[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"implementation-research\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:implementation-research":35},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,11,0,[8,73,102,153,181,210,236,259,291,319,345],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":43,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":72},"100649333","prostate-cancer-risk-calculator-for-actionable-clinical-decision-making-in-nigeria-100649333",false,"NCT07733440","PROstate Cancer Risk Calculator for ACTionable Clinical Decision-making in Nigeria","Clinical Risk Calculator Validation and Implementation to Optimize Prostate Cancer Early Detection in Nigeria","PROACT","Inclusion Criteria:\n\n1. Training - Eligible primary care providers (for the training surveys) will be healthcare practitioners at community-level hospitals.\n2. Supported Risk Assessment\n\n(i) Eligible key informants will be eligible primary care providers who were trained and implemented the supported risk assessment and the targeted population of patient participants who received the supported risk assessment.\n\n(ii) Eligible patient participants (for the collection of observation data) will be the target population of adult males 40 - 79 years accessing provider services.\n\nExclusion Criteria:\n\n\\-",true,"MALE","18 Years",{"count":21,"type":22},89,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study is a pilot trial that builds on findings from the validation of prostate cancer risk calculators in Nigerian men. The goal of the overall study is to improve the early detection of prostate cancer in a high-risk population.\n\nThe main questions the validation study aims to answer are:\n\n1. How accurately do existing prostate cancer risk calculators identify Nigerian men with clinically significant prostate cancer?\n2. Will a new risk calculator designed for Nigerian men more accurately identify those with clinically significant prostate cancer?\n\nThe main questions the intervention study aims to answer is:\n\nWill the primary care provider-facing risk calculator be feasible and acceptable for primary care providers to implement?\n\nThe intervention trial will be piloted among participants in community-level hospitals in order to primarily assess implementation outcomes",[28,29,30,31,32,33,34,35,36,37,38,39,40,41,42],"Prostate Cancer","Risk Assessment","Clinical Decision Support Systems","Predictive Value of Tests","Models","Algorithms","Evidence-Based Practice","Implementation Research","Community Health Services","Primary Health Care","Biomarker","Prostate Specific Antigen","Global Health","Africa","Nigeria",[44,45,46,47,48,49,50,51,52,53,54,55,41,56,57,58,59,42],"Prostate cancer","early detection","prostate cancer screening","early diagnosis","prostate specific antigen","risk calculator","risk prediction model","diagnostic accuracy","validation","prostate biopsy","primary care","implementation science","precision prevention","clinically significant prostate cancer","clinical prediction model","community oncology","NOT_YET_RECRUITING","2026-07-24",{"date":63,"type":64},"2026-07-29","ACTUAL",{"date":66,"type":22},"2029-03",{"date":68,"type":22},"2029-08",{"name":70,"class":71},"Ahmadu Bello University","OTHER",1,{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":4,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":80,"minAge":19,"maxAge":4,"enrollmentInfo":81,"targetDuration":4,"studyType":23,"phases":83,"briefSummary":84,"conditions":85,"keywords":87,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":72},"100649019","implementation-of-acute-heart-failure-checklist-100649019","NCT07727304","Implementation of Acute Heart Failure Checklist","An Implementation Study to Improve Care of Patients With Acute Heart Failure in the Emergency Department","Inclusion Criteria:\n\n* All resident and staff physicians managing patients with AHF in the ED are the primary study participants and this includes emergency, medicine, cardiology, and hospitalists.\n* The patients that will be included are consecutive adults age \\>18 years and who present to the ED with recent onset of or recent increase in shortness of breath due to AHF, as determined by health records review.\n* Eligibility of patients will be reviewed by the blinded study Steering Committee.