[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"instability-joint\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:instability-joint":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,45,69,99],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100648753","comparative-effects-of-closed-kinetic-chain-exercises-and-throwers-ten-exercises-in-glenohumeral-instability-100648753",false,"NCT07724977","Comparative Effects of Closed Kinetic Chain Exercises and Thrower's Ten Exercises in Glenohumeral Instability","Comparative Effects of Closed Kinetic Chain Exercises and Thrower's Ten Exercises on Pain, Mobility and Performacne in Glenohumeral Instability Among Bowlers","Inclusion Criteria:\n\n* Male bowlers are included in this study\n* Healthy athletes with age group 16-25y\n* Athletes having 2 years of bowling experience\n\nExclusion Criteria:\n\n* Bowlers with prior history of trauma and shoulder injuries from past 6 months bowlers with any medical issues such as hypertension, any , neurological , cardiovascular and psychological problems\n* if athlete suffered from any upper extremity orthopedic or musculoskeletal injury from last 6 months","MALE","16 Years","25 Years",{"count":20,"type":21},40,"ESTIMATED","INTERVENTIONAL",[24],"NA","The study is randomized and single-blinded. Ethical approval is taken from ethical committee of Riphah International University, Lahore. Participants who meet the inclusion criteria will be enrolled and allocated in group A \\& B through sealed envelope method by Non-probability Convenient random sampling technique. Subjects in Group A will receive closed kinetic chain exercises. Group B will receive thrower's ten exercises.",[27],"Instability, Joint",[29,30,31],"closed chain kinetic exercises","thrower's ten exercises","instability","RECRUITING","2026-08-10",{"date":35,"type":36},"2026-08-12","ACTUAL",{"date":38,"type":36},"2025-10-15",{"date":40,"type":21},"2026-08-30",{"name":42,"class":43},"Riphah International University","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":52,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":22,"phases":57,"briefSummary":58,"conditions":59,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":44},"100649104","effect-of-core-stability-training-with-foot-exercises-in-chronic-ankle-instability-patients-100649104","NCT07731035","Effect of Core Stability Training With Foot Exercises in Chronic Ankle Instability Patients","Effect of Core Stability Training With Foot Exercises on Proprioception, Balance and Foot Function in Chronic Ankle Instability Patients","Inclusion Criteria:\n\nSubjects will be selected from the outpatient clinic of Delta University hospital, Dakahlia, Egypt. 2. Both male \\& female genders aged between 18 and 44 years. 3. Participants should have a history of at least one significant ankle sprain; the initial sprain must have occurred at least 12 months prior to the study enrolment and was associated with inflammatory symptoms (pain, swelling) 4. Patients having Scores on the Cumberland ankle instability tool of 24 or below 5. Participants should report at least 2 episodes of 'giving way' in the 6 months prior to the study enrolment. Episodes of giving way will be described as an incident in which the rearfoot suddenly rolled, felt weak, or lost stability; however, the individual did not sustain an ankle sprain and will have been able to continue with normal function after the incident 6. Body mass index for all groups will be ranged from 18.8-29 kg\u002Fm²\n\nExclusion Criteria:\n\n1. history of lower extremity surgery, lower extremity fractures, and immobilization of foot or ankle for 48 hr or longer within the previous 6 months\n2. Conditions other than ankle sprain that affect balance or they are receiving ankle rehabilitation at the time of screening.\n3. Acute injury to the musculoskeletal structures of other joints of the lower extremity in the previous 3 months, which impacted joint integrity and function (ie, sprains, fractures) resulting in at least 1 interrupted day of desired physical activity","ALL","18 Years","44 Years",{"count":56,"type":21},80,[24],"This study aims to investigate the effects of various treatments on lumbar and ankle proprioception, balance, and foot function in patients with chronic ankle instability. The objectives include assessing the combined effects of core stability training and intrinsic foot muscle exercises with conventional therapy, the impact of core stability training alone, the effects of intrinsic foot muscle exercises in conjunction with conventional treatment, and the outcomes of conventional therapy alone. Additionally, the study will compare the effectiveness of these different treatment protocols.",[27],"2026-07-23",{"date":62,"type":36},"2026-07-28",{"date":64,"type":36},"2026-05-01",{"date":66,"type":21},"2026-09-01",{"name":68,"class":43},"Cairo University",{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":4,"eligibilityCriteria":75,"healthyVolunteers":11,"sex":52,"minAge":53,"maxAge":76,"enrollmentInfo":77,"targetDuration":4,"studyType":79,"phases":4,"briefSummary":80,"conditions":81,"keywords":84,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":44},"100454389","the-clinical-outcomes-of-the-modified-brostrm-vs-anatomic-reconstruction-operation-in-clai-and-gjl-100454389","NCT05196906","The Clinical Outcomes of the Modified Broström vs Anatomic Reconstruction Operation in CLAI and GJL","The Clinical Outcomes Comparing the Modified Broström vs Anatomic Reconstruction Operation in Chronic Lateral Ankle Instability and Generalized Joint Laxity","Inclusion