[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"mandibular-third-molar\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:mandibular-third-molar":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":5},"100658566","virtual-reality-to-reduce-anxiety-in-adults-having-lower-wisdom-tooth-surgery-100658566",false,"NCT07853014","Virtual Reality to Reduce Anxiety in Adults Having Lower Wisdom Tooth Surgery","Effect of Immersive Virtual Reality on Anxiety During Surgical Removal of Mandibular Third Molars in Adults: A Randomized Controlled Trial","Inclusion Criteria:\n\nAdults aged 18 years or older. Indication for surgical removal of a mandibular third molar. Mandibular third molar with a Pederson difficulty score of 5 or higher on panoramic radiography.\n\nGeneral health status permitting oral surgery, with no current acute infection, swelling or acute pain at the surgical site.\n\nAble and willing to provide written informed consent and comply with the study procedures and scheduled follow-up visits.\n\nExclusion Criteria:\n\nSevere psychiatric disorder, severe dizziness or a history of significant motion sickness that may interfere with use of virtual reality.\n\nSystemic medical conditions that do not permit surgical treatment, including uncontrolled cardiovascular disease, uncontrolled diabetes mellitus or current use of immunosuppressive medication.\n\nPregnancy or breastfeeding. Current or previous radiotherapy involving the maxillofacial region.","ALL","18 Years",{"count":19,"type":20},120,"ESTIMATED","INTERVENTIONAL",[23],"NA","This randomized controlled trial will evaluate whether immersive virtual reality can reduce anxiety in adults undergoing surgical removal of mandibular third molars under local anesthesia. A total of 120 participants will be assigned to either an immersive virtual reality group or a standard-care control group. Participants in the virtual reality group will use a Meta Quest 3 headset displaying relaxing natural scenery beginning 2-3 minutes before local anesthesia and continuing through completion of surgery. Both groups will undergo the same standardized surgical protocol. The primary outcome is state anxiety during surgery, assessed using the State-Trait Anxiety Inventory-State scale (STAI-S). Secondary outcomes include intraoperative pain and immediate postoperative satisfaction. Additional measures will assess postoperative pain, swelling, mouth opening, wound healing, analgesic use, adverse events and acceptability of virtual reality.",[26,27],"Dental Anxiety","Mandibular Third Molar",[29,27,30,31,32,33],"Virtual Reality","Third Molar Surgery","Oral Surgery","State-Trait Anxiety Inventory","Immersive Virtual Reality","RECRUITING","2026-09-25",{"date":37,"type":38},"2026-10-01","ACTUAL",{"date":40,"type":38},"2026-06-09",{"date":42,"type":20},"2027-07-30",{"name":44,"class":45},"Hanoi Medical University","OTHER"]