[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"low-back-pain\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:low-back-pain":29},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,199,0,25,[9,43,80,104,135,162,191,217,240,268,296,322,353,375,397,421,457,486,515,536,563,588,616,639,670],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":16,"eligibilityCriteria":17,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100643141","phase-2-a-chronic-pain-master-protocol-cpmp-a-study-of-ly4065967-in-participants-with-chronic-low-back-pain-100643141",false,"NCT07641504","A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Chronic Low Back Pain","Randomized, Placebo-Controlled, Phase 2 Clinical Trial to Evaluate LY4065967 for the Treatment of Chronic Low Back Pain","BP07","Inclusion Criteria:\n\n* Have a history of low back pain for at least 3 months located between the 12th thoracic vertebra and the lower gluteal folds, with or without radiation\n* Have a body mass index at screening of ≤40 kilograms per meter squared (kg\u002Fm²).\n* Have stable glycemic control as indicated by a glycated hemoglobin (HbA1c) less than or equal to 10 at time of screening\n\nExclusion Criteria:\n\n* Are pregnant or breastfeeding\n* Have used a therapeutic injection to the spine in the 3 months prior to screening\n* Are using a spinal cord stimulator or dorsal root ganglion stimulator\n* Have ongoing complex regional pain syndrome or other concurrent medical conditions that could interfere with the evaluation of CLBP\n* Have a history of major spinal deformity, such as spondylolisthesis, spondylolysis, scoliosis, or spina bifida, that causes instability to the spine\n* Have an abnormal blood pressure (BP) systolic BP is greater than 140 millimeters mercury (\\>140 mm Hg) and diastolic BP\\>90 mm Hg at screening • Have history or current clinically significant cardiac disease, including arrhythmia, aortic aneurysm, heart failure, current electrolyte abnormalities, or any other conditions that could predispose to arrhythmia in the judgement of the investigator","ALL","18 Years",{"count":21,"type":22},150,"ESTIMATED","INTERVENTIONAL",[25],"PHASE2","The main purpose of this study is to test the safety and efficacy of study drug for the treatment of chronic low back pain (CLBP). This trial is part of the chronic pain master protocol H0P-MC-CPMP (NCT05986292), which is a protocol to accelerate the development of new treatments for chronic pain.",[28,29],"Chronic Pain","Low Back Pain","RECRUITING","2026-08-20",{"date":33,"type":34},"2026-08-21","ACTUAL",{"date":36,"type":34},"2026-08-12",{"date":38,"type":22},"2027-04",{"name":40,"class":41},"Eli Lilly and Company","INDUSTRY",37,{"id":44,"slug":45,"hasResults":12,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":23,"phases":52,"briefSummary":54,"conditions":55,"keywords":57,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":79},"100652389","virtual-tai-chi-for-chronic-low-back-pain-spine-2027-100652389","NCT07772154","Virtual Tai Chi for Chronic Low Back Pain (Spine 2027)","A Pragmatic Randomized Controlled Trial of Virtual Tai Chi for Chronic Low Back Pain: Effects on Disability, Pain, Quality of Life, and Healthcare Costs","Inclusion Criteria:\n\n* Age 18 years or older\n* Current non-specific low back pain lasting 12 weeks or more, with average pain over the past 7 days rated 4 or higher on a 0 to 10 scale\n* Understands written and spoken English\n* Has consistent internet access and is able to participate in virtual sessions\n* Agrees to appear on video during tai chi sessions, visible to the instructor and other participants\n* Willing to participate in a 12-month study including a 3-month foundation training phase with two 60-minute virtual live tai chi classes per week, 10 minutes of daily home practice, monthly 60-minute booster sessions during months 4 through 12, and five online surveys over 12 months at months 0, 2, 3, 6, and 12\n* Willing and able to provide informed consent\n\nExclusion Criteria:\n\n* Currently pregnant\n* Regular tai chi or qigong practice or research study participation in the past 5 years\n* History of spine surgery within the past 6 months\n* Severe psychiatric or medical comorbidities that, in the principal investigator's judgment, would make participation unsafe or not feasible\n\nNote on the second exclusion bullet: the protocol wording leaves open whether \"research study participation\" means participation in any research study or only in tai chi or qigong research. That wording has been carried over exactly as approved rather than clarified here, because the registry record should match the protocol. If the ambiguity is worth resolving, it belongs in a future amendment and then in a record update, not in this response.",{"count":51,"type":22},600,[53],"NA","This study tests whether a virtually delivered integrated tai chi, qigong, and meditation program, added to usual care, improves chronic low back pain, disability, quality of life, and healthcare costs compared with usual care alone. Adults with chronic low back pain are randomized to begin the program immediately (Tai Chi Now) or after a six-month period (Tai Chi Later). Outcomes are collected by online survey over twelve months.",[29,56],"Chronic Low-back Pain (cLBP)",[58,59,60,61,62,63,64,65,66,67],"tai chi","qigong","meditation","mind-body","virtual care","telehealth","disability","quality of life","cost-effectiveness","non-pharmacologic","NOT_YET_RECRUITING","2026-08-17",{"date":71,"type":34},"2026-08-19",{"date":73,"type":22},"2026-10-01",{"date":75,"type":22},"2028-02-15",{"name":77,"class":78},"New York Medical College","OTHER",1,{"id":81,"slug":82,"hasResults":12,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":4,"eligibilityCriteria":86,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":87,"enrollmentInfo":88,"targetDuration":4,"studyType":23,"phases":90,"briefSummary":91,"conditions":92,"keywords":94,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":79},"100651478","core-endurance-versus-segmental-stabilization-exercise-in-recreational-athletes-with-low-back-pain-100651478","NCT07760103","Core Endurance Versus Segmental Stabilization Exercise in Recreational Athletes With Low Back Pain","Comparison of the Effects of Core Endurance Exercises and Segmental Stabilization Exercises on Low Back Pain and Core Endurance in Recreational Athletes With Non-Specific Low Back Pain: A Randomized Trial","Inclusion Criteria:\n\n* Aged 18 years or older\n* Recreational athlete who has recently begun regular physical activity\n* Diagnosis of non-specific low back pain confirmed by an orthopaedic specialist\n* Two or more episodes of low back pain within the past year\n* Not participating in any other treatment program during the study period\n\nExclusion Criteria:\n\n* Radicular (nerve root) signs\n* Underlying systemic or visceral disease\n* Diagnosis of ankylosing spondylitis\n* Spinal pathology such as spondylolysis or spondylolisthesis\n* Previous lumbar spine surgery\n* History of vestibular dysfunction\n* Lower extremity injury within the past month\n* History of traumatic concussion within the past three months","45 Years",{"count":89,"type":22},60,[53],"Low back pain is a common musculoskeletal complaint among athletes, and most cases are classified as non-specific low back pain, in which no clear anatomical or pathological source of pain can be identified. Recreational athletes, who exercise regularly for health and fitness rather than for competition, often have less structured training planning and technical supervision than professional athletes, which may increase their susceptibility to musculoskeletal complaints. Core stability has become an important consideration in the prevention and management of low back pain. The core region includes the abdominal muscles, paraspinal muscles, diaphragm, and pelvic floor muscles, and plays an important role in maintaining spinal stability. Reduced activation and endurance of these muscles may increase the load on the lumbar spine and contribute to the development of low back pain. This randomized trial compares two exercise approaches in recreational athletes with non-specific low back pain: a core endurance exercise program and a segmental stabilization exercise program targeting the transversus abdominis and lumbar multifidus. Participants are randomly assigned to one of the two programs, both delivered three days per week for six weeks under physiotherapist supervision. Pain and functional status, dynamic balance, and core muscle endurance are assessed before the program and at the end of the six-week program.",[29,93],"Athletic Injuries",[95],"core endurance",{"date":97,"type":34},"2026-08-18",{"date":99,"type":34},"2026-08-15",{"date":101,"type":22},"2026-12-30",{"name":103,"class":78},"Uskudar University",{"id":105,"slug":106,"hasResults":12,"nctId":107,"briefTitle":108,"officialTitle":109,"acronym":110,"eligibilityCriteria":111,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":112,"targetDuration":4,"studyType":23,"phases":114,"briefSummary":115,"conditions":116,"keywords":118,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":127,"startDateStruct":129,"completionDateStruct":131,"leadSponsor":133,"locationsCount":79},"100622062","back-to-life---early-rehabilitation-therapy-for-patients-undergoing-lumbar-spinal-fusion---a-single-case-experimental-study-100622062","NCT07378735","Back to Life - Early Rehabilitation Therapy for Patients Undergoing Lumbar Spinal Fusion","Back to Life - Early Rehabilitation Therapy for Patients Undergoing Lumbar Spinal Fusion Surgery - A Single-case Experimental Design Study","Back to Life","The investigators will in total include 12 patients undergoing an LSF from the Centre for Rheumatology and Spine Diseases at Rigshospitalet, Denmark.