[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hope\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hope":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,83],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100644955","bereaved-parent-conversations-on-hope-100644955",false,"NCT07675083","Bereaved Parent Conversations on Hope","Bereaved Parent Conversations on Hope (BeHope)","Inclusion Criteria\n\nIntervention Participants must be:\n\n* Students, observers, trainees, and newly hired clinicians,\n* ≥18 years old,\n* participating in or observing clinical care at St. Jude Children's Research Hospital, and\n* willing to participate in the virtual intervention and associated study activities as learners\n\nIntervention Facilitators must be:\n\n* Bereaved parents,\n* ≥ 18 years old,\n* screened and cleared to volunteer as advisers with St. Jude Children's Research Hospital through Family, Guest and Volunteer Services, and\n* willing to participate in the virtual intervention and associated study activities as a facilitator\n\nExclusion Criteria\n\nIntervention Participants:\n\n* Age \\\u003C 18 years, decline participation, or unable to speak\u002Fwrite in conversational English.\n\nIntervention Facilitators:\n\n* Age \\\u003C 18 years, decline participation, or unable to speak\u002Fwrite in conversational English.",true,"ALL","18 Years",{"count":20,"type":21},75,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study looks at whether it is possible and helpful to have video call conversations about how hopes can change through the cancer journey between bereaved parents and learners at a children's cancer center.",[27],"Hope",[29,30,31,32,33],"Cancer Journey","St. Jude Children's Research Hospital (SJCRH)","SJCRH Bereaved Parent Advisors","SJCRH Learners","Virtual Intervention","RECRUITING","2026-07-27",{"date":37,"type":38},"2026-07-29","ACTUAL",{"date":40,"type":38},"2026-07-24",{"date":42,"type":21},"2028-10",{"name":44,"class":45},"St. Jude Children's Research Hospital","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":56,"conditions":57,"keywords":67,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":82},"100647853","effects-of-a-perma-h-model-mobile-based-rehabilitation-support-program-on-hope-self-efficacy-perceived-social-support-and-rehabilitation-outcomes-in-post--tracheostomy-oral-cancer-patients-100647853","NCT07714967","Effects of a Perma-h Model Mobile-based Rehabilitation Support Program on Hope, Self-efficacy, Perceived Social Support and Rehabilitation Outcomes in Post- Tracheostomy Oral Cancer Patients","Inclusion Criteria:\n\n* Aged ≥18 years\n* Pathologically diagnosed with oral squamous cell carcinoma and undergoing, or scheduled to undergo, tracheostomy followed by decannulation\n* Fully conscious, with a Glasgow Coma Scale score of 15, and able to successfully complete the Three-Step Command Test, indicating intact comprehension ability\n* Able to communicate effectively through verbal speech or alternative methods, including writing, gestures, electronic device input, or voice-assisted tools\n* Able to use WeChat independently or after brief guidance, without communication barriers\n* Has at least one regular family caregiver; both the patient and caregiver fully understand the study content and voluntarily provide written informed consent\n* Free from severe cardiovascular, cerebrovascular, hepatic, renal, or pulmonary disease\n\nExclusion Criteria:\n\n* Presence of other serious malignancies or extensive tumor metastasis\n* Previous or current diagnosis of severe mental illness, such as schizophrenia or severe bipolar disorder\n* Significant cognitive impairment, severe depressive symptoms, or suicide risk that precludes effective participation in psychological interventions\n* Inability to complete assessments or interventions due to severe hearing, visual, or language impairments\n* Inability to communicate effectively through any available alternative means\n* Lack of access to a smartphone and absence of a designated caregiver\n* Explicit unwillingness or inability to use a mobile-based rehabilitation support program\n* Unexpected inability to complete the full intervention cycle, including planned hospital transfer or prolonged loss to follow-up\n* Concurrent participation in other clinical studies primarily focused on psychological or mobile health interventions that could confound study outcomes",{"count":54,"type":21},100,[24],"The goal of this study (exploratory sequential design; mixed-methods study) is to evaluate whether a PERMA-H model mobile-based rehabilitation support program delivered to post-tracheostomy oral cancer patients can improve psychological and rehabilitation outcomes, compared with a control group receiving usual care\u002Fstandard support. The study will focus on post-tracheostomy oral squamous cell carcinoma (OSCC) patients (aged ≥18 years) who are undergoing or scheduled to undergo tracheostomy followed by decannulation, and who have adequate communication ability and caregiver support.