[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"loneliness\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:loneliness":28},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,56,0,25,[9,49,77,104,144,169,196,218,258,288,319,352,372,395,423,448,471,500,525,551,570,592,618,643,682],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100630506","engage-coaching-r33-phase-100630506",false,"NCT07488559","Engage Coaching (R33 Phase)","Engage Coaching to Reduce Social Isolation and Loneliness to Prevent Suicide in Later Life","Inclusion criteria:\n\n* Age 60 or older\n* Access to social activities outside the home, including through living in senior living communities\n* Clinically-significant loneliness over the prior month.\n\nExclusion criteria:\n\n* Current problem drinking\n* Psychosis\n* Significant cognitive impairment\n* Hearing problems that preclude engagement with S-ENG and research assessors.","ALL","60 Years",{"count":20,"type":21},120,"ESTIMATED","INTERVENTIONAL",[24],"NA","The purpose of this study is to test whether an individual coaching program helps adults age 60 and older feel more connected to other people in ways that matter to them.",[27,28,29,30],"Social Connection","Loneliness","Suicide Ideation","Social-emotional Quality of Life",[28,32,33,34,35],"Older adults","Ecological momentary assessment","Engage Psychotherapy","Late-life suicide","RECRUITING","2026-08-13",{"date":39,"type":40},"2026-08-17","ACTUAL",{"date":42,"type":40},"2026-06-30",{"date":44,"type":21},"2028-12-31",{"name":46,"class":47},"University of Rochester","OTHER",1,{"id":50,"slug":51,"hasResults":12,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":57,"sex":17,"minAge":58,"maxAge":4,"enrollmentInfo":59,"targetDuration":4,"studyType":22,"phases":61,"briefSummary":62,"conditions":63,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":76},"100642586","using-virtual-reality-travel-to-reduce-loneliness-in-older-adults-100642586","NCT07644416","Using Virtual Reality Travel to Reduce Loneliness in Older Adults","Virtual Reality Travel (VRT) as a Loneliness Intervention for Older Adults: A Pilot Randomized Controlled Trial","VRT","Inclusion Criteria:\n\n* Adults aged 65 years or older\n* Express willingness to engage with VR technology\n\nExclusion Criteria:\n\n\\- No self-reported physical, sensory, neurological, or cognitive conditions that would make VR use unsafe or impractical (e.g., uncontrolled seizures, severe vertigo, or significant uncorrected vision\u002Fhearing impairments).",true,"65 Years",{"count":60,"type":21},40,[24],"This study aims to investigate whether and how virtual reality travel (VRT) can reduce loneliness among older adults. It will utilize a mixed-methods research design that combines an randomly assigned experiment with follow-up semi-structured interviews.\n\nThis is a pilot study and it is essential to establish the feasibility and acceptability of the protocol, assess the tolerability of VR technology in this population prior to conducting a full-scale RCT, and generate preliminary effect size estimates to inform future sample size calculations.",[28,64,65,66],"Older Adults (65 Years and Older)","Virtual Reality","Leisure Activities","2026-08-12",{"date":69,"type":40},"2026-08-14",{"date":71,"type":40},"2026-06-01",{"date":73,"type":21},"2027-05-30",{"name":75,"class":47},"Indiana University",3,{"id":78,"slug":79,"hasResults":12,"nctId":80,"briefTitle":81,"officialTitle":81,"acronym":82,"eligibilityCriteria":83,"healthyVolunteers":57,"sex":17,"minAge":84,"maxAge":85,"enrollmentInfo":86,"targetDuration":4,"studyType":22,"phases":88,"briefSummary":89,"conditions":90,"keywords":91,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":48},"100610093","sauna-for-offline-connections-and-interactive-authentic-living-100610093","NCT07223099","Sauna for Offline Connections and Interactive, Authentic Living","SOCIAL","Inclusion Criteria:\n\n* Aged 19-25\n* English-speaking\n* Able to provide written informed consent\n* Graduated from high school or high school equivalent\n* Elevated level of loneliness\n* Able and willing to receive study text messages\n* Able to attend weekly in-person sauna visits in San Francisco, CA\n\nExclusion Criteria:\n\n* Self-reported heat intolerance\n* Pregnancy, active lactation, or intention to become pregnant during the study period\n* Regular use of any nicotine products, including cigarettes, vapes, chewing tobacco, or other forms of nicotine (if use is not regular, must be willing to refrain for 24 hours before and 24 hours after sauna visits)\n* Current social heat practices 2 or more times per month (e.g., visiting sauna or hot tub facilities with others present)\n* Unwilling to refrain from using marijuana products and alcohol for the 24 hours before and 24 hours after sauna visits\n* Unwilling to refrain from heavy exercise on the day of sauna visits\n* Any medical condition that, in the opinion of investigators, may increase the risk of sauna use or introduce excessive variance into physiological or behavioral responses to sauna visits\n* Use of any medication that might impact thermoregulatory capacity or that, in the opinion of investigators, would increase risk of study participation or introduce excessive variance into physiological or behavioral responses to sauna visits","19 Years","25 Years",{"count":87,"type":21},15,[24],"This pilot trial will test an intervention (sauna visits) targeting reductions in loneliness in adults aged 19-25 years.\n\nParticipants will:\n\n* Visit a sauna in San Francisco once per week for 2 hours by themselves or with a friend, for 8 weeks total\n* Complete online surveys throughout their participation\n\nThe main question this pilot trial aims to answer are:\n\n* To what extent do participants find the study design acceptable?\n* To what extent do participants complete the weekly sauna visits?\n* To what extent do participants complete the weekly online surveys?",[28],[28,92,93,94,95],"Sauna","Gen Z","Young adult","Emerging adult","2026-08-11",{"date":37,"type":40},{"date":99,"type":40},"2026-04-20",{"date":101,"type":21},"2027-03-30",{"name":103,"class":47},"University of California, San Francisco",{"id":105,"slug":106,"hasResults":12,"nctId":107,"briefTitle":108,"officialTitle":109,"acronym":4,"eligibilityCriteria":110,"healthyVolunteers":57,"sex":17,"minAge":111,"maxAge":112,"enrollmentInfo":113,"targetDuration":4,"studyType":22,"phases":115,"briefSummary":116,"conditions":117,"keywords":123,"overallStatus":134,"whyStopped":4,"lastUpdateSubmitDate":135,"lastUpdatePostDateStruct":136,"startDateStruct":138,"completionDateStruct":140,"leadSponsor":142,"locationsCount":48},"100650926","latin-dance-and-psychological-health-in-primary-school-children-100650926","NCT07755995","Latin Dance and Psychological Health in Primary School Children","Effects of Latin Dance Intervention on Psychologic Health, Loneliness, Enjoyment and Well-being Among Primary School Children in Gansu, China","Inclusion Criteria:\n\n* Primary school children aged 6-12 years.\n* Currently enrolled in a participating primary school in Gansu, China.\n* Able to participate safely in school-based physical activities and Latin dance sessions.\n* Able to understand and complete the study questionnaires.\n* Willing to participate in the 12-week intervention and study assessments.\n* Written informed consent provided by a parent or legal guardian.\n* Assent provided by the child.\n\nExclusion Criteria：\n\n* A medical condition, physical disability, or musculoskeletal injury that would make participation in physical activity or Latin dance unsafe.\n* A health condition for which a physician or school health professional advises against participation in moderate-intensity physical activity.\n* Current participation in regular Latin dance training or another structured dance intervention.\n* Participation in another psychological or physical activity intervention that may affect the study outcomes.