[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"horizontal-ridge-deficiency\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:horizontal-ridge-deficiency":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,40,70,101,123,145],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100599265","implant-phenotype-modification-via-gbr-and-adm-100599265",false,"NCT07082244","Implant Phenotype Modification Via GBR and ADM","Phenotype Modification Via Guided Bone Regeneration and Acellular Dermal Matrix Simultaneous to Delayed Implant Placement: A Double Arm Randomized Controlled Clinical Trial.","Inclusion Criteria:\n\n* Age ≥ 18 years.\n* Subjects with a physical status of systemically healthy or suffering from mild to moderate, but well-controlled disease; American Society of Anesthesiology (ASA) I or II.\n* Subjects must have one edentulous region, with at least 3 months of healing post-extraction, in the esthetic zone of the maxilla or the premolar and canine region of the mandible. This region includes the maxillary premolars, canines, and incisors.\n* Subjects must have a full mouth plaque and bleeding score of less than or equal to 20%, measured at four sites per tooth.\n* The patients should have a thin periodontal phenotype; bucco-lingual ridge thickness greater than 6mm.\n* Seibert class I deficiency (Seibert, 1983)\n* Patients willing to sign the informed consent.\n\nExclusion Criteria:\n\n* Presence of uncontrolled and\u002For untreated periodontal disease.\n* Patients currently smoking cigarettes, cannabis, and electronic cigarettes.\n* Subjects taking medications known to impact bone metabolism or have the capacity to affect wound healing. These drugs include bisphosphonates, corticosteroids, parathyroid hormone, RANKL inhibitors, past exposure to head and neck radiation, chemotherapy within the last 12 months, among others.\n* Subjects with systemic diseases that impact bone metabolism and wound healing. Namely, osteoporosis, osteopenia, hyperparathyroidism, Paget's disease.\n* Allergy to the graft materials.\n* Pregnant subjects or individuals who self-report as attempting to become pregnant.\n* Patient's unwilling to sign the informed consent.","ALL","18 Years",{"count":19,"type":20},40,"ESTIMATED","INTERVENTIONAL",[23],"NA","Single implant sites with bone loss can often be managed by bone grafting alone. The purpose of this study is to determine whether putting a soft tissue graft substitute over the bone graft will provide an increased benefit for improving the health, appearance, and stability of the bone and gums surrounding the implant.",[26],"Horizontal Ridge Deficiency","RECRUITING","2026-07-28",{"date":30,"type":31},"2026-07-30","ACTUAL",{"date":33,"type":31},"2025-06-01",{"date":35,"type":20},"2027-09-01",{"name":37,"class":38},"University of Michigan","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":4,"eligibilityCriteria":46,"healthyVolunteers":47,"sex":16,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":21,"phases":52,"briefSummary":53,"conditions":54,"keywords":56,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":39},"100531128","computer-guided-modified-ridge-splitting-versus-free-hand-technique-in-horizontal-deficiency-in-posterior-mandible-100531128","NCT06195761","Computer Guided Modified Ridge Splitting Versus Free Hand Technique in Horizontal Deficiency in Posterior Mandible","Radiographic Assessment of Computer Guided Modified Ridge Splitting Technique Versus Conventional Free Hand Technique in Management of Horizontal Deficiency in Posterior Mandible: a Randomized Control Clinical Trial","Inclusion Criteria:\n\n* posterior mandible with horizontal deficient alveolar ridge that is from 2 to 4 mm measured from the crest of the alveolar ridge buccolingually\n* Age range from 25-55 years. No sex predilection.\n* Patients free from any systemic conditions and bone metabolism diseases that might interfere with the surgical intervention, soft tissue or hard tissue healing.\n* Patients of adequate alveolar bone width.