[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"lead-burdened-type-2-diabetic-nephropathy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:lead-burdened-type-2-diabetic-nephropathy":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":4},"100647287","intravenous-chelators-in-lead-burdened-type-2-diabetic-nephropathy-100647287",false,"NCT07706946","Intravenous Chelators in Lead-Burdened Type 2 Diabetic Nephropathy","A Prospective Study on Intravenous Chelator Therapy for Slowing Renal Function Progression in Patients With Type 2 Diabetic Nephropathy Combined With Lead Burden","Inclusion Criteria:\n\n* 1\\. Diagnosed with type 2 diabetic nephropathy; 2. Baseline blood lead level ≥5 µg\u002Fdl; 3. Chronic kidney disease stage ≤3; 4. 24-hour urinary protein \\\u003C 8 g; 5. Age ≥18 years old; 6. Able to provide written informed consent.\n\nExclusion Criteria:\n\n* 1\\. Combined hypertension; 2. Combined hyperlipidemia; 3. History of autoimmune diseases; 4. Personal history of malignant tumors; 5. Reversible renal insufficiency (malignant hypertension, urinary tract infection, recent use of nephrotoxic drugs); 6. Past occupational lead exposure history; 7. Drug allergy to calcium disodium edetate; 8. Unable to complete follow-up or provide informed consent.","ALL","18 Years",{"count":19,"type":20},42,"ESTIMATED","INTERVENTIONAL",[23],"NA","Based on previous basic experiments revealing that patients with type 2 diabetic nephropathy exhibit higher blood lead levels than the general population, this study aims to systematically evaluate the impacts of short-term and long-term blood lead exposure on renal function progression in such patients, so as to provide novel epidemiological evidence for clinical intervention.",[26],"Lead-Burdened Type 2 Diabetic Nephropathy","NOT_YET_RECRUITING","2026-07-12",{"date":30,"type":31},"2026-07-16","ACTUAL",{"date":33,"type":20},"2026-08-01",{"date":35,"type":20},"2029-01-01",{"name":37,"class":38},"The Fourth Affiliated Hospital of Zhejiang University School of Medicine","OTHER"]