[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"induced-hypotension\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:induced-hypotension":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":34,"leadSponsor":36,"locationsCount":4},"100645546","effect-of-controlled-hypotension-on-gfap-and-cognition-in-rhinoplasty-100645546",false,"NCT07699133","Effect of Controlled Hypotension on GFAP and Cognition in Rhinoplasty","Evaluation of the Effect of Controlled Hypotension During Elective Rhinoplasty on Serum Glial Fibrillary Acidic Protein (GFAP) and Cognitive Functions","Inclusion Criteria:\n\n* Scheduled for elective rhinoplasty or septorhinoplasty under general anesthesia.\n* ASA physical status I or II.\n* Literate and willing to provide written informed consent.\n\nExclusion Criteria:\n\n* History of neurological (e.g., cerebrovascular event, epilepsy) or psychiatric diseases.\n* Total septal reconstruction requiring costal (rib) cartilage grafts.\n* Expected surgical duration exceeding 3 hours.\n* Preoperative severe cognitive impairment.\n* Pregnancy or lactation.","ALL","18 Years","50 Years",{"count":20,"type":21},40,"ESTIMATED","OBSERVATIONAL","This prospective observational study aims to evaluate the neurological safety of controlled hypotension (Mean Arterial Pressure 50-65 mmHg) during elective rhinoplasty. The investigators will assess whether this standard intraoperative hypotensive strategy causes cellular stress by measuring serum Glial Fibrillary Acidic Protein (GFAP) levels and early postoperative cognitive changes using the Montreal Cognitive Assessment (MoCA) test.",[25,26,27],"Nasal Septum Deviation","Rhinoplasty","Induced Hypotension","NOT_YET_RECRUITING","2026-07-10",{"date":31,"type":32},"2026-07-14","ACTUAL",{"date":29,"type":21},{"date":35,"type":21},"2027-03-30",{"name":37,"class":38},"Kahramanmaras Sutcu Imam University","OTHER"]