\n\nBefore inclusion, a pilot of three participants will be performed.\n\nInclusion Criteria for all included:\n\n* ≥ 18 years of age\n* Low back pain (LBP) \\> 3 months\n* Read and understand the Danish language\n* The participants should be a part of Frederiksberg Municipality and Copenhagen Municipality (in Denmark)\n\nExclusion Criteria:\n\n* Post-traumatic vertebral compression\u002Fdeformity\n* Patients with the following conditions (infection, neoplasm, metastasis, metabolic bone disease, fractures or other known autoimmune arthropathies)\n* Patients with patient-related circumstances (physical or mental status) that impede their ability to give informed consent and adhere to the study program (e.g., dementia, developmental disorders, or substance-induced cognitive impairment)\n* Other special conditions, where the patient is judged by the surgeon as inappropriate to participate",{"count":113,"type":22},12,[53],"Aim This study aims to assess the effectiveness of an early intervention comprising individually tailored physiotherapy, including dialogue, education, and graded activity, following lumbar spinal fusion surgery. The effectiveness will be evaluated on patient-specific goals, physical activity, pain intensity, pain interference, fear of movement, and pain self-efficacy for patients after a lumbar spinal fusion.",[29,117],"Lumbar Spinal Fusion",[119,120,121,122,123,124,125,126],"Physical activity","Low back pain","Lumbar spinal fusion","Exercise","Rehabilitation","Physiotherapy","Single-case experimental study","Cognitive behavioural approach",{"date":128,"type":34},"2026-08-14",{"date":130,"type":34},"2026-06-01",{"date":132,"type":22},"2028-11",{"name":134,"class":78},"Rigshospitalet, Denmark",{"id":136,"slug":137,"hasResults":12,"nctId":138,"briefTitle":139,"officialTitle":140,"acronym":141,"eligibilityCriteria":142,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":143,"targetDuration":4,"studyType":23,"phases":145,"briefSummary":146,"conditions":147,"keywords":149,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":155,"startDateStruct":156,"completionDateStruct":158,"leadSponsor":160,"locationsCount":79},"100615265","stratified-targeted-engagement-from-primary-care-to-physical-therapy-steppt-100615265","NCT07290361","Stratified Targeted Engagement From Primary Care to Physical Therapy (STEPPT)","Stratified Targeted Engagement From Primary Care to Physical Therapy (STEPPT): A Pragmatic Stepped Wedge Cluster Randomized Trial","STEPPT","Inclusion Criteria\n\n* 18 years or older.\n* Identify as either Hispanic or Non-Hispanic ethnicity, inclusive of all races.\n* Seeking care for spine pain at an Adult or Adult Walk-in primary care clinic within the participating Federally Qualified Health Center (FQHC).\n* New or existing spine pain problem: A new spine pain problem is defined by a new ICD code for neck or back pain added to the problem list during a visit with a primary care physician. An existing spine pain problem is defined by an existing ICD code for neck or back pain on the problem list that is associated with a physician referral for any service during the visit related to the neck or back pain problem.\n* Signed a broad consent for the use of de-identified health information for research at the participating FQHC.\n\nExclusion Criteria:\n\n* Spine pain associated with a non-musculoskeletal etiology (e.g., infection, cancer, urological disorders, pregnancy, etc.)\n* Patients requiring urgent medical intervention (e.g., fracture, cauda equina syndrome, etc)\n* Active physical therapy referral for spine pain at the time of the index encounter.\n* Previously referred to physical therapy through the STEPPT Care Pathway.\n* Physical therapy referrals external to the FQHC will be excluded from the analysis of physical therapy adherence",{"count":144,"type":22},17587,[53],"The goal of this clinical trial is to learn if a health system intervention called \"Stratified Targeted Engagement from Primary Care to Physical Therapy (STEPPT)\" can improve how often doctors refer Hispanic patients with spine pain to physical therapy (referral rate) and how often patients attend physical therapy after being referred (adherence rate). The main questions this study aims to answer are 1) does STEPPT improve physical therapy referral and adherence rates compared to usual care for Hispanic patients with spine pain who seek care in a Federally Qualified Health Center (FQHC) serving low income communities, and 2) how consistently do FQHC providers and staff deliver STEPPT to patients who may benefit? STEPPT will train doctors and other health care providers to educate participants on the benefits of physical therapy for spine pain and participants will receive culturally tailored handouts and videos to teach them about their spine pain and what to expect in physical therapy. Patients will also receive personalized assistance to schedule their physical therapy appointment and address potential barriers for attending the appointment.",[29,148],"Neck Pain",[150,123,151,152,153,154],"Physical therapy","Hispanic","Heatlh Services","Healthcare utilization","Federally Qualified Health Center",{"date":128,"type":34},{"date":157,"type":34},"2025-12-01",{"date":159,"type":22},"2029-02-28",{"name":161,"class":78},"San Diego State University",{"id":163,"slug":164,"hasResults":12,"nctId":165,"briefTitle":166,"officialTitle":167,"acronym":168,"eligibilityCriteria":169,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":170,"targetDuration":4,"studyType":23,"phases":172,"briefSummary":173,"conditions":174,"keywords":180,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":184,"startDateStruct":185,"completionDateStruct":187,"leadSponsor":189,"locationsCount":79},"100591740","digitally-delivered-treatments-to-reduce-chronic-low-back-pain-100591740","NCT06984354","Digitally Delivered Treatments to Reduce Chronic Low Back Pain","NOTUS Trial: A Randomised Controlled Trial of Two Digitally Delivered Treatment Options for Chronic Back Pain","NOTUS","Inclusion Criteria:\n\n* Experiencing non-specific chronic low back pain (LBP), defined as pain between the 12th rib and the buttock crease.\n* LBP with or without leg pain (in case of leg pain, LBP is worse than leg pain).\n* Currently consulting with a general practitioner for their non-specific chronic LBP across Australia.\n* Mean pain intensity score on the Numeric Rating Scale ≥ 3\u002F10 in the past week.\n* A score of at least moderate on question 8 of the physical functioning component of the SF-36 questionnaire.\n* Access to a mobile device with minimal requirements to download the study app (300MB).\n* An internet connection to access the mobile app functionalities.\n* Able to understand English via reading and audio materials.\n\nExclusion Criteria:\n\n* Known or suspected specific spinal (e.g., radiculopathy, fracture) or specific non-spinal non- (e.g., tumour, infection) pathology.\n* Less than six months post-spinal surgery.\n* Scheduled for major surgery during the program or the follow-up period.\n* Known or suspected serious psychiatric condition not being treated by a health professional that would impact adherence to the trial activities.\n* Known or suspected sight or hearing problems that would limit access to the intervention components (reading and listening using headphones).",{"count":171,"type":22},720,[53],"This study aims to evaluate the effectiveness of pain education and clinical hypnosis delivered via a mobile app compared to a guideline-informed factsheet for reducing pain and disability in people experiencing chronic low back pain attending general practice.",[29,175,176,177,178,179],"Chronic Pain (Back \u002F Neck)","General Practice (GP), Primary Care Settings","Digital Health","Hypnosis, Chronic Pain Management","Patient Education",[181,177,182,183,28],"Back Pain","Hypnosis","Pain Education",{"date":128,"type":34},{"date":186,"type":34},"2025-06-02",{"date":188,"type":22},"2028-05-26",{"name":190,"class":78},"Neuroscience Research Australia",{"id":192,"slug":193,"hasResults":12,"nctId":194,"briefTitle":195,"officialTitle":196,"acronym":4,"eligibilityCriteria":197,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":198,"enrollmentInfo":199,"targetDuration":4,"studyType":23,"phases":201,"briefSummary":202,"conditions":203,"keywords":204,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":210,"lastUpdatePostDateStruct":211,"startDateStruct":212,"completionDateStruct":213,"leadSponsor":215,"locationsCount":4},"100651820","acceptance-and-commitment-therapy-plus-physiotherapy-for-chronic-low-back-pain-100651820","NCT07766616","Acceptance and Commitment Therapy Plus Physiotherapy for Chronic Low Back Pain","Effects of Adding Acceptance and Commitment Therapy to Physiotherapy Program on Pain Catastrophizing, Stress, Disability, and Sleep Quality in Individuals With Chronic Low Back Pain","Inclusion Criteria:\n\nA\\_Aged between 18-55 years. B\\_Clinically diagnosed with non-specific chronic low back pain (CLBP). C\\_Low back pain persisting for more than 3 months.\n\nExclusion Criteria:\n\nA. History of previous spinal surgeries or invasive interventions in the lumbar region.\n\nB. Presence of \"Red Flags\" or serious underlying pathologies, such as spinal tumors, infections, or vertebral fractures.\n\nC. Current or recent (within the last 6 months) participation in structured psychological rehabilitation or behavioral therapy programs.\n\nD. Clinical evidence of neurological deficits, radiculopathy, or cauda equina syndrome.\n\nE. Pregnancy, due to the physiological changes affecting musculoskeletal mechanics.\n\nF. Severe behavioral or communication impairments preclude the ability to follow the intervention protocol or complete the self-report assessments.