\n* Included will be both patients subsequently admitted to hospital and those discharged from the ED, as both will be impacted by the recommendations of the CAEP AHF Checklist.\n\nExclusion Criteria:\n\n* who do not fit the definition of AHF;\n* if the primary reason for the ED visit was not AHF (e.g. pneumonia, pulmonary embolism);\n* who have acute myocardial infarction (either ST elevation or non-ST elevation) diagnosed in the ED, because the primary problem for these patients is not heart failure and they require specialized treatment beyond the scope of the Checklist; or\n* who are considered terminal, with death expected within 60 days.","ALL",{"count":82,"type":22},5040,[25],"Patients with acute heart failure (AHF) commonly present to the emergency department (ED) with difficulty breathing and often have poor outcomes or death. Care of AHF is very complex and, unfortunately, there are no specific guidelines for how physicians should manage AHF in the ED. The investigators recently created the Canadian Association of Emergency Physicians (CAEP) AHF Best Practices Checklist, a concise document that provides specific guidance for ED care.\n\nOur ultimate goal is to conduct a 12-site cluster study to introduce the CAEP AHF Checklist in multiple EDs. Before the investigators can do so, it is essential to demonstrate feasibility in a smaller-scale study. Our objective for this application is to conduct an internal pilot study to demonstrate feasibility of measuring implementation outcomes and refine the protocol if necessary. The investigators will develop strategies to encourage successful adoption of the Checklist by physicians in the ED and allocate 4 large Ontario EDs to implement the Checklist for 1,700 adult AHF patients.\n\nThis study will be very important for patients and the healthcare system. If the investigators show that the CAEP AHF Checklist improves patient management and outcomes, this would lead to widespread uptake of the Checklist by all EDs in Canada.",[86,35],"Acute Heart Failure (AHF)",[88,89,90,91,92],"Best Practices Checklist","Acute Heart Failure","Emergency Department","Guidelines","Implementation","2026-07-22",{"date":95,"type":64},"2026-07-27",{"date":97,"type":22},"2026-08-01",{"date":99,"type":22},"2030-06-01",{"name":101,"class":71},"Ottawa Hospital Research Institute",{"id":103,"slug":104,"hasResults":11,"nctId":105,"briefTitle":106,"officialTitle":107,"acronym":4,"eligibilityCriteria":108,"healthyVolunteers":17,"sex":80,"minAge":19,"maxAge":4,"enrollmentInfo":109,"targetDuration":4,"studyType":111,"phases":4,"briefSummary":112,"conditions":113,"keywords":122,"overallStatus":143,"whyStopped":4,"lastUpdateSubmitDate":144,"lastUpdatePostDateStruct":145,"startDateStruct":147,"completionDateStruct":149,"leadSponsor":151,"locationsCount":72},"100646258","continuous-vital-sign-monitoring-in-a-surgical-ward-100646258","NCT07690267","Continuous Vital Sign Monitoring in a Surgical Ward","Continuous Vital Sign Monitoring in a Norwegian Hospital Surgical Ward: A Multi-Method Study of Patient Outcomes, Patient Safety Culture, and Nursing Staff Experiences","Inclusion Criteria:\n\n* Patients aged 18 years or older admitted to the gastro-surgical ward.\n* Healthcare professionals aged 18 years or older employed in the participating wards for survey participation.\n* Nursing staff with at least 6 months of work experience and experience using CVSM for participation in qualitative focus group interviews.\n\nExclusion Criteria:\n\n* Patients with delirium.\n* Patients with cognitive impairment interfering with sensor use.\n* Patients who decline participation.\n* Patients with allergy to electrode adhesives.",{"count":110,"type":22},9600,"OBSERVATIONAL","Unsafe patient care remains a major contributor to global morbidity and mortality. In surgical wards, postoperative patients are typically monitored intermittently using the National Early Warning Score (NEWS-2), leaving periods during which clinical deterioration may go undetected. Continuous vital sign monitoring (CVSM) using wearable sensors offers the potential for earlier identification of deterioration compared with intermittent assessments.\n\nCVSM was introduced in a hospital ward as part of a hospital-initiated pilot implementation and is used alongside standard monitoring with NEWS-2. The purpose of the study is to evaluate this implementation.