\n* Both genders males and females will be included\n* Normal vertical dimension with normal inter-arch space. The minimum number of missing teeth in the posterior mandible alveolar ridge is two adjacent anterior teeth\n\nExclusion Criteria:\n\n* Intra-bony lesions (e.g. cysts) or infections (e.g. abscess) that may retard the osteotomy healing.\n* Previous grafting procedures in the edentulous area.\n* General contraindications to implant surgery.\n* Subjected to irradiation in the head and neck area less than 1 year before implantation.\n* Untreated periodontitis.\n* Poor oral hygiene and motivation.\n* Uncontrolled diabetes.\n* Pregnant or nursing.\n* Immunosuppressed or immunocompromised\n* Heavy smokers\n* Patients undergo medication interfere with bone healing",true,"25 Years","55 Years",{"count":51,"type":20},18,[23],"To assess the accuracy of the computer assessed guides in horizontal bone augmentation achieved at posterior mandible using guided modified ridge splitting technique versus free hand modified ridge splitting technique",[55,26],"Horizontal Bone Augmentation",[57,58,59],"computer guided modified ridge splitting","computer guided modified cortical shell technique","guided modified ridge splitting in posterior mandible","NOT_YET_RECRUITING","2026-01-15",{"date":63,"type":31},"2026-01-16",{"date":65,"type":20},"2026-05-15",{"date":67,"type":20},"2026-06-15",{"name":69,"class":38},"Cairo University",{"id":71,"slug":72,"hasResults":11,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":4,"eligibilityCriteria":76,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":77,"targetDuration":4,"studyType":21,"phases":79,"briefSummary":80,"conditions":81,"keywords":83,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":39},"100597317","evaluation-of-horizontal-bone-gain-of-ridge-augmentation-using-customized-porous-zirconia-shell-100597317","NCT07056920","Evaluation of Horizontal Bone Gain of Ridge Augmentation Using Customized Porous Zirconia Shell.","Tomographic Evaluation of The Dimensional Changes After Horizontal Ridge Augmentation of the Lower Posterior Mandible Using a Novel Customized Porous Zirconia Shell Technique: Clinical Case Study.","Inclusion Criteria:\n\n* Age more than 18 years old.\n* Deficient lower posterior area (Seibert class I).\n* Enough inter-arch space for placement of implant-supported prosthesis.\n* Motivated the patient to have the treatment.\n* Good oral hygiene.\n\nExclusion Criteria:\n\n* Patient with systematic conditions that could interfere with healing process.\n* Pregnant females\n* Smokers.\n* Poor oral hygiene.",{"count":78,"type":20},10,[23],"Khoury technique, which employs autogenous bone blocks harvested from the patient, has been widely used for horizontal and vertical ridge augmentation. This method introduces critical limitations, including the technical complexity, morbidity associated with donor site harvesting, such as infection, neurosensory disturbances, and post-operative discomfort\n\nThis clinical case series aims to demonstrate how customized pours zirconium shell could be an alternative technique for ridge augmentation to overcome the limitations of Khoury shell technique.",[26,82],"Deficient Alveolar Bone",[84,85,86,87,88,89,90,91],"ridge augmentation","horizontal ridge augmentation","deficient alveolar ridge","zirconia","non resorbable membrane","khoury technique","zirconia membrane","lingual flap advancement","2025-07-28",{"date":94,"type":31},"2025-07-31",{"date":96,"type":31},"2025-03-15",{"date":98,"type":20},"2026-10-01",{"name":100,"class":38},"Ahmed Shawky",{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":4,"eligibilityCriteria":107,"healthyVolunteers":47,"sex":16,"minAge":108,"maxAge":109,"enrollmentInfo":110,"targetDuration":4,"studyType":21,"phases":112,"briefSummary":113,"conditions":114,"keywords":4,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":4},"100588485","radiographic-assessment-of-guided-cortical-shell-technique-for-horizontal-ridge-augmentation-100588485","NCT06942013","Radiographic Assessment of Guided Cortical Shell Technique for Horizontal Ridge Augmentation","Radiographic Assessment of Cortical Shell Technique For Horizontal Ridge Augmentation In The Anterior Mandible Using Full Digital Workflow Versus Free Hand Protocol: A Randomized Clinical Trial","Inclusion Criteria:\n\n* • Anterior mandible with horizontal deficient alveolar ridge that is from 2 to 4 mm measured from the crest of the alveolar ridge buccolingually.