[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"major-adverse-cardiac-event-mace\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:major-adverse-cardiac-event-mace":36},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":37,"overallStatus":45,"whyStopped":4,"lastUpdateSubmitDate":46,"lastUpdatePostDateStruct":47,"startDateStruct":50,"completionDateStruct":52,"leadSponsor":54,"locationsCount":4},"100657838","a-cluster-randomized-controlled-trial-100657838",false,"NCT07845448","A Cluster-Randomized Controlled Trial","AI-Empowered Expert Prescription Intervention for Improving Cardiovascular Prognosis Among Primary-Care Hypertensive Populations: A Cluster-Randomized Controlled Trial","Inclusion Criteria:\n\n* Age ≥ 35 years, regardless of gender.\n* Meet the hypertension diagnostic criteria: untreated office SBP ≥ 140 mmHg and\u002For DBP ≥ 90 mmHg; or treated with office BP ≥ 130\u002F80 mmHg; or with history of coronary heart disease, stroke, heart failure, diabetes, or chronic kidney disease and office BP ≥ 130\u002F80 mmHg regardless of treatment status.\n* Have resided continuously in the township for at least 6 months with no plan for long-term relocation within 3 years.\n* Enrolled in the basic medical insurance system.\n* Willing to participate and provide written informed consent.\n\nExclusion Criteria:\n\n* Pregnant or planning pregnancy within the study period.\n* Diagnosed with malignant tumors or terminal illnesses.\n* Severe mental disorders or cognitive impairment that precludes compliance with intervention and follow-up.\n* Concurrent participation in another hypertension intervention trial.\n* Refusal to cooperate with data collection, follow-up, or intervention procedures.","ALL","35 Years",{"count":19,"type":20},14400,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this study is to learn if an AI-generated personalized health report combined with face-to-face guidance from cardiologists can help rural adults with high blood pressure control their blood pressure better and reduce heart attacks and strokes. It will also assess the safety and practicality of this approach.\n\nThe main questions it aims to answer are:\n\nDoes this intervention increase the proportion of patients who achieve blood pressure below 130\u002F80 mmHg at 18 months? Does it lower the rate of major cardiovascular events (heart attack, stroke, heart failure hospitalisation, or cardiovascular death) over 48 months or longer? Does it improve medication adherence, blood pressure levels, and health knowledge, and is it cost-effective? Researchers will compare three groups of townships: one receiving the full AI-plus-cardiologist intervention, one receiving the same follow-up and education but without the AI report and cardiologist consultation, and one continuing with usual local care.\n\nParticipants will:\n\nAttend regular clinic visits for blood pressure measurements, lab tests, and questionnaires.\n\nIf in the intervention group, receive an AI-generated personalised health report and a face-to-face consultation with a cardiologist, plus home blood pressure monitoring guidance and health education.\n\nBe followed for 48 months or longer to track their blood pressure and any cardiovascular events.\n\nAll medications used are standard, widely approved blood pressure drugs; side effects are mild and manageable, and participants will be closely monitored.\n\nParticipation is voluntary, and all personal data will be kept confidential. The study has ethics approval, and informed consent will be obtained from all participants.",[26,27,28,29,30,31,32,33,34,35,36],"Hypertension","Stroke","Cardiovascular","Coronary Heart Disease","Ischemic Heart Disease","Dyslipidaemia","Diabete Mellitus","Heart Failure","Cardiovascular Mortality","All Cause Mortality","Major Adverse Cardiac Event (MACE)",[38,39,40,41,42,26,43,44],"AI-Powered Health Report","Artificial Intelligence","Digital Chronic Disease Management","Primary Care","Community-Based Hypertension Management","Blood Pressure Control","Rural Cardiovascular Health","NOT_YET_RECRUITING","2026-09-21",{"date":48,"type":49},"2026-09-28","ACTUAL",{"date":51,"type":20},"2026-09-10",{"date":53,"type":20},"2031-09-09",{"name":55,"class":56},"Second Affiliated Hospital of Nanchang University","OTHER"]