[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hypopigmentation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hypopigmentation":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":5},"100657537","fractional-co2-laser-vs-dermabrasion-with-5-fluorouracil-for-acquired-leukoderma-100657537",false,"NCT07837908","Fractional CO2 Laser vs Dermabrasion With 5-Fluorouracil for Acquired Leukoderma","Fractional Co2 Laser vs Dermabrasion 5-Flurouracil Delivery in Acquired Leukoderma: A Comparative Study","Inclusion Criteria:\n\n* Patients receiving topical treatment will be required to undergo a two-week washout period.\n* No sex predilection.\n* Cooperative patients.\n* Patients with non-vitiligo leukoderma, including post-burn leukoderma, post-inflammatory hypopigmentation, and stable hypopigmented scar.\n\nExclusion Criteria:\n\n* Vitiligo leukoderma.\n* History of bleeding disorder or current anticoagulant therapy.\n* Pregnancy or lactation.\n* Keloid scarring or hypertrophic scars.\n* Unrealistic expectations.\n* Laser therapy within one month prior to enrollment.\n* Koebnerization.\n* Photosensitivity.\n* Seizure disorders.\n* Active dermatosis or active bacterial, viral, or fungal cutaneous infection within the treatment area.","ALL","18 Years","75 Years",{"count":20,"type":21},16,"ESTIMATED","INTERVENTIONAL",[24],"NA","This randomized controlled prospective single-blinded comparative clinical study aims to compare the efficacy and safety of fractional carbon dioxide (CO2) laser therapy versus mechanical dermabrasion, both combined with topical 5-fluorouracil, in the treatment of acquired non-vitiligo leukoderma. The study will evaluate repigmentation, clinical improvement, patient satisfaction, and treatment-related adverse effects.",[27,28],"Leukoderma","Hypopigmentation","NOT_YET_RECRUITING","2026-09-20",{"date":32,"type":33},"2026-09-24","ACTUAL",{"date":35,"type":21},"2026-08-26",{"date":37,"type":21},"2027-08-26",{"name":39,"class":40},"Al-Azhar University","OTHER"]