\n\n  * Class IV and V according to Cawood and Howell classification.\n  * No sex predilection.\n  * Patients free from any systemic conditions and bone metabolism diseases that might interfere with the surgical intervention, soft tissue or hard tissue healing.\n  * The minimum number of missing teeth in the anterior mandible alveolar ridge is two adjacent teeth.\n  * Normal vertical dimension with normal inter-arch space.\n\nExclusion Criteria:\n\n* • Intra-bony lesions (e.g. cysts) or infections (e.g. abscess) that may retard the osteotomy healing.\n\n  * General contraindications to implant surgery.\n  * Subjected to irradiation in the head and neck area less than 1 year before implantation.\n  * Untreated periodontitis.\n  * Poor oral hygiene and motivation.\n  * Uncontrolled diabetes.\n  * Pregnant or nursing females.\n  * Immunosuppressed or immunocompromised\n  * Heavy smokers\n  * Patients who undergo medication interfere with bone healing\n  * Previous grafting procedures in the edentulous area.","20 Years","60 Years",{"count":111,"type":20},20,[23],"The protocol outlines a randomized clinical trial comparing two surgical techniques for horizontal ridge augmentation in the anterior mandible:\n\nComputer-Guided Autogenous Cortical Shell Technique (using a patient-specific guide for precise placement).\n\nFree-Hand Autogenous Cortical Shell Technique (traditional approach without a guiding template).\n\nKey Points:\n\nThe study aims to determine which method provides better accuracy and bone volume stability.\n\nCone Beam CT scans (CBCT) will assess horizontal bone gain preoperatively and six months postoperatively.\n\nThe trial is conducted at Cairo University's Faculty of Dentistry. Participants: Patients with pure horizontal bone loss in the anterior mandible.\n\nOutcomes:\n\nPrimary: Bone width gain in millimeters. Secondary: Accuracy of augmentation and surgical time.\n\nMethodology:\n\nThe study group will use computer-designed surgical osteotomy guides to harvest and place bone grafts with improved precision.\n\nThe control group will rely on the conventional free-hand approach. Both groups will undergo bone grafting using autogenous cortical bone shells.\n\nData Collection \\& Analysis:\n\nParticipants will be randomized and blinded. Data will be analyzed using statistical methods to compare effectiveness.",[26],"2025-04-20",{"date":117,"type":31},"2025-04-24",{"date":119,"type":20},"2025-05-01",{"date":121,"type":20},"2026-09-01",{"name":69,"class":38},{"id":124,"slug":125,"hasResults":11,"nctId":126,"briefTitle":127,"officialTitle":128,"acronym":4,"eligibilityCriteria":129,"healthyVolunteers":47,"sex":16,"minAge":17,"maxAge":130,"enrollmentInfo":131,"targetDuration":4,"studyType":21,"phases":132,"briefSummary":133,"conditions":134,"keywords":135,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":137,"lastUpdatePostDateStruct":138,"startDateStruct":140,"completionDateStruct":142,"leadSponsor":144,"locationsCount":4},"100530396","evaluation-of-bone-regenerated-with-guided-bone-regeneration-gbr-using-polymethylmethacrylate-pmma-membrane-100530396","NCT06186232","Evaluation of Bone Regenerated With Guided Bone Regeneration (GBR) Using Polymethylmethacrylate (PMMA) Membrane","Evaluation Of Bone Regenerated After Guided Bone Regenration (GBR) Using Customized 3D Printed Polymethylmethacrylate (PMMA) Membrane in Horizontally Deficient Maxillary Aesthetic Zone","Inclusion Criteria:\n\n* Patients with edentulous area related to horizontally deficient aesthetic zone of maxilla.\n* Patients are physically healthy with no medical history of any systemic or local disease that would contraindicate ridge augmentation and\u002For implant surgery or complicate the healing process. (Severe liver or kidney disease, a history of head and neck radiotherapy, chemotherapy at the time of surgery, uncontrolled diabetes, active periodontal in the residual dentition, inflammatory or autoimmune disorders of the oral mucosa, poor oral hygiene, patient failure to cooperate, and any other disease condition contraindicating the oral surgery).