[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"mental-wellbeing\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:mental-wellbeing":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,51,79,108,128,149],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100647360","evaluating-practices-that-foster-care-partnerships-and-wellbeing-among-informal-carers-and-long-term-care-workers-100647360",false,"NCT07708649","Evaluating Practices That Foster Care Partnerships and Wellbeing Among Informal Carers and Long-term Care Workers","WELL CARE - Implementation and Evaluation Phase","WELLCARE","Inclusion criteria for recruiting participants will be...\n\nFor informal caregivers:\n\no currently providing - or having provided within the last 6 months - unpaid care or support to a family member, partner, or friend receiving long-term care services;\n\nFor long-term care workers:\n\n* employed in a long-term care setting at one of the participating research sites;\n* directly involved in care provision or implementation of the new practices under study;\n\nFor care recipients:\n\n* currently receiving care from long-term care workers and\u002For informal caregivers;\n* requiring support with everyday personal care and\u002For more complex daily tasks due to ageing, chronic illness, disability or frailty;\n* living in the community or in a long-term care setting included in the study;\n\n  \\- for other stakeholders:\n* involved directly or indirectly in the planning, management, or implementation of the newly adopted practices at the research site;\n\nFor all participants:\n\n* aged 18 years or older;\n* able to provide informed consent;\n* sufficient proficiency in the local language to complete the questionnaire and\u002For participate in an interview;\n\nThe exclusion criteria for recruiting participants will be...\n\n* having a (permanent or temporary) psychiatric disorder or mental illness which makes the person unable to understand instructions and participate in the study activities;\n* experiencing circumstances that would make participation unduly burdensome (e.g., acute stress or illness);\n* providing care for fewer than the minimum number of hours required for inclusion; the threshold will be defined per country in a context-sensitive way, reflecting national differences and the characteristics of the implemented practices and their target populations;\n* only being involved in the provision or receiving of short-term or acute care (i.e., not long-term care);",true,"ALL","18 Years",{"count":21,"type":22},450,"ESTIMATED","INTERVENTIONAL",[25],"NA","WELL CARE aims to strengthen the supports available to informal carers and long-term care (LTC) workers for improving their resilience and mental wellbeing through care partnerships. The project consortium, lead by prof. Elizabeth Hanson (Linnaeus University) and consisting of six research organizations and nine national and European advocacy organizations, identifies good practices able to prevent or mitigate both occupational and non-occupational risks for informal carers' and LTC workers' resilience and mental wellbeing. On this basis, and under its Grant Agreement with the European Commission, the project team develops innovative solution prototypes, which will be transferable across different countries and contexts and guide stakeholders into the actual implementation in 5 European Union (EU) countries (Germany, Italy, Netherlands, Slovenia, Sweden), where the LTC sector presents dissimilar characteristics. Finally, the investigators will exploit the data and evidence collected and generated by WELL CARE to analyze related EU and national policies, and to formulate action-oriented recommendations for policy makers and stakeholders.\n\nThe current study protocol concerns the research activities within Work Package 3 of the project, particularly the activities during the Implementation and Evaluation Phase that runs from September 2026 until the end of 2027. During this phase the project team studies the results of local implementation partners' efforts who - building on the solution prototypes developed earlier in the WELL CARE project - develop and implement new supportive work and care practices. The investigators study the effects that implementing these practices brings about among participating caregivers in terms of mental wellbeing, resilience and care partnership dynamics, while also studying the implementation process itself to capture the processes, conditions and (organizational) contexts favorable to fostering care partnerships.",[28],"Mental Wellbeing",[30,31,32,33,34,35,36,37],"informal carer","caregivers","long-term care worker","mental wellbeing","resilence","partnership","collaboration","professional","NOT_YET_RECRUITING","2026-07-13",{"date":41,"type":42},"2026-07-16","ACTUAL",{"date":44,"type":22},"2027-01-01",{"date":46,"type":22},"2027-09-30",{"name":48,"class":49},"VU University of Amsterdam","OTHER",5,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":59,"targetDuration":4,"studyType":61,"phases":4,"briefSummary":62,"conditions":63,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":78},"100604723","the-microscope-project-100604723","NCT07153224","The MICROSCOPE Project","Mentorship, Intraoperative Consultation, and Coaching for Resilience and Outcomes in Early-career Surgeons Through Collaborative Peer Environment (MICROSCOPE): a Prospective International Time-bound Project","MICROSCOPE","Inclusion Criteria:\n\n* Adult patients (≥18 years) treated for abdominal general surgical conditions in the emergency or elective setting or for thoraco-abdominal traumatic diseases. The list of surgical procedures is reported in the