[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"interscalene-block\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:interscalene-block":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,48,74,103,125,154],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100649786","anterior-suprascapular-and-axillary-vs-interscalene-block-for-analgesia-and-diaphragmatic-function-in-shoulder-surgery-100649786",false,"NCT07739303","Anterior Suprascapular and Axillary vs. Interscalene Block for Analgesia and Diaphragmatic Function in Shoulder Surgery","Comparison of Anterior Suprascapular and Axillary Nerve Block Versus Interscalene Block for Postoperative Analgesia and Diaphragmatic Function in Shoulder Surgery: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients aged between 18 and 65 years\n* American Society of Anesthesiologists (ASA) physical status I, II, or III\n* Patients scheduled to undergo elective arthroscopic shoulder surgery\n* BMI between 18 and 30 kg\u002Fm2\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Known allergy or hypersensitivity to local anesthetics\n* Presence of localized infection at the planned injection site\n* Severe coagulopathy or active use of anticoagulant medications\n* Contralateral phrenic nerve palsy or a diagnosis of severe chronic obstructive pulmonary disease (COPD)\n* History of chronic opioid consumption or neuropathic pain","ALL","18 Years","65 Years",{"count":20,"type":21},70,"ESTIMATED","INTERVENTIONAL",[24],"NA","Shoulder surgeries are among the most frequently performed orthopedic interventions and are often associated with moderate to severe postoperative pain. In these procedures, effective pain management is crucial for early rehabilitation and patient comfort.\n\nPeripheral nerve blockade is widely used for postoperative analgesia in shoulder surgery. While the interscalene brachial plexus block is considered the gold standard for pain control, it is frequently associated with unintended phrenic nerve blockade, leading to hemidiaphragmatic paresis. To minimize respiratory complications while maintaining effective analgesia, alternative diaphragm-sparing regional anesthesia techniques, such as the combination of suprascapular and axillary nerve blocks, have been introduced.\n\nThe aim of this study is to compare the analgesic efficacy and respiratory functions preservation of the ultrasound-guided anterior approach suprascapular combined with axillary nerve block versus interscalene block in patients undergoing shoulder surgery",[27,28,29,30,31],"Peripheral Nerve Block","Pain Management","Diaphragm Protective Block","Upper Extremity","Interscalene Block",[33,31,34,35,28],"Shoulder Arthroscopy","Anterior Suprascapular Block","Axillary Block","RECRUITING","2026-08-06",{"date":39,"type":40},"2026-08-07","ACTUAL",{"date":37,"type":40},{"date":43,"type":21},"2026-12-28",{"name":45,"class":46},"Ankara Etlik City Hospital","OTHER_GOV",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":63,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":69,"leadSponsor":71,"locationsCount":47},"100642380","the-effect-of-intravenous-dexketoprofen-on-the-severity-and-incidence-of-rebound-pain-100642380","NCT07642674","The Effect of Intravenous Dexketoprofen on the Severity and Incidence of Rebound Pain","Evaluation of the Effect of Intravenous Dexketoprofen on the Severity and Incidence of Rebound Pain in Patients Undergoing Interscalene Brachial Plexus Block","Inclusion Criteria:\n\nAge 18-70 years ASA score of I-III Arthroscopic shoulder surgery\n\nExclusion Criteria:\n\nPatients who do not wish to participate in the study Creatinine clearance \\\u003C50 mL\u002F min Patients for whom NSAID use is contraindicated due to heart failure, Patients with psychiatric or cognitive dysfunction that would impair their ability to assess visual analog scale (VAS) pain scores Patients for whom peripheral nerve block is contraindicated","70 Years",{"count":57,"type":21},66,[24],"Orthopedic shoulder surgeries are associated with severe postoperative pain, particularly within the first 24-48 hours after surgery. In postoperative pain management, single or continue interscalene brachial plexus blocks, acetaminophen, nonsteroidal anti-inflammatory drugs (NSAIDs), and opioids administered as needed are commonly used as components of multimodal analgesia.\n\nRebound pain is defined as severe postoperative pain (VAS ≥ 7) occurring within the first 24 hours after resolution of the block. It is considered an adverse effect of regional anesthesia and typically develops 8-12 hours after a single-shot nerve block. Risk factors for rebound pain include pre-existing pain, female sex, younger age, bone surgery, lack of intraoperative dexamethasone administration, and inadequate analgesia.