\n* Inability to participate regularly in the intervention sessions or complete the study assessments.","6 Years","12 Years",{"count":114,"type":21},60,[24],"This study aims to examine the effects of a 12-week Latin dance intervention on loneliness, anxiety, depression, perceived stress, physical activity enjoyment, and well-being among primary school children in Gansu, China. Eligible participants will be randomly assigned to either a Latin dance intervention group or a control group. The intervention group will participate in two supervised Latin dance sessions per week, including Rumba, Cha-cha, and Jive, while the control group will participate in regular physical education activities. The outcomes will be assessed before and after the 12-week intervention using validated questionnaires. The findings may provide evidence regarding the effectiveness of school-based Latin dance as a strategy for promoting children's psychological health and well-being.",[28,118,119,120,121,122],"Anxiety","Depression","Stress","Well-Being","Enjoyment",[124,125,126,127,128,129,130,121,131,132,133],"Latin Dance","Primary School Children","School-Based Intervention","Physical Activity","Physical Activity Enjoyment","Psychological Health","Mental Health","Rumba","Cha-Cha","Jive","NOT_YET_RECRUITING","2026-08-06",{"date":137,"type":40},"2026-08-10",{"date":139,"type":21},"2026-09-01",{"date":141,"type":21},"2026-11-30",{"name":143,"class":47},"Xu Shuishui",{"id":145,"slug":146,"hasResults":12,"nctId":147,"briefTitle":148,"officialTitle":149,"acronym":150,"eligibilityCriteria":151,"healthyVolunteers":57,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":152,"targetDuration":4,"studyType":22,"phases":154,"briefSummary":155,"conditions":156,"keywords":158,"overallStatus":134,"whyStopped":4,"lastUpdateSubmitDate":160,"lastUpdatePostDateStruct":161,"startDateStruct":163,"completionDateStruct":165,"leadSponsor":167,"locationsCount":48},"100650902","the-wise-study-whatsapp-intervention-for-sleep-in-the-elderly-100650902","NCT07751458","The WISE Study (WhatsApp Intervention for Sleep in the Elderly)","The WISE Study (WhatsApp Intervention for Sleep in the Elderly): Targeting Insomnia and Loneliness With a Digital Booklet","WISE","Inclusion Criteria:\n\n* Elderly individuals diagnosed with loneliness\n* Reported experiencing sleep disturbances in the past 2 weeks, either continuously or intermittently\n* Experiencing insomnia with a total score of ≥ 8 on the Indonesian version of the Insomnia Severity Index (ISI) during screening\n* Able to communicate in Indonesian\n\nExclusion Criteria:\n\n* Elderly individuals with dementia, delirium, severe mental retardation, or cognitive impairment that prevents them from understanding or assessing their own sleep experience.\n* Currently using new sleeping medication\u002Fstimulants",{"count":153,"type":21},50,[24],"Sleep hygiene education is an educational effort to teach healthy sleep habits and behaviors to improve sleep quality, duration, and regularity naturally without the use of medication; however, this approach has not been established in Indonesia. This study aims to establish a sleep hygiene education care model among lonely older adults with insomnia in Indonesia and to examine the immediate effects of the WISE Study (WhatsApp Intervention for Sleep in the Elderly) led by nurses to older adults loneliness with insomnia using a Digital Booklet. In this assessor-blinded, randomized controlled trial, participants will be randomly allocated to either the nurse-led WISE experimental group or the control group provided with usual care. The outcomes will include sleep parameters measured using the Indonesian version of the Insomnia Severity Index (ISI), Generalized Anxiety Disorder-7 (GAD-7), Geriatric Depression Scale-Short Form (GDS-SF), Brief Fatigue Inventory (BFI), Epworth Sleepiness Scale (ESS), and sleep diaries. The questionnaires will be assessed at pre-treatment, post-treatment, and one-month follow-up. Generalized estimating equations will be used to test the research hypotheses. Questionnaires will be assessed at pre-treatment, post-treatment, and one-month follow-up. We hypothesized that older adults who were loneliness with insomnia who underwent nurse-led WISE would experience greater improvements in sleep quality compared to participants in a control group who received usual care.",[28,157],"Insomnia",[159,32,28,157],"WiSE","2026-08-05",{"date":162,"type":40},"2026-08-07",{"date":164,"type":21},"2026-07-30",{"date":166,"type":21},"2026-12-03",{"name":168,"class":47},"Halu Oleo University",{"id":170,"slug":171,"hasResults":12,"nctId":172,"briefTitle":173,"officialTitle":174,"acronym":175,"eligibilityCriteria":176,"healthyVolunteers":12,"sex":17,"minAge":112,"maxAge":4,"enrollmentInfo":177,"targetDuration":4,"studyType":22,"phases":179,"briefSummary":180,"conditions":181,"keywords":184,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":160,"lastUpdatePostDateStruct":190,"startDateStruct":191,"completionDateStruct":192,"leadSponsor":194,"locationsCount":48},"100639882","creating-encounters-between-generations---together-instead-of-alone-gemse-100639882","NCT07581171","Creating Encounters Between Generations - Together Instead of Alone (GemsE)","Creating Encounters: Generations in Action - Together Instead of Alone (GemsE)","GemsE","Inclusion Criteria:\n\n* Older adults aged 60 years and older who are residents of Hamburg\n* Children and adolescents aged 12 to 21 years with at least one parent with a mental illness and who are residents of Hamburg\n* Sufficient German language proficiency\n* Ability and willingness to provide informed consent to participate in the study\n\nExclusion Criteria:\n\n* Children and adolescents with severe acute psychological symptoms requiring inpatient treatment, including acute suicidality, acute substance use, or acute psychotic symptoms\n* Older adults with acute psychological crises or untreated severe mental illness preventing reliable participation\n* Older adults with cognitive impairment or dementia preventing reliable participation in the intervention",{"count":178,"type":21},80,[24],"Elderly people and children and young people (CYP) and from families with mentally ill parents are particularly affected by loneliness. The GemsE project is investigating whether intergenerational mentoring between seniors and children or young people helps to reduce loneliness and improve the mental well-being and quality of life of both groups. The aim of the study is to scientifically record the effect of these sponsorships and to find out how such encounters can be successfully organized.",[28,182,183],"Mental Well-being","Health-related Quality of Life",[185,186,187,188,189],"elderly people","children of parents with mental illness","loneliness","psychosocial health","intergenerational tandems",{"date":137,"type":40},{"date":139,"type":21},{"date":193,"type":21},"2026-12-01",{"name":195,"class":47},"Universitätsklinikum Hamburg-Eppendorf",{"id":197,"slug":198,"hasResults":12,"nctId":199,"briefTitle":200,"officialTitle":200,"acronym":201,"eligibilityCriteria":202,"healthyVolunteers":57,"sex":17,"minAge":58,"maxAge":4,"enrollmentInfo":203,"targetDuration":4,"studyType":22,"phases":204,"briefSummary":205,"conditions":206,"keywords":208,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":210,"lastUpdatePostDateStruct":211,"startDateStruct":212,"completionDateStruct":214,"leadSponsor":216,"locationsCount":48},"100646560","babacare-testing-a-care-copilot-100646560","NCT07689526","BabaCare: Testing a Care Copilot","Baba","Inclusion Criteria:\n\n* Lives alone\n* Responds \"occasionally\" or \"most\" to the exhaustion questionnaire:\n\n  1. \"How often in the last week did you feel that everything you did was an effort?\"\n  2. \"How often in the last week did you feel that you could not get going?