[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"innovative-procedures\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:innovative-procedures":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,85],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100651008","innovative-tube-trabeculectomy-for-advanced-and-refractory-glaucoma-a-randomized-controlled-trial-100651008",false,"NCT07755761","Innovative Tube Trabeculectomy for Advanced and Refractory Glaucoma: A Randomized Controlled Trial","A Prospective, Randomized, Controlled, Single-Center Clinical Trial to Evaluate the Efficacy and Safety of Innovative Tube Trabeculectomy Compared to Conventional Trabeculectomy in Patients With Advanced and Refractory Glaucoma","ITT-RCT","Inclusion Criteria:\n\n\\- • Diagnosis of advanced or refractory primary open-angle glaucoma (POAG) or secondary open-angle glaucoma (excluding neovascular glaucoma).\n\n* Intraocular pressure (IOP) \\> 21 mmHg despite maximal tolerated medical therapy or previous failed glaucoma surgery.\n* Best corrected visual acuity (BCVA) of 20\u002F400 or better.\n* Capable of providing informed consent\n\nExclusion Criteria:\n\n* Previous incisional glaucoma surgery in the study eye (except for prior failed trabeculectomy in the refractory group).\n* Neovascular glaucoma or other forms of secondary glaucoma that may significantly impact wound healing (e.g., uveitic glaucoma).\n* Significant ocular comorbidities that may confound outcome assessment (e.g., severe corneal disease, retinal detachment).\n* Pregnancy or lactation.\n* Participation in another clinical trial within 30 days prior to enrollment.","ALL","18 Years",{"count":20,"type":21},116,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to compare the efficacy and safety of a novel surgical technique, Innovative Tube Trabeculectomy (ITT), against conventional trabeculectomy in patients with advanced and refractory glaucoma. ITT incorporates a unique preoperative regimen and surgical modifications, including a deep extended scleral tunnel, X-shaped non-absorbable suture, and a nasolacrimal tube implant, designed to enhance aqueous humor outflow and reduce postoperative fibrosis. Participants will be randomized to receive either ITT or conventional trabeculectomy and followed for 12 months to assess intraocular pressure control, medication use, complication rates, and bleb morphology.",[27,28,29],"Glaucoma","Trabeculectomy","Innovative Procedures",[31,32,33],"glaucoma","innovative","tube trabeculectomy","RECRUITING","2026-08-05",{"date":37,"type":38},"2026-08-10","ACTUAL",{"date":40,"type":38},"2026-08-01",{"date":42,"type":21},"2028-08-01",{"name":44,"class":45},"Benha University","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":17,"minAge":55,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":69,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":46},"100588234","novel-medical-device-for-pharmacological-therapy-100588234","NCT06938750","Novel Medical Device for Pharmacological Therapy","A Pilot Study of a Novel Medical Device for Pharmacological Therapy: The SecHold Device","Sechold","Inclusion Criteria:\n\n* patients admitted to the intensive care unit\n* patients with authorization to take part in the study\n\nExclusion Criteria:\n\n* Patients with pre-existing medical conditions: Patients with diseases affecting coagulation, such as hemophilia or thrombocytopathies, could be excluded.\n* Active infection patients: Any patient with vascular access site infections or systemic infections may be excluded to avoid complications.\n* Inability to give informed consent: Patients who are unable to understand or consent to participate in the study.","1 Year",{"count":57,"type":21},262,[24],"Background: Different co-creation methods were used to design and prototype a new fixative device for multiple intravenous therapies with the ability to control and identify the pharmacological therapy administered to a patient. Objectives: To validate a newly created device for the reduction of complications related to the use of intravenous therapy Methods: A multidisciplinary team composed of eight professionals specializing in the field of critical care and an engineering professional in industrial design was responsible for collecting, evaluating, and materializing the ideas and needs arising from clinical practice in a device that met the standards of the same.",[61,62,63,64,65,66,67,68,29],"Vascular Access","Vascular Access Complication","Vascular Access Complications","Catheter Malfunction","Catheter Infection","Therapeutic Drug Management","Nurse","Nurse Based Care Management",[70,71,72,73,74,75],"VASCULAR ACCESS","CATHETER","THERAPY","COMPLICATION","DEVICE","CENTRAL VASCULAR ACCESS","2025-04-14",{"date":78,"type":38},"2025-04-22",{"date":80,"type":38},"2023-01-20",{"date":82,"type":21},"2026-09-20",{"name":84,"class":45},"Fundacion Miguel Servet",{"id":86,"slug":87,"hasResults":11,"nctId":88,"briefTitle":89,"officialTitle":89,"acronym":90,"eligibilityCriteria":91,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":92,"targetDuration":94,"studyType":95,"phases":4,"briefSummary":96,"conditions":97,"keywords":4,"overallStatus":99,"whyStopped":4,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":109},"100561416","french-prospective-cohort-of-innovative-endoscopic-interventions-in-expert-centers-100561416","NCT06589882","French Prospective Cohort of Innovative Endoscopic Interventions in Expert Centers","CoPPInE","Inclusion Criteria:\n\n* Patients \\> 18 yo\n* Patient able to give consent\n* Patient with innovative endoscopy\n\nExclusion Criteria:\n\n* Opposition to participation in the present project to be notified in the file\n* Patient under court protection",{"count":93,"type":21},10000,"10 Years","OBSERVATIONAL","The creation of a multi-center French cohort pooling data from innovative endoscopies carried out in France every year would make it possible to produce excellent scientific results and analyze on a large scale the results of our current practices.",[98,29],"Endoscopy","NOT_YET_RECRUITING","2024-09-06",{"date":102,"type":38},"2024-09-19",{"date":104,"type":21},"2024-10-01",{"date":106,"type":21},"2034-09-01",{"name":108,"class":45},"Centre Hospitalier Universitaire de Nīmes",2]