\n\nThe primary objective of this study is to evaluate the effect of intravenous dexketoprofen administered during the postoperative period on the incidence and severity of rebound pain in patients undergoing shoulder surgery with interscalene brachial plexus block",[61,28,62,31],"Postoperative Pain","Rebound Pain",[64],"Rebaund pain, Interscalene block, postoperative pain","2026-06-11",{"date":67,"type":40},"2026-06-12",{"date":65,"type":40},{"date":70,"type":21},"2027-01-01",{"name":72,"class":73},"Eskisehir Osmangazi University","OTHER",{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":81,"targetDuration":4,"studyType":22,"phases":82,"briefSummary":83,"conditions":84,"keywords":88,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":47},"100623570","comparison-of-the-effects-of-regional-anesthesia-on-brain-and-carotid-artery-oxygenation-in-shoulder-surgery-100623570","NCT07398352","Comparison Of The Effects Of Regional Anesthesia On Brain And Carotid Artery Oxygenation In Shoulder Surgery","Comparison Of The Effect Of Interscalene Block Alone And The Combination Of Interscalene Block And Superficial Cervical Block On Brain Oxygenation And Carotid Artery Diameter In Shoulder Surgery","Inclusion Criteria:\n\n* 18-65 years patient\n* American Society of Anesthesiologists (ASA) I-II patient\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years or \\> 65 years\n* History of carotid endarterectomy\n* History of cerebrovascular accident(CVA)\n* Body Mass index (BMI)\\>35 kg\u002Fm²\n* Inability to cooperate or comply with study procedures\n* Liver and kidney failure\n* Pregnancy and breastfeeding\n* ASA pyhsical status III-V\n* Contraindication to regional anesthesia",{"count":20,"type":21},[24],"The aim of our study was to compare the effects of interscalene block alone and the combination of interscalene block and superficial cervical block on cerebral oxygenation, carotid artery diameter, intraoperative hemodynamics, laboratory parameters, clinical course and postoperative pain in patients undergoing shoulder surgery.",[31,85,86,87],"Superficial Cervical Block","Cerebral Perfusion","Shoulder Surgeries",[89,90,91,92,93],"brain perfusion","carotid artery diameter","interscalene brachial plexus block","superficial cervical plexus block","shoulder surgery","2026-03-23",{"date":96,"type":40},"2026-03-24",{"date":98,"type":40},"2026-02-23",{"date":100,"type":21},"2026-12-15",{"name":102,"class":73},"Sanliurfa Mehmet Akif Inan Education and Research Hospital",{"id":104,"slug":105,"hasResults":11,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":4,"eligibilityCriteria":109,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":110,"targetDuration":4,"studyType":22,"phases":112,"briefSummary":113,"conditions":114,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":117,"lastUpdatePostDateStruct":118,"startDateStruct":120,"completionDateStruct":121,"leadSponsor":123,"locationsCount":47},"100625592","interscalene-block-versus-anterior-suprascapular-block-for-post-thoracotomy-shoulder-pain-100625592","NCT07424638","Interscalene Block Versus Anterior Suprascapular Block for Post-Thoracotomy Shoulder Pain","Interscalene Block Versus Anterior Suprascapular Block for Post-Thoracotomy Shoulder Pain: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age \\> 18 years and ≤ 65 years old.\n* American Society of Anesthesiologists (ASA) physical status II-III.\n* Body mass index 18-35 kg\u002Fm2.\n* Patients who have a confirmed diagnosis of lung cancer and are scheduled for elective open-lung surgery.\n\nExclusion Criteria:\n\n* Allergy to local anesthetics.\n* Known psychiatric or neurologic disorders.\n* Alcohol or narcotics abuse.\n* Contraindications to thoracic epidural or suprascapular block, or interscalene block, e.g., coagulopathy or local infection.\n* Pre-existing shoulder symptoms.\n* History of previous thoracotomy.\n* Severe restrictive or obstructive pulmonary disease.