\n\nThis observational study uses a pragmatic, quasi-experimental, multi-method, longitudinal design. The overall aims of the study are to evaluate the impact of CVSM implementation on patient outcomes, to explore healthcare professionals' perceptions of patient safety culture, turnover intention and pleasure of work, and to describe their experiences with implementation.",[114,115,116,117,118,119,120,121,92,35],"Patient Monitoring","Wearable Devices","Telemonitoring","Patient Safety","Patient Deterioration","Nurses","Healthcare Professionals","Work-related Outcomes",[123,124,125,116,126,127,128,129,119,130,131,132,133,134,92,135,136,137,138,139,140,141,142],"Continuous vital sign monitoring","Patient monitoring","Wearable devices","Patient safety","Patient deterioration","Early warning scores","National Early Warning Score (NEWS-2)","Healthcare professionals","Patient safety culture","Hospital Survey on Patient Safety Culture (HSOPSC 2.0)","Employee motivation","Work-related outcomes","Technology implementation","Quasi-experimental design","Focus group interview","qualitative study","SEIPS","Digital health","Gastro-surgical ward","Postoperative patients","RECRUITING","2026-07-08",{"date":146,"type":64},"2026-07-09",{"date":148,"type":64},"2025-09-01",{"date":150,"type":22},"2026-10-01",{"name":152,"class":71},"University Hospital, Akershus",{"id":154,"slug":155,"hasResults":11,"nctId":156,"briefTitle":157,"officialTitle":158,"acronym":159,"eligibilityCriteria":160,"healthyVolunteers":11,"sex":80,"minAge":19,"maxAge":4,"enrollmentInfo":161,"targetDuration":4,"studyType":111,"phases":4,"briefSummary":163,"conditions":164,"keywords":166,"overallStatus":143,"whyStopped":4,"lastUpdateSubmitDate":172,"lastUpdatePostDateStruct":173,"startDateStruct":175,"completionDateStruct":177,"leadSponsor":179,"locationsCount":72},"100621660","emergency-department-implementation-of-the-i-stat-alinity-traumatic-brain-injury-whole-blood-test-100621660","NCT07373509","Emergency Department Implementation of the i-STAT Alinity Traumatic Brain Injury Whole Blood Test","Effectiveness of the Traumatic Brain Injury Whole Blood Test on Improving Assessment and Triage for Patients With GCS 13-15 Presenting to Emergency Departments","EDI","Inclusion Criteria:\n\n1. Aged 18 or older\n2. Presenting to an enrolling ED with ED Arrival GCS of 13-15 following reported head blunt impact within 24 hours of injury\n3. Meets Department of Defense (DoD) definition of mTBI:\n\nA traumatically induced physiological disruption of brain function as a result of an external force that is indicated by new onset or worsening of at least one of the following clinical signs immediately following the event:\n\n1. Any alteration of mental status (e.g., feeling dazed, disoriented, or confused)\n2. Any period of loss of or a decreased level of consciousness, observed or self-report (loss of consciousness 30 minutes or less, an alteration of consciousness up to 24 hours)\n3. Any loss of memory for events immediately before or after the injury (post-traumatic amnesia up to 1-day post-injury)\n\nExclusion Criteria:\n\n1. Treating emergency department provider does not think a head CT scan is needed\n2. Inability to obtain results for iSTAT Alinity TBI test within 24 hours of injury\n3. Treating emergency department attending physician is not willing to participate\n4. Pre-existing neurologic condition\n5. Contraindication or inability to complete blood draw\n6. Significant polytrauma that, in the opinion of the principal investigators, could impact peripheral GFAP levels or require a full body scan\n7. History of penetrating TBI\n8. History of neurosurgical intervention for previous TBI\n9. Penetrating TBI for current injury\n10. Any history of brain surgery\n11. Any history of brain tumor\n12. Patients on psychiatric hold",{"count":162,"type":22},340,"The objective of this study is to identify determinants for implementing the i-STAT Alinity whole blood traumatic brain injury (TBI) test for its Food and Drug Administration (FDA)-indicated use and to evaluate other potential outcomes with clinical implications. The main questions it aims to answer are:\n\n1. Determine the number of patients with non-elevated (i.e., below clinical cutoff) whole blood iSTAT Alinity tests who also receive CT scans.