\n\nG. Patients who take any sleep medication or for mental health medication. H. Patients who have done physiotherapy program last 3 months.","55 Years",{"count":200,"type":22},64,[53],"This study is a randomized controlled trial (RCT) investigating whether adding Acceptance and Commitment Therapy (ACT) to standard physiotherapy provides greater benefits for adults with chronic low back pain than physiotherapy alone.\n\nA total of 60 participants will be randomly allocated into two groups: ACT plus physiotherapy and physiotherapy alone. Both groups will receive a 8-weeks program with two sessions per week. The ACT component focuses on acceptance, psychological flexibility, mindfulness, cognitive defusion, values, and committed action.\n\nThe main outcomes are pain catastrophizing, functional disability, perceived stress, and sleep quality, assessed using the PCS, ODI, PSS, and PSQI. The study aims to determine whether combining psychological and physical rehabilitation produces better outcomes than physiotherapy alone.",[29],[205,206,207,208,209],"low back pain","sleep","Acceptance and Commitment Therapy","Exercises","Randomization","2026-08-11",{"date":128,"type":34},{"date":31,"type":22},{"date":214,"type":22},"2027-02-01",{"name":216,"class":78},"Al-Azhar University",{"id":218,"slug":219,"hasResults":12,"nctId":220,"briefTitle":221,"officialTitle":222,"acronym":4,"eligibilityCriteria":223,"healthyVolunteers":12,"sex":18,"minAge":4,"maxAge":4,"enrollmentInfo":224,"targetDuration":4,"studyType":23,"phases":226,"briefSummary":227,"conditions":228,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":210,"lastUpdatePostDateStruct":232,"startDateStruct":234,"completionDateStruct":236,"leadSponsor":238,"locationsCount":79},"100651632","how-patient-education-helps-patients-with-chronic-musculoskeletal-disorders-stick-to-home-exercise-for-pain-relief-100651632","NCT07764354","How Patient Education Helps Patients With Chronic Musculoskeletal Disorders Stick to Home Exercise for Pain Relief.","Impact of Patient Education on Adherence to Therapeutic Exercise in Chronic Musculoskeletal Disorders: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Chronic low back pain patients (more than three months)\n* Knee osteoarthritis\n* Patients with partial Rotator cuff tear\n\nExclusion Criteria:\n\n* Acute injuries\n* Systemic inflammatory conditions\n* Neurological deficits affecting exercise\n* Cognitive impairment preventing understanding of education materials\n* Participation in other rehabilitation programs",{"count":225,"type":22},120,[53],"The study aims to evaluate the effectiveness of a structured patient education program in enhancing adherence to prescribed home exercise regimens in individuals with chronic low back pain, knee osteoarthritis, and shoulder pain.",[29,229,230,231],"Knee Arthritis Osteoarthritis","Shoulder Disease","Shoulder and Upper Arm Injury",{"date":233,"type":34},"2026-08-13",{"date":235,"type":34},"2026-04-12",{"date":237,"type":22},"2027-06-30",{"name":239,"class":78},"Imam Abdulrahman Bin Faisal University",{"id":241,"slug":242,"hasResults":12,"nctId":243,"briefTitle":244,"officialTitle":245,"acronym":246,"eligibilityCriteria":247,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":248,"targetDuration":4,"studyType":23,"phases":250,"briefSummary":251,"conditions":252,"keywords":257,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":259,"lastUpdatePostDateStruct":260,"startDateStruct":261,"completionDateStruct":263,"leadSponsor":265,"locationsCount":267},"100607611","managing-pain-using-optimized-sequences-by-adjusting-parameters-with-independent-current-control-100607611","NCT07190807","Managing Pain Using Optimized Sequences by Adjusting Parameters With Independent Current Control","Managing Pain Using Optimized Sequences by Adjusting Parameters With Independent Current Control (MOSAIC Study)","MOSAIC","Key Inclusion Criteria:\n\n* Persistent spinal pain syndrome (PSPS) Type I (or non-surgical refractory back pain), or PSPS Type II (Failed Back Surgery Syndrome, FBSS) diagnosis.\n* Diagnosed with chronic pain of the trunk and\u002For limbs for at least 6 months.\n* 18 years of age or older when written informed consent is obtained\n* Able to independently read and complete all questionnaires and assessments provided in English.\n* Signed a valid, IRB or EC approved informed consent form (ICF) provided in English.\n\nKey Exclusion Criteria:\n\n* Any pain-related diagnosis, medical or psychological condition that, in the Investigator's judgment might confound reporting of study outcomes (e.g., vascular or neurogenic claudication, osteoarthritis, plantar fasciitis, pelvic pain, anginal pain, chronic migraine, acute herniated disc, malignancy, untreated major depression, injury claim).\n* Significant cognitive impairment at Screening and Baseline visit that, in the opinion of the Investigator, would reasonably be expected to impair the study candidate's ability to participate in the study\n* A female who is pregnant, lactating, or is of childbearing potential and planning to get pregnant during the study or not using adequate contraception.\n* Participating (or intends to participate) in another drug or device clinical trial that may influence the data that will be collected for this study.",{"count":249,"type":22},70,[53],"Study to evaluate the effectiveness of time variant pulse (TVP)-SCS in patients with chronic pain using commercially approved Boston Scientific SCS Systems per local Instructions for use (IFU).\n\nIn addition, to compile real-world clinical outcomes in subjects with chronic, intractable low back and\u002For leg pain.",[28,253,29,254,255,256],"Intractable Pain","Chronic Low-back Pain","Chronic Leg Pain","Leg Pain",[258],"Spinal Cord Stimulation","2026-08-10",{"date":210,"type":34},{"date":262,"type":34},"2025-11-07",{"date":264,"type":22},"2029-05",{"name":266,"class":41},"Boston Scientific Corporation",7,{"id":269,"slug":270,"hasResults":12,"nctId":271,"briefTitle":272,"officialTitle":273,"acronym":4,"eligibilityCriteria":274,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":275,"enrollmentInfo":276,"targetDuration":4,"studyType":23,"phases":278,"briefSummary":279,"conditions":280,"keywords":281,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":288,"lastUpdatePostDateStruct":289,"startDateStruct":290,"completionDateStruct":292,"leadSponsor":294,"locationsCount":4},"100651470","dual-task-neuromuscular-warm-up-exercises-in-chronic-low-back-pain-100651470","NCT07761247","Dual-Task Neuromuscular Warm-Up Exercises in Chronic Low Back Pain","Immediate Effects of Dual-Task Neuromuscular Warm-Up Exercises on Balance and Proprioception in Individuals With Chronic Nonspecific Low Back Pain: A Randomized Controlled Study","Inclusion Criteria:\n\n* Diagnosed with nonspecific low back pain persisting for at least 3 months.\n* Pain intensity of ≥3 on the Visual Analog Scale (VAS).\n* Sufficient cognitive ability to understand and follow verbal and written instructions in Turkish.\n* Independent mobility sufficient to perform the tests and exercises.\n* Willingness to participate and provision of written informed consent.\n\nExclusion Criteria:\n\n* Acute disc herniation, spinal stenosis, spondylolysis, or spondylolisthesis.\n* Previous spinal surgery or a history of severe trauma affecting the spine.\n* Rheumatic diseases, malignancy, infection, or neurological diseases that may cause low back pain.\n* Sensory or motor loss in the lower extremities or deep tendon reflex loss indicating radiculopathy.\n* Known vestibular or visual system disorders.\n* Body mass index (BMI) ≥30 kg\u002Fm².\n* Pregnancy.\n* Physiotherapy\u002Frehabilitation treatment or steroid injection targeting the lumbar region within the previous 3 months.\n* Use of analgesics, muscle relaxants, or sedatives within the previous 24 hours that may affect balance or pain threshold.\n* Other orthopedic or systemic health conditions that may interfere with exercise or balance testing.","50 Years",{"count":277,"type":22},40,[53],"This study aims to investigate the immediate effects of dual-task neuromuscular warm-up exercises on balance and proprioception in individuals with chronic nonspecific low back pain. Participants will be randomly assigned to either a dual-task neuromuscular warm-up exercise group or a neuromuscular warm-up exercise group. Both groups will also receive the same conventional physiotherapy program. Balance, proprioception, lumbar muscle properties, pressure pain threshold, and flexibility will be assessed before and after the intervention to determine whether adding cognitive tasks to neuromuscular warm-up exercises provides additional immediate benefits.",[29],[282,283,284,285,286,287],"Chronic Nonspecific Low Back Pain","Dual-Task Training","Neuromuscular Warm-Up","Balance","Proprioception","Postural Control","2026-08-08",{"date":36,"type":34},{"date":291,"type":22},"2026-08-25",{"date":293,"type":22},"2027-03-10",{"name":295,"class":78},"Istinye University",{"id":297,"slug":298,"hasResults":12,"nctId":299,"briefTitle":300,"officialTitle":300,"acronym":4,"eligibilityCriteria":301,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":302,"enrollmentInfo":303,"targetDuration":4,"studyType":23,"phases":305,"briefSummary":306,"conditions":307,"keywords":310,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":314,"lastUpdatePostDateStruct":315,"startDateStruct":316,"completionDateStruct":318,"leadSponsor":320,"locationsCount":79},"100482044","therapeutic-mechanisms-of-epidural-spinal-cord-stimulation-100482044","NCT05556902","Therapeutic Mechanisms of Epidural Spinal Cord Stimulation","Inclusion Criteria:\n\n1. Male or Female, age 18-89\n2. Chronic pain for more than 3 months\n3. Willing to visit a research lab\n4. Willing to undergo a blood draw\n5. Able to provide written informed