[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"high-flow-oxygen-therapy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:high-flow-oxygen-therapy":24},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,46,80],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100651412","high-flow-nasal-oxygyen-therapy-during-sedated-endobronchial-ultrasound-guided-transbronchial-needle-aspirationebus-tbna-100651412",false,"NCT07760727","High-Flow Nasal Oxygyen Therapy During Sedated Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration(EBUS-TBNA)","The Effects of High-Flow Nasal Oxygen Therapy on Respiratory Complications and Post-Procedural Recovery Time in Patients Undergoing Sedated EBUS-TBNA","Inclusion Criteria:\n\nAge ≥18 years. Scheduled to undergo sedated EBUS-TBNA. Ability to provide written informed consent. ASA physical status I-III.\n\nExclusion Criteria:\n\n* Age \\\u003C18 years.\n* Pregnancy.\n* Requirement for endotracheal intubation or general anesthesia.\n* Severe hemodynamic instability.\n* Refusal to participate in the study.\n* Contraindication to high-flow nasal oxygen therapy.","ALL","18 Years",{"count":19,"type":20},120,"ESTIMATED","OBSERVATIONAL","This study aims to evaluate the effects of high-flow nasal oxygen therapy on respiratory complications, blood gas parameters, and post-procedural recovery in patients undergoing sedated endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). Participants will be assigned to receive either high-flow nasal oxygen therapy or conventional oxygen therapy during the procedure. The incidence of respiratory complications, blood gas changes, and recovery outcomes will be compared between the two groups.",[24,25,26,27,28],"High Flow Oxygen Therapy","ENDOBRONCHIAL ULTRASOUND - TRANSBRONCHIAL NEEDLE ASPIRATION","Sedation","Sedation Complication","Blood Gas Analysis",[30,31,26,32,28],"High flow oxygen therapy,","Endobronchial Ultrasound-Transbronchial Needle Aspiration(EBUS-TBNA)","Sedation Complications","NOT_YET_RECRUITING","2026-08-07",{"date":36,"type":37},"2026-08-12","ACTUAL",{"date":39,"type":20},"2026-08-20",{"date":41,"type":20},"2026-11-20",{"name":43,"class":44},"Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":56,"phases":57,"briefSummary":59,"conditions":60,"keywords":63,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":45},"100635969","high-flow-tracheal-oxygen-for-weaning-of-tracheostomized-patients-100635969","NCT07559591","High Flow Tracheal Oxygen for Weaning of Tracheostomized Patients","High Flow Tracheal Oxygen for Weaning of Tracheostomized Mechanically Ventilated Patients: A Pilot Randomised Controlled Trial (HFTO WEAN Trial)","HFTO-WEAN","Inclusion Criteria:\n\n1. Adults ≥ 18 years of age\n2. Intensive care unit (ICU) patients with tracheostomy inserted during the index ICU admission.\n3. Mechanically ventilated for ≤60 days.\n4. Successful spontaneous breathing trial for 1 hour.\n\nExclusion Criteria:\n\n1. Planned tracheostomy post head and neck surgery with ICU stay less than 48 hours\n2. Patient transferred from another hospital only if the intubation and tracheostomy dates are unavailable, otherwise would be eligible.\n3. Patient with an imminent plan for palliation and comfort care.\n4. Patient or substitute decision-maker declines consent to the study.\n5. The treating physician declines consent to the study.",{"count":55,"type":20},88,"INTERVENTIONAL",[58],"NA","In this pilot randomized controlled trial (RCT), the investigators aim to explore the feasibility of conducting a powered RCT that examines the efficacy and safety of high flow tracheal oxygen (HFTO) in weaning critically ill tracheostomy patients from mechanical ventilation.\n\nObjective of the study\n\n1. To assess the feasibility of conducting a larger RCT as primary objective.\n2. To explore the effect of using HFTO in mechanically ventilated tracheostomized critically ill patients on ventilator-free days (VFD) compared to standard of care method using tracheal mask (TM) as secondary objective.",[61,62,24],"Tracheostomized Patients","Mechanical Ventilation Weaning",[64,65,66,67,68,69],"tracheostomized patients","tracheostomy","mechanical ventilation weaning","high flow tracheal oxygen","mechanical ventilation liberation","critically ill","RECRUITING","2026-05-29",{"date":73,"type":37},"2026-06-02",{"date":75,"type":37},"2026-05-17",{"date":77,"type":20},"2027-05",{"name":79,"class":44},"King Faisal Specialist Hospital & Research Center",{"id":81,"slug":82,"hasResults":11,"nctId":83,"briefTitle":84,"officialTitle":84,"acronym":4,"eligibilityCriteria":85,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":86,"targetDuration":4,"studyType":56,"phases":88,"briefSummary":89,"conditions":90,"keywords":4,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":45},"100605875","comparison-of-two-spo2-targets-with-two-different-oximeters---impact-on-fio2-during-nasal-high-flow-oxygen-therapy-100605875","NCT07168213","Comparison of Two SpO2 Targets With Two Different Oximeters - Impact on FiO2 During Nasal High Flow Oxygen Therapy","Inclusion Criteria:\n\n* ≥ 18 years of age\n* Admiitted in intensive care unit\n* Presence of an arterial catheter\n* Ongoing on high flow nasal oxygen therapy with SpO2 between 88 and 100% with a FiO2 between 40 and 80% with the usual oximeter .\n\nExclusion Criteria:\n\n* No SpO2 signal with oximeter in use\n* False nails or nail polish\n* Methemoglobinemia \\>0.015 on last available arterial gas\n* Patient in isolation (multi-resistant bacteria, C-Difficile, SARS-CoV-2 ...)\n* Expected to use another respiratory support within two hour of inclusion (NIV or mechanical ventilation)",{"count":87,"type":20},30,[58],"Several factors can influence oxygenation monitoring and respiratory support through oxygen therapy: the type of oximeter used, skin pigmentation, and the oxygenation target. It is essential to have an accurate measurement of SpO2 in order to optimize the flow of oxygen or FiO2 administered to patients. The question arises as to the impact of these confounding factors on the FiO2 set during high-flow nasal oxygen therapy. The aim of the study is to evaluate the impact of the oxygenation target and the oximeter used on FiO2 in patients receiving high-flow nasal oxygen therapy.",[91,92,24,93],"Oxygen Delivery","Acute Respiratory Failure","Hypoxemic Acute Respiratory Failure","2026-03-05",{"date":96,"type":37},"2026-03-09",{"date":98,"type":37},"2025-10-21",{"date":100,"type":20},"2027-12",{"name":102,"class":44},"Laval University"]