\n2. What are the obstacles for using the i-STAT Alinity for its FDA-indicated use",[165,35],"TBI (Traumatic Brain Injury)",[167,168,169,170,171],"Concussion","Traumatic Brain Injury","CT scan","Blood Biomarker","i-STAT Alinity TBI Test","2026-07-01",{"date":174,"type":64},"2026-07-06",{"date":176,"type":64},"2026-01-13",{"date":178,"type":22},"2030-04",{"name":180,"class":71},"Shawn Eagle",{"id":182,"slug":183,"hasResults":11,"nctId":184,"briefTitle":185,"officialTitle":186,"acronym":187,"eligibilityCriteria":188,"healthyVolunteers":17,"sex":80,"minAge":189,"maxAge":4,"enrollmentInfo":190,"targetDuration":4,"studyType":23,"phases":192,"briefSummary":193,"conditions":194,"keywords":196,"overallStatus":143,"whyStopped":4,"lastUpdateSubmitDate":201,"lastUpdatePostDateStruct":202,"startDateStruct":204,"completionDateStruct":206,"leadSponsor":208,"locationsCount":72},"100642848","teen-helpline-motivational-interviewing-study-100642848","NCT07639736","Teen Helpline Motivational Interviewing Study","Using Performance Feedback and Facilitation to Integrate Motivational Interviewing in Teen Helpline Services","MI","Inclusion Criteria\n\nTeen Helpers\n\n* Current helpline peer helpers\n* Aged 14-19 years.\n* Provides assent and documented parental consent (when applicable).\n* Completes study measures prior to the first Motivational Interviewing (MI) training session.\n* Attends and completes assigned MI training activities.\n* Has access to technology required for online participation (computer, tablet, or smartphone with internet access; videoconferencing capability if needed).\n* Plans to continue helpline activities throughout the study period.\n\nTeen Users\n\n* Aged 13-19 years.\n* Current U.S. resident.\n* Has engaged in at least 20 back-and-forth text exchanges with a helpline volunteer.\n* Demonstrates active communication and engagement on the helpline platform.\n* Has access to technology required to complete online surveys and, if selected, interviews (computer, tablet, or smartphone with internet access).\n\nExclusion Criteria\n\nTeen Helpers\n\n\\- Plans to discontinue helpline activities within the next 8 months.\n\nTeen Users\n\n* Identified as currently experiencing acute suicide risk (i.e., assigned a \"high-risk\" flag by the helpline algorithm or identified as high risk by helpline staff).\n* Requires immediate crisis intervention or emergency services that could be disrupted by participation in the research study.","13 Years",{"count":191,"type":22},206,[25],"The proposed study will establish a foundation for research within peer-delivered helplines for teens. It aims to evaluate the impact of a Motivational Interviewing training at peer-to-peer helpline. The study will leverage emerging technologies to surmount the challenges of providing tailored training to a large and diverse mental health workforce at scale.\n\nAim 1: Adapt Motivational Interviewing (MI) strategies for use in a teen peer-delivered text-based digital helpline.\n\nAim 2: Co-design performance feedback (PF) and facilitated practice (FP) processes to support MI adherence among peer helpers.\n\nAim 3: Examine feasibility, acceptability, and initial outcomes in a pilot feasibility trial. Peer helpers (N=50) will be randomized to receive MI training or MI training + PF-FP.",[35,195],"Help Seeking",[197,198,199,200],"Adolescent mental health","Implementation Science","Motivational Interviewing","Mental health helplines","2026-06-22",{"date":203,"type":64},"2026-06-25",{"date":205,"type":64},"2025-08-28",{"date":207,"type":22},"2029-10-31",{"name":209,"class":71},"San Diego State University",{"id":211,"slug":212,"hasResults":11,"nctId":213,"briefTitle":214,"officialTitle":215,"acronym":216,"eligibilityCriteria":217,"healthyVolunteers":17,"sex":80,"minAge":218,"maxAge":4,"enrollmentInfo":219,"targetDuration":4,"studyType":111,"phases":4,"briefSummary":221,"conditions":222,"keywords":4,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":227,"lastUpdatePostDateStruct":228,"startDateStruct":230,"completionDateStruct":232,"leadSponsor":234,"locationsCount":72},"100636818","implementation-of-a-clinical-decision-support-system-in-primary-care-for-the-screening-and-assessment-of-frailty-in-patients-aged-65-and-over-100636818","NCT07570628","Implementation of a Clinical Decision Support System in Primary Care for the Screening and Assessment of Frailty in Patients Aged 65 and Over","Implementation of a Clinical Decision Support System in Primary Care for the Screening and Assessment of Frailty in Patients Aged 65 