[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"intensive-care-unit-icu-admission\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:intensive-care-unit-icu-admission":24},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,46,75,105,130],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":21,"conditions":22,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100651960","supply-induced-demand-in-intensive-care-unit-a-retrospective-trial-100651960",false,"NCT07768410","Supply Induced Demand in Intensive Care Unit: a Retrospective Trial","Inclusion Criteria:\n\n* Patients admitted to the ICU from November 2018 to November 2025\n\nExclusion Criteria:\n\n* Incomplete documentation","ALL","18 Years",{"count":18,"type":19},1500,"ESTIMATED","OBSERVATIONAL","Intensive Care Unit (ICU) represents a high-level healthcare and expensive resource in hospitals. The causes of hospitalization in critical care are therefore multiple, and over the years numerous prognostic scores have been proposed, which therefore correlate the severity of the pathology with the predicted mortality from a statistical point of view. The function of the scores is also to assist the physician in clinical choices. The two most frequently used prognostic scores in critical care are the Acute Physiology And Chronic Health Evaluation (APACHE) II score and the Simplified Acute Physiology Score (SAPS) II.\n\nThe choice to admit a patient to Intensive Care, therefore, is a clinical, economic and managerial choice. Due to the costs of the ICU beds, as well as to the fact that shortage of beds may have a significant clinical impact on patients, many studies addressed the issue of supply-induced scarcity (SIS), i.e. scarcity due to a lack of supply and not to an excess of demand. On the other side, Health Economics has demonstrated that often an increase in supply can generate an increase in demand, even when this increase is not strictly necessary or appropriate. This phenomenon, called supply-induced demand (SID), to the best of our knowledge, few studies have been conducted in critical care settings; moreover, the correlation between SID and outcomes, specifically mortality, has never been demonstrated.\n\nThe aim of this retrospective, single-center study, therefore, is to investigate the presence of SID, and the consequent effects on mortality outcome, in a multispecialty Postoperative Intensive Care Unit.",[23,24,25,26,27],"Intensive Care (ICU)","Intensive Care Unit (ICU) Admission","Intensive Care Unit Survivors","SID","Health and Social Services",[29,30,31,32,26],"Intensive Care Unit","ICU","Intensive Care Unit Admission","Supply Induced Demand","NOT_YET_RECRUITING","2026-08-14",{"date":36,"type":37},"2026-08-17","ACTUAL",{"date":39,"type":19},"2026-08-20",{"date":41,"type":19},"2026-09-20",{"name":43,"class":44},"Saint Camillus International University of Health Sciences","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":55,"conditions":56,"keywords":60,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":45},"100651475","kinetics-and-prognostic-value-of-neurofilament-light-in-post-cardiac-arrest-a-prospective-multicenter-study-100651475","NCT07760636","Kinetics and Prognostic Value of NeuroFilament Light in Post-cardiac Arrest: A Prospective Multicenter Study","CINEFIL","Inclusion Criteria:\n\n* Patients admitted to the ICU for cardiac arrest,\n* Patients who regained consciousness following in-hospital or out-of-hospital cardiac arrest,\n* Patients in a coma upon arrival in the ICU, defined by a Glasgow Coma Scale (GCS) score \\\u003C8,\n* Patients included in the AfterROSC2 cohort,\n\nExclusion Criteria:\n\n* Terminally ill patients (death expected within 3 hours of admission to the ICU),\n* Minors,\n* Patients under legal guardianship,\n* Pregnant women,\n* Patients not enrolled in a social security program,\n* Prior inclusion in the CINEFIL study,\n* Restriction of active therapies prior to the first NFL biomarker assay,\n* Objection by a family member or trusted person, if present",{"count":54,"type":19},270,"The purpose of this study is to assess the prognostic value of absolute value and kinetic of neurofilament light chain (NFL) collected at different time points (at admission, 12h, 24h, 48h, 72h, 96h, and day 7 after ICU admission) in predicting poor and good neurological outcome in comatose patients after cardiac arrest.",[57,24,58,59],"Cardiac Arrest (CA)","Return of Spontaneous Circulation","Comatose",[61,62,63,64,65],"Cardiac arrest","Coma","Neuroprognostication","Biomarkers","Neurofilament light chain","2026-08-10",{"date":68,"type":37},"2026-08-12",{"date":70,"type":19},"2026-09",{"date":72,"type":19},"2028-06",{"name":74,"class":44},"Assistance Publique - Hôpitaux de Paris",{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":81,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":83,"targetDuration":4,"studyType":85,"phases":86,"briefSummary":88,"conditions":89,"keywords":90,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":104},"100629984","biomarker-signature-supported-antibiotic-treatment-decisions-in-icu-100629984","NCT07481773","Biomarker Signature-Supported Antibiotic Treatment Decisions in ICU","Biomarker Signature-Supported Antibiotic Treatment Decisions in Intensive Care Units","BAST-ICU","Inclusion Criteria:\n\n* Admitted to the Intensive Care Unit (ICU)\n* Started on antibiotics for any suspected or confirmed infection in the preceding 72 hours (about 3 days)\n* Treating doctor(s) willing to consider BV test result in antibiotic treatment decision making\n\nExclusion Criteria:\n\n* Severe immunocompromise\u002Fimmunosuppression\n\n  1. Congenital immunodeficiency\n  2. HIV with CD4 \\\u003C 20\n  3. Active chemotherapy and profound neutropenia (ANC \\\u003C 100) expected to last \\> 7 days;\n  4. solid organ or stem cell transplant within preceding 6 months AND active GVHD\n  5. Receiving high dose steroids (Pred \\> 20mg\u002Fday for \\> or = 2 weeks)\n* Advanced metastatic