[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"idiopathic-parkinsons-disease-and-lewy-body-disease\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:idiopathic-parkinsons-disease-and-lewy-body-disease":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":5},"100549845","single-center-study-of-gustation-in-idiopathic-parkinsons-disease-and-lewy-body-disease-using-gustatory-evoked-potential-analysis-100549845",false,"NCT06439355","Single-center Study of Gustation in Idiopathic Parkinson's Disease and Lewy Body Disease Using Gustatory Evoked Potential Analysis","PI-PEG","Inclusion Criteria:\n\nHealthy volunteers:\n\n* Person who has given written consent\n* Adult\n* Enrolled in the national register of healthy volunteers\n* Fasting \\> 2 hours before PEG measurement\n* Body Mass Index (BMI) \\\u003C 30 kg\u002Fm².\n* No cognitive complaints and normal neurological assessment\n\nPatients with idiopathic Parkinson's disease:\n\n* Person who has given written consent\n* Adult\n* Fasting \\> 2 hours before PEG measurement\n* Body Mass Index (BMI) \\\u003C 30 kg\u002Fm².\n* Diagnostic criteria for established or probable IPD\n\nPatients with Lewy body disease:\n\n* Person who has given written consent\n* Adult\n* Fasting \\> 2 hours prior to PEG measurement\n* Body Mass Index (BMI) \\\u003C 30 kg\u002Fm².\n* Diagnostic criteria for probable or possible LBD\n\nExclusion Criteria:\n\n* Non-affiliated to national health insurance\n* Person under legal protection (curatorship, guardianship)\n* Person subject to a court order\n* Pregnant, parturient or breast-feeding women\n* Major unable to give consent\n* MMSE score \\\u003C 15 and\u002For MoCA \\\u003C 10\n* Known infection with COVID-19 in the 6 months prior to inclusion\n* Active smoker (\\> 4 cigarettes per day on a regular basis)\n* Subject with pacemaker (contraindication for bioelectrical impedancemetry)\n* Diabetic (type 1 or type 2)\n* Taking medication (in progress at the time of the study) that interferes with gustation",true,"ALL","18 Years",{"count":20,"type":21},66,"ESTIMATED","INTERVENTIONAL",[24],"NA","The aim of the PI-PEG study is to explore the taste functions of the following 3 groups of participants:\n\n* healthy volunteers\n* patients with early Parkinson's disease\n* patients with incipient Lewy body disease.\n\nTo this end, the results obtained from taste evoked potentials in each of the 3 groups of participants will be compared with each other and with different nutritional, motor and cognitive data.\n\nThis study could reveal a difference in cortical processing of gustatory sensory information between patients who have had idiopathic Parkinson's disease progressing for 3 years or less, and patients who have had Lewy body disease progressing for 3 years or less. Indeed, a modification of taste evoked potentials (in terms of latencies) proportional to the degree of cerebral degeneration could be observed.",[27],"Idiopathic Parkinson's Disease and Lewy Body Disease","RECRUITING","2026-10-06",{"date":31,"type":32},"2026-10-07","ACTUAL",{"date":34,"type":32},"2024-05-27",{"date":36,"type":21},"2027-05",{"name":38,"class":39},"Centre Hospitalier Universitaire Dijon","OTHER"]