Supplementary Material 1\n* Surgeries performed in elective, trauma, or emergency general surgery care\n\nExclusion Criteria:\n\n* Patients operated by surgeons who completed general surgery residency more than 10 years before the study start date\n* Pediatric patients \\\u003C 18 years of age\n* Patients or surgeons not willing to give their consent to participate",{"count":60,"type":22},340,"OBSERVATIONAL","This multicenter observational prospective study aims to explore the impact of peri-operative support measures (mentorship or coaching or intraoperative consultation) on the mental well-being of early career surgeons. Furthermore sub-analyses will be conducted to explore the impact that surgeons mental wellbeing related to different support measures could have on patients' outcomes",[64,28,65,66,67,68],"Early Career Surgeons","Patients Outcomes","Mentorship","Surgical Coaching","Intra-operative Consultation","2026-04-15",{"date":71,"type":42},"2026-04-17",{"date":73,"type":22},"2026-06-01",{"date":75,"type":22},"2027-12-31",{"name":77,"class":49},"Niguarda Hospital",1,{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":4,"eligibilityCriteria":85,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":86,"targetDuration":4,"studyType":23,"phases":88,"briefSummary":90,"conditions":91,"keywords":92,"overallStatus":98,"whyStopped":4,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":78},"100600829","phase-1-mdma-assisted-therapy-for-mental-healthcare-providers-100600829","NCT07102576","MDMA-Assisted Therapy for Mental Healthcare Providers","A Phase 1, Open-Label Study to Assess Psychological and Biological Effects of MDMA Assisted Therapy When Administered to Mental Health Providers in Training to be MDMA-Assisted Therapists","Inclusion Criteria:\n\n* Are at least 18 years at the time of signing the informed consent.\n* Fluent in English\n* Able to swallow pills\n* Agree to have study visits audiovisually recorded\n* Able to provide a contact (relative, spouse, close friend, or other support person) who is willing and able to be reached by the investigators in the event of the participant becoming unwell or unreachable.\n* Must be licensed, license-eligible, or trainees in a relevant healthcare\u002Fmental health profession\n* Must be learning or have been certified to conduct MDMA-assisted therapy through the Lykos MDMA-Assisted Therapy Training program or authorized affiliate program\n* Body weight of at least 45 kilograms (kg; or 100 pounds (lbs)).\n\nExclusion Criteria\n\n* Have engaged in a new form of psychiatric or mental health care within 12 weeks of enrollment\n* Have a current alcohol or cannabis use disorder of any severity within the 12 months prior to enrollment\n* Have a substance use disorder of any severity within 12 months prior to enrollment\n* Any suicidal ideation within the last 6 months\n* Repetitive or recent use of Ecstasy\u002FMDMA\n* Current enrollment in any other clinical study involving an investigational study treatment or any other type of medical research, unless approved by the study clinician\n* Meet diagnostic criteria for a Major Depressive Episode currently or within the prior 3 months or meet diagnostic criteria for a current anxiety disorder assessed\n* Have a current eating disorder with compensatory behaviors\n* Have a history of, or a current primary psychotic disorder or bipolar disorder\n* Previous participation in a clinical trial that included administration of MDMA\n* Individuals in a personal relationship with the site investigator\n* Are pregnant or nursing or are able to become pregnant and are not practicing an effective means of contraception",{"count":87,"type":22},30,[89],"PHASE1","This is a phase 1, open-label study to assess changes in mental well-being following MDMA administration within a therapeutic setting, in mental health providers who are in training to become MDMA assisted therapists. Secondary outcome measures will examine the effects on provider burnout, provider self-efficacy, mood, self-compassion, quality of life, and other psychological factors. Participants will work with a co-therapy pair as they engage in a preparatory session, one experimental session with MDMA, and an integration session the following day.",[28],[93,94,95,96,97],"Psychedelic Therapy","MDMA","MDMA-Assisted Therapy","Mental Health","Therapist","RECRUITING","2026-03-26",{"date":101,"type":42},"2026-03-27",{"date":103,"type":42},"2026-02-11",{"date":105,"type":22},"2029-12-21",{"name":107,"class":49},"Rachel Yehuda",{"id":109,"slug":110,"hasResults":11,"nctId":111,"briefTitle":112,"officialTitle":112,"acronym":4,"eligibilityCriteria":113,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":114,"targetDuration":4,"studyType":23,"phases":116,"briefSummary":117,"conditions":118,"keywords":4,"overallStatus":98,"whyStopped":4,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":78},"100538160","preliminary-evaluation-of-a-mental-health-program-a-comparison-study-100538160","NCT06287216","Preliminary Evaluation of a Mental Health Program: a Comparison Study","Inclusion Criteria:\n\n* 18 years and above\n* can speak English\n\nExclusion Criteria:\n\n* Have previously participated in the mental hygiene challenge (exclusion for the control group).",{"count":115,"type":22},200,[25],"The mental hygiene challenge is a Royal Ottawa Health Care Group led initiative to engage the staff, clients and community members to attend to their mental well-being by way of practicing mental hygiene activities for 10 min on a daily basis, throughout the month of March. Participants are encouraged to choose one or many of the practices recommended and do them for about 10 minutes a day. Participants are encouraged to make it their own, in that they can combine the practice or tailor them in a way that suits them best. When signing up for the challenge, participants receive free access to a toolkit with brief outlines and instructional videos on various mental hygiene practices.