[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"ischemia-reperfusion\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:ischemia-reperfusion":50},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":5},"100658600","check-nirs2d-study-100658600",false,"NCT07854431","CHECK-NIRS2D-Study","Influence of External Physiological and Behavioral Factors on Two-Dimensional Near-Infrared Spectroscopy-Based Imaging in Healthy Volunteers: A Controlled Experimental Study","Inclusion Criteria:\n\n* Healthy volunteers aged 20-40 years\n* Written informed consent\n* Ability to understand and comply with the study procedures\n\nExclusion Criteria:\n\n* Age below 20 years or above 40 years\n* Cardiovascular disease or other relevant medical conditions\n* current medication, where relevant to the study procedures\n* contraindication to or inability to undergo the planned examinations\n* Any condition that may interfere with the study procedures or outcome measurements",true,"ALL","20 Years","40 Years",{"count":21,"type":22},20,"ESTIMATED","OBSERVATIONAL","The study investigates how external, physiological, and behavioral factors influence the measurement of regional tissue oxygenation using two-dimensional near-infrared spectroscopy (NIRS) imaging in healthy volunteers. It aims to improve the standardization and reliability of this non-invasive method for assessing microvascular perfusion and tissue oxygenation.\n\nThe study also examines the effects of temporary vascular occlusion, ambient temperature, physical activity, caffeine consumption, and nicotine consumption on NIRS-based tissue oxygenation measurements. The findings are intended to establish a standardized measurement protocol for future clinical research and the assessment of microvascular perfusion in critically ill patients.",[26,27,28,29,30,31,32,33,34,35,36,37],"NIRS","Tissue Oxygenation","Microvascular Perfusion","Vascular Occlusion Test","Ischemia-reperfusion","Healty Volunteers","Physiological and Behavioral Factors","Temperature","Caffeine","Nicotine","Microcirculation","Protocol Standardization","RECRUITING","2026-09-28",{"date":41,"type":42},"2026-10-02","ACTUAL",{"date":44,"type":42},"2026-07-28",{"date":46,"type":22},"2027-03-01",{"name":48,"class":49},"Heinrich-Heine University, Duesseldorf","OTHER","Ischemia-Reperfusion"]