[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"iron-deficiency-anemia-in-pregnancy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:iron-deficiency-anemia-in-pregnancy":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,52],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":4},"100648429","comparing-two-intravenous-iron-treatments-for-anemia-in-kurdish-pregnant-women-100648429",false,"NCT07721519","Comparing Two Intravenous Iron Treatments for Anemia in Kurdish Pregnant Women","Comparison of Clinical Efficacy and Maternal Satisfaction: Intravenous Ferric Carboxymaltose Versus Iron Sucrose for Treatment of Iron Deficiency Anemia in a Sample of Kurdish Pregnant Women: A Multicenter, Randomized, Open-Label Trial With Blinded Outcome Assessment","Inclusion Criteria:\n\n* Parity: All parity levels accepted (Para 0, Para 1, Para 2-4, and Para 5 or more).\n* Pregnancy Stage: Currently in the second or third trimester of pregnancy (greater than 14 weeks gestation).\n* Confirmed Iron Deficiency Anemia (IDA): Documented Hemoglobin (Hb) less than 11 g\u002FdL AND Serum Ferritin less than 30 ng\u002FmL.\n* Medical Indication for Intravenous (IV) Iron: Must meet at least one of the following specific clinical indications:\n\n  1. Intolerance to oral iron therapy (e.g., severe nausea, severe constipation, or gastrointestinal distress).\n  2. Failure to respond to oral iron therapy (defined as a Hemoglobin increase of less than 1 g\u002FdL after 3 weeks of compliant oral intake).\n  3. Late presentation in the third trimester (greater than 34 weeks gestation) requiring rapid correction of anemia.\n  4. Moderate to severe anemia at presentation (defined as Hemoglobin less than 9.0 g\u002FdL).\n\nExclusion Criteria:\n\n* First trimester of pregnancy (less than or equal to 14 weeks gestation).\n* Known hypersensitivity, allergy, or previous severe adverse reaction to intravenous iron formulations or any of their components.\n* Anemia due to causes other than iron deficiency (e.g., vitamin B12 or folate deficiency, hemoglobinopathies, anemia of chronic disease).\n* Active, severe systemic infection.\n* Relevant medical exclusions , such as severe hepatic or renal impairments","FEMALE","18 Years","45 Years",{"count":20,"type":21},400,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to compare two types of intravenous (IV) iron-Ferric Carboxymaltose (FCM) and Iron Sucrose (IS)-to learn which one works better to treat iron deficiency anemia in pregnant women who have a clear medical need for IV iron. It will also learn about the safety of both drugs. The main questions it aims to answer are:\n\n1. Does FCM lead to a higher increase in hemoglobin (blood iron) levels 4 weeks after treatment compared to IS?\n2. What medical problems or side effects do women experience with each drug?\n3. Does FCM reduce the number of hospital visits and improve women satisfaction?\n\nParticipants will:\n\n1. Be in their second or third trimester and share the same precise medical indications requiring IV iron (such as severe anemia, no improvement from pills, or being very late in their pregnancy).\n2. Be randomly assigned from the start to receive either FCM or IS through an IV, with the total dose calculated based on their body weight and blood tests.\n3. Receive FCM in one or more full doses, or receive IS split into multiple smaller sessions up to 3 times a week.\n4. Visit the clinic for their assigned infusions and undergo blood tests and satisfaction surveys twice: right before starting treatment and 1 month after receiving the medication.",[27],"Iron Deficiency Anemia in Pregnancy",[29,30,31,32,33,34,35,36,37,38,39],"Iron Deficiency Anemia","Patient Satisfaction","Serum Ferritin","Randomized Controlled Trial","Ganzoni Formula","Iron Sucrose","Ferric Carboxymaltose","Intravenous Iron Therapy","Maternal Health","Third Trimester Anemia","Second Trimester Anemia","NOT_YET_RECRUITING","2026-07-18",{"date":43,"type":44},"2026-07-23","ACTUAL",{"date":46,"type":21},"2026-09-01",{"date":48,"type":21},"2028-12-01",{"name":50,"class":51},"Hawler Medical University","OTHER",{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":61,"targetDuration":4,"studyType":63,"phases":4,"briefSummary":64,"conditions":65,"keywords":70,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":82},"100583650","maternal-iron-deficiency-and-childhood-health-100583650","NCT06879080","Maternal Iron Deficiency and Childhood Health","Maternal Iron Deficiency and Childhood Health- a Prospective Cohort Study","MATILDA","Inclusion Criteria:\n\n* Pregnant\n* Can read and write Finnish, Swedish or English\n\nExclusion Criteria:\n\n* Illiterate",true,{"count":62,"type":21},6000,"OBSERVATIONAL","The aim of this prospective observational cohort study is to study maternal iron deficiency and iron deficiency anemia and the use of iron supplements in pregnancy and their impact on the health of the offspring and pregnancy outcomes.\n\nAll women coming to Tampere University Hospital for prenatal checkups and\u002For labor are recruited to the study. After giving their consent the mothers fill an online questionnaire about about possible maternal anemia and its diagnosis in pregnancy, iron deficiency and its diagnosis in pregnancy, maternal use of iron supplement or folic acid and it´s timing, about possible other chronic disease and their medications during pregnancy, and whether the mother has got intravenous iron infusions in pregnancy. Mothers also give their permit to use their in-and outpatient data from pregnancy until hospital discharge and to follow the health of their offspring from birth until 7 years of age from in- and outpatient records.We aim to recruit 6000 mother-child-pairs.\n\nThe health of the offspring (growth, diagnoses, medication, possible therapies, need of support at daycare or school) will be followed for the first month, then at 1,5 years, four years and seven years of age from the patient records.\n\nIn addition to the cohort study, two nested cohort studies will be performed. The aim of the nested cohort studies is to study the correlation of maternal iron status to the iron status of the child. Secondary aim is to evaluate iron biomarkers, especially reticulocyte hemoglobin, and their reliability to interpret neonatal iron status.\n\nA 100 mothers with diagnosed iron deficiency and iron supplementation (p.o. or i.v.) in pregnancy, are recruited to Nested cohort 1. For the nested cohort 2, a 100 mothers with diabetes requiring insulin therapy in pregnancy are recruited. Tor these two cohorts, a 100 mothers without iron deficiency or diabetes will be recruited as controls. Iron status of the mother will be tested before delivery from blood sample. The iron status of the offspring will be checked from umbilical blood, at 2 days of age at the same time other lab tests are taken, at eight months and two and five years of age. In addition to the laboratory tests, parents fill up an electronical questionnaire at eight months, two and five years about the nutrition, sleep, behaviour and cognitive and motor skills of their child.\n\nThe researchers try to find out, whether iron deficiency in pregnancy has long-term effects on the health and development of the offspring, and how the iron status correlates between the mother and the child, and does it have impact on their sleep, behaviour or skills.",[66,67,68,27,69],"Iron Deficiency Anaemia in Childbirth","Iron Deficiency","Iron Deficiency in Pregnancy","Iron Status",[71],"iron deficiency, iron deficiency anemia, pregnancy, pregnancy outcomes, health of the offspring","RECRUITING","2025-03-11",{"date":75,"type":44},"2025-03-17",{"date":77,"type":44},"2024-04-22",{"date":79,"type":21},"2034-12-31",{"name":81,"class":51},"Tampere University Hospital",1]