\"\n* Willingness and ability to regularly engage with Baba for 12 weeks\n\nExclusion Criteria:\n\n* Significant cognitive impairment that prevents consent or participation\n* Inability to communicate via SMS or phone\n* Severe hearing or speech impairment precluding use of voice interaction",{"count":60,"type":21},[24],"Baba is a novel AI \"care copilot\" designed to improve emotional well-being, cognitive stimulation, and social connection through emotionally present conversations, proactive engagement, and personalized communication. Unlike many existing solutions, Baba operates through SMS text and voice calls, requiring no apps, Wi-Fi, or new devices, making it particularly accessible to older adults.",[28,207],"Mood",[209],"Loneliness in older adults","2026-08-04",{"date":160,"type":40},{"date":213,"type":40},"2026-07-13",{"date":215,"type":21},"2027-06",{"name":217,"class":47},"Johns Hopkins University",{"id":219,"slug":220,"hasResults":12,"nctId":221,"briefTitle":222,"officialTitle":223,"acronym":224,"eligibilityCriteria":225,"healthyVolunteers":12,"sex":226,"minAge":227,"maxAge":4,"enrollmentInfo":228,"targetDuration":4,"studyType":22,"phases":230,"briefSummary":231,"conditions":232,"keywords":239,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":210,"lastUpdatePostDateStruct":251,"startDateStruct":252,"completionDateStruct":254,"leadSponsor":256,"locationsCount":48},"100610142","postpartum-education-via-artificial-intelligence-for-recovery-and-loneliness-a-randomized-controlled-trial-100610142","NCT07223736","Postpartum Education Via Artificial Intelligence for Recovery and Loneliness: A Randomized Controlled Trial","Postpartum Education Via Artificial Intelligence for Recovery and Loneliness (PEARL): A Randomized Controlled Trial","PEARL","Inclusion Criteria:\n\n1. Has the capacity to provide informed consent\n2. Stated willingness to comply with all study procedures and availability for the duration of the study\n3. Postpartum persons, aged \\>18 years old\n4. Primiparous\n5. Vaginal or cesarean delivery\n6. English Speaking\n7. Internet access and proficiency of internet access\n8. Access to a smartphone\n9. Postpartum 2-6 weeks\n\nExclusion Criteria:\n\n1. Multiparous\n2. Major neonatal anomaly\n3. Delivery \\\u003C 34 weeks gestational age\n4. Intrauterine fetal demise (IUFD)\n5. Enrollment in any interfering studies\n6. Unanticipated NICU admission\n7. Discharge home without live baby\n8. Surrogates\u002Fgestational carrier\n9. Birthing individuals with baby placed for adoption\n10. Currently pregnant\n11. Psychiatric history requiring psychiatric hospitalization prior to delivery\n12. Other psychiatric conditions needing immediate attention and intervention as determined by study team and\u002For treatment team","FEMALE","18 Years",{"count":229,"type":21},130,[24],"The goal of this clinical trial is to learn whether a postpartum chatbot powered by generative artificial intelligence (genAI) can help new mothers get better pelvic floor health information and feel less lonely after childbirth.\n\nThe main questions this study aims to answer are:\n\n* Does using the chatbot improve postpartum pelvic floor health knowledge?\n* Does using the chatbot help reduce feelings of loneliness during the postpartum period?\n* Does using the chatbot impact pelvic floor symptoms?\n\nResearchers will compare standard postpartum care to standard care plus the chatbot.\n\nParticipants will:\n\nBe assigned by chance (like flipping a coin) to standard postpartum care with or without access to the chatbot.\n\nIf in the chatbot group, participants will receive education and support via the chatbot over a 4-week period.\n\nBoth groups will complete questionnaires to measure their pelvic floor knowledge, pelvic floor symptoms, feelings of loneliness, depression, infant bonding, perceived social support, adverse childhood experiences, and peri-traumatic distress.\n\nThe chatbot was created by urogynecology experts in collaboration with UC San Diego computer science and biomedical informatics researchers. The chatbot is designed to give new mothers personalized, evidence-based information and support in real time.",[233,28,234,130,119,235,236,237,238],"Pelvic Floor Disorder","Postpartum","Peritraumatic Distress","Women","Artificial Intelligence (AI)","Chatbot",[187,240,241,242,243,244,245,246,247,248,249,250],"postpartum","pelvic floor disorder","mental health","depression","peritraumatic distress","artificial intelligence","AI","chatbot","LLM","women","large language model",{"date":160,"type":40},{"date":253,"type":40},"2026-01-08",{"date":255,"type":21},"2026-11-01",{"name":257,"class":47},"University of California, San Diego",{"id":259,"slug":260,"hasResults":12,"nctId":261,"briefTitle":262,"officialTitle":263,"acronym":4,"eligibilityCriteria":264,"healthyVolunteers":12,"sex":17,"minAge":58,"maxAge":4,"enrollmentInfo":265,"targetDuration":4,"studyType":22,"phases":267,"briefSummary":268,"conditions":269,"keywords":277,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":210,"lastUpdatePostDateStruct":281,"startDateStruct":282,"completionDateStruct":284,"leadSponsor":286,"locationsCount":48},"100585459","geriatric-trauma-care-program-for-living-alone-older-adults-with-injuries-100585459","NCT06902636","Geriatric Trauma Care Program for Living Alone Older Adults With Injuries","Patient Experience of Older Adults Living Alone With Injuries and Long-Term Effects of Geriatric Trauma Care Program for Living Alone Older Adults With Injuries","Inclusion Criteria:\n\n1. willing to join this study for three months\n2. with limb injuries\n3. living alone in a household\n4. aged 65 years old or older\n5. independent before a traumatic injury\n6. having a smartphone.\n\nExclusion Criteria:\n\n1. with an ISS greater than 16 (severe injuries)\n2. having cognitive impairments\n3. diagnosed with psychiatric illness",{"count":266,"type":21},90,[24],"To examine the long-term effects of the Geriatric Trauma Care Program (GTCP) regarding pain, functional disability, depression, loneliness, and health-related quality of life among older adults with traumatic injuries who live alone.",[270,271,272,273,274,275,276,28],"Limb Injury","Older Adults","Geriatric","Pain","Geriatric Depression","Barthel Index","Quality of Life",[278,279,280,187],"Limb injury","geriatric trauma","older adults",{"date":135,"type":40},{"date":283,"type":40},"2025-03-27",{"date":285,"type":21},"2026-10-31",{"name":287,"class":47},"Kaohsiung Medical University",{"id":289,"slug":290,"hasResults":12,"nctId":291,"briefTitle":292,"officialTitle":293,"acronym":294,"eligibilityCriteria":295,"healthyVolunteers":57,"sex":17,"minAge":296,"maxAge":85,"enrollmentInfo":297,"targetDuration":4,"studyType":22,"phases":299,"briefSummary":300,"conditions":301,"keywords":304,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":310,"lastUpdatePostDateStruct":311,"startDateStruct":313,"completionDateStruct":315,"leadSponsor":317,"locationsCount":48},"100629370","social-media-diet-and-psychological-outcomes-in-university-students-100629370","NCT07473791","Social Media Diet and Psychological Outcomes in University Students","The Effect of a Social Media Diet on Loneliness, Fear of Missing Out, and Sleep Quality Among University Students: A Randomized Controlled Trial","The Effect of","Inclusion Criteria:\n\n* Being between the ages of 18-25.\n* Being a student at Gumushane University Kelkit Sema Dogan Vocational School of Health Services.\n* Having a daily social media usage time of at least 2 hours (verified by smartphone screen time settings).\n* Owning a smartphone (Android or iOS).\n* Volunteering to participate in the study and providing written informed consent.\n\nExclusion Criteria:\n\n* Having a diagnosed clinical sleep disorder (e.g., sleep apnea, chronic insomnia) or using prescribed sleep medication.\n* Having a diagnosed psychiatric disorder that may interfere with social media use or perception of loneliness.\n* Use of other digital detox or time-management applications during the study period.\n* Being unable to provide weekly screen time screenshots.\n* Planning to change smartphone device during the 4-week intervention period.","17 Years",{"count":298,"type":21},70,[24],"This study aims to examine the effect of a social media diet intervention on loneliness, fear of missing out (FoMO), and sleep quality among university students. Excessive social media use has been associated with several negative psychological outcomes, including increased loneliness, heightened FoMO, and poor sleep quality.