consent\n\nExclusion Criteria\n\n1. History of neurological disease (e.g., dementias, Parkinson's)\n2. History of stroke\n3. Current diagnosis of cancer\n4. Subject is unwilling or unable to comply with the protocol","89 Years",{"count":304,"type":22},80,[53],"The purpose of this study in patients undergoing routine care epidural spinal cord stimulation (SCS) is to determine 1) whether SCS reduces arterial blood pressure (BP) in patients which chronic low back pain and hypertension, 2) whether higher baseline BP (i.e., hypertension) predicts reductions in pain following SCS, and finally 3) whether different SCS waveforms elicits stimulus-evoked compound action potentials (ECAPs) in spinal cord and at the cortex (electroencephalography, and magnetoenchphalography).",[308,29,309],"Blood Pressure","Hypertension",[258,311,312,313],"Epidural Spinal Cord Stimulation","SCS","Arterial Blood Pressure","2026-08-06",{"date":210,"type":34},{"date":317,"type":34},"2022-08-02",{"date":319,"type":22},"2030-05-01",{"name":321,"class":78},"University of Alabama at Birmingham",{"id":323,"slug":324,"hasResults":12,"nctId":325,"briefTitle":326,"officialTitle":327,"acronym":328,"eligibilityCriteria":329,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":87,"enrollmentInfo":330,"targetDuration":4,"studyType":23,"phases":332,"briefSummary":333,"conditions":334,"keywords":336,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":344,"lastUpdatePostDateStruct":345,"startDateStruct":347,"completionDateStruct":349,"leadSponsor":351,"locationsCount":79},"100650513","efficacy-of-artificial-intelligence-driven-program-versus-traditional-physical-therapy-program-in-patients-with-low-back-dysfunction-100650513","NCT07749833","EFFICACY OF ARTIFICIAL INTELLIGENCE DRIVEN PROGRAM VERSUS TRADITIONAL PHYSICAL THERAPY PROGRAM IN PATIENTS WITH LOW BACK DYSFUNCTION","Efficacy of an Artificial Intelligence-Driven Program Versus a Traditional Physical Therapy Program in Patients With Low Back Dysfunction","AI-LBD","Inclusion Criteria:\n\n* Adults aged 18-45 years.\n* Male or female participants.\n* Clinical diagnosis of low back dysfunction by a physiotherapist or physician.\n* Symptoms lasting more than 3 months.\n* Ability to participate in physical therapy or use AI-based rehabilitation tools.\n* Willingness to comply with the study protocol and provide written informed consent.\n\nExclusion Criteria:\n\n* Recent spinal injury or spinal surgery.\n* Previous spinal surgery within the last 6 months.\n* Severe neurological disorders (e.g., multiple sclerosis or Parkinson's disease).\n* Chronic conditions that significantly limit mobility (e.g., advanced arthritis).\n* Current use of strong opioid analgesics.\n* Severe psychiatric disorders.\n* Inability to use or access the required technology for the AI intervention.",{"count":331,"type":22},68,[53],"Low back dysfunction is one of the most common musculoskeletal disorders and is associated with pain, disability, and reduced quality of life. Artificial intelligence (AI) has emerged as a promising tool to support personalized rehabilitation by improving exercise prescription, monitoring adherence, and providing real-time feedback. This randomized controlled trial aims to compare the effectiveness of an AI-driven rehabilitation program with a traditional physical therapy program in patients with low back dysfunction. Primary outcomes include pain intensity, functional disability, and quality of life. The findings may provide evidence regarding the role of AI-assisted rehabilitation in improving clinical outcomes.",[29,335],"Low Back Dysfunction",[337,335,29,338,123,339,340,341,342,343],"Artificial Intelligence","Physical Therapy","Exercise Therapy","AI-Driven Rehabilitation","Musculoskeletal Rehabilitation","Randomized Controlled Trial","Personalized Rehabilitation","2026-08-05",{"date":346,"type":34},"2026-08-07",{"date":348,"type":22},"2026-08",{"date":350,"type":22},"2027-01",{"name":352,"class":78},"Cairo University",{"id":354,"slug":355,"hasResults":12,"nctId":356,"briefTitle":357,"officialTitle":358,"acronym":4,"eligibilityCriteria":359,"healthyVolunteers":360,"sex":18,"minAge":19,"maxAge":87,"enrollmentInfo":361,"targetDuration":4,"studyType":23,"phases":362,"briefSummary":363,"conditions":364,"keywords":4,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":366,"lastUpdatePostDateStruct":367,"startDateStruct":369,"completionDateStruct":371,"leadSponsor":373,"locationsCount":79},"100636643","brain-connectivity-and-perceptive-surfaces-in-chronic-low-back-pain-super-rmnf-100636643","NCT07568353","Brain Connectivity and Perceptive Surfaces in Chronic Low Back Pain (SUPER-RMNf)","Lombalgia Cronica Aspecifica e Superfici Percettive: Rappresentazione Corticale Del Tronco Nella Risposta al Trattamento Riabilitativo - Studio Quasi-sperimentale Non Randomizzato","Inclusion Criteria:\n\n* Aged between 18 and 45 years\n* Right-handed dominance\n* Good general health condition\n* Ability to provide written informed consent.\n\nFor the patient group:\n\n\\- Clinical diagnosis of non-specific chronic low back pain with a duration of more than 3 months\n\nFor the control group:\n\n\\- Healthy volunteers without a history of chronic pain\n\nExclusion Criteria:\n\n* Contraindications to 3T Magnetic Resonance Imaging, such as pacemakers or non-compatible metallic implants\n* Pregnancy or breastfeeding\n* Presence of significant neurological or psychiatric pathologies\n* Current use of psychoactive medications.\n* Sensory or motor disorders of the lower limbs that prevent interaction with the perceptive surface.\n* Unstable or acute clinical conditions.\n* Inability to remain still during the MRI scanning procedure",true,{"count":277,"type":22},[53],"Rationale:\n\nChronic Low Back Pain (CLBP) is often associated with \"cortical reorganization,\" where the brain's map of the back becomes less precise. This phenomenon contributes to the persistence of pain and reduced body awareness. While traditional rehabilitation focuses on the physical structure of the spine, neurocognitive approaches use \"perceptive surfaces\" to provide specific tactile and proprioceptive feedback, aiming to \"retrain\" the brain's representation of the trunk.\n\nObjective and Hypothesis:\n\nThe primary goal of this study is to investigate how the brain responds to stimulation from these perceptive surfaces in patients with CLBP compared to healthy individuals. The investigators hypothesize that using these surfaces will lead to immediate changes in functional brain connectivity, particularly in areas responsible for body awareness and pain processing (somatosensory and salience networks).\n\nStudy Procedures:\n\nThe study will involve 20 patients with chronic non-specific low back pain and 20 healthy volunteers. All participants will undergo a Functional Magnetic Resonance Imaging (fMRI) session. During the scan, participants will be placed on a specialized perceptive surface. Brain activity and connectivity will be measured at rest and during specific tactile stimulation. Additionally, advanced imaging techniques (SANDI model) will be used to look at the microscopic structure of brain cells (neurons).\n\nClinical Impact:\n\nBy comparing the two groups, the study aims to identify specific \"brain signatures\" of recovery. This could help clinical professionals understand if perceptive surfaces can effectively restore cortical maps, leading to better personalized rehabilitation strategies for chronic pain.",[29,365],"Healthy","2026-07-31",{"date":368,"type":34},"2026-08-04",{"date":370,"type":22},"2026-09-01",{"date":372,"type":22},"2027-03-01",{"name":374,"class":78},"G. d'Annunzio University",{"id":376,"slug":377,"hasResults":12,"nctId":378,"briefTitle":379,"officialTitle":379,"acronym":4,"eligibilityCriteria":380,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":381,"targetDuration":4,"studyType":23,"phases":382,"briefSummary":383,"conditions":384,"keywords":385,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":388,"lastUpdatePostDateStruct":389,"startDateStruct":391,"completionDateStruct":393,"leadSponsor":395,"locationsCount":79},"100650013","potential-of-virtual-reality-in-primary-chronic-low-back-pain-100650013","NCT07742111","Potential of Virtual Reality in Primary Chronic Low Back Pain","Inclusion Criteria:\n\n* Individuals with primary chronic low back pain aged ≥18 years, who present a moderate pain intensity (≥4 on the Numeric Pain Rating Scale) and a mild level of fear of movement.