and Over: A Real-World Prospective Cohort Study","FRAGICLIC","Inclusion Criteria:\n\n* Patients aged 65 years or older\n* Patient or trusted person who provided oral non-opposition after receiving full information about the protocol\n* Managed by the general practitioner if the patient or nurse during the study period. If patients are assessed by a nurse : Patients whose general practitioner is a participating physician in the study\n\nExclusion Criteria:\n\n* Patients unable to express non-opposition or without a trusted person available to express non-opposition\n* Patients whose general practitioner (GP) is not a participating GP in the study\n* Patients or trusted persons who do not speak French","65 Years",{"count":220,"type":22},726,"This observational study aims to evaluate the real-life use of a digital tool (Fragiclic) by general practitioners (GPs) and nurses to screen and assess frailty in adults aged 65 and over. Frailty is a syndrome that increases the risk of loss of autonomy, falls, hospitalizations, or death. The tool includes simple screening questionnaires (such as SEGAm) and a comprehensive assessment (CGA - Comprehensive Geriatric Assessment) to better manage patients' health.\n\nThe main question it aims to answer is:\n\n* What proportion of patients aged 65 and over will benefit from frailty screening or assessment using Fragiclic over 12 months?\n\nA secondary question is\n\n\\- Does the use of Fragiclic reduce the risk of unplanned hospitalizations or death in these patients?\n\nFor the secondary question, researchers will compare patients who received screening or assessment (with or without a Personalized Care Plan (PCP)) to those who did not, to determine if Fragiclic improves their health outcomes.\n\nParticipants will not have additional tasks: Their GP or nurse will use Fragiclic during routine consultations. Some patients may be asked to provide information about their health or quality of life (via their healthcare provider).\n\nAll data will be collected anonymously and securely",[223,224,225,35,226],"Frailty at Older Adults","Primary Care","Geriatric Assessment","Interprofessional Collaboration","2026-05-11",{"date":229,"type":64},"2026-05-13",{"date":231,"type":22},"2027-01-02",{"date":233,"type":22},"2029-01-02",{"name":235,"class":71},"CNGE Conseil",{"id":237,"slug":238,"hasResults":11,"nctId":239,"briefTitle":240,"officialTitle":241,"acronym":4,"eligibilityCriteria":242,"healthyVolunteers":17,"sex":80,"minAge":19,"maxAge":4,"enrollmentInfo":243,"targetDuration":245,"studyType":111,"phases":4,"briefSummary":246,"conditions":247,"keywords":4,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":250,"lastUpdatePostDateStruct":251,"startDateStruct":253,"completionDateStruct":255,"leadSponsor":257,"locationsCount":72},"100633873","barriers-and-facilitators-to-nursing-record-with-ai-technology-application-100633873","NCT07532343","Barriers and Facilitators to Nursing Record With AI Technology Application","Barriers and Facilitators to Nursing Record With AI Technology Application: A Mixed Methods Study Using the Consolidated Framework for Implementation Research","Inclusion Criteria:\n\n* Nurses assigned to ward\n\nExclusion Criteria:\n\n* Nurses without record-keeping task\n* Those assigned to intensive care units, emergency room, or operating rooms",{"count":244,"type":22},271,"1 Year","The goal of this study is to examine the facilitators and barriers to the comprehensive implementation of AI technology in nursing documentation. The main questions it aims to answer are:\n\nWhat are facilitators to the comprehensive implementation of AI technology in nursing documentation? What are barriers to the comprehensive implementation of AI technology in nursing documentation? What strategies can help to fully utilize artificial intelligence technology in nursing documentation?",[35,248,249],"Artificial Intelligence (AI)","Nursing Documentation Burden","2026-04-08",{"date":252,"type":64},"2026-04-15",{"date":254,"type":22},"2026-05-01",{"date":256,"type":22},"2027-04-30",{"name":258,"class":71},"National Yang Ming Chiao Tung University