\n\nIn this randomized controlled trial, university students will be randomly assigned to either an experimental group or a control group. Participants in the experimental group will follow a social media diet intervention that involves limiting daily social media use for a specified period, while participants in the control group will continue their usual social media use without restrictions.\n\nLoneliness, FoMO, and sleep quality will be measured at baseline and after the intervention using validated scales. The findings of this study are expected to provide evidence on whether reducing social media use can improve psychological well-being and sleep quality among university students.",[28,302,303],"Fear of Missing Out","Sleep Quality",[305,306,307,308,309],"Social Media Diet","Digital Detox","University Students","Behavioral Intervention","Randomized Controlled Trial","2026-07-31",{"date":312,"type":40},"2026-08-03",{"date":314,"type":40},"2026-03-10",{"date":316,"type":21},"2026-08",{"name":318,"class":47},"Gümüşhane Universıty",{"id":320,"slug":321,"hasResults":12,"nctId":322,"briefTitle":323,"officialTitle":324,"acronym":4,"eligibilityCriteria":325,"healthyVolunteers":12,"sex":17,"minAge":227,"maxAge":326,"enrollmentInfo":327,"targetDuration":4,"studyType":22,"phases":329,"briefSummary":330,"conditions":331,"keywords":336,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":342,"lastUpdatePostDateStruct":343,"startDateStruct":345,"completionDateStruct":347,"leadSponsor":349,"locationsCount":48},"100642919","steps---stress-training-and-engagement-via-phone-based-systems-100642919","NCT07639697","STEPS - Stress Training and Engagement Via Phone-Based Systems","Mindfulness Training and Respiration Biosignal Feedback - Study 3","Inclusion Criteria:\n\n* Ages 18-30 years of Age\n* Fluent in English\n* Psychological distress\n* Interested in completing smartphone guided training sessions remotely for 14 days\n* Willing and able to wear physiological monitoring equipment\n* Willing to be randomized to one of three conditions\n* Located in the United States\n* Access to a smartphone without snapdragon processors to complete guided training sessions\n\nExclusion Criteria:\n\n* Currently pregnant\n* Current or previous diagnosis with psychosis or schizophrenia","30 Years",{"count":328,"type":21},300,[24],"This study will evaluate engagement, usability, and psychological outcomes associated with participation in smartphone-based stress management or mindfulness training program among young adults. The study will compare multiple versions of a digital training program delivered through the Equa mobile application.\n\nParticipants will be individually randomized to one of several app-based training programs using a stratified randomization procedure. Each program consists of guided daily lessons completed over a 14-day period and is designed to support stress management and well-being through structured skill development activities.\n\nPrimary objectives include evaluating user satisfaction and usability of the digital platform and assessing changes in mindfulness-related skills and mental distress over time.\n\nParticipants will:\n\nComplete surveys assessing demographics and psychological well-being at baseline, post-intervention, and one-month follow-up.\n\nComplete a 14-day smartphone-delivered training program consisting of guided lessons while physiological data are collected using wearable sensors.\n\nSome participants may receive additional in-app features designed to support personalized learning or engagement with training lessons.\n\nSome participants will complete brief questionnaires before and after selected lessons to assess short-term changes associated with lesson participation.",[332,333,334,335,28],"Psychological Distress","Mindfulness Skills","Usability Satisfaction","Program Engagement",[337,242,338,339,340,341],"young adults","well-being","mindfulness skills","psychological distress","stress management","2026-07-17",{"date":344,"type":40},"2026-07-20",{"date":346,"type":40},"2026-06-17",{"date":348,"type":21},"2027-07",{"name":350,"class":351},"Equa Health","INDUSTRY",{"id":353,"slug":354,"hasResults":12,"nctId":355,"briefTitle":356,"officialTitle":356,"acronym":82,"eligibilityCriteria":357,"healthyVolunteers":12,"sex":17,"minAge":358,"maxAge":4,"enrollmentInfo":359,"targetDuration":4,"studyType":22,"phases":360,"briefSummary":361,"conditions":362,"keywords":363,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":364,"lastUpdatePostDateStruct":365,"startDateStruct":366,"completionDateStruct":368,"leadSponsor":370,"locationsCount":48},"100647350","structured-opportunities-for-connection-to-improve-aging-related-loneliness-100647350","NCT07708844","Structured Opportunities for Connection to Improve Aging-related Loneliness","Inclusion Criteria:\n\n* Patients 55 years of age or older attending an outpatient visit at an Endeavor Health primary care practice site in Evanston, IL.;\n* Screened positive for loneliness (often, some of the time, or occasionally) using the one-item Loneliness Screener;\n* Able to provide informed consent for study participation;\n* Speaks and understands English language.\n\nExclusion Criteria:\n\n* Prisoners, pregnant women, children\n* Persons those who are determined to be unable to provide consent\n* Non-English speakers","55 Years",{"count":153,"type":21},[24],"The goal of this early phase clinical trial is to determine the impact of participation in planned social activities among adults 55 years of age or older, who report feelings of loneliness. The main questions the study aims to answer are:\n\n* With the availability of a personalized community activity plan, will patients with loneliness participate in two hours of social activity each week?\n* Will 2 hours\u002Fweek of planned social activities in the community reduce individual reports of loneliness? Participants will meet with a community coordinator to identify community activities of interest to them and then participate, in-person or virtually, in these activities over a 6 month period. Patients will complete a series of surveys at the start of the study and then at 1, 3 and 6 months later.",[28],[28],"2026-07-16",{"date":342,"type":40},{"date":367,"type":40},"2026-05-01",{"date":369,"type":21},"2027-05-01",{"name":371,"class":47},"Endeavor Health",{"id":373,"slug":374,"hasResults":12,"nctId":375,"briefTitle":376,"officialTitle":377,"acronym":4,"eligibilityCriteria":378,"healthyVolunteers":57,"sex":17,"minAge":58,"maxAge":379,"enrollmentInfo":380,"targetDuration":4,"studyType":22,"phases":381,"briefSummary":382,"conditions":383,"keywords":384,"overallStatus":134,"whyStopped":4,"lastUpdateSubmitDate":387,"lastUpdatePostDateStruct":388,"startDateStruct":389,"completionDateStruct":391,"leadSponsor":393,"locationsCount":48},"100647664","mindfulness-for-lonely-older-adults-with-emigrant-children-100647664","NCT07711860","Mindfulness for Lonely Older Adults With Emigrant Children","Feasibility and Acceptability of Implementation of Mindfulness-Based Intervention for Community-Dwelling Older Adults With Emigrant Children Suffering From Loneliness: A Pilot Randomized Controlled Trial","Inclusion Criteria:\n\n1. Chinese adults aged 65 to 75 years,\n2. able to communicate and understand Cantonese (class will be held in Cantonese),\n3. OAs with or without emigrant children,\n4. feeling of loneliness (3-item UCLA ≥6) \\[25\\], and\n5. living in public housing, reliant on pension, savings, or living in subvented housing.