\n\nExclusion Criteria:\n\n* have a diagnosis of spondylolisthesis or lumbar spinal stenosis;\n* are experiencing an exacerbation of low back pain symptoms at the time of screening;\n* present with constant and widespread nonspecific pain;\n* are in an active phase of rheumatoid arthritis;\n* have a progressive neurological disease;\n* are currently pregnant or within 6 months postpartum;\n* have a diagnosed psychiatric disorder;\n* have a malignant disease;\n* have serious cardiac conditions;\n* have contraindications to physical exercise in general;",{"count":113,"type":22},[53],"This is a single-case experimental design study enrolling individuals with chronic low back pain who will be receiving pain science education and virtual reality over 3 weeks.",[29],[120,386,387],"Virtual reality","Pain science education","2026-07-28",{"date":390,"type":34},"2026-08-03",{"date":392,"type":34},"2026-05-01",{"date":394,"type":22},"2026-10-30",{"name":396,"class":78},"Aveiro University",{"id":398,"slug":399,"hasResults":12,"nctId":400,"briefTitle":401,"officialTitle":402,"acronym":4,"eligibilityCriteria":403,"healthyVolunteers":12,"sex":18,"minAge":404,"maxAge":275,"enrollmentInfo":405,"targetDuration":4,"studyType":23,"phases":407,"briefSummary":408,"conditions":409,"keywords":410,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":413,"lastUpdatePostDateStruct":414,"startDateStruct":415,"completionDateStruct":417,"leadSponsor":419,"locationsCount":79},"100649064","spray-and-stretch-technique-versus-strain-counter-strain-in-patients-with-non-specific-low-back-pain-100649064","NCT07729774","Spray and Stretch Technique Versus Strain Counter Strain in Patients With Non Specific Low Back Pain","Comparative Effect of Spray and Stretch Technique Versus Strain Counter Strain on Hamstring Muscles for Pain , Disability and Mobility in Patients With Non Specific Low Back Pain","Inclusion Criteria:\n\n* AGE(35 to 50)\n\n  * Gender (both male and female)\n  * Negative lasegue test\n  * Negative slump test\n  * Negative prone instability test\n\nExclusion Criteria:\n\n* Fracture or instability (4)\n\n  * History of cancer\n  * Inflammatory condition like ankylosing spondylitis\n  * Neurological deficits like cauda equina syndrome or motor weakness\n  * History of previous of previous lumber surgery\n  * Pregnancy\n  * Structural deformity like scoliosis\n  * Herniated disc\n  * Nerve compression\n  * Spinal stenosis","35 Years",{"count":406,"type":22},30,[53],"Non-specific low back pain refers to pain in the lower back region that cannot be attributed to a specific identifiable pathology such as infection, tumor, osteoporosis, lumbar disc herniation, spinal stenosis or fracture. It is the most common type of low back pain, accounting for about 85-90% of cases. Non specific low back pain is posteriorly occurring that is located between lower rib margin and gluteal fold. It is exacerbated by sustained back postures, back movements or back muscle imbalances. The aim of study is to find out which technique whether Spray and stretch technique or strain Counter strain works better in reducing pain ,improving movement ,and decreasing disability caused by tight hamstring muscles in people with non specific low Back Pain.",[29],[205,411,412],"strain counter strain technique","mobility","2026-07-27",{"date":388,"type":34},{"date":416,"type":34},"2026-06-20",{"date":418,"type":22},"2026-09-20",{"name":420,"class":78},"Riphah International University",{"id":422,"slug":423,"hasResults":12,"nctId":424,"briefTitle":425,"officialTitle":426,"acronym":427,"eligibilityCriteria":428,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":429,"targetDuration":4,"studyType":23,"phases":431,"briefSummary":432,"conditions":433,"keywords":444,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":413,"lastUpdatePostDateStruct":449,"startDateStruct":451,"completionDateStruct":453,"leadSponsor":455,"locationsCount":79},"100622663","biologic-injection-for-adults-with-lumbar-disc-herniation-100622663","NCT07386548","Biologic Injection For Adults With Lumbar Disc Herniation","Bone Marrow Aspirate Concentrate Injection With MRI's - A Prospective Randomized Control Trial","BMAC","Inclusion Criteria:\n\n* Male or female patients ≥ 18 years of age\n* Clinically and\u002For radiographically (MRI) confirmed diagnosis of degenerative disc disease of the lumbar spine, lumbar disc herniation, and indication for lumbar microdiscectomy surgery\n* Unresponsive to conservative\u002Fnon-operative treatment for \\>3 months\n* Psychosocial, mental and physical ability to understand and to adhere to this protocol, especially adhering to the visit schedule follow-ups and observe the treatment plan\n\nExclusion Criteria:\n\n* Prisoners\n* Individuals who are not yet adults (infants, children, teenagers)\n* Individuals who are not able to clearly understand English\n* Adults with diminished capacity to consent\n* Major cognitive impairment causing to inability to understand and provide informed consent\n* Active malignancy\n* Active chronic or acute infection\n* Autoimmune disorder that impacts the lumbar spine (ankylosing spondylitis, lupus e.g.)\n* Bone marrow-derived or non-bone marrow-derived cancer\n* Low platelet count or clotting disorders\n* Prior surgery at the level to be treated or the adjacent level",{"count":430,"type":22},90,[53],"The goal of this clinical trial is to find out whether adding a bone-marrow aspirate concentrate (BMAC) injection during surgery can improve recovery in adults undergoing lumbar microdiscectomy for a lumbar disc herniation.\n\nThe main questions it aims to answer are:\n\n* Does the BMAC injection lead to better disc tissue health after surgery (as seen on MRI scans)?\n* Does the BMAC injection lead to greater improvement in pain and disability compared to surgery alone?\n\nParticipants will be adults aged 18 and older who are scheduled for lumbar microdiscectomy surgery.\n\nResearchers will compare one group of participants receiving the standard-of-care surgery plus the BMAC injection with another group receiving the same surgery without the injection to see if the injection offers added benefit.\n\nParticipants will:\n\n* Have surgery (microdiscectomy) with or without the injection.\n* Complete pain and disability questionnaires at several times over 2 years.\n* Undergo MRI scans at baseline and follow-up to assess disc structure and tissue health.\n* Provide samples of leftover disc or bone-marrow tissue (as applicable) from surgery for analysis.",[434,435,436,437,438,439,440,441,29,442,443],"Degenerative Disc Disease","DDD","Degenerative Disc Disease Lumbar","Degenerative Disc Disease, Lumbar","Lumbar Disc Herniation","Disc Herniation, Lumbar","Bone Marrow Aspirate Concentrate","Intervertebral Disc Displacement","Chronic Low Back Pain (CLBP)","CLBP - Chronic Low Back Pain",[445,446,447,448,205],"degenerative disc disease","lumbar disc herniation","bone marrow aspirate concentrate","intervertebral disc displacement",{"date":450,"type":34},"2026-07-29",{"date":452,"type":22},"2026-08-30",{"date":454,"type":22},"2030-12",{"name":456,"class":78},"Weill Medical College of Cornell University",{"id":458,"slug":459,"hasResults":12,"nctId":460,"briefTitle":461,"officialTitle":462,"acronym":4,"eligibilityCriteria":463,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":464,"targetDuration":466,"studyType":467,"phases":4,"briefSummary":468,"conditions":469,"keywords":471,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":478,"lastUpdatePostDateStruct":479,"startDateStruct":480,"completionDateStruct":482,"leadSponsor":484,"locationsCount":79},"100649474","pre-visit-ai-symptom-checking-and-shared-decision-making-in-spine-physical-therapy-100649474","NCT07733752","Pre-Visit AI Symptom-Checking and Shared Decision-Making in Spine Physical Therapy","When AI Is the First Clinician: Impact of Pre-Visit AI Use on Presentation, Diagnostic Expectations, and Shared Decision-Making in Spine Physical Therapy","Inclusion Criteria:\n\n* Age: 18 years or older\n* Presenting for a new evaluation at an outpatient physical therapy clinic for a spine-related musculoskeletal complaint, including Neck, Thoracic, and Low back pain With or without radicular symptoms\n* Able to provide informed consent.\n* Able to read, understand, and complete study questionnaires\n\nExclusion Criteria:\n\n* Recent spinal surgery within the past 3 months, due to differing clinical pathways and management strategies.\n* Presence of serious spinal pathology under active medical management, such as:\n\nMalignancy (e.g., metastatic disease) Spinal infection Acute fracture\n\n* Cognitive impairment or other conditions that limit the ability to provide informed consent or reliably complete study measures.\n* Patients currently enrolled in another study that may influence clinical decision-making or outcomes related to spine care.",{"count":465,"type":22},200,"6 Weeks","OBSERVATIONAL","Artificial intelligence (AI) symptom-checking tools, including large language models such as ChatGPT, are increasingly used by patients before they seek care. These tools may shape patients' beliefs about their diagnosis, how serious they think their condition is, and when they decide to seek treatment. It is not yet known how this pre-visit AI use affects the initial physical therapy encounter for spine-related problems.\n\nThis prospective observational cohort study examines whether prior use of AI symptom-checking tools influences the first physical therapy evaluation in adults presenting with spine-related musculoskeletal complaints (neck, thoracic, or low back pain, with or without radicular symptoms). Consecutive patients attending an outpatient physical therapy clinic for a new evaluation are grouped as AI users or non-AI users based on whether they used such a tool for their current complaint in the previous 30 days.