cancer irrespective of treatment\n* Palliative intent, death imminent and inevitable within 4 weeks\n* Antibiotic to be discontinued within 24h (ex. Prophylaxis)\n* Active infection diagnosed and treated with antibiotics within preceding 2 weeks\n* Previously included during the same hospitalization",{"count":84,"type":19},1200,"INTERVENTIONAL",[87],"NA","The goal of this randomized clinical trial is to determine whether a biomarker-signature (BV) supported antibiotic treatment decision matrix can have a beneficial impact on antibiotic use and patient outcomes in an ICU population.",[24],[91,92,93],"ICU, Antibiotic Assesment, Diagnostic, Intervention, Medical Device","Antimicrobial Stewardship","Antimicrobial Resistance","RECRUITING","2026-03-14",{"date":97,"type":37},"2026-03-19",{"date":99,"type":37},"2025-05-13",{"date":101,"type":19},"2028-08",{"name":103,"class":44},"McGill University Health Centre\u002FResearch Institute of the McGill University Health Centre",4,{"id":106,"slug":107,"hasResults":11,"nctId":108,"briefTitle":109,"officialTitle":110,"acronym":4,"eligibilityCriteria":111,"healthyVolunteers":112,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":113,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":115,"conditions":116,"keywords":119,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":122,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":4},"100626458","impact-of-information-and-participation-on-decision-time-for-tracheostomy-or-peg-in-icu-families-100626458","NCT07435896","Impact of Information and Participation on Decision Time for Tracheostomy or PEG in ICU Families","Impact of Information and Participation Strategies on Decision Time for Tracheostomy or PEG Among Family Members of Intensive Care Patients","Inclusion Criteria:\n\n* First-degree relative of an ICU patient with an indication for tracheostomy and\u002For percutaneous endoscopic gastrostomy (PEG)\n* Age ≥ 18 years\n* Able to understand and communicate in Turkish\n* Provides written informed consent\n* Responsible for or involved in the medical decision-making process\n\nExclusion Criteria:\n\n* Cognitive impairment or psychiatric condition interfering with questionnaire completion\n* Refusal to participate\n* Prior participation in this study\n* Inability to complete study questionnaires",true,{"count":114,"type":19},60,"Decisions regarding tracheostomy and percutaneous endoscopic gastrostomy (PEG) in the intensive care unit (ICU) are frequently associated with substantial uncertainty, decisional conflict, and psychosocial burden among patients' relatives. Inadequate or non-tailored information may negatively influence anxiety levels, decision satisfaction, and subsequent adaptation to care responsibilities. Differences in communication patterns and educational background may further affect how families perceive the risks, benefits, and long-term implications of these procedures.\n\nThis prospective study aims to evaluate the impact of relatives' educational level and different information delivery methods on anxiety, decision satisfaction, and the overall decision-making process related to tracheostomy and PEG in the ICU setting. The findings are expected to contribute to the development of structured, education-level-tailored information strategies to improve shared decision-making and family-centered care in critical care practice.",[24,117,118],"Tracheostomy","Percutaneous Endoscopic Gastrostomy (PEG)",[120,117,29],"Percutaneous Endoscopic Gastrostomy","2026-02-21",{"date":123,"type":37},"2026-02-27",{"date":125,"type":19},"2026-03-15",{"date":127,"type":19},"2026-06-15",{"name":129,"class":44},"Elazıg Fethi Sekin Sehir Hastanesi",{"id":131,"slug":132,"hasResults":11,"nctId":133,"briefTitle":134,"officialTitle":135,"acronym":4,"eligibilityCriteria":136,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":137,"targetDuration":4,"studyType":85,"phases":139,"briefSummary":140,"conditions":141,"keywords":145,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":152,"lastUpdatePostDateStruct":153,"startDateStruct":155,"completionDateStruct":157,"leadSponsor":159,"locationsCount":45},"100606520","the-pre-vail-study-100606520","NCT07176624","The PRE-VAIL Study","The Effect of Reducing Enteral Nutrition Before Prone Positioning on Clinical Outcomes in Mechanically Ventilated ARDS Patients: A Multicenter Randomized Controlled Trial (The PRE-VAIL Study)","Inclusion Criteria:\n\n* Age ≥18 years old\n* Within 24 hours of admission to the ICU, one or more organ systems have failed (the Sequential Organ Failure Assessment (SOFA) score of any single organ system is ≥2)\n* Meet the diagnostic criteria for moderate\u002Fsevere ARDS (even after optimizing the ventilation Settings, the oxygenation index is still \\\u003C 150mmHg and PEEP is still ≥5 cm H2O)\n* It is expected to stay in the ICU for more than 48 hours\n\nExclusion Criteria:\n\n* There are contraindications for the prone position\n* There are contraindications for EN, preventing the initiation of early EN (≤48 hours)\n* Expected to die within 48 hours\n* Pregnancy",{"count":138,"type":19},259,[87],"During the prone position, there may be an increase in intragastric pressure. The investigators focus on a scientific question: Whether reducing enteral nutrition before the prone position will benefit patients with severe mechanically ventilated acute respiratory distress syndrome (ARDS).\n\nThe experimental group had the enteral nutrition dose reduced before the prone position, while the control group did not have the enteral nutrition dose reduced",[142,143,144,24],"ARDS (Moderate or Severe)","Prone Position","Enteral Nutrition Feeding",[146,147,148,149,150,151],"ARDS","Mechanical ventilation","Prone position","Enteral nutrition","Gastric retention","Clinical outcome","2026-02-05",{"date":154,"type":37},"2026-02-09",{"date":156,"type":37},"2025-09-14",{"date":158,"type":19},"2028-02-20",{"name":160,"class":44},"The First Hospital of Jilin University"]