[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"laparoscopic-inguinal-hernia-repair\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:laparoscopic-inguinal-hernia-repair":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,53],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":29,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100652700","individualized-vs-standard-peep-and-oxygen-reserve-index-in-laparoscopic-hernia-surgery-100652700",false,"NCT07775573","Individualized vs Standard PEEP and Oxygen Reserve Index in Laparoscopic Hernia Surgery","The Effect of Individualized Positive End-Expiratory Pressure Application on Perioperative Oxygenation Assessed by Oxygen Reserve Index Compared to Standard PEEP in Patients Undergoing Laparoscopic Inguinal Hernia Surgery: A Prospective Observational Study","Inclusion Criteria:\n\n* Aged 18-75 years\n* ASA physical status I-III\n* Scheduled for elective laparoscopic unilateral inguinal hernia repair under general anesthesia\n* Body mass index (BMI) \\\u003C 35 kg\u002Fm²\n* Written informed consent obtained\n\nExclusion Criteria:\n\n* Age below 18 or above 75 years\n* ASA physical status IV-V\n* Emergency surgical procedure\n* Severe chronic or restrictive pulmonary disease\n* Pulmonary hypertension\n* Obstructive sleep apnea syndrome\n* Preoperative peripheral oxygen saturation \\\u003C 94% on room air\n* Respiratory tract infection within the last two weeks\n* Severe cardiac failure (NYHA III-IV)\n* Pregnancy\n* Communication difficulties preventing NRS assessment\n* Surgical complications during the procedure\n* Operation duration exceeding 3 hours\n* Refusal to provide informed consent","ALL","18 Years","75 Years",{"count":20,"type":21},60,"ESTIMATED","OBSERVATIONAL","During laparoscopic surgery under general anesthesia, lung function can be affected by increased abdominal pressure and patient positioning. Positive end-expiratory pressure (PEEP) is a ventilator setting that helps keep the lungs open during surgery. In standard practice, a fixed PEEP level is applied to all patients. An individualized PEEP approach tailors this setting to each patient based on lung recruitment maneuvers.\n\nThis study investigates whether individualized PEEP improves oxygenation compared to standard PEEP in patients undergoing laparoscopic inguinal hernia surgery. Oxygenation will be continuously monitored using the Oxygen Reserve Index (ORI), a non-invasive sensor. Lung aeration will also be assessed before and after surgery using bedside lung ultrasound.",[25,26,27,28],"Atelectasis","Perioperative Oxygenation","Laparoscopic Inguinal Hernia Repair","Mechanical Ventilation",[30,31,32,33,34,35,36,37,38,39],"Positive End-Expiratory Pressure","PEEP titration","Oxygen Reserve Index","ORI","Lung Ultrasound","Recruitment Maneuver","Lung Protective Ventilation","Dynamic Compliance","Pneumoperitoneum","Trendelenburg Position","NOT_YET_RECRUITING","2026-08-18",{"date":43,"type":44},"2026-08-20","ACTUAL",{"date":46,"type":21},"2026-09",{"date":48,"type":21},"2027-10",{"name":50,"class":51},"Fatih Sultan Mehmet Training and Research Hospital","OTHER",1,{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":4,"eligibilityCriteria":59,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":60,"enrollmentInfo":61,"targetDuration":4,"studyType":62,"phases":63,"briefSummary":65,"conditions":66,"keywords":71,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":4},"100639163","transversalis-fascia-plane-block-versus-m-tapa-block-after-laparoscopic-inguinal-hernia-repair-100639163","NCT07619053","Transversalis Fascia Plane Block Versus M-TAPA Block After Laparoscopic Inguinal Hernia Repair","Transversalis Fascia Plane Block Versus Modified Thoracoabdominal Nerve Block Through Perichondrial Approach (M-TAPA) for Postoperative Analgesia After Laparoscopic Inguinal Hernia Repair: A Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients aged 18-65 years\n* ASA physical status I-III\n* Scheduled for elective laparoscopic inguinal hernia repair\n* Body mass index (BMI) 18-35 kg\u002Fm²\n* Ability to understand and use the patient-controlled analgesia (PCA) device\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Refusal to participate\n* Allergy to local anesthetics\n* Infection at the injection site\n* Coagulopathy or ongoing anticoagulant therapy\n* Chronic opioid use or opioid dependence\n* Severe hepatic or renal insufficiency\n* Pregnancy or breastfeeding\n* Cognitive impairment or inability to communicate pain scores\n* Body mass index (BMI) \\>35 kg\u002Fm²","65 Years",{"count":20,"type":21},"INTERVENTIONAL",[64],"NA","This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Transversalis Fascia Plane Block (TFPB) and the Modified Thoracoabdominal Nerve Block through Perichondrial Approach (M-TAPA) in patients undergoing laparoscopic inguinal hernia repair. The primary outcome is the Visual Analog Scale (VAS) score within the first 24 hours after surgery. Secondary outcomes include total opioid consumption, requirement for rescue analgesia, block-related complications and adverse effects (hematoma, local anesthetic systemic complications, vascular puncture, and infection), patient satisfaction assessed using a Likert scale, quality of recovery assessed using the QoR-15 questionnaire, and incidence of postoperative nausea and vomiting.",[67,68,69,70,27],"Transversalis Fascia Plane Block","Mtapa Block","Regional Anaesthesia","Postoperative Pain",[72,73,74,75],"TFPB","M-TAPA","İNGUİNAL HERNİA","TRANSVERSALİS FASCİA PLANE BLOCK","2026-05-26",{"date":78,"type":44},"2026-06-01",{"date":80,"type":21},"2026-11-30",{"date":82,"type":21},"2027-07-30",{"name":84,"class":51},"Antalya City Hospital"]