\n\nThe primary outcome is shared decision-making, measured with the SDM-Q-9 immediately after the initial evaluation. Secondary outcomes include stage of presentation, agreement between the patient's expected diagnosis and the clinician's classification, baseline pain and disability, functional performance, and clinical outcomes at 2 and 6 weeks. The investigators hypothesize that prior AI use is associated with differences in shared decision-making and in how patients present for care.",[29,148,470],"Radiculopathy",[472,473,474,475,476,477],"Artificial intelligence","ChatGPT","Shared decision-making","SDM-Q-9","Spine","Patient expectations","2026-07-24",{"date":450,"type":34},{"date":481,"type":34},"2026-06-10",{"date":483,"type":22},"2027-02-10",{"name":485,"class":78},"Assiut University",{"id":487,"slug":488,"hasResults":12,"nctId":489,"briefTitle":490,"officialTitle":490,"acronym":491,"eligibilityCriteria":492,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":493,"targetDuration":4,"studyType":23,"phases":495,"briefSummary":496,"conditions":497,"keywords":499,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":508,"lastUpdatePostDateStruct":509,"startDateStruct":510,"completionDateStruct":511,"leadSponsor":513,"locationsCount":79},"100649215","impact-of-the-receptive-music-intervention-tool-music-care-on-changes-in-the-functional-abilities-of-patients-with-chronic-low-back-pain-100649215","NCT07731204","Impact of the Receptive Music Intervention Tool (MUSIC CARE©) on Changes in the Functional Abilities of Patients With Chronic Low Back Pain","LOMBALZIC'","Inclusion Criteria:\n\n* Diagnosed with chronic low back pain by a Physical Medicine and Rehabilitation (PMR) physician, defined as lumbar pain and\u002For pain radiating to the lower limb that affects daily and professional activities and has lasted more than 3 months\n* If surgery was performed, it must have been done at least 3 months before entering the study\n* Adult (18 years of age or older) admitted to the day hospital at Clinique Saint-Roch for a chronic low back pain rehabilitation program\n* Considered able to return to work, as assessed by the PMR physician during the pre-admission consultation, with no medical contraindication to resuming professional activity\n* Affiliated with a French social security scheme\n* Has given written informed consent to participate in the study\n\nExclusion Criteria:\n\n* Hearing impairment that would prevent the use of the MUSIC CARE© device\n* Medical contraindication to hydrotherapy (balneotherapy)\n* Symptomatic disc herniation\n* Vertebral fracture or history of recent vertebral fracture within the past 2 years\n* Unstable spondylolisthesis\n* Disc-vertebral infection (spondylodiscitis)\n* Inflammatory rheumatic disease such as ankylosing spondylitis (spondyloarthritis) or rheumatoid arthritis\n* Constitutional connective tissue disorder such as Ehlers-Danlos syndrome or Marfan syndrome\n* Severe, unstabilized, or decompensated psychiatric disorder, including psychotic disorders, acute-phase bipolar disorder, or severe major depressive episode\n* Central nervous system neurological disease such as multiple sclerosis, stroke, or Parkinson's disease\n* Peripheral neuropathy of the lower limbs\n* Unstabilized cardiovascular disease\n* Active cancer treatment or cancer diagnosis within the past 2 years\n* Surgery for a reason other than low back pain within the past 6 months\n* Currently retired (not in active employment)\n* Currently enrolled in another interventional research study\n* Persons under legal protection as defined by Articles L.1121-5 to L.1121-8 of the French Public Health Code, including:\n* Persons under guardianship, curatorship, or judicial protection\n* Minors (under 18 years of age)\n* Pregnant or breastfeeding women\n* Any person subject to a legal protection measure or unable to freely provide informed consent",{"count":494,"type":22},34,[53],"Brief Summary The goal of this clinical trial is to learn if MUSIC CARE©, a music-based therapy tool, can improve the physical abilities of people with chronic low back pain (back pain that lasts more than 3 months).\n\nThe main questions it aims to answer are:\n\nDoes MUSIC CARE© help participants better perform their daily activities? Does MUSIC CARE© lower the fear of movement in participants? Does MUSIC CARE© help participants return to work?\n\nWhy this study? Chronic low back pain is a leading cause of disability and absence from work. Physical rehabilitation is the recommended treatment. However, many participants develop a fear of movement. This fear slows down their recovery and limits the benefits of rehabilitation.\n\nMUSIC CARE© is a digital music tool. It uses specially designed music to help participants relax and feel less pain. Researchers believe that using MUSIC CARE© before rehabilitation sessions may help participants move more freely and recover better.\n\nHow does the study work?\n\nResearchers will compare two groups of participants:\n\nGroup 1: follows a standard rehabilitation program with MUSIC CARE© Group 2: follows a standard rehabilitation program without MUSIC CARE© This comparison will show whether MUSIC CARE© brings added benefits.\n\nParticipants will:\n\nTake part in a rehabilitation program for 5 to 6 weeks Use MUSIC CARE© before each therapy session (Group 1 only). Complete questionnaires about their pain, fear of movement, and ability to perform daily activities.\n\nBe followed for 6 months after the program ends, including an assessment of their return to work.\n\nWhat could this study change? If results are positive, this study could confirm that MUSIC CARE© is a useful non-drug tool to support rehabilitation for people with chronic low back pain. It could help bring this approach into standard care programs, with no additional medication.",[29,498,56],"Kinesiophobia (Fear of Movement)",[29,28,500,501,502,503,123,339,504,505,506,507],"Music Therapy","Physical Functional Performance","Kinesiophobia","Fear of Movement","Return to Work","Non-Pharmacological Intervention","Patient Reported Outcome Measures","Functional Capacity","2026-07-23",{"date":388,"type":34},{"date":73,"type":22},{"date":512,"type":22},"2027-12",{"name":514,"class":78},"LNA SANTE",{"id":516,"slug":517,"hasResults":12,"nctId":518,"briefTitle":519,"officialTitle":520,"acronym":4,"eligibilityCriteria":521,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":522,"enrollmentInfo":523,"targetDuration":4,"studyType":23,"phases":525,"briefSummary":526,"conditions":527,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":508,"lastUpdatePostDateStruct":529,"startDateStruct":530,"completionDateStruct":532,"leadSponsor":533,"locationsCount":535},"100485923","neural-mechanisms-of-meditation-for-opioid-treated-chronic-low-back-pain-100485923","NCT05607381","Neural Mechanisms of Meditation for Opioid-Treated Chronic Low Back Pain","Neural Mechanisms of Meditation-Based Interventions for Chronic Low Back Pain","Inclusion Criteria:\n\n1\\) men\u002Fwomen 18-65 years of age; 2) current chronic low back pain classified according to the NIH Pain Consortium task force research standards for chronic low back pain (pain on at least half the days in the past 6 months); usual back pain ≥3 on 0-10 scale with opioid medication; and 4) current use of prescription opioids for ≥3 months.\n\nExclusion Criteria:\n\n1\\) Prior experience with MBSR, MBCT, MORE, or extensive involvement in any standardized meditation training, 2) current cancer diagnosis, 3) suicide intent or attempt in the past 30 days, 4) psychosis or moderate\u002Fsevere non-opioid substance use disorder in past 6 months; 5) persons with any electronic objects or certain metal objects in their head or body that are incompatible with MRI; 6) those who have had an abnormal brain MRI in the past; 7) those unable to lie still on their back for 1 to 1.5 hours; and 8) pregnancy.","65 Years",{"count":524,"type":22},188,[53],"The purpose of this research study is to see how a mindfulness meditation-based intervention affects pain. Specifically, we are interested in understanding the pain-relieving brain mechanisms of mindfulness meditation-based therapy for patients with opioid-treated chronic low back pain.",[29,528],"Opioid Use",{"date":413,"type":34},{"date":531,"type":34},"2022-11-30",{"date":237,"type":22},{"name":534,"class":78},"University of Utah",2,{"id":537,"slug":538,"hasResults":12,"nctId":539,"briefTitle":540,"officialTitle":540,"acronym":4,"eligibilityCriteria":541,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":542,"targetDuration":4,"studyType":467,"phases":4,"briefSummary":544,"conditions":545,"keywords":548,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":554,"lastUpdatePostDateStruct":555,"startDateStruct":556,"completionDateStruct":558,"leadSponsor":560,"locationsCount":79},"100517156","biomechanical-validation-of-the-caregiver-assisted-transfer-technique-instrument-100517156","NCT06013878","Biomechanical Validation of the Caregiver Assisted Transfer Technique Instrument","Inclusion Criteria:\n\nIndividuals who use assistance with transfers and their caregivers will be recruited for this study.\n\nCaregiver participants will be included in the study if they meet the following criteria:\n\n1. routinely provide transfer assistance to an adult with a physical disability\n2. serving as a caregiver for at least 3 months\n3. no formal didactic or structured training on assisted transfer techniques received as part of a professional degree or training program\n\nCare recipient participants will be included in the study if they meet the following criteria:\n\n1. has a physical disability diagnosis for at least one year\n2. requires assistance with transfers\n3. currently receives care from an informal caregiver\n\nExclusion Criteria:\n\nCaregiver participants will be excluded if they:\n\n1\\) have a current or recent history of back, neck, or other type of musculoskeletal injury within the last 6 months that would be exacerbated by performing an assisted transfer\n\nCare recipient participants will be excluded if they:\n\n1. have existing pressure ulcers or a recent history of pressure ulcers within the last 3 months\n2. have any recent upper extremity injuries (within the last 6 months) that could be exacerbated by being transferred",{"count":543,"type":22},160,"As of 2020, 53 million Americans provide unpaid care to an individual with a disability. One commonly performed activity of daily living (ADL) provided by informal caregivers is assisted transfers, which requires moving an individual from one surface to another. Approximately 94% of informal caregivers who assist with ADLs to persons with adult-onset chronic physical disabilities affecting mobility reported musculoskeletal discomfort, with pain and discomfort made worse by performing caregiving activities. Although many informal caregivers assist with transfers, most have never received any formal training in proper manual lifting or mechanical lifting techniques. Improper transfer techniques can be detrimental to not only caregiver health