[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"mastication\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:mastication":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,63],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":34,"overallStatus":50,"whyStopped":4,"lastUpdateSubmitDate":51,"lastUpdatePostDateStruct":52,"startDateStruct":55,"completionDateStruct":57,"leadSponsor":59,"locationsCount":62},"100649623","predication-of-arterial-stiffness-in-healthy-adults-by-oral-health-and-chewing-assessments-100649623",false,"NCT07736222","Predication of Arterial Stiffness in Healthy Adults by Oral Health and Chewing Assessments","Oral Structural and Functional Profile as an Additive Biomarker for Explaining Central Arterial Stiffness in the INN.HEALTH Cohort","INNoralHEALTH","Inclusion Criteria:\n\n* adults meeting the INN.HEALTH cohort eligibility criteria, including age ≥18 years, residence in Innsbruck City or Innsbruck-Land, and capacity to consent\n* additionally at Visit 4, participants must report being able to safely chew and, where required, swallow the standardized test materials\n\nExclusion Criteria:\n\n* temporalmandibular joint disorders\n* severe jaw joint complaints\n* active dental treatment at the time of assessment\n* inability to safely chew\u002Fswallow the standardized test materials.",true,"ALL","18 Years",{"count":21,"type":22},750,"ESTIMATED","INTERVENTIONAL",[25],"NA","INN.oral.HEALTH is an sub-study embedded in the Innsbruck Health Promotion Program (INN.HEALTH). The study investigates whether oral health, oral structure, and oral function provide additional information for understanding vascular health in adults from the general population.\n\nCardiovascular and cerebrovascular diseases, such as heart attack and stroke, remain major causes of death and disability. Many risk factors, including blood pressure, blood lipids, blood sugar, smoking, physical activity, sleep, and diet, are already known to influence vascular health. However, oral health may also be related to vascular risk. Conditions such as tooth loss, impaired chewing, reduced tongue strength, or oral disease burden may reflect or contribute to general health and vascular ageing, but their additional value in prevention programs is not yet well understood.\n\nThe main hypothesis of this study is that a standardized oral structure and function profile can improve the explanation of central arterial stiffness beyond established cardiovascular risk factors and lifestyle-related health metrics (INN.HEALTH study). Central arterial stiffness will be assessed using carotid-femoral pulse wave velocity, a marker of vascular ageing and cardiovascular risk.\n\nParticipants will undergo a single oral assessment during Visit 4 of the INN.HEALTH study. The assessment includes screening of oral health status, dentition, bite force, tongue pressure, chewing efficiency, chewing and swallowing performance, questionnaires on oral health-related quality of life and food avoidance, and measurement of masseter muscle thickness. The study does not involve any treatment.\n\nThe results may help clarify whether oral structural and functional markers can contribute to future vascular risk assessment and prevention strategies in the general adult population.",[28,29,30,31,32,33],"Arterial Stiffness","Oral Health","Mastication","Deglutition","Vascular Aging","Cardiovascular Risk",[35,36,37,38,39,40,41,30,42,43,44,45,46,47,48,49],"Carotid-femoral pulse wave velocity","Pulse wave velocity","Central arterial stiffness","Oral health","Bite force","Tongue pressure","Chewing efficiency","Swallowing","Test of Masticating and Swallowing Solids","ToMASS","Food avoidance","Oral health-related quality of life","Masseter muscle thickness","Life's Essential 8","Vascular prevention","RECRUITING","2026-07-27",{"date":53,"type":54},"2026-07-30","ACTUAL",{"date":56,"type":54},"2026-07-08",{"date":58,"type":22},"2027-03-31",{"name":60,"class":61},"VASCage GmbH","OTHER",1,{"id":64,"slug":65,"hasResults":11,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":69,"eligibilityCriteria":70,"healthyVolunteers":11,"sex":18,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":4,"studyType":23,"phases":75,"briefSummary":76,"conditions":77,"keywords":4,"overallStatus":50,"whyStopped":4,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":62},"100502352","orofacial-functions-and-masticatory-function-in-children-with-different-types-of-deterioration-in-oral-health-100502352","NCT05821140","Orofacial Functions and Masticatory Function in Children With Different Types of Deterioration in Oral Health","Evolution of the Maturation of Orofacial Functions and of the Masticatory Function During a Rehabilitation Program, in Children With Different Types of Deterioration in Oral Health","KIDYCROC","Inclusion Criteria:\n\n* All children, from 3 to 17 years old (inclusion limits), attending the special dental care unit of the CHU Estaing in Clermont Ferrand or the CH Guy Thomas in Riom are included in the study:\n* Children and adolescents who have given their consent (6-17 years) and whose legal guardians have given their consent.\n* Children (3-6 years old) with consent from the legal guardian.\n* The subject is affiliated with a Social Security system.\n\nThis may include:\n\n1. children with multiple caries, requiring full rehabilitation under sedation or general anesthesia +\u002F- prosthetic rehabilitation,\n2. children with orofacial dysmorphologies\u002Fmalocclusions, associated or not with a general syndrome, requiring orthodontic and\u002For prosthetic treatment\n3. children with dental abnormalities, associated or not with a general syndrome, requiring conservative, orthodontic and\u002For prosthetic treatment,\n4. children with a healthy oral status in the course of their bi-annual oral health chek-up.\n\nExclusion criteria:\n\n* Children with an ASA III or IV category according to the American Society of Anesthesiologists\n* Children who do not have a solid diet due to severe neuromotor disorders.\n* Children for whom a geographical or organizational barrier prevents follow-up in the service, children in social placement\n* Children over 18 years of age\n* Children (6-17 years) who do not volunteer to participate\n* Children (6-17 years old) who are unable to give consent to participate in the research.\n* Children for whom one of the legal guardians refuses to participate in the study\n* Children whose legal guardians are not capable of giving informed consent.\n* Children who are not affiliated to a Social Security system.\n* Pregnant or nursing teenagers","3 Years","17 Years",{"count":74,"type":22},112,[25],"This project aims at studying the evolution of masticatory function (food bolus granulometry, masticatory behavior, muscle activity and masticatory performance) during oral rehabilitation, in children with different types of oral health impairment.\n\nSecondary objectives are to study the relationships between children masticatory function (food bolus granulometry, masticatory behavior, muscle activity and masticatory performance) and its evolution during oral rehabilitation, and:\n\n* their type of oral health alteration\n* their eating behaviors\n* their height and weight status\n\nDuring examination the following parameters are collected:\n\n* Various clinical indicators of oral health\n* The child's weight and height\n* Frequency and nature of orofacial dysfunctions\n* The oral health related quality of life of children and their families\n* Chewing tests are performed (chewing gum, natural food such as carrot, cereals, and cheese samples, samples of gelatins of different hardness)\n\nExamination and differents tests are performed every six months for a total of 5 years (per participant)\n\nThe dental care procedures performed during the study were carried out in the usual way.",[30,78,79,80],"Disability","Oral Stage","Child Development","2023-04-06",{"date":83,"type":54},"2023-04-20",{"date":85,"type":54},"2022-07-05",{"date":87,"type":22},"2032-02",{"name":89,"class":61},"University Hospital, Clermont-Ferrand"]