\n\nExclusion Criteria:\n\n1. Acute or severe physical symptoms such as impaired mobility, COPD or respiratory failure, uncontrolled epilepsy, and severe chronic pain syndrome,\n2. Abbreviated Mental Test (AMT)\\\u003C 6 \\[26\\],\n3. met DSM-V TR criteria for treated or untreated major depressive disorder, bipolar disorder, cyclothymic disorder and\u002For on regular medication treatment,\n4. have significant suicidal risk, and\n5. previous experience in instructor-led mindfulness training within the half year prior to the commencement of the study.","75 Years",{"count":266,"type":21},[24],"This study is to examine the feasibility of a proposed mindfulness-based intervention (MBI) and study methodology for future main study.",[28,303,276,120],[385,187,386],"Mindfulness-based intervention","older adults with emigrant children","2026-07-14",{"date":342,"type":40},{"date":390,"type":21},"2026-10-01",{"date":392,"type":21},"2028-03-31",{"name":394,"class":47},"Hong Kong Metropolitan University",{"id":396,"slug":397,"hasResults":12,"nctId":398,"briefTitle":399,"officialTitle":399,"acronym":4,"eligibilityCriteria":400,"healthyVolunteers":57,"sex":17,"minAge":58,"maxAge":4,"enrollmentInfo":401,"targetDuration":4,"studyType":22,"phases":403,"briefSummary":404,"conditions":405,"keywords":407,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":414,"lastUpdatePostDateStruct":415,"startDateStruct":417,"completionDateStruct":419,"leadSponsor":421,"locationsCount":48},"100602404","alleviating-loneliness-in-older-adults-living-in-poverty-a-multi-level-intervention-100602404","NCT07123064","Alleviating Loneliness in Older Adults Living in Poverty: A Multi-level Intervention","Inclusion Criteria:\n\n* aged 65 years or older\n* living in poverty (defined: inability to afford at least 5 items on the material deprivation index)\n* proficiency in spoken Cantonese\n* experiencing loneliness (defined: score of ≥ 6 on the 3-item UCLA Loneliness Scale)\n\nExclusion Criteria:\n\n* cognitive impairments, psychiatric disorders, learning disabilities, or active suicidal ideation\n* actively participating in other psychotherapy or psychosocial interventions in the past 1 year\n\nExclusion Criteria:\n\n\\-",{"count":402,"type":21},1344,[24],"The study aims to reduce loneliness among Hong Kong Chinese older adults living in poverty with a multi-level intervention involving components at the individual, interpersonal, and community levels.",[28,406],"Poverty",[28,406,408,271,409,410,411,412,413],"Cluster Randomized Controlled Trials","Mindfulness","SOLUS-D Programme","Group 4 Health","Neighbour Every Day","Hong Kong","2026-07-06",{"date":416,"type":40},"2026-07-08",{"date":418,"type":40},"2026-04-01",{"date":420,"type":21},"2029-05-31",{"name":422,"class":47},"Education University of Hong Kong",{"id":424,"slug":425,"hasResults":12,"nctId":426,"briefTitle":427,"officialTitle":427,"acronym":4,"eligibilityCriteria":428,"healthyVolunteers":57,"sex":17,"minAge":429,"maxAge":58,"enrollmentInfo":430,"targetDuration":4,"studyType":22,"phases":432,"briefSummary":434,"conditions":435,"keywords":437,"overallStatus":134,"whyStopped":4,"lastUpdateSubmitDate":439,"lastUpdatePostDateStruct":440,"startDateStruct":442,"completionDateStruct":444,"leadSponsor":446,"locationsCount":48},"100646290","phase-1-the-effects-of-psilocybin-on-social-connectedness-100646290","NCT07693153","The Effects of Psilocybin on Social Connectedness","Inclusion Criteria:\n\n* Medically healthy\n* Ability to provide consent\n* High loneliness defined by the UCLA-3 Loneliness Scale\n* Willingness to comply with all study procedures and availability for the duration of the study\n\nExclusion Criteria:\n\n* Any unstable medical condition, psychiatric disorder, or circumstance that, in the opinion of the investigator, could compromise participant safety, interfere with study participation, or hinder the participant's ability to comply with study procedures and requirements\n* Positive pregnancy test or women who are breastfeeding\n* Any contraindication to MRI such as a pacemaker or metal implants","21 Years",{"count":431,"type":21},51,[433],"PHASE1","The study is a randomized, double-blind, placebo-controlled, expectancy-controlled, mechanistic trial. This study looks to explore whether a single dose of psilocybin (25mg) reduces amygdala reactivity to negative socioemotional stimuli during the Facial Emotion Recognition Task (FERT) compared to a placebo in adults who feel lonely or those with unresolved grief symptoms.",[28,436],"Grief",[438],"Social Connectedness","2026-07-03",{"date":441,"type":40},"2026-07-09",{"date":443,"type":21},"2026-08-31",{"date":445,"type":21},"2031-12-15",{"name":447,"class":47},"Yale University",{"id":449,"slug":450,"hasResults":12,"nctId":451,"briefTitle":452,"officialTitle":452,"acronym":4,"eligibilityCriteria":453,"healthyVolunteers":12,"sex":17,"minAge":358,"maxAge":4,"enrollmentInfo":454,"targetDuration":4,"studyType":22,"phases":455,"briefSummary":456,"conditions":457,"keywords":460,"overallStatus":134,"whyStopped":4,"lastUpdateSubmitDate":463,"lastUpdatePostDateStruct":464,"startDateStruct":466,"completionDateStruct":468,"leadSponsor":469,"locationsCount":48},"100644029","social-prescribing-for-a-mindful-lifestyle-100644029","NCT07669805","Social Prescribing for a Mindful Lifestyle","Inclusion Criteria:\n\n* People aged 55 years or older.\n* People with a Geriatric Depression Scale (GDS-15) score of 7-10 or a UCLA Loneliness Scale Version 3 score of 35-64.\n* People can understand the research process, meet the requirements of the research, and can sign the informed consent and participate in the project.\n\nExclusion Criteria:\n\n* People that are unable to cooperate with the project or follow-up.\n* According to the PI's judgment, people with severe or poorly controlled conditions include ongoing acute diseases, severe infections, severe abnormal laboratory tests, or serious medical conditions with the following systems: cardiovascular, pulmonary, hepatic, nervous, mental, metabolic, renal, musculoskeletal, gastrointestinal, etc.\n* People with severe depression, risk of self-harm, severe cognitive impairment (dementia), visual or hearing impairment, and disabilities that prevent the completion of the project and assessment.\n* People are currently or expected to join any other physical training courses or nutrition intervention plans during the project period.\n* Others are based on the judgment of the PI that participating in this project may adversely affect the safety of the subjects, hinder the progress of the experiment, or interfere with the evaluation of the outcomes of the project.",{"count":153,"type":21},[24],"The goal of this clinical trial is to evaluate the effectiveness of an 8-week mindfulness lifestyle social prescribing program in community-dwelling older adults aged 55 and older. The main questions it aims to answer are:\n\nTo establish a mindfulness lifestyle social prescribing model applied to the psychological and social health promotion of middle-aged and older populations.\n\nTo evaluate the effectiveness of the intervention on improving depressive symptoms, loneliness, and quality of life in this population.\n\nParticipants will receive an 8-week group intervention program, with each weekly session lasting approximately 3 hours. The structured curriculum integrates mindfulness awareness, body scanning, mindfulness stretching, breathing training, healthy dietary education, and art practices (such as herbal therapy and leaf printing). Researchers will collect and evaluate data from pre- and post-intervention assessments to measure changes in depressive symptoms, loneliness risk, and overall quality of life.",[458,28,459],"Depression and\u002For Anxiety in the Mild-to-moderate Range","Social Isolation",[409,271,461,276,462],"Lifestyle Medicine","Social Prescribing","2026-06-21",{"date":465,"type":40},"2026-06-25",{"date":467,"type":21},"2026-07-01",{"date":44,"type":21},{"name":470,"class":47},"Buddhist Tzu Chi General Hospital",{"id":472,"slug":473,"hasResults":12,"nctId":474,"briefTitle":475,"officialTitle":476,"acronym":477,"eligibilityCriteria":478,"healthyVolunteers":57,"sex":17,"minAge":227,"maxAge":4,"enrollmentInfo":479,"targetDuration":4,"studyType":481,"phases":4,"briefSummary":482,"conditions":483,"keywords":487,"overallStatus":134,"whyStopped":4,"lastUpdateSubmitDate":491,"lastUpdatePostDateStruct":492,"startDateStruct":494,"completionDateStruct":496,"leadSponsor":498,"locationsCount":4},"100641745","student-precarity-and-psychiatry-100641745","NCT07618208","Student Precarity and Psychiatry","Impact of Precarity on the Emergence of Psychiatric Disorders and the Use of Care Among Students","PEPSY","Inclusion Criteria:\n\n* Student enrolled at Paris Sciences et Lettres University (PSL, 17,000 students) or the Faculty of Health Sciences at Paris Cité University (UPC, 28,000 students),\n* Aged 18 or over,\n* Fluent in French,\n* Affiliated to a health insurance.