux surgery","RECRUITING","2026-07-17",{"date":39,"type":40},"2026-07-22","ACTUAL",{"date":42,"type":40},"2023-05-29",{"date":44,"type":21},"2027-01-31",{"name":46,"class":47},"Sofia Med Hospital","OTHER"]