\n* Non-smokers.\n* Free from temporomandibular joint disorders and abnormal oral habits such as bruxism.\n* The edentulous ridges were covered with optimal thickness of keratinized mucosa with no signs of inflammation, ulceration or scar tissue.\n* The occlusion shows sufficient inter-arch space for future prothesis.\n\nExclusion Criteria:\n\n* General contraindications to surgery.\n* Patients subjected to irradiation in the head and neck area less than 1 year before fixation.\n* Untreated periodontitis.\n* Poor oral hygiene.\n* Uncontrolled diabetes.\n* Pregnant or nursing.\n* Substance abuse.\n* Psychiatric problems or unrealistic expectations.\n* Severe bruxism or clenching.\n* Immunosuppressed or immunocompromised.\n* Treated or under treatment with intravenous amino-bisphosphonates.\n* Patients participating in other studies, if the present protocol could not be properly followed","50 Years",{"count":5,"type":20},[23],"To evaluate the quantity and quality of bone generated, radiographically and histomorphometrically, after guided bone regeneration (GBR) using a membrane of 3D printed custom made (PMMA) and subsequent stability of delayed implant placement.",[26],[136],"polymethylmethacrylate","2024-08-20",{"date":139,"type":31},"2024-08-21",{"date":141,"type":20},"2024-10-01",{"date":143,"type":20},"2025-12-01",{"name":69,"class":38},{"id":146,"slug":147,"hasResults":11,"nctId":148,"briefTitle":149,"officialTitle":150,"acronym":4,"eligibilityCriteria":151,"healthyVolunteers":47,"sex":16,"minAge":48,"maxAge":49,"enrollmentInfo":152,"targetDuration":4,"studyType":21,"phases":153,"briefSummary":154,"conditions":155,"keywords":156,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":158,"lastUpdatePostDateStruct":159,"startDateStruct":161,"completionDateStruct":163,"leadSponsor":165,"locationsCount":39},"100556787","ridge-splitting-using-autogenous-bone-wedge-versus-the-conventional-intercortical-augmentation-technique-in-horizontally-deficient-anterior-maxilla-100556787","NCT06529653","Ridge Splitting Using Autogenous Bone Wedge Versus the Conventional Intercortical Augmentation Technique in Horizontally Deficient Anterior Maxilla","Ridge Splitting Using Autogenous Bone Wedge Versus the Conventional Intercortical Augmentation Technique in Horizontally Deficient Anterior Maxilla A Randomized Clinical Trial","Inclusion Criteria:\n\n1. All patients possessed partially edentulous anterior maxillary ridge with the following criteria\n\n   1. The anterior maxillary vertical dimension was more than ten mm measured from the alveolar crest to the basal bone of the maxilla.\n   2. The horizontal alveolar dimension varies from 3-5 mm at the crest and 6-8 mm at the basal part of the ridge measured from the labial cortex to the lingual cortex.\n2. All patients were free from any medical conditions that may affect bone healing .\n3. No local pathosis that may interfere with bone healing.\n4. No previous grafting procedures at the indicated edentulous ridge.\n\n   \\-\n\n   Exclusion Criteria:\n\n1- Patients suffering from any systemic disease that may affect bone healing. 2- Patients with less than 3mm labio palatal alveolar ridge width. 3- Ridge with inadequate vertical bone height. 4- Presence of any local pathosis that may interfere with bone healing. 5- Patients unable to continue the whole follow up.\n\n\\-",{"count":111,"type":20},[23],"The current study aimed to evaluate both the quality and quantity of gained and maintained bone width after ridge splitting utilizing autogenic bone wedges versus mixed bone particles for horizontal ridge augmentation in the anterior esthetic zone.",[26],[157],"ridge splitting, bone wedge, mixed bone particles, horizontally deficient ridge, aesthetic zone, ridge augmentation.","2024-07-26",{"date":160,"type":31},"2024-07-31",{"date":162,"type":31},"2022-10-30",{"date":164,"type":20},"2024-12-30",{"name":69,"class":38}]