\n\nExclusion Criteria:\n\n* Applicants under the age of 18,\n* Not enrolled at PSL universities or the UPCS Faculty of Health,\n* Insufficient level of French.",{"count":480,"type":21},45000,"OBSERVATIONAL","Since the COVID-19 pandemic, mental health disorders have increased significantly, particularly among young people. In France, the proportion of young people aged 18 to 25 suffering from depression almost doubled between 2017 and 2021. This phenomenon particularly affects students, who are already identified as being at greater risk of mental health disorders than the general population. Medical students seem to be particularly vulnerable: in 2021, a national study showed very high rates of depression and suicidal thoughts in this population. The main factor associated with depression was the feeling of financial hardship.\n\nStudents often face multiple forms of insecurity. Financially, they have limited resources and struggle to cover their basic needs such as housing, food and healthcare. Socially, many experience significant isolation, particularly when they are away from their families or under pressure from their studies. All of this has a significant impact on their mental health. Unfortunately, many students do not seek help due to lack of time, resources, or awareness of support services. The 2021 study showed that only one-third of medical students suffering from depression received appropriate treatment.\n\nThe aim of our study is to assess the impact of precariousness on the onset of psychiatric disorders and on the use or non-use of healthcare services.\n\nOur study will involve nearly 45,000 students from PSL and UPC universities. It is based on a longitudinal cohort (via questionnaires) over three years. The aim is to identify precisely the different aspects of student precariousness (housing, transport, isolation, economic difficulties, etc.) and their link with psychological distress. The study will measure the extent of the phenomenon and identify modifiable factors that could be targeted by preventive measures. The results will enable us to better target preventive measures and propose concrete solutions to improve students' well-being and promote their success.",[484,485,486,28],"Depressive Disorder, Major","Generalized Anxiety Disorder","Suicidal Ideation",[488,119,489,490],"Students","Use of care","Precarity","2026-06-11",{"date":493,"type":40},"2026-06-15",{"date":495,"type":21},"2026-09",{"date":497,"type":21},"2028-11",{"name":499,"class":47},"Assistance Publique - Hôpitaux de Paris",{"id":501,"slug":502,"hasResults":12,"nctId":503,"briefTitle":504,"officialTitle":505,"acronym":4,"eligibilityCriteria":506,"healthyVolunteers":12,"sex":17,"minAge":227,"maxAge":4,"enrollmentInfo":507,"targetDuration":509,"studyType":481,"phases":4,"briefSummary":510,"conditions":511,"keywords":513,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":491,"lastUpdatePostDateStruct":517,"startDateStruct":518,"completionDateStruct":520,"leadSponsor":522,"locationsCount":524},"100618546","lonely-in-depression-100618546","NCT07333027","Lonely in Depression","Effects of Loneliness in the Treatment of Depression","Inclusion Criteria:\n\n* primary diagnosis of depression according to ICD-10 (F32 or F33), as diagnosed by a physician or clinical psychologist in conjunction with the M.I.N.I. Mini-International Neuropsychiatric Interview diagnostic tools\n* inpatient elective or emergency admission to one of the two psychiatric clinics; - age over 18 years\n* sufficient understanding of spoken and written German\n* informed voluntary consent\n\nExclusion Criteria:\n\n* a current lack of capacity to provide consent (e.g., pronounced psychotic symptoms, stuporous depressive syndrome, and thought constriction to suicidality)\n* previous participation in the study\n* pregnancy or breastfeeding\n* inpatient stay of less than 7 days, even if the patients initially met the inclusion criteria.",{"count":508,"type":21},200,"3 Months","The goal of this prospective study is to better understand the link between loneliness and depression in the inpatient psychiatric treatment of depression. It aims to answer:\n\nDo lonely and not lonely persons benefit the same way from inpatient depression treatment? Is loneliness a clinical relevant factor in inpatient treatment of depression? What are the underlying biopsychosocial mechanisms?\n\nParticipants will be asked to do some\n\n* self-report questionnaires\n* clinical interview\n* biosampling (blood, saliva, stool) at three main measurement timepoints (1. begin of inpatient treatment, 2. day of discharge, 3. three months after discharge).",[512,28],"Depression Disorder",[187,243,514,515,516],"prospective","biosampling","clinical",{"date":493,"type":40},{"date":519,"type":40},"2026-02-05",{"date":521,"type":21},"2027-09",{"name":523,"class":47},"Friedrich-Alexander-Universität Erlangen-Nürnberg",2,{"id":526,"slug":527,"hasResults":12,"nctId":528,"briefTitle":529,"officialTitle":530,"acronym":4,"eligibilityCriteria":531,"healthyVolunteers":57,"sex":17,"minAge":58,"maxAge":4,"enrollmentInfo":532,"targetDuration":4,"studyType":22,"phases":533,"briefSummary":534,"conditions":535,"keywords":538,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":543,"lastUpdatePostDateStruct":544,"startDateStruct":546,"completionDateStruct":548,"leadSponsor":549,"locationsCount":48},"100643409","music-breathing-in-enhancing-resilience-among-elders-at-risk-of-mental-health-problems-100643409","NCT07631845","Music Breathing in Enhancing Resilience Among Elders at Risk of Mental Health Problems","Effects of a Mindfulness-based Music Breathing Intervention in Enhancing Resilience Among Community-dwelling Elders at Risk of Mental Health Problems: A Pilot Randomised Controlled Trial","Inclusion Criteria:\n\n* Aged 65 years or above\n* Able to read Chinese and communicate in Cantonese\u002FMandarin.\n* Has mild to moderate anxiety and\u002For depressive symptoms, based on the - Hospital Anxiety and Depression Scale (HADS) (i.e., a score of 8 or higher on either the anxiety or depression subscale)\n\nExclusion Criteria:\n\n* Partcipants will be excluded if they have cognitive impairment, hearing loss, severe depression, known mental illness, or chronic illness.",{"count":60,"type":21},[24],"The goal of this pilot randomised controlled trial is to examine the effects of a mindfulness-based music breathing intervention in enhancing resilience (primary outcome), and in reducing anxiety, depressive symptoms, loneliness, and improving health-related quality of life (secondary outcomes) among community-dwelling older adults at risk of mental health problems.