but also to the persons they assist resulting in shoulder injury, bruising and pain from manual lift techniques, hip fractures from falls, and skin tears from shear force that occurs with sliding during transfers. Current standard of care provides limited in-person training of caregivers, as most of the rehabilitation process is client-focused. When training is provided clinicians have no means to objectively evaluate if proper techniques are being performed at discharge or when the caregiver and care recipient return home. For this reason, an outcome measure called the Caregiver Assisted Transfer Technique Instrument (CATT) was developed to provide a quick, objective way to evaluate proper technique of caregivers who provide transfer assistance to individuals with disabilities. The CATT evaluates the caregiver's performance on setup, quality of the task performance, and results. After a formal assessment through stakeholder review involving clinicians, informal caregivers, and individuals with physical disabilities who require transfer assistance, the CATT was expanded to include two versions; one that evaluates manual lift technique (CATT-M) and one that evaluates mechanical lift techniques (CATT-L). However, the CATT must undergo further testing with informal caregivers and the individuals they assist to determine if the CATT is a reliable, valid, and responsive tool for identifying skill deficits in caregivers performing assisted transfers. The purpose of this study is to establish the psychometric properties (reliability, validity, and responsiveness) of the CATT and to evaluate the effects of an individualized training session for participants who have transfer technique deficits as identified by the CATT. The long-term goal of this research is to develop the CATT so that it can be used as an objective indicator of transfer performance as well as guide training and educational interventions for informal caregivers to reduce the risk of musculoskeletal pain and injury associated with assisted transfers.",[546,29,547],"Informal Caregivers","Biomechanics",[549,550,551,552,553],"caregivers","outcome assessment, health care","wheelchairs","physical medicine and rehabilitation","moving and lifting patients","2026-07-21",{"date":508,"type":34},{"date":557,"type":34},"2024-07-24",{"date":559,"type":22},"2027-10-31",{"name":561,"class":562},"VA Office of Research and Development","FED",{"id":564,"slug":565,"hasResults":12,"nctId":566,"briefTitle":567,"officialTitle":568,"acronym":4,"eligibilityCriteria":569,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":570,"targetDuration":4,"studyType":23,"phases":572,"briefSummary":573,"conditions":574,"keywords":575,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":580,"lastUpdatePostDateStruct":581,"startDateStruct":582,"completionDateStruct":584,"leadSponsor":586,"locationsCount":4},"100647806","therapeutic-exercise-and-education-for-low-back-pain-100647806","NCT07713082","Therapeutic Exercise and Education for Low Back Pain","Therapeutic Exercise and Education for Patients With Non-Specific Low Back Pain in Primary Health Care: A Multicenter Clinical Trial","Inclusion criteria:\n\n* Patients with non-specific low back pain, aged 18 years or older.\n* Pain duration of more than six weeks\n* Onset or modification of low back pain with maintenance of positions and\u002For movements\n* Presenting a mild-to-moderate level of disability, as determined by the Oswestry Disability Index (ODI) questionnaire.\n* Presence of limitations or symptoms in at least two range of motion (ROM) or coordination assessment tests, as described in clinical guidelines:\n* Lumbar and\u002For hip range of motion (ROM) measured with inclinometry Prone instability test\n* Presence of aberrant movements:\n\n  * Painful arc with flexion or return from flexion\n  * Instability catch\n  * Gower sign\n  * Reversal of lumbopelvic rhythm\n* Strength and endurance of the abdominal musculature\n* Email access and a device with an internet connection are required.\n* Availability and willingness to participate in all study sessions.\n\nExclusion criteria:\n\n* Presence of acute, nociplastic, radicular, and\u002For referred pain\n* Presence of red flags\n* Previous surgeries in the spine, pelvis, or hip\n* Presence of concomitant cardiovascular, neurological, endocrine, or immune pathologies that prevent physical activity\n* Presence of psychiatric disorders\n* Pregnancy\n* Having received physiotherapy treatment, analgesic blocks, corticosteroid injections, or any other type of intervention within the last three months\n* Changes in lifestyle habits, work conditions, or physical activity levels within the last three months\n* Inability to meet the program's physical or cognitive demands during the eight weeks",{"count":571,"type":22},132,[53],"This study will evaluate a new treatment program for patients with ongoing or long-term low back pain who receive care at primary care physiotherapy units. Participants with subacute or chronic nonspecific low back pain will be randomly divided into three groups for comparison of their progress. The first group will receive an eight-week program of therapeutic exercise and health education, which will be delivered entirely online. The second group will receive the same exercise and education program in face-to-face sessions. The third group will receive standard physiotherapy care. The study will last eight weeks, and researchers will follow up with participants three months later. The project's main goal is to measure changes in participants' daily disability levels. The researchers will also examine other important factors, such as pain intensity, fear of movement, anxiety, depression, quality of life, and overall satisfaction with the care received. Measurements will be taken before the study begins, immediately after the eight-week program ends, and at the three-month follow-up. This trial aims to find more accessible, evidence-based ways to treat back pain, reduce hospital waiting lists, and improve patient well-being by combining digital and in-person care.",[29],[205,576,577,578,579],"therapeutic exercise","pain education","primary health care","randomized controlled trial","2026-07-17",{"date":554,"type":34},{"date":583,"type":22},"2027-03",{"date":585,"type":22},"2028-09",{"name":587,"class":78},"University of Valladolid",{"id":589,"slug":590,"hasResults":12,"nctId":591,"briefTitle":592,"officialTitle":593,"acronym":4,"eligibilityCriteria":594,"healthyVolunteers":360,"sex":18,"minAge":19,"maxAge":87,"enrollmentInfo":595,"targetDuration":596,"studyType":467,"phases":4,"briefSummary":597,"conditions":598,"keywords":603,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":580,"lastUpdatePostDateStruct":608,"startDateStruct":610,"completionDateStruct":612,"leadSponsor":614,"locationsCount":79},"100629433","the-relationship-between-transversus-abdominis-muscle-architecture-and-upper-extremity-function-in-patients-with-chronic-low-back-pain-100629433","NCT07474610","The Relationship Between Transversus Abdominis Muscle Architecture and Upper Extremity Function in Patients With Chronic Low Back Pain","The Relationship Between Transversus Abdominis Muscle Architecture and Upper Extremity Function in Patients With Chronic Low Back Pain: A Comparative Ultrasonographic Study","Inclusion Criteria:\n\n* Being between 18-45 years of age.\n* Having a normal Body Mass Index (BMI) (18.5 - 29.9 kg\u002Fm²).\n* For the painful group, having pain for a minimum of 3 months and a minimum of 3\u002F10 pain at rest or during activity. • Not having received medical treatment for back or shoulder pain in the last 12 months for healthy control examinations.\n\nExclusion Criteria:\n\n* Having neurological diseases.\n* Having a diagnosed pathology and\u002For severe pain in the upper extremity.\n* Being a professional athlete.\n* Being pregnant.\n* Having advanced structural spinal deformities (scoliosis, kyphosis, etc.).\n* Having undergone abdominal surgery (Cesarean section is not included).\n* Having undergone spinal and\u002For lumbar surgery.",{"count":430,"type":22},"1 Day","Core stability is the ability to control the position and movement of the trunk for optimal production, transfer, and control of forces in the upper and lower extremities during functional activities.\n\nStudies have shown that TrA activation is delayed in individuals with low back pain. The relationship between core stability and the lower extremity has been frequently studied in the literature, and according to Kibler's 'Kinetic Chain' theory, loss of proximal stability is known to lead to dysfunction in distal segments; however, the relationship between the upper extremity and core stability is still unclear. The aim of our study is to investigate the upper extremity reach capacity and scapular stability of individuals with low back pain in relation to TrA involvement and to compare them with healthy individuals without low back pain.",[29,599,600,601,602],"Functional Reach","Scapular Dyskinesis","Core Muscles","Ultrasound",[205,604,605,606,607],"functional reach","scapular dyskinesis","core","ultrasound",{"date":609,"type":34},"2026-07-20",{"date":611,"type":34},"2026-04-01",{"date":613,"type":22},"2027-08-31",{"name":615,"class":78},"Ilayda Dilan Isik",{"id":617,"slug":618,"hasResults":12,"nctId":619,"briefTitle":620,"officialTitle":621,"acronym":4,"eligibilityCriteria":622,"healthyVolunteers":12,"sex":18,"minAge":623,"maxAge":275,"enrollmentInfo":624,"targetDuration":4,"studyType":23,"phases":626,"briefSummary":627,"conditions":628,"keywords":629,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":580,"lastUpdatePostDateStruct":633,"startDateStruct":634,"completionDateStruct":636,"leadSponsor":638,"locationsCount":79},"100625740","post-facilitatiion-stretch-and-dry-needling-on-hamstring-tightness-in-chronic-low-back-pain-100625740","NCT07426562","Post Facilitatiion Stretch and Dry Needling on Hamstring Tightness in Chronic Low Back Pain","Comparison of Post Facilitatiion Stretch and Dry Needling on Hamstring Tightness in Chronic Low Back Pain","Inclusion Criteria:\n\n* Diagnosed with chronic non-specific low back pain of more than 12 weeks' duration.