\n\nStudy investigators also encourage participants to divide the 10 minutes in whatever way best works for them, such as 10 minutes all at once, 5 minutes twice, or even 2 minutes five times. This study aims to expand on the work that was done in 2022 and 2023, when the World Health Organization - 5 Wellbeing Index (WHO-5) and the Warwick Edinburgh Mental Wellbeing Scale (WEMWBS) were collected from participants to ascertain the impact of mental hygiene, by way of including a control group.",[28],"2025-12-04",{"date":121,"type":42},"2025-12-12",{"date":123,"type":42},"2024-02-29",{"date":125,"type":22},"2026-04-30",{"name":127,"class":49},"The Royal Ottawa Mental Health Centre",{"id":129,"slug":130,"hasResults":11,"nctId":131,"briefTitle":132,"officialTitle":133,"acronym":4,"eligibilityCriteria":134,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":135,"targetDuration":4,"studyType":23,"phases":137,"briefSummary":138,"conditions":139,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":140,"lastUpdatePostDateStruct":141,"startDateStruct":143,"completionDateStruct":145,"leadSponsor":147,"locationsCount":78},"100601289","brief-mindfulness-workshop-with-or-without-virtual-reality-a-pilot-study-100601289","NCT07108556","Brief Mindfulness Workshop With or Without Virtual Reality: A Pilot Study","Brief Mindfulness Workshop With or Without Virtual Reality: A Randomized Crossover Design","Inclusion Criteria:\n\n* aged 18 years or older\n* reads Chinese\n* understands Cantonese\n\nExclusion Criteria:\n\n* history of sever motion sickness or known intolerance to VR environments\n* impairments that may interfere with the use of VR equipment\n* concurrent or past structured mindfulness training",{"count":136,"type":22},144,[25],"The current study uses a randomized cross-over design, in which participants are exposed to brief mindfulness-based experiential sessions with and without incorporating virtual reality (i.e., the experimental and control conditions, respectively). Order of exposure to these two conditions are counter-balanced and participants are randomized into the two arms of exposure in a different order. Furthermore, this study includes the use of both subjective self-report and objective physiological measures of mental wellbeing. It is hypothesized that VR-incorporated mindfulness-based experiential session brings a greater improvement in state mindfulness, state affect, and stress response. Results shed light on the added value of incorporating VR into brief MBIs, particularly in reference to the typical practice of promoting mindfulness in the local community.",[28],"2025-08-06",{"date":142,"type":42},"2025-08-07",{"date":144,"type":22},"2025-08-02",{"date":146,"type":22},"2025-12-31",{"name":148,"class":49},"The University of Hong Kong",{"id":150,"slug":151,"hasResults":11,"nctId":152,"briefTitle":153,"officialTitle":154,"acronym":4,"eligibilityCriteria":155,"healthyVolunteers":17,"sex":18,"minAge":156,"maxAge":157,"enrollmentInfo":158,"targetDuration":4,"studyType":23,"phases":160,"briefSummary":161,"conditions":162,"keywords":4,"overallStatus":98,"whyStopped":4,"lastUpdateSubmitDate":170,"lastUpdatePostDateStruct":171,"startDateStruct":173,"completionDateStruct":175,"leadSponsor":177,"locationsCount":179},"100548624","rct-the-effectiveness-of-lifehack-in-improving-mental-wellbeing-in-university-students-100548624","NCT06423417","RCT: the Effectiveness of LifeHack in Improving Mental Wellbeing in University Students.","LifeHack: RCT Evaluating the Effectiveness of a Guided E-health Programme in Improving Mental Wellbeing in University Students.","Inclusion Criteria:\n\n* Being fluent in Dutch and\u002For English\n* Being enrolled as a student at one of the 9 participating universities\n* Being 16 years of age or older\n* Having access to a PC or mobile device with internet access\n* Provide informed consent before participation\n* Score of 50 or lower on the MHC-SF. This is 1 SD above the mean baseline score of participants of LifeHack. This inclusion criterion ensures no students with optimal mental wellbeing are included because they will not be able to show any change.","16 Years","99 Years",{"count":159,"type":22},217,[25],"Psychological issues are common among university students and affect mental wellbeing. The Caring Universities (CU) project, involving nine Dutch universities, aims to enhance students' mental health through an annual online questionnaire and a platform offering guided eHealth interventions. One intervention, LifeHack, utilizes cognitive behavioral therapy-based modules to improve mental wellbeing by enhancing resilience and life skills. The effects of LifeHack with pre-post measurements (total n = 216 at post-test) found found that LifeHack led to improvements in mental wellbeing, but dropout rates were influenced by lack of motivation and module relevance. A personalized version of LifeHack is being developed to address these issues and will be evaluated in an RCT to assess its effectiveness in improving mental wellbeing and related outcomes among university students.",[163,164,165,166,167,168,28,169],"Internet-based Intervention","Waiting List Control Group","Depression","Anxiety","Stress","Quality of Life","Resilience","2025-06-17",{"date":172,"type":42},"2025-06-22",{"date":174,"type":42},"2023-11-01",{"date":176,"type":22},"2025-07-31",{"name":178,"class":49},"Universiteit Leiden",2]