\n\nIt is hypothesised that compared with the control group, participants in the intervention group will report enhanced resilience, reduced anxiety, depressive symptoms, and loneliness, and improved health-related quality of life immediately post-intervention.",[536,118,537,28,183],"Resilience","Depressive Symptom",[409,539,540,541,536,542],"Msuic","Breathing","Community-dwelling elders","Mental health","2026-06-07",{"date":545,"type":40},"2026-06-10",{"date":547,"type":40},"2026-06-08",{"date":443,"type":21},{"name":550,"class":47},"Chinese University of Hong Kong",{"id":552,"slug":553,"hasResults":12,"nctId":554,"briefTitle":555,"officialTitle":556,"acronym":4,"eligibilityCriteria":557,"healthyVolunteers":12,"sex":17,"minAge":227,"maxAge":326,"enrollmentInfo":558,"targetDuration":4,"studyType":22,"phases":560,"briefSummary":561,"conditions":562,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":563,"lastUpdatePostDateStruct":564,"startDateStruct":566,"completionDateStruct":568,"leadSponsor":569,"locationsCount":48},"100634743","evaluating-the-effectiveness-of-interventions-to-reduce-loneliness-in-chinese-young-adults-100634743","NCT07543653","Evaluating the Effectiveness of Interventions to Reduce Loneliness in Chinese Young Adults","Group-Based Positive Affect Intervention for Loneliness Reduction: A Randomized Controlled Trial in Chinese Young Adults","Inclusion Criteria:\n\n* aged 18 to 30 years\n* proficiency in Chinese (Cantonese or Mandarin)\n* experiencing loneliness (defined as a score of ≥ 6 on the 3-item UCLA Loneliness Scale)\n\nExclusion Criteria:\n\n* cognitive impairments\n* psychiatric disorders, learning disabilities, or active suicidal ideation\n* currently participating in other psychotherapy or psychosocial interventions aimed at enhancing well-being",{"count":559,"type":21},100,[24],"This study aims to evaluate the effectiveness of a group-based Positive Affect (PA) intervention compared to an active control condition, Social Skills Training (SST), in reducing loneliness among young adults in Hong Kong and mainland China. It further examines the psychological mechanisms underlying intervention effects, specifically the roles of positive affect and perceived social support as mediators, and rejection sensitivity as a moderator influencing both treatment responsiveness and outcome translation.",[28],"2026-05-14",{"date":565,"type":40},"2026-05-18",{"date":567,"type":40},"2026-03-31",{"date":316,"type":21},{"name":422,"class":47},{"id":571,"slug":572,"hasResults":12,"nctId":573,"briefTitle":574,"officialTitle":575,"acronym":4,"eligibilityCriteria":576,"healthyVolunteers":12,"sex":17,"minAge":577,"maxAge":227,"enrollmentInfo":578,"targetDuration":4,"studyType":22,"phases":580,"briefSummary":581,"conditions":582,"keywords":4,"overallStatus":134,"whyStopped":4,"lastUpdateSubmitDate":584,"lastUpdatePostDateStruct":585,"startDateStruct":586,"completionDateStruct":588,"leadSponsor":590,"locationsCount":4},"100638817","application-for-arts-based-social-prescribing-100638817","NCT07593443","Application for Arts-Based Social Prescribing","Member Engagement Application for Personalized Arts-based Social Prescriptions","Inclusion Criteria:\n\nParticipants must meet the following criteria:\n\n* Aged 15-18 years enrolled in Medicaid managed care\n* Positive screen for depression and\u002For anxiety (e.g., PHQ-2 or GAD-2 ≥ 3)\n* Currently own and easily operate a smartphone\n* Have a valid e-mail address checked regularly\n* English fluency, and\n* Have a stable treatment regimen for at least 30 days prior to baseline with no planned treatment changes.\n\nExclusion Criteria:\n\nParticipants will be excluded if they:\n\n* Endorse current suicidal ideation at study screening, defined as a response ≥ 1 (\"several days\") on Item 9 of the PHQ-9A\n* Initiate a new treatment regimen or plan on initiating a new treatment regimen (i.e., medication, psychotherapy, or mind-body interventions) at the time of enrollment.","15 Years",{"count":579,"type":21},230,[24],"The goal of this clinical trial is to learn if a personalized arts-based social prescribing program, Art Pharmacy, delivered through a mobile app (SocialRx App) can improve mental health and social connectedness in adolescents aged 15-18 with depression or anxiety enrolled in Medicaid managed care.\n\nThe main question it aims to answer is:\n\nCompared to stable treatment, does participation in the Art Pharmacy program through the SocialRx App improve depression, anxiety, social connectedness, and loneliness? Researchers will compare participants receiving the Art Pharmacy program and digital companion to those receiving stable treatment (no change to existing care) to evaluate its effects on mental health and social connectedness.\n\nParticipants will:\n\nBe randomly assigned to either the Art Pharmacy program delivered through the SocialRx App or a control group receiving stable treatment.\n\nComplete online surveys at baseline and follow-up time points (e.g., 3, 6, 9, and 12 months).\n\nIf assigned to the intervention group, Art Pharmacy, participants will receive monthly arts and cultural activity recommendations, attend activities, and interact with a care navigator delivered through the SocialRx App.",[583,118,28,438],"Depression in Adolescence","2026-05-13",{"date":565,"type":40},{"date":587,"type":21},"2026-05",{"date":589,"type":21},"2028-04",{"name":591,"class":351},"SocialRx Inc",{"id":593,"slug":594,"hasResults":12,"nctId":595,"briefTitle":596,"officialTitle":596,"acronym":4,"eligibilityCriteria":597,"healthyVolunteers":12,"sex":17,"minAge":227,"maxAge":598,"enrollmentInfo":599,"targetDuration":4,"studyType":22,"phases":600,"briefSummary":601,"conditions":602,"keywords":605,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":609,"lastUpdatePostDateStruct":610,"startDateStruct":612,"completionDateStruct":614,"leadSponsor":616,"locationsCount":48},"100629196","activating-social-resources-in-psychotherapy-seeking-individuals-effectiveness-and-timing-of-a-social-support-just-in-time-adaptive-intervention-100629196","NCT07471529","Activating Social Resources in Psychotherapy-Seeking Individuals: Effectiveness and Timing of a Social Support Just-in-Time Adaptive Intervention","Inclusion Criteria:\n\n* indicating to seek outpatient psychotherapy\n* elevated levels of self-reported depressive symptoms (Beck Depression Inventory-II (BDI) score \\> 13 (out of 63); Kühner et al., 2007)\n* owning a smartphone\n* signing the informed consent form\n\nExclusion Criteria:\n\n* first session for outpatient psychotherapy is scheduled within four weeks\n* suicidal ideation (values \\> 2 in BDI item 9)\n* presence of manic symptoms (Mood Disorder Questionnaire (MDQ) score \\> 7), - shift work\n* age below 18 or above 70","70 Years",{"count":20,"type":21},[24],"This study evaluates a Just-In-Time Adaptive Intervention (JITAI) aiming to foster social support processes for adults with elevated depressive symptoms awaiting outpatient psychotherapy. Utilizing a daily-level micro-randomized trial (MRT) design conducted over 21 days, participants are assessed six times daily. Participants are randomized across four conditions: (1) vulnerability-triggered, (2) vulnerability and receptivity-triggered, (3) support-need-triggered, and (4) a no-intervention control. The primary objective of this study is to evaluate the effectiveness of the JITAI in reducing daily depressive symptoms and increasing received social support (primary outcomes), as well as reducing daily loneliness and enhancing perceived social support (secondary outcomes). Furthermore, the study aims to compare the relative efficacy of three distinct triggering strategies to identify the most effective timing for intervention delivery.",[28,603,604],"Social Support","Depressive Symptoms",[603,28,606,607,608,604],"Just-in-Time Adaptive Intervention","JITAI","Ecological Momentary Intervention","2026-04-29",{"date":611,"type":40},"2026-04-30",{"date":613,"type":40},"2026-04-22",{"date":615,"type":21},"2026-12",{"name":617,"class":47},"University of Zurich",{"id":619,"slug":620,"hasResults":12,"nctId":621,"briefTitle":622,"officialTitle":623,"acronym":4,"eligibilityCriteria":624,"healthyVolunteers":12,"sex":17,"minAge":227,"maxAge":4,"enrollmentInfo":625,"targetDuration":4,"studyType":22,"phases":627,"briefSummary":628,"conditions":629,"keywords":630,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":636,"lastUpdatePostDateStruct":637,"startDateStruct":638,"completionDateStruct":640,"leadSponsor":641,"locationsCount":524},"100600291","enhancing-internet-delivered-cognitive-behaviour-therapy-with-additional-content-100600291","NCT07095582","Enhancing Internet-Delivered Cognitive Behaviour Therapy With Additional Content","Enhancing Therapist-Guided Internet-Delivered Cognitive Behaviour Therapy for Depression and Anxiety With Additional Content","Inclusion Criteria:\n\n* Saskatchewan resident,\n* Aged 18 years or older,\n* Self-reported difficulty with depression and\u002For anxiety,\n* Access to a computer (or other appropriate device) and the Internet,\n* Willingness to learn information and skills to self-manage mental