\n* Pre-existing contralateral diaphragmatic paralysis.",{"count":111,"type":21},75,[24],"This study aims to compare the frequency of occurrence of ipsilateral shoulder pain in patients undergoing thoracotomy with ultrasound-guided interscalene block, anterior suprascapular block as adjunct to epidural and epidural block only.",[31,34,115,116],"Thoracotomy","Shoulder Pain","2026-02-21",{"date":119,"type":40},"2026-02-24",{"date":117,"type":40},{"date":122,"type":21},"2026-07-30",{"name":124,"class":73},"National Cancer Institute, Egypt",{"id":126,"slug":127,"hasResults":11,"nctId":128,"briefTitle":129,"officialTitle":129,"acronym":130,"eligibilityCriteria":131,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":132,"targetDuration":4,"studyType":22,"phases":134,"briefSummary":136,"conditions":137,"keywords":139,"overallStatus":144,"whyStopped":4,"lastUpdateSubmitDate":145,"lastUpdatePostDateStruct":146,"startDateStruct":148,"completionDateStruct":150,"leadSponsor":152,"locationsCount":47},"100604220","phase-4-effect-of-local-anesthetic-concentration-on-rebound-pain-a-randomized-control-study-100604220","NCT07146685","Effect of Local Anesthetic Concentration on Rebound Pain: A Randomized Control Study","RPRCT","Inclusion Criteria:\n\n* Total shoulder replacement patients (anatomic and reverse)\n* Adult patients (greater than or equal to 18 years)\n* Any gender\n* Any race\n\nExclusion Criteria:\n\n* \\- Chronic Pain diagnoses including:\n* substance\u002Fopioid use disorder\n* complex regional pain syndromes\n* fibromyalgia\n* Daily persistent opioid use spanning 3 months prior to surgery date\n* Allergy to local anesthetics or NSAIDS\n* Respiratory pathologies including:\n* CPAP- non-compliant \u002F untreated obstructive sleep apnea\n* COPD\n* Restrictive lung disease (pulmonary fibrosis, interstitial pneumonia, etc)\n* Contralateral diaphragm dysfunction\n* BMI \\> 40\n* Ipsilateral extremity pre-existing nerve injury\n* GFR \\\u003C 60\n* NSAID contraindications\n* Inability to follow up\n* Revision surgery\n* Patients requesting block as primary (avoidance of general anesthesia)\n* Need or request for brachial plexus catheter or liposomal bupivacaine\n* Vulnerable populations (pregnancy, incarceration, etc)\n* non-English speaking",{"count":133,"type":21},168,[135],"PHASE4","Randomized control study that compares different concentrations of local anesthetic to investigate whether a lower concentration of local anesthetic would contribute to lower rebound pain scores at 24 hours post op in patients undergoing anatomic or reverse total shoulder arthroplasty.",[62,138,31],"Shoulder Arthroplasty",[140,141,142,143],"local anesthetics","rebound pain","brachial plexus","shoulder arthroscopy","NOT_YET_RECRUITING","2025-08-20",{"date":147,"type":40},"2025-08-28",{"date":149,"type":21},"2026-01-01",{"date":151,"type":21},"2029-01-01",{"name":153,"class":73},"University of Virginia",{"id":155,"slug":156,"hasResults":11,"nctId":157,"briefTitle":158,"officialTitle":159,"acronym":4,"eligibilityCriteria":160,"healthyVolunteers":11,"sex":16,"minAge":161,"maxAge":18,"enrollmentInfo":162,"targetDuration":4,"studyType":22,"phases":164,"briefSummary":165,"conditions":166,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":172,"lastUpdatePostDateStruct":173,"startDateStruct":175,"completionDateStruct":177,"leadSponsor":179,"locationsCount":47},"100599918","ultrasound-guided-interscalene-suprascapular-and-anterior-glenoid-nerve-blocks-on-diaphragmatic-excursion-and-analgesia-following-arthroscopic-shoulder-surgery-100599918","NCT07090733","Ultrasound Guided Interscalene, Suprascapular and Anterior Glenoid Nerve Blocks on Diaphragmatic Excursion and Analgesia Following Arthroscopic Shoulder Surgery","The Effect of Ultrasound Guided Interscalene, Suprascapular and Anterior Glenoid Nerve Blocks on Diaphragmatic Excursion and Analgesia Following Arthroscopic Shoulder Surgery: A Prospective Randomized Controlled Study","Inclusion Criteria:\n\n* Age from 21 to 65 years.\n* Both sexes.\n* American Society of Anesthesiologists (ASA) physical status I or II.\n* Scheduled for arthroscopic shoulder surgery.\n\nExclusion Criteria:\n\n* Patient's refusal to participate.\n* Patients with a history of allergy to local anesthetics.\n* Patients with a history of chronic use of painkillers.\n* Patients presented with mental dysfunction.\n* Patients with coagulation disorders.\n* Patients presented with skin or soft tissue infection at the proposed site of needle Insertion.\n* Pregnant Patients.\n* Patients with Chronic Obstructive Pulmonary Disease (COPD) or a Body Mass Index (BMI) of more than 40.","21 Years",{"count":163,"type":21},80,[24],"This study aims to evaluate the diaphragmatic movement and postoperative analgesia following anterior glenoid, suprascapular, and interscalene nerve blocks in patients undergoing elective arthroscopic shoulder surgery.",[31,167,168,169,170,171],"Suprascapular Nerve Block","Anterior Glenoid Nerve Block","Diaphragmatic Excursion","Analgesia","Arthroscopic Shoulder Surgery","2025-07-21",{"date":174,"type":40},"2025-07-29",{"date":176,"type":40},"2025-01-01",{"date":178,"type":21},"2025-12-31",{"name":180,"class":73},"Tanta University"]