Hospital",{"id":260,"slug":261,"hasResults":11,"nctId":262,"briefTitle":263,"officialTitle":264,"acronym":265,"eligibilityCriteria":266,"healthyVolunteers":11,"sex":80,"minAge":267,"maxAge":4,"enrollmentInfo":268,"targetDuration":4,"studyType":23,"phases":270,"briefSummary":271,"conditions":272,"keywords":279,"overallStatus":143,"whyStopped":4,"lastUpdateSubmitDate":281,"lastUpdatePostDateStruct":282,"startDateStruct":284,"completionDateStruct":286,"leadSponsor":288,"locationsCount":290},"100604546","supraglottic-airway-for-resuscitation-trial-100604546","NCT07150923","Supraglottic Airway for Resuscitation Trial","Comparing Two Multicomponent Strategies To Promote Supraglottic Airway Implementation During Neonatal Resuscitation","SUGAR","Population 1: Hospital Staff\n\nPopulation 1a: Clinical providers and administrators who complete study questionnaires\n\nClinical provider 1a inclusion criteria:\n\n* Employed full-time by the hospital, affiliated practice, or affiliated university in a role that involves newborn resuscitation\n* Fluent in English\n\nAdministrator 1a inclusion criteria\n\n* Oversee the care of newborns on a local level (e.g. nurse manager) or a hospital level (e.g. Chief Quality and Safety Officer)\n* Fluent in English\n\nClinical provider and administrator exclusion 1a criteria: No exclusion criteria\n\nPopulation 1b: Clinical providers who participate in qualitative interviews\n\nClinical provider 1b inclusion criteria:\n\n* Employed full-time by the hospital, affiliated practice, or affiliated university in a role that involves newborn resuscitation\n* Fluent in English\n\nClinical provider 1b exclusion criteria: No exclusion criteria\n\nPopulation 2: Patients who receive neonatal resuscitation at birth\n\nInclusion Criteria:\n\n* Inborn (not transferred to the hospital after birth)\n* ≥34 weeks' gestation at birth, based on best obstetrical estimate\n* Received PPV during neonatal resuscitation (as per provider's clinical assessment)\n\nExclusion Criteria:\n\n* Congenital diaphragmatic hernia\n* Airway anomalies","0 Days",{"count":269,"type":22},36503,[25],"This is a hybrid type 3 effectiveness-implementation parallel cluster randomized superiority trial designed to compare two strategies to promote early supraglottic airway (SA) rescue during neonatal resuscitation, with a focus on implementation outcomes.",[273,274,275,276,277,278,35],"Neonatal Resuscitation","Delivery Room Resuscitation","Positive Pressure Ventilation","Infant, Newborn","Supraglottic Airway","Laryngeal Mask Airways",[273,274,280,277,278,35,276],"Positive pressure ventilation","2026-02-26",{"date":283,"type":64},"2026-02-27",{"date":285,"type":64},"2026-01-01",{"date":287,"type":22},"2029-09",{"name":289,"class":71},"Children's Hospital of Philadelphia",30,{"id":292,"slug":293,"hasResults":11,"nctId":294,"briefTitle":295,"officialTitle":296,"acronym":297,"eligibilityCriteria":298,"healthyVolunteers":11,"sex":80,"minAge":299,"maxAge":4,"enrollmentInfo":300,"targetDuration":4,"studyType":23,"phases":302,"briefSummary":303,"conditions":304,"keywords":308,"overallStatus":143,"whyStopped":4,"lastUpdateSubmitDate":311,"lastUpdatePostDateStruct":312,"startDateStruct":314,"completionDateStruct":315,"leadSponsor":317,"locationsCount":72},"100600004","bridge-blood-pressure-reduction-and-intervention-delivery-via-group-engagement-100600004","NCT07091851","BRIDGE: Blood Pressure Reduction and Intervention Delivery Via Group Engagement","A Hybrid Type 1 Randomized Trial for Improved Post-Stroke Hypertension: This Study Aims to Examine the Impact of Group Medical Visits and Home Blood Pressure Monitoring Versus Home Blood Pressure Monitoring Alone on the the Impact of Hypertension in Those With Recent Stroke.","BRIDGE","Inclusion Criteria:\n\n* Incident, mild to moderate, ischemic or hemorrhagic stroke (NIHSS≤15, ICH score≤3)\n* history or new diagnosis of hypertension\n* ability to read and speak English\n* internet access\n* established primary care physician at MGH\n\nExclusion Criteria:\n\n* severe stroke (NIHSS\\>15, ICH score\\>3)\n* discharge location to inpatient rehabilitation or skilled nursing facility\n* dementia\n* subjects with moderate to severe aphasia without a caregiver to consent on their behalf","35 Years",{"count":301,"type":22},50,[25],"The investigators want to improve care for people who have had a stroke. High blood pressure is the leading cause for having a second stroke and can lead to poor brain health. The goal of this study is to compare two new ways of lowering blood pressure. The first way is to help people check their blood pressure at home. The second way is to bring people together and learn about blood pressure in a group setting. The study team thinks that using both methods together will make it easier to lower blood pressure after a stroke. The study team needs this study to test these two methods together in people who have had a stroke. The investigators believe this is an important study because having high blood pressure makes having another stroke very likely. Therefore, the investigators want to lower blood pressure in people with strokes to keep their brains as healthy as possible and to help with stroke recovery.",[305,306,307,35],"Stroke","Hypertension","Home Blood Pressure Monitoring",[309,310,55],"stroke","post-stroke hypertension","2025-09-22",{"date":313,"type":64},"2025-09-25",{"date":311,"type":64},{"date":316,"type":22},"2028-04-30",{"name":318,"class":71},"Massachusetts General Hospital",{"id":320,"slug":321,"hasResults":11,"nctId":322,"briefTitle":323,"officialTitle":324,"acronym":4,"eligibilityCriteria":325,"healthyVolunteers":11,"sex":80,"minAge":19,"maxAge":4,"enrollmentInfo":326,"targetDuration":4,"studyType":23,"phases":327,"briefSummary":328,"conditions":329,"keywords":330,"overallStatus":143,"whyStopped":4,"lastUpdateSubmitDate":336,"lastUpdatePostDateStruct":337,"startDateStruct":339,"completionDateStruct":341,"leadSponsor":343,"locationsCount":72},"100587066","implementation-of-naturalistic-developmental-behavioral-intervention-ndbi-through-coaching-caregivers-of-young-autistic-children-100587066","NCT06923553","Implementation of Naturalistic Developmental Behavioral Intervention (NDBI) Through Coaching Caregivers of Young Autistic Children","NDBI Training and Coaching","Inclusion Criteria:\n\n1. Caregivers: Primary caregivers of young children aged 0-5 who meet one of the following conditions: (1) diagnosed with autism spectrum disorder, (2) diagnosed with developmental delay, and (3) diagnosed with a developmental disability. Eligible caregivers include: (1) parents, (2) grandparents, (3) legal guardians. All caregivers must be at least 18 years old and must be of Korean descent.\n2. Clinicians: The clinicians must hold a current Board Certified Behavior Analyst (BCBA) certification and must have experience delivering behavioral intervention and caregiver training for children aged 0-5.\n3. Children: Children in this study must be between 0-5 years old and must have a formal medical diagnosis confirming one of the following conditions: (1) autism spectrum disorder (ASD), (2) developmental delay, or (3) developmental disability.\n\nExclusion Criteria:\n\n1. Caregivers: Caregivers will be excluded if they (1) primarily care for children over the age of 6, (2) are not Korean speakers, or (3) are unable to fully participate in study activities, such as watching training videos, recording parent-child interactions, or completing required questionnaires.\n2. Clinicians: Clinicians will be excluded if they (1) do not hold a valid Board Certified Behavior Analyst (BCBA) certification, (2) lack experience in providing behavioral intervention and caregiver training for children aged 0-5, or (3) only work with children over the age of 6.\n3. Children: Children will be excluded if they (1) are older than 5 years, (2) do not have a formal medical diagnosis confirming autism spectrum disorder, developmental delay, or developmental disability.",{"count":301,"type":22},[25],"Naturalistic developmental behavioral interventions (NDBIs) are a newer class of evidence-based interventions for young autistic children to promote their positive developmental or behavioral outcomes. These are often delivered by family members or other natural change agents given the emphasis on naturalistic transactions between an adult and a child. Despite the emerging evidence, there are practical difficulties that hinder wider dissemination and implementation of NDBIs, including low level of access to some of these branded, packaged NDBIs. To mitigate these difficulties related to access, we have created a series of video modules that demonstrate nine commonly used core components in NDBI strategies. In this study, caregivers will receive training and coaching using these modules and both synchronous and asynchronous coaching from a clinician. In this type 1 hybrid implementation trial, there are two groups of participants: (1) caregivers of young autistic children or children with other developmental disabilities\u002Fdelays, (2) children, and (3) clinicians. Caregivers will meet with clinicians virtually weekly to (a) watch the newly developed NDBI videos that demonstrate the strategy use, (b) discuss how this might be applied to their own child, (c) receive individualized homework planning, (d) record and upload videos of their practice of strategy use with their own child, and (e) review the videos with clinicians to receive individualized feedback on their strategy use. This will occur for 10 weeks. Each session will be video recorded to assess the clinicians' intervention fidelity. After 10 weeks, pre-post tests will be conducted to assess parents' confidence on implementing these strategies, their child's social communication, and satisfaction of providers and caregivers. Qualitative data will also be collected via interviews with some selected participants to gain a deeper understanding of their perceptions.",[35],[331,332,333,334,335],"Hybrid type 1","autism","NDBI","family coaching","underserved families","2025-04-04",{"date":338,"type":64},"2025-04-11",{"date":340,"type":22},"2025-04-01",{"date":342,"type":22},"2026-12-31",{"name":344,"class":71},"University of Texas at Austin",{"id":346,"slug":347,"hasResults":11,"nctId":348,"briefTitle":349,"officialTitle":350,"acronym":351,"eligibilityCriteria":352,"healthyVolunteers":11,"sex":80,"minAge":19,"maxAge":4,"enrollmentInfo":353,"targetDuration":4,"studyType":23,"phases":355,"briefSummary":356,"conditions":357,"keywords":361,"overallStatus":143,"whyStopped":4,"lastUpdateSubmitDate":367,"lastUpdatePostDateStruct":368,"startDateStruct":370,"completionDateStruct":372,"leadSponsor":374,"locationsCount":72},"100537032","implementing-proms-and-prems-in-routine-clinical-care-assessment-of-requirements-and-impact-100537032","NCT06272552","Implementing PROMs and PREMs in Routine Clinical Care: Assessment of Requirements and Impact","Implementing PROMs and PREMs in Routine Clinical Care: Assessment of Requirements and Impact.","PROMs & PREMs","Inclusion Criteria:\n\n* Being an active patient of the nephrology service, prostate cancer service, breast cancer service, or bariatric surgery service\n* In possession of an email account and having basic knowledge of how to manage emails\n* In possession of a smartphone, computer, or tablet with access to the Internet\n* Fluent and able to read in Spanish\n\nExclusion Criteria:\n\n\\- Under 18 years of age",{"count":354,"type":22},1440,[25],"There has been increasing interest in the use of patient-reported outcomes and experience measures (PROMs and PREMs) in clinical practice; yet few empirical studies have been conducted to evaluate the usefulness of such implementation.\n\nObjective: To evaluate the efficacy of the implementation of PROMs and PREMs in routine clinical care for improving health outcomes and satisfaction with health management.\n\nDesign: Randomized control trial. Setting: In and outpatient departments of a public hospital in Spain.\n\nParticipants: 1,440 adult patients managed for breast cancer, prostate cancer, chronic kidney disease, or bariatric surgery.\n\nIntervention: Patients will monthly complete, through an App from their smartphones, PROMs and PREMs (arm A, n=480), or only PREMs (arm B, n=480). Responses to PROMs will be transformed into a graphic summary, accessible for physicians and patients at the follow-up visits of the project (9 and 18 months after recruitment).\n\nMain outcome measures: Comparison of change among arms on the assessment variables - such as health-related quality of life (EQ-5D-5L), satisfaction with care, or patient-professionals communication. These constructs will be measured at recruitment and at follow up visits for all patients, regardless of their arm allocation (arm C would only be administered these questionnaires, without intervention, n=480).\n\nExpected results: Incorporating PROMs and PREMs in routine clinical care may improve patients\\' and health professionals\\' experiences on health care, as well as improve patients\\' health.",[358,359,35,360],"PROMs","PREMs","Impact Evaluation",[362,35,363,358,359,364,365,366],"PRMs Implementation","Implementation evaluation","Impact evaluation","RCT","Health Services Research","2024-02-21",{"date":369,"type":64},"2024-02-22",{"date":371,"type":64},"2023-10-25",{"date":373,"type":22},"2027-10",{"name":375,"class":71},"Parc de Salut Mar"]