health difficulties, and\n* Total score on UCLA-3 is greater than 5 at screening\n\nExclusion Criteria:\n\n* Current severe medical or psychiatric condition that requires immediate treatment (e.g. current mania or psychosis, actively suicidal or unable to keep themselves safe, medical condition requiring immediate surgery or other invasive treatment);\n* Unable to read and understand English (All content is provided in English and staff is English speaking)",{"count":626,"type":21},494,[24],"This study evaluates the effectiveness of additional content on loneliness offered alongside the Wellbeing Course - an internet-delivered cognitive behavioral therapy (ICBT) intervention for symptoms of depression and anxiety- in improving treatment outcomes for individuals with elevated scores on loneliness seeking treatment for depression and anxiety at a routine care online therapy clinic (the Online Therapy Unit). In this partially randomized control trial, the investigators aim to contribute to the literature by examining whether providing additional content on loneliness alongside the Wellbeing Course enhances engagement, satisfaction, and treatment outcomes among clients experiencing frequent loneliness compared to those completing only the Wellbeing Course. Over 8 weeks, participants will review course materials (with the addition of the loneliness content for those assigned to the loneliness content condition) online and complete questionnaires assessing changes in various outcomes over time.",[28,119,118],[28,119,118,631,632,633,634,635],"Internet-delivered cognitive behavioral therapy","Randomized controlled trial","Personalized therapy","Therapist assistance","Mental health system","2026-04-28",{"date":609,"type":40},{"date":639,"type":40},"2025-06-18",{"date":615,"type":21},{"name":642,"class":47},"University of Regina",{"id":644,"slug":645,"hasResults":12,"nctId":646,"briefTitle":647,"officialTitle":648,"acronym":649,"eligibilityCriteria":650,"healthyVolunteers":57,"sex":17,"minAge":227,"maxAge":4,"enrollmentInfo":651,"targetDuration":4,"studyType":22,"phases":653,"briefSummary":654,"conditions":655,"keywords":668,"overallStatus":134,"whyStopped":4,"lastUpdateSubmitDate":674,"lastUpdatePostDateStruct":675,"startDateStruct":677,"completionDateStruct":678,"leadSponsor":680,"locationsCount":4},"100619558","communityrx-dementia--peer-navigation-crxdpeer-100619558","NCT07346183","CommunityRx-Dementia + Peer Navigation (CRxDpeer)","CommunityRx-Dementia + Peer Navigation (CRxDpeer): A Real-World Implementation and Effectiveness Study of an IT-Based Social Care Intervention","CRxDpeer","Inclusion Criteria:\n\n* Self-identifies as a caregiver of a home-dwelling person with Alzheimer's disease or related dementias (ADRD)\n* Resides in the target geographic region of the study\n* Has access to a cell phone and agrees to receive text messages from the study\n* Has an email address that they can receive emails from\n* Individuals under the age of 18 who are emancipated minors in the state of Illinois and a caregiver of a person with dementia\n\nExclusion Criteria:\n\n* Minors who are not emancipated in the state of Illinois.\n* Previously participated in the intervention arm of the CommunityRx-Dementia clinical trial",{"count":652,"type":21},330,[24],"The CRxDpeer intervention, delivered by a trained peer navigator, in practice called a \"peer mentor\", includes three evidence-based components: (a) focused education about common social (e.g., food and housing insecurity) and caregiving (e.g., respite and end of life care) needs, (b) activation of personalized community resource information for social and caregiving needs through delivery of a resource list (HealtheRx) at the baseline encounter and coaching on how to communicate with service providers, coordinate services and manage social support (e.g., connect with their peer navigator, reach out to friends or relatives for support, identify support groups, etc.) and (c) ongoing navigation-focused support meant to boost the baseline intervention, including a series of proactive text messages over 12 months. During this time, the subject can respond to and communicate with the peer navigator for ongoing support.",[656,657,658,28,659,660,661,662,663,118,120,119,664,665,666,667],"Alzheimer s Disease","Dementia","Caregiver","Health-Related Social Needs","Social Care","Healthcare Utilization","End of Life Care","Caregiver Burden","Self-Efficacy","Peer Support","Implementation Science","Advance Care Planning",[669,670,671,672,673],"resource navigation","peer navigator","peer mentor","social care","dementia caregiver","2026-04-06",{"date":676,"type":40},"2026-04-07",{"date":71,"type":21},{"date":679,"type":21},"2029-02-28",{"name":681,"class":47},"University of Chicago",{"id":683,"slug":684,"hasResults":12,"nctId":685,"briefTitle":686,"officialTitle":686,"acronym":4,"eligibilityCriteria":687,"healthyVolunteers":12,"sex":17,"minAge":598,"maxAge":4,"enrollmentInfo":688,"targetDuration":4,"studyType":22,"phases":689,"briefSummary":690,"conditions":691,"keywords":693,"overallStatus":134,"whyStopped":4,"lastUpdateSubmitDate":698,"lastUpdatePostDateStruct":699,"startDateStruct":701,"completionDateStruct":703,"leadSponsor":705,"locationsCount":48},"100630971","the-role-of-solo-music-listening-in-reducing-loneliness-and-increasing-social-connectedness-in-older-adults-100630971","NCT07494604","The Role of Solo Music Listening in Reducing Loneliness and Increasing Social Connectedness in Older Adults","Inclusion Criteria:\n\n* Over the age of 70\n* Access to internet\n\nExclusion Criteria:\n\n* Cognitive Impairment\n* Self-reported hearing loss",{"count":20,"type":21},[24],"Loneliness has become an increasingly prevalent concern among older adults. A number of adverse physical and mental health outcomes may result from loneliness in this age group including cognitive decline and depression. These outcomes may lead to a higher strain on healthcare systems. Finding accessible and cost-effective strategies for reducing loneliness and increasing feelings of social connectedness is important for the well-being of older adults. Solo music listening is commonly used to regulate emotions and to promote well-being. While some preliminary evidence suggests that these benefits may extend to loneliness, research has not been clear on the functions or qualities of music that are most effective for older adults. This research project will consist of two parts. In Part 1, an interview will be conducted with older adults to determine what functions of music are most often used and most beneficial when their goal is to reduce loneliness. Part 2 will consist of a between-subjects experiment with four conditions. The top three characteristics obtained from Part 1 will represent the three music conditions, and the fourth condition will be a pink-noise control. Prior to the experiment, participants will self-select three pieces from each of the three music conditions. After selecting their music, they will be randomly assigned to either a music or pink-noise condition. Participants in the three music conditions will listen to the three self-selected pieces that adhere to their assigned condition. Loneliness and social connection outcomes will be assessed before and after listening using a Visual Analogue Scale (VAS). Potential moderators will be assessed after listening, which include nostalgia, absorption in music, and music reward. The results of this project will clarify whether psychological benefits of decreased loneliness and increased social connectedness can be found through music listening to enhance well-being, and whether singing along provides additional benefits. These findings may also be useful in developing future music-based interventions for reducing loneliness.",[28,438,692],"Music Listening Intervention",[694,187,695,280,696,697],"music","social conectedness","aging","music listening","2026-03-20",{"date":700,"type":40},"2026-03-27",{"date":702,"type":21},"2026-03-15",{"date":704,"type":21},"2027-12-20",{"name":706,"class":47},"Toronto Metropolitan University"]