[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"initial-dental-caries\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:initial-dental-caries":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100647540","remineralizing-effect-of-nano-eggshell-casein-phosphopeptide-amorphous-calcium-phosphate-cpp-acp-and-sodium-fluoride-on-initial-enamel-caries-100647540",false,"NCT07711132","Remineralizing Effect of Nano-eggshell, Casein Phosphopeptide Amorphous Calcium Phosphate (CPP-ACP), and Sodium Fluoride on Initial Enamel Caries","Remineralizing Effect of Nano-eggshell, Casein Phosphopeptide Amorphous Calcium Phosphate (CPP-ACP), and Sodium Fluoride on Initial Enamel Caries: Randomized Controlled Trial","CPP-ACP","Inclusion Criteria:\n\nPatients' ages should be 15-20 years. Patients should have at least three to four teeth with ICDAS II scores of 1-2. Patients should have moderate-to-high caries risk.\n\nExclusion Criteria:\n\nKnown hypersensitivity to one of the components of the material under study. Systemic disorders or medication interfering with normal salivary flow.","ALL","15 Years","20 Years",{"count":21,"type":22},90,"ESTIMATED","INTERVENTIONAL",[25],"NA","This randomized controlled clinical trial aims to evaluate and compare the remineralizing effect of nano-eggshell varnish, CPP-ACP paste (GC Tooth Mousse), and sodium fluoride varnish on initial enamel caries among adolescents aged 15-20 years.\n\nParticipants will be randomly allocated into three groups. Remineralization and caries activity will be assessed using DIAGNOdent readings, International Caries Classification and Management System (ICCMS) criteria, and the decayed, missed, and filled surfaces (DMFS) index over a 12-month follow-up period.",[28],"Initial Dental Caries",[30,31,32],"Remineralization","Nano eggshell","initial enamel caries","RECRUITING","2026-07-14",{"date":36,"type":37},"2026-07-17","ACTUAL",{"date":39,"type":37},"2025-12-20",{"date":41,"type":22},"2026-12-20",{"name":43,"class":44},"Mansoura University","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":17,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":23,"phases":57,"briefSummary":58,"conditions":59,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":45},"100601508","clinical-evaluation-of-remineralizing-potential-of-remineralizing-agents-on-wsls-managment-100601508","NCT07111403","Clinical Evaluation of Remineralizing Potential of Remineralizing Agents on WSLs Managment","Remineralization Potential of Different Remineralizing Agents on Initial Enamel Caries: Laboratory Evaluations and Two-year Randomized Clinical Trial","Inclusion Criteria:\n\n* Participants should have at least one visible initial enamel caries in the permanent teeth\n* Only lesions with ICDAS II score of 1 or 2 could be included\n* The patients must have good oral hygiene\n\nExclusion Criteria:\n\n* patients receiving tetracyclines, any other medication known to stain teeth - Patients had fluoride application less than 3 months before the study\n* Teeth which have microcavities or dentinal involvement due to loss of enamel - Teeth that have discoloration, enamel hypoplasia or fluorosis.","14 Years","26 Years",{"count":56,"type":22},120,[25],"To evaluate and compare the clinical effect of four different remineralizing agents on initial enamel caries after a two years follow up.",[28,60],"White Spot Lesion of Tooth","2025-08-07",{"date":63,"type":37},"2025-08-13",{"date":65,"type":37},"2024-09-10",{"date":67,"type":22},"2026-09-17",{"name":43,"class":44}]