[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"metopic-synostosis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:metopic-synostosis":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,51],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":28,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100657239","frontal-reconstruction-without-orbital-advancement-for-moderate-metopic-craniosynostosis-100657239",false,"NCT07837453","Frontal Reconstruction Without Orbital Advancement for Moderate Metopic Craniosynostosis","Frontal Reconstruction Without Orbital Advancement for the Management of Moderate Metopic Craniosynostosis: A Clinical and Morphometric Analysis","Inclusion Criteria:\n\n* Diagnosis of isolated, non-syndromic metopic craniosynostosis.\n* Moderate severity, characterized by frontal angle between 90° and 95°.\n\nExclusion Criteria:\n\n* Syndromic metopic craniosynostosis.\n* Mild and severe degrees of metopic craniosynostosis","ALL",{"count":18,"type":19},15,"ESTIMATED","INTERVENTIONAL",[22],"NA","Metopic craniosynostosis is a condition caused by the early fusion of the metopic suture, leading to restricted frontal bone growth and a triangular head deformity termed trigonocephaly. Conventional surgical treatment typically involves fronto-orbital advancement with a supraorbital bandeau, which can be associated with substantial surgical blood loss and long-term aesthetic deformities such as temporal hollowing.\n\nFor children presenting with moderate metopic craniosynostosis (defined by a frontal angle between 90° and 95°), formal advancement of the orbital rim may not be required. This prospective clinical study aims to assess the efficacy and safety of isolated frontal vault remodelling without supraorbital bandeau advancement. By maintaining the intact orbital rim, this technique aims to achieve structural and aesthetic cranial normalisation while reducing surgical invasiveness and associated complications.",[25,26,27],"Metopic Craniosynostosis","Craniosynostosis","Metopic Synostosis",[29,30,31,32,33,34,35,36,37],"Frontal reconstruction","Cranial vault remodeling","Orbital advancement","Trigonocephaly","Metopic synostosis","Anthropometry","Interfrontal angle","Pediatric neurosurgery","3D CT morphometry","NOT_YET_RECRUITING","2026-09-18",{"date":41,"type":42},"2026-09-23","ACTUAL",{"date":44,"type":19},"2026-10",{"date":46,"type":19},"2029-10",{"name":48,"class":49},"Assiut University","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":59,"enrollmentInfo":60,"targetDuration":4,"studyType":62,"phases":4,"briefSummary":63,"conditions":64,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":50},"100521429","comparing-conservative-to-surgical-treatment-of-trigonocephaly-craniofacial-surgery-in-children-with-trigonocephaly-an-observational-cohort-study-on-clinical-outcomes-psychosocial-wellbeing-and-costs-100521429","NCT06069479","Comparing Conservative to Surgical Treatment of Trigonocephaly Craniofacial Surgery in Children With Trigonocephaly: an Observational Cohort Study on Clinical Outcomes, Psychosocial Wellbeing, and Costs","Comparing Effectiveness of a Conservative Policy to Craniofacial Surgery in Children With Trigonocephaly: an Observational Cohort Study on Clinical Outcomes, Psychosocial Wellbeing, and Costs","Treat Trigono","Inclusion Criteria:\n\n* diagnosis of trigonