[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"incisional-hernia-of-anterior-abdominal-wall\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:incisional-hernia-of-anterior-abdominal-wall":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100660005","phasix-mesh-underlay-during-loop-ileostomy-closure-100660005",false,"NCT07871630","Phasix Mesh Underlay During Loop Ileostomy Closure","Phasix Mesh Underlay During Loop Ileostomy Closure: A Single Center Prospective Trial","Inclusion Criteria:\n\n* Age 18 years or older\n* History of creation of a loop ileostomy\n* Presenting for loop ileostomy closure\n* BMI greater than 25\n\nExclusion Criteria:\n\n* Patients involved in other clinical research trials\n* Unable to close posterior rectus sheath\n* Cannot consent or are unwilling to consent\n* Belong to a vulnerable population group such as pediatric patients, prisoners, pregnant patients, individuals with limited English proficiency, visually impaired individuals, or non-readers\n* Patients with prohibitive medical risk including congestive heart failure, renal failure, or liver failure, based on the discretion of the principal investigator and operating surgeon\n* Allergy to tetracycline hydrochloride or kanamycin sulfate\n* Women planning to become pregnant during study participation has context menu","ALL","18 Years",{"count":19,"type":20},65,"ESTIMATED","INTERVENTIONAL",[23],"NA","This prospective study will evaluate whether placement of long-acting absorbable Phasix mesh during loop ileostomy closure reduces the development of an incisional hernia at the ileostomy closure site in patients with a BMI greater than 25. Participants will undergo mesh-reinforced closure and will be followed for two years after surgery. The primary outcome is development of an incisional hernia at the ileostomy closure site, confirmed by CT imaging at two years.",[26],"Incisional Hernia of Anterior Abdominal Wall",[28,29,30,31,32,33],"Loop ileostomy closure","Phasix mesh","prophylactic mesh","Mesh reinforcement","Ileostomy site hernia","Incisional Hernia","NOT_YET_RECRUITING","2026-10-08",{"date":37,"type":38},"2026-10-13","ACTUAL",{"date":40,"type":20},"2026-10-30",{"date":42,"type":20},"2028-10-30",{"name":44,"class":45},"Corewell Health West","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":54,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":21,"phases":57,"briefSummary":58,"conditions":59,"keywords":60,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":4},"100401839","study-on-the-efficacy-of-prophylactic-on-lay-mesh-in-preventing-post-operative-hernia-in-liver-transplant-patients-100401839","NCT04512469","Study on the Efficacy of Prophylactic on Lay Mesh in Preventing Post-operative Hernia in Liver Transplant Patients","A Randomized Controlled Trial Examining the Efficacy of Prophylactic on Lay Mesh Versus Standardized Fascial Closure on Ventral Incisional Hernia Rates in Liver Transplant Patients","Inclusion Criteria:\n\n• All patients above 18 years of age undergoing liver transplantation\n\nExclusion Criteria:\n\n* Non consenting patients\n* patients with skin or deep tissue infections at the time of surgery\n* prior mesh infection from hernia repair will be excluded\n* entry into the gastro-intestinal system (i.e., need for hepaticojejunostomy for transplantation versus just a standard biliary-biliary anastomosis)\n* prior biliary stent (causes colonization of the biliary track and increases surgical site infection)\n* patients that are unstable, requiring pressors, or required \\>4 units of packed red blood cell transfusions intra-operatively will be excluded as to not prolong surgical time.\n* Pregnant women\n* Prior incisional hernia\u002Fhistory of IH and repair\n* Death within 1-year\n* Insufficient follow up\n* Connective tissue disorders\n* Prior significant wound dehiscence or infection\n* Spontaneous bacterial peritonitis\n* Primary sclerosing cholangitis (requires roux en y reconstruction thereby entry into the Alimentary track)",true,{"count":56,"type":20},100,[23],"Study Design: Single-blinded, randomized, prospective clinical trial. Study Population: End-stage liver disease patients' candidates for liver transplantation.\n\nStudy procedures: Consenting patients will be divided into two matched groups:\n\n1. CONTROL group - receiving a standard running fascial closure with PDS suture\n2. TREATMENT group - receiving a standard running fascial closure with PDS suture PLUS a low molecular weight mesh. The mesh will be secured to the fascia extending 3 cm from the incisional site.\n\nThere will be no modifications to routine post-operative wound care in both groups. However, the treatment group will have an additional drain placed at the incision site compared to the control group to reduce the risk of a seroma from placement of the mesh. Wound dressing will be removed on post-op day 2 and the wound will be assessed. Re-application of the dressing will occur thereafter until proper healing of the incision.\n\nAn abdominal ultrasound will be done on all study participants at the 1- and 2-year mark postoperatively to look for objective evidence of a ventral incisional hernia. A CT scan will be performed if the abdominal ultrasound findings are inconclusive.",[26],[61,62],"liver transplant","incisional hernia","2020-08-12",{"date":65,"type":38},"2020-08-13",{"date":67,"type":20},"2020-09",{"date":69,"type":20},"2026-09",{"name":71,"class":45},"London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's"]