[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"mastication-disorder\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:mastication-disorder":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100646307","nutritional-intervention-for-older-adults-with-complete-dentures-100646307",false,"NCT07692828","Nutritional Intervention for Older Adults With Complete Dentures","Novel Dietary Guidelines for Elderly Denture-wearers to Ensure Adequate Nutritional Intake, Good Quality of Life and Enhanced Performance on Cognitive Tasks","Inclusion Criteria:\n\n* Men and women aged 60 to 80 years.\n* Systemically healthy individuals or those with controlled chronic systemic conditions under regular medical supervision.\n* Functionally independent individuals, or those with a dedicated family member or caregiver available to provide support throughout the study period.\n* Wearers of both maxillary and mandibular complete removable dentures.\n* Adequate stability, retention, and functionality of both complete dentures allowing the participant to chew effectively during daily meals (accepting minor retention or stability limitations in the mandibular prosthesis, provided routine functional mastication is maintained).\n* Acceptable centric occlusion and jaw relationship allowing functional mastication.\n* Intact oral mucosa without active lesions or severe soreness in the denture-bearing areas.\n\nExclusion Criteria:\n\n* Altered salivary flow (hyposalivation or xerostomia) identified via anamnesis and sialometry, with an unstimulated salivary flow rate \\\u003C 0.1 mL\u002Fmin or a stimulated salivary flow rate \\\u003C 0.5 mL\u002Fmin.\n* Active oral mucosa diseases or lesions (e.g., cheilitis, denture stomatitis, ulcers, or aphthae) verified through intraoral examination.\n* Diagnosis of a major neurocognitive disorder by a qualified professional, verified via medical records and\u002For caregiver interview.\n* Color blindness (daltonism or color vision deficiency).\n* Presence of signs or symptoms of temporomandibular disorders (TMD).\n* Known history of allergy to peanuts or latex.\n* Underweight or severe undernutrition, defined as a Body Mass Index (BMI) \\\u003C 18.5 kg\u002Fm².","ALL","60 Years","80 Years",{"count":20,"type":21},40,"ESTIMATED","INTERVENTIONAL",[24],"NA","The purpose of this clinical trial is to test a nutritional intervention. This study helps older adults who wear complete removable dentures improve their health.\n\nThe main questions the study aims to answer are:\n\n* What are the participants life experiences living with complete dentures before the intervention?\n* Does the intervention improve the diet quality of the participants?\n* Does the intervention improve nutritional status of the participants?\n* Does the intervention improve chewing performance and muscle strength?\n* Does the intervention increase the thickness of the masticatory muscles?\n* Does the intervention improve stress and muscle health markers in saliva?\n* Does the intervention improve cognitive performance and oral health-related quality of life?\n* Does the intervention improve cerebral blood flow? The study will include a total of 40 participants, who will be assigned to two groups. One group of 20 participants will receive the nutritional intervention, while the other group of 20 participants will maintain their usual diet during the study period. This comparison will allow the investigators to assess the effectiveness of the intervention.\n\nParticipants will:\n\n* Take part in a personal interview about their life experience with dentures.\n* Follow a dietary guide with recommendations on specific food textures for six months.\n* Receive personalized nutritional counseling and participate in healthy cooking workshops.\n* Use a custom-built mobile application to access the educational content of the nutritional guide, view instructional videos uploaded biweekly, and receive automated reminder notifications.\n* Attend clinical follow-up assessments, including chewing performance, muscle assessment, saliva markers, assessment of diet quality and nutritional status, cognitive tests, and oral health-related quality of life.\n* Complete these assessments at three main time points: baseline, 3 months, and 6 months.",[27,28,29],"Edentulism Complete","Denture, Complete","Mastication Disorder",[31,32,33,34,35,36],"Nutritional Intervention","Older Adults","Salivary Biomarkers","Cognitive Performance","OHRQoL","Masticatory Performance","NOT_YET_RECRUITING","2026-07-07",{"date":40,"type":41},"2026-07-09","ACTUAL",{"date":40,"type":21},{"date":44,"type":21},"2028-05-12",{"name":46,"class":47},"Universidad de La Frontera","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":16,"minAge":57,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":61,"conditions":62,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":76},"100539049","validation-and-evaluation-of-the-mastication-function-in-adults-the-functional-six-minute-mastication-test-f-6mmt-100539049","NCT06298786","Validation and Evaluation of the Mastication Function in Adults: The Functional Six-minute Mastication Test (F-6MMT).","F-6MMT","Inclusion Criteria:\n\n* Women and men of legal age\n* With or without TMDs symptoms and\n* With or without self-reported jaw fatigue when eating\n\nExclusion Criteria:\n\n* Subjects treated with any type of treatment requiring infiltration of the mandibular region\n* Participants undergoing dental interventions in the last 3 months\n* Individuals missing two or more teeth in the same quadrant.\n* Inability to understand or speak catalan, spanish or english.",true,"18 Years",{"count":59,"type":21},514,"OBSERVATIONAL","Temporomandibular Disorders (TMD) encompass various conditions that affect the temporomandibular joint and associated tissues, often causing or being associated with other symptoms such as jaw pain, myofascial pain, neck pain, and headaches. TMDs are classified according to the DC\u002FTMD instrument in which the joint and pain axes are evaluated. However, there is no evaluation of mandibular function, and TMDs can result in a decrease in jaw strength and resistance. This leads to an increase in the chewing fatigue. Reliable and time-effective diagnostic methods for evaluating masticatory function are crucial in the clinical setting because of the high prevalence of TMD. Chewing efficiency is essential for food preparation and nutrient absorption, and muscle fatigue is a common problem affecting chewing ability. Despite this, there is a lack of validated tests to evaluate chewing fatigue in patients with TMD, which makes its consideration unnoticed in clinical practice.\n\nThe modified six-minute functional chewing test (F-6MMT) was proposed as a tool to evaluate chewing ability and fatigue in patients with TMD. This test is an adaptation of a previously designed test in which subjects with mitochondrial pathology were evaluated; however, the subjects were not instructed to perform functional chewing during the test. In this version, modifications are added so that the test is as functional as possible, allowing chewing to be evaluated in a standardized way, and cut-off points established between healthy subjects and subjects with TMD in terms of chewing capacity in general and fatigue in particular. This study will follow standardized reporting guidelines and recruit participants from diverse clinical settings.",[29,63,64,65,66],"Fatigue","Temporomandibular Disorder","Orofacial Pain","Chewing Problem","2025-05-12",{"date":69,"type":41},"2025-05-15",{"date":71,"type":21},"2025-09",{"date":73,"type":21},"2026-04",{"name":75,"class":47},"Fundació Universitària del Bages",3]