[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"methamphetamine-disorders\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:methamphetamine-disorders":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,43,73],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100571533","phase-2-a-single-dose-study-to-evaluate-safety-and-efficacy-of-cs-1103-in-participants-receiving-a-single-dose-of-methamphetamine-100571533",false,"NCT06721494","A Single-Dose Study to Evaluate Safety and Efficacy of CS-1103 in Participants Receiving a Single Dose of Methamphetamine","A Phase 2 Single-Dose Study to Evaluate Safety and Efficacy of CS-1103 in Participants With Methamphetamine Use Disorder Not Seeking Treatment Receiving a Single Dose of Methamphetamine","Major Inclusion Criteria:\n\n1. Healthy participants aged 18 to 55 years, inclusive;\n2. Meets DSM-5 criteria for methamphetamine use disorder;\n3. Not seeking treatment for methamphetamine use disorder;\n4. Primary route of methamphetamine self-administration must be intravenous or smoking;\n5. Able to abstain from methamphetamine without experiencing severe withdrawal;\n6. A body mass index between 18 to 30 kg\u002Fm2, inclusive and a minimum body weight of 56 kg;\n7. Females must not be lactating and must have a negative pregnancy test during screening and admission.\n\nMajor Exclusion Criteria:\n\n1. Estimated glomerular filtration rate \\\u003C60 mL\u002Fmin\u002F1.73 m2;\n2. History of cardiovascular disease;\n3. Current moderate to severe use disorder for alcohol, cannabis, cocaine, opioids, or benzodiazepines;\n4. History of any clinically important disease or disorder which, in the opinion of the Investigator, may interfere with safe study participation.","ALL","18 Years","55 Years",{"count":20,"type":21},40,"ESTIMATED","INTERVENTIONAL",[24],"PHASE2","The purpose of the study is to evaluate the safety, efficacy, and pharmacokinetics of four single, increasing doses of CS-1103, given by intravenous (IV) infusion in otherwise healthy, non-treatment seeking participants with methamphetamine use disorder in the presence of a clinically relevant dose of methamphetamine HCl (30 mg IV).",[27,28,29],"Methamphetamine Intoxication","Methamphetamine Disorders","Methamphetamine Abuse","RECRUITING","2026-07-06",{"date":33,"type":34},"2026-07-07","ACTUAL",{"date":36,"type":34},"2026-02-05",{"date":38,"type":21},"2026-09-11",{"name":40,"class":41},"Clear Scientific, Inc.","INDUSTRY",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":51,"targetDuration":4,"studyType":22,"phases":53,"briefSummary":55,"conditions":56,"keywords":58,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":42},"100565073","prep-readiness-interventions-for-sustained-motivation-prism-100565073","NCT06637436","PrEP Readiness Interventions for Sustained Motivation (PRISM)","Optimizing HIV Prevention for Highly Vulnerable Methamphetamine-using Sexual Minority Men","PRISM","Inclusion Criteria:\n\n* 18 years or older\n* Assigned male a birth\n* Self-reported methamphetamine use in the past 3 months\n* HIV-negative or unknown serostatus at baseline\n* Has not filled a PrEP prescription in the past 6 months\n\nExclusion Criteria:\n\n* Unwilling or unable to provide informed consent",{"count":52,"type":21},400,[54],"NA","This is a hybrid type I randomized controlled trial to test the effectiveness of contingency management (CM) alone versus CM with motivational interviewing (MI) for optimizing entry or re-entry into the HIV prevention or care continua. A total of 400 participants will be randomized to CM (n = 200) or MI+CM (n = 200), all delivered via telehealth. Monthly follow-up assessments will be completed over 12 months to examine effectiveness MI+CM for the primary outcome - filling a pre-exposure prophylaxis (PrEP) or anti-retroviral therapy (ART) prescription (verified using a digital photo). Secondary outcomes will include: self-reported PrEP or ART clinical evaluation by a provider; self-reported meth and other substance use severity (ASSIST), and self-reported receptive and insertive condomless anal sex (CAS).",[57,28],"HIV",[59,60,61,62],"HIV prevention","Methamphetamine","Motivational Interviewing","Contingency Management","2026-05-05",{"date":65,"type":34},"2026-05-07",{"date":67,"type":34},"2025-01-28",{"date":69,"type":21},"2028-04-30",{"name":71,"class":72},"Florida International University","OTHER",{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":80,"sex":16,"minAge":81,"maxAge":82,"enrollmentInfo":83,"targetDuration":4,"studyType":85,"phases":4,"briefSummary":86,"conditions":87,"keywords":88,"overallStatus":95,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":42},"100628686","reliability-validity-and-acceptability-of-a-novel-visual-scale-for-estimating-daily-methamphetamine-use-among-people-who-use-methamphetamine-100628686","NCT07464873","Reliability, Validity, and Acceptability of a Novel Visual Scale for Estimating Daily Methamphetamine Use Among People Who Use Methamphetamine","PROJECT RESIN","Inclusion Criteria:\n\n* Age 20-40 inclusive\n* English speaking\n* Self-reports using methamphetamine at least once in the past 7 days (attempts will be made to enroll participants with varied frequencies of methamphetamine use)\n* At least 1cm of untreated occipital scalp hair\n* Hair is brown or black\n* Willing to provide a hair sample\n\nExclusion Criteria:\n\n* Participant, in the opinion of the investigators, would be unable to complete study procedures",true,"20 Years","40 Years",{"count":84,"type":21},100,"OBSERVATIONAL","PROJECT RESIN: This study is examining the reliability, validity, and acceptability of a novel visual scale for estimating daily methamphetamine use among people who use methamphetamine.",[28],[89,90,91,92,93,94],"methamphetamine","timeline","follow","back","timeline follow-back","resin","NOT_YET_RECRUITING","2026-03-09",{"date":98,"type":34},"2026-03-11",{"date":100,"type":21},"2026-03-15",{"date":102,"type":21},"2026-06-30",{"name":104,"class":105},"Phillip Coffin, MD, MIA","OTHER_GOV"]