\n* Positive Straight Leg Raise (SLR) test or Active Knee Extension Test showing hamstring tightness (\\\u003C80° hip flexion with knee extended).\n\nExclusion Criteria:\n\n* History of spinal surgery, fracture, or neurological deficit.\n* Radiculopathy or red flag signs (tumor, infection, inflammatory disorders).\n* Recent steroid injection therapy for low back pain (within 3 months).\n* Contraindications to dry needling (bleeding disorders, infection at site, needle phobia).\n* Pregnancy.\n* Severe needle phobia (for DN group).","20 Years",{"count":625,"type":22},36,[53],"The aim of this research is to compare the effects of post-facilitation stretch and dry needling on hamstring flexibility, pain, lumbar range of motion, pelvic tilt, and functional status in patients with chronic low back pain. This randomized clinical trial will be conducted at Spine Care Physical Therapy and Rehabilitation Centre (SPRC), Peshawar. The sample size will be 36 participants, who will be randomly divided into two groups: 18 participants in the post-facilitation stretch group and 18 participants in the dry needling group. The study duration will be 3 weeks, with interventions applied three times per week. The sampling technique used will be non-probability purposive sampling, followed by random allocation using the sealed opaque envelope method. Participants aged 20-50 years diagnosed with chronic nonspecific low back pain and having hamstring tightness will be included. Outcome measures used in the study will be Active Knee Extension Test (goniometer) for hamstring flexibility, Numeric Pain Rating Scale (NPRS) for pain, goniometer for lumbar flexion and extension, pelvic inclinometer for pelvic tilt, and Modified Oswestry Disability Index (MODI) for functional disability.",[29],[630,631,632],"Chronic Low Back Pain","Dry Needling","Post Facilitation Stretch",{"date":609,"type":34},{"date":635,"type":34},"2026-02-02",{"date":637,"type":22},"2026-08-31",{"name":420,"class":78},{"id":640,"slug":641,"hasResults":12,"nctId":642,"briefTitle":643,"officialTitle":644,"acronym":4,"eligibilityCriteria":645,"healthyVolunteers":12,"sex":18,"minAge":646,"maxAge":647,"enrollmentInfo":648,"targetDuration":649,"studyType":467,"phases":4,"briefSummary":650,"conditions":651,"keywords":653,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":660,"lastUpdatePostDateStruct":661,"startDateStruct":663,"completionDateStruct":665,"leadSponsor":667,"locationsCount":669},"100634746","safety-and-effectiveness-of-ultrasound-guided-pharmacopuncture-for-spinal-diseases-100634746","NCT07543692","Safety and Effectiveness of Ultrasound-guided Pharmacopuncture for Spinal Diseases","Safety and Effectiveness of Ultrasound-guided Pharmacopuncture for Spinal Diseases: A Multi-center, Registry Study","Inclusion Criteria:\n\n1. Patients diagnosed with spinal diseases (KCD codes M and S).\n2. Patients whose Numeric Rating Scale (NRS) score for the most predominant pain (neck pain with upper limb radiating pain OR low back pain with lower limb radiating pain) caused by spinal diseases is 5 or higher.\n3. Outpatients or inpatients scheduled to utilize an ultrasound scan during pharmacopuncture (the decision to perform ultrasound-guided pharmacopuncture is made according to the clinician's routine medical judgment, not for research purposes).\n4. Patients who voluntarily agree to participate in the clinical study and sign the informed consent form.\n\nExclusion Criteria:\n\n1. Patients who have difficulty completing the written informed consent form.\n2. Women who are pregnant, planning to become pregnant, or breastfeeding.\n3. Patients deemed inappropriate for study participation by the investigator due to severe underlying diseases (e.g., cancer or other malignant neoplasms) that may interfere with treatment effects or result interpretation.\n4. Individuals who are deemed unsuitable for participation in the clinical study by the researcher.","19 Years","69 Years",{"count":51,"type":22},"8 Weeks","This multi-center registry study aims to evaluate the safety and effectiveness of ultrasound-guided pharmacopuncture for patients diagnosed with spinal diseases. A total of 600 patients, aged 19 to under 70 years, will be enrolled across six Korean medicine hospitals. Eligible participants must have a pain Numeric Rating Scale (NRS) of 5 or higher for their most dominant spinal pain, which includes neck pain with upper extremity radiating pain, or low back pain with lower extremity radiating pain. As a non-interventional observational study, it will include patients who are already planned to receive ultrasound-guided pharmacopuncture as part of their routine clinical care. The primary outcome is the change in the most dominant spinal pain intensity measured by the NRS from baseline to 4 weeks. Secondary outcomes include functional disability evaluated using the Neck Disability Index (NDI) or Oswestry Disability Index (ODI), quality of life using the EQ-5D-5L, and patient satisfaction. Safety will be closely monitored by assessing all adverse events at every visit, evaluating their incidence, severity, and causality related to the procedure. Participants will be selected based on strict inclusion and exclusion criteria to ensure safety and consistency. Ethical standards including informed consent, data privacy, and ongoing safety monitoring will be rigorously upheld throughout the study.",[652,148,29,470],"Spinal Disease",[654,655,656,657,658,659],"Pharmacopuncture","Ultrasound-guided","Registry","Observational Study","Korean Medicine","Spinal Pain","2026-07-15",{"date":662,"type":34},"2026-07-16",{"date":664,"type":34},"2026-04-29",{"date":666,"type":22},"2027-12-31",{"name":668,"class":78},"Jaseng Medical Foundation",6,{"id":671,"slug":672,"hasResults":12,"nctId":673,"briefTitle":674,"officialTitle":675,"acronym":4,"eligibilityCriteria":676,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":522,"enrollmentInfo":677,"targetDuration":4,"studyType":23,"phases":679,"briefSummary":680,"conditions":681,"keywords":683,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":685,"lastUpdatePostDateStruct":686,"startDateStruct":688,"completionDateStruct":690,"leadSponsor":692,"locationsCount":79},"100645462","comparison-of-traditional-synchronous-and-asynchronous-telerehabilitation-in-office-workers-with-chronic-nonspecific-low-back-pain-100645462","NCT07700589","Comparison of Traditional, Synchronous, and Asynchronous Telerehabilitation in Office Workers With Chronic Nonspecific Low Back Pain","Comparison of the Effectiveness of Traditional, Synchronous, and Asynchronous Telerehabilitation Approaches in Chronic Nonspecific Low Back Pain in Office Workers","Inclusion Criteria:\n\n* Being an office worker aged between 18 and 65 years.\n* Diagnosed with chronic non-specific low back pain (symptoms persisting for more than 3 months).\n* Volunteering to participate in the study and signing the informed consent form.\n* Having a computer, smartphone, or tablet with a stable internet connection capable of supporting video calls.\n\nExclusion Criteria:\n\n* \\- History of spinal surgery, structural spinal deformities (e.g., severe scoliosis), or specific causes of low back pain (e.g., disc herniation with severe radiculopathy, spinal stenosis, spondylolisthesis).\n* Diagnosis of systemic, rheumatological, neurological, or inflammatory diseases affecting the musculoskeletal system.\n* Serious cardiovascular or pulmonary conditions that contraindicate physical exercise.\n* Currently receiving active physical therapy or regular medical intervention for low back pain elsewhere.\n* Pregnancy.",{"count":678,"type":22},45,[53],"Chronic Nonspecific Low Back Pain (NLBP) is a common condition that occurs without a specific underlying pathology, resulting in muscle tension, pain, and a decreased quality of life. Office workers are particularly at risk due to prolonged sitting, ergonomic errors, and low physical activity. While exercise therapy is a primary approach for management, low adherence rates often limit its effectiveness. Telerehabilitation (remote, technology-supported physiotherapy) stands out for its potential to increase access and support continuity of care.\n\nThis study is a randomized controlled trial that will be conducted with 45 office workers aged 18-65 diagnosed with chronic NLBP. Participants will be randomly assigned to three parallel groups: traditional exercise (brochure-based), synchronous telerehabilitation (live sessions), and asynchronous telerehabilitation (pre-recorded videos). The intervention protocol will be implemented for 8 weeks. Evaluations will be performed before and after the 8-week period using the Visual Analog Scale (VAS) for pain intensity, Oswestry Disability Index (ODI) for functional disability, Short Form-36 (SF-36) for health-related quality of life, and a Patient Satisfaction Questionnaire.\n\nThe aim of this study is to compare the effects of traditional, synchronous, and asynchronous telerehabilitation approaches on pain, disability, quality of life, and satisfaction to determine the most effective management model for office workers with chronic nonspecific low back pain.",[682,29],"Chronic Non-Specific Low Back Pain",[29,684,339],"Telerehabilitation","2026-07-13",{"date":687,"type":34},"2026-07-14",{"date":689,"type":22},"2026-08-01",{"date":691,"type":22},"2026-12-31",{"name":693,"class":78},"Istanbul Aydın University"]