[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"interoceptive-awareness\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:interoceptive-awareness":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100648215","interoception-and-symptom-perception-in-acute-copd-exacerbation-100648215",false,"NCT07719231","Interoception and Symptom Perception in Acute COPD Exacerbation","Investigation of the Relationship Between Interoception, Disease Severity, Perception of Dyspnea, Depression, and Sleep Quality in Hospitalized Patients With Acute COPD Exacerbation","Inclusion Criteria:\n\n* Physician-confirmed diagnosis of acute exacerbation of COPD with hospitalization\n* Age 40 years or older\n* Conscious and able to communicate\n* Willing to participate and provide written informed consent\n\nExclusion Criteria:\n\n* Presence of delirium or severe cognitive impairment\n* Requirement for invasive mechanical ventilation\n* Clinical instability preventing safe administration of assessment tools\n* History of severe neurological or psychiatric disorders\n* Any history of malignancy\n* Presence of pneumonia\n* History of stroke","ALL","40 Years","75 Years",{"count":20,"type":21},50,"ESTIMATED","1 Day","OBSERVATIONAL","Interoception refers to the process of perceiving and interpreting internal physiological signals and plays a central role in symptom perception. In conditions with a high symptom burden such as chronic obstructive pulmonary disease (COPD), clinical features including dyspnea perception, depression, and sleep quality may be influenced not only by disease severity but also by the interpretation of internal bodily signals.\n\nRecent evidence suggests that respiratory-related internal signals are transmitted to the central nervous system through multiple afferent pathways and integrated within cortical and subcortical networks, contributing to subjective experiences such as dyspnea. In this context, dyspnea perception may arise from the interaction between disease severity and interoceptive processes.\n\nDepressive symptoms and impaired sleep quality are also closely associated with interoceptive processes and may contribute to the perception of respiratory symptoms. However, studies simultaneously examining interoception, disease severity, dyspnea perception, depression, and sleep quality in hospitalized patients with acute COPD exacerbation are limited.\n\nThis prospective, observational, cross-sectional study will include 50 individuals aged 40 years and older who are hospitalized with acute COPD exacerbation in a Chest Diseases clinic. Data will be collected at a single time point when patients are clinically stable, without interfering with routine clinical care. Participants will be recruited using a consecutive sampling method.\n\nSociodemographic and clinical data will be obtained from patient records and a structured data collection form. Disease severity will be assessed using oxygen requirement, respiratory rate, oxygen saturation, and arterial blood gas values when available. Interoception will be evaluated using the Multidimensional Assessment of Interoceptive Awareness (MAIA-2). Symptom burden will be assessed with the COPD Assessment Test (CAT), dyspnea with the Modified Medical Research Council (mMRC) scale, sleep quality with the Richards-Campbell Sleep Questionnaire (RCSQ), and depressive symptoms with the Hospital Anxiety and Depression Scale - Depression subscale (HADS-D).\n\nStatistical analyses will be performed using IBM SPSS Statistics software. Relationships between variables will be analyzed using Pearson or Spearman correlation depending on data distribution, with a significance level of p\\\u003C0.05.",[26,27],"Acute Exacerbation of Chronic Obstructive Pulmonary Disease","Interoceptive Awareness",[29,27,30,31],"Acute Exacerbation of COPD","Dyspnea Perception","Sleep Quality","NOT_YET_RECRUITING","2026-07-17",{"date":35,"type":36},"2026-07-22","ACTUAL",{"date":38,"type":21},"2026-07-20",{"date":40,"type":21},"2026-08-25",{"name":42,"class":43},"Saglik Bilimleri Universitesi","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":56,"phases":57,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":4},"100638167","adapted-mindfulness-training-for-diabetic-patients-with-impaired-hypoglycemia-awareness-100638167","NCT07586527","Adapted Mindfulness Training for Diabetic Patients With Impaired Hypoglycemia Awareness","Impact of Adapted Mindfulness Training Integrating Interoception on Diabetic Patients With Impaired Awareness of Hypoglycemia: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Diagnosed with type 1 or type 2 diabetes mellitus according to the latest American Diabetes Association (ADA) Standards of Care in Diabetes;\n* Receiving insulin therapy for ≥ 1 year;\n* Age between 18 and 80 years (inclusive);\n* Duration of diabetes ≥ 5 years;\n* Gold score ≥ 4 and Clarke score ≥ 4;\n* Voluntary participation and provision of signed informed consent.\n\nExclusion Criteria:\n\n* Prior experience with mindfulness interventions;\n* Diagnosed with cognitive impairment, psychiatric disorders, or other severe physical comorbidities;\n* Current use of psychotropic medications;\n* Pregnant or lactating women, or women of childbearing potential not using effective contraception.","18 Years","80 Years",{"count":55,"type":21},100,"INTERVENTIONAL",[58],"NA","The purpose of this randomized controlled trial is to evaluate the effectiveness of an 8-week interoception-integrated adapted mindfulness training program for patients with type 1 or type 2 diabetes who experience impaired awareness of hypoglycemia (IAH). The study aims to determine whether this mindfulness intervention, which includes techniques such as body scanning and mindful eating, can help patients better recognize early physiological signals of low blood sugar compared to routine care. Researchers will measure changes in participants' interoceptive awareness and the severity of their IAH over a 3-month follow-up period. The ultimate goal is to provide a practical psychological approach to improve symptom perception and reduce the risk of severe hypoglycemic events in diabetic patients.",[61,27,62],"Impaired Awareness of Hypoglycemia","Mindfulness-based Intervention","2026-05-08",{"date":65,"type":36},"2026-05-14",{"date":67,"type":21},"2026-06-01",{"date":69,"type":21},"2027-06-01",{"name":71,"class":43},"Yangzhou University"]