Criteria:\n\nClinical diagnosis of lateral ankle pain and instability Beighton score ≥4 Age with 18 to 60 years\n\nExclusion Criteria:\n\nPatients with an acute or subacute ankle injury (within 3 months) Injury of the deltoid ligament Alignment of lower extremity greater than 5 degrees Fractures of the lower extremity Stage III or IV osteoarthritis Patients who refused to participate in the study","60 Years",{"count":78,"type":21},100,"OBSERVATIONAL","Investigators designed this prospective cohort study to compare the clinical outcomes of modified Broström operation and anatomical reconstruction for the treatment of CLAI and GJL.",[82,27,83],"Ankle Sprains","Joint Hypermobility",[85,86,87,88,89],"chronic lateral ankle instability","generalized joint laxity","re-injury","modified Brostrom operation","anatomic reconstruction","2025-04-08",{"date":92,"type":36},"2025-04-11",{"date":94,"type":36},"2020-01-01",{"date":96,"type":21},"2025-12-31",{"name":98,"class":43},"Peking University Third Hospital",{"id":100,"slug":101,"hasResults":11,"nctId":102,"briefTitle":103,"officialTitle":104,"acronym":4,"eligibilityCriteria":105,"healthyVolunteers":11,"sex":52,"minAge":53,"maxAge":106,"enrollmentInfo":107,"targetDuration":4,"studyType":22,"phases":109,"briefSummary":110,"conditions":111,"keywords":114,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":128},"100335169","arthroscopic-versus-open-brostrom-for-ankle-instability-100335169","NCT03643926","Arthroscopic Versus Open Brostrom for Ankle Instability","Arthroscopic Versus Open Brostrom for Ankle Instability: a Randomized Clinical Trial","Inclusion Criteria:\n\n* Individuals must be older than 18 and younger than 65 years of age, both genders;\n* Participants must be experiencing instability symptoms at the ankle over the last six months;\n* Clinical diagnosis of ankle instability, defined as the presence of at least one previous ankle sprain associated with a current instability sensation by the patient and the presence of a positive anterior drawer test; the previous lateral ligament injury must be confirmed by Magnetic Resonance Imaging (MRI) findings.\n\nExclusion Criteria:\n\n* Previous surgery involving the affected foot or ankle;\n* History or documented evidence of autoimmune or peripheral vascular diseases;\n* History or documented evidence of peripheral neuropathy (nervous compression syndrome, tarsal tunnel syndrome) or systemic inflammatory disease a (rheumatoid arthritis, spondylitis, Reiter Syndrome, etc.);\n* Associated injuries, such as osteochondral lesions, tendon ruptures and fractures.\n* Associated instability, such as syndesmotic and medial instability.\n* Cavovarus foot;\n* BMI over 35;\n* Previous infiltration in the ankle over the six months preceding the initial assessment;\n* Pregnancy;\n* Any condition that represents a contraindication of the proposed therapies;\n* Impossibility or incapacity to sign the informed Consent Form;\n* History or documented evidence of blood coagulation disorders (including treatment with anti-coagulants, but excluding aspirin);\n* Use of heart pacemaker;\n* Presence of infectious process (superficial on skin and cellular tissue, or deep in the bone) in the region to be treated;","65 Years",{"count":108,"type":21},98,[24],"Background: Ankle sprains are among the most prevalent lesions in primary care. A substantial number of these ligament lesions will develop ankle instability and require a surgical procedure. The Brostrom-Gould technique is the standard surgical approach for this condition, providing excellent results over the years. Thru the last decades, the arthroscopic Brostrom has gain popularity and support by several studies. Yet, there is no consensus regarding the best procedure to treat ankle instability nowadays.\n\nHypothesis: The arthroscopic Brostrom technique will present better levels of pain and function when compared to the standard open approach.\n\nDesign: blinded, in parallel groups, multicentric, randomized, clinical trial.\n\nMaterials and Methods: 98 patients with a diagnosis of chronic ankle instability, referred from primary or secondary health care services, will be assessed and enrolled in this study. Participants will be divided in two groups (randomized by sequentially numbered identical envelopes, which will be administered serially to participants), one containing the open Brostrom repair technique and the other comprehending the arthroscopic Brostrom approach. The assessments will occur in 3, 6, 12, 24 and 48 weeks. Patients will be evaluated primarily by complications and secondarily the Cumberland Ankle Instability Tool (CAIT), American Orthopedic Foot and Ankle Society (AOFAS), the Visual Analogue Scale (VAS), the Foot Function Index (FFI) and the 36 Item Short Form Health Survey (SF-36). The investigators will use Comparison of Two Proportions via relative frequency analysis, the Pearson Correlation the Chi-Square test and the ANOVA for statistical analyses.\n\nDiscussion: This study intends to establish if the arthroscopic Brostrom technique can produce excellent and reliable results when treating chronic ankle instability. A shorter surgical time, a better cosmetic appearance and a smaller soft tissue injury would support the choice for this procedure if the outcomes could be compared to the open approach.",[82,27,112,113],"Ligament Injury","Surgery",[115,31,116,117,118],"ankle","brostrom","open","arthroscopic","2024-09-26",{"date":121,"type":36},"2024-09-27",{"date":123,"type":36},"2019-06-01",{"date":125,"type":21},"2027-12-05",{"name":127,"class":43},"Federal University of São Paulo",2]