\n\nThe main questions it aims to answer are:\n\nDoes the PERMA-H model mobile-based rehabilitation support program improve patients' hope? (primary hypothesis\u002Foutcome measure 1) Does the PERMA-H model mobile-based rehabilitation support program improve patients' self-efficacy, perceived social support, and rehabilitation outcomes? (primary hypothesis\u002Foutcome measure 2) If there is a comparison group, researchers will compare the PERMA-H model mobile-based rehabilitation support program (intervention group) to a control group receiving standard\u002Fusual care (control group) to determine differences in outcomes between groups.\n\nParticipants will be asked to complete the main study tasks, including:\n\nparticipating in qualitative interviews to explore their digital needs, expectations, and experiences regarding psychosocial care (Phase I); using the WeChat mini-program platform that incorporates a PERMA-H evidence-based module set and a chatbot (Decannulationbot \u002F Digital rehabilitation Assistant, DDA) as part of the rehabilitation support program; completing validated assessments at study endpoints to measure hope (Herth Hope Index), self-efficacy (General Self-Efficacy Scale), and perceived social support (Perceived Social Support Scale), as well as rehabilitation-related outcomes (including rehabilitation willingness\u002Fparticipation and functional measures such as swallowing function and speech intelligibility as rated by speech-language pathologists).\n\nExpected outcomes include: comprehensive qualitative findings to inform the content and delivery of digital psychosocial support; a functional mobile intervention platform with evidence-based modules validated through expert appraisal and pilot testing; and statistically significant improvements in hope, self-efficacy, perceived social support, and rehabilitation outcomes in the intervention group compared with the control group.",[58,59,60,61,62,27,63,64,65,66],"Tracheostomized Patients","Decanulation","Oral Cancer , Oral Squamous Cell Carcinoma, Oral Cavity Cancer","Rehabilitation Outcome","Mental Health","Self Efficacy","Perceived Social Support","Swallowing Function","Speech Intelligibility",[68,69,70,71],"PERMA-H","chatbot","Digital Rehabilitation Support","MODEL MOBILE","NOT_YET_RECRUITING","2026-07-15",{"date":75,"type":38},"2026-07-20",{"date":77,"type":21},"2026-08-01",{"date":79,"type":21},"2027-02-01",{"name":81,"class":45},"Hainan Medical College",2,{"id":84,"slug":85,"hasResults":11,"nctId":86,"briefTitle":87,"officialTitle":87,"acronym":4,"eligibilityCriteria":88,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":89,"targetDuration":4,"studyType":22,"phases":91,"briefSummary":92,"conditions":93,"keywords":4,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":4},"100551883","the-effect-of-book-reading-on-comfort-hope-anxiety-and-vital-signs-of-intensive-care-unit-patients-100551883","NCT06465875","The Effect of Book Reading on Comfort, Hope, Anxiety and Vital Signs of Intensive Care Unit Patients","Inclusion Criteria:\n\n1. Over 18 years of age,\n2. Stable clinical condition after intensive care unit admission,\n3. Have no physical or mental impairment in answering the questions,\n4. No verbal communication disability (hearing and speech),\n5. No diagnosed psychiatric disorder,\n6. With a Glasgow Coma Scale score of 15,\n7. Not receiving sedation for at least 12 hours,\n8. Will be hospitalized for at least 3 days from the time of enrollment in the study,\n9. Individuals who agree to participate in the study will be included in the study.\n\nExclusion Criteria:\n\n1. People with hearing or vision problems,\n2. Intubated,\n3. Any diagnosed neurological or psychological disorder,\n4. Transferred to another unit or exitus before the specified period,\n5. Individuals who do not agree to participate in the study will not be included in the study.",{"count":90,"type":21},70,[24],"This study was planned to investigate the effect of reading aloud books on comfort, hope, anxiety and vital signs in patients hospitalized in intensive care unit. This study was designed as a randomized controlled clinical trial. Data will be collected by using the Descriptive Characteristics Questionnaire, General Comfort Scale, Dispositional Hope Scale, State-Trait Anxiety Inventory, and the Vital Signs Monitoring Form.",[27,94,95,96],"Comfort","Anxiety","Vital Signs","2024-06-13",{"date":99,"type":38},"2024-06-20",{"date":101,"type":21},"2024-07-01",{"date":103,"type":21},"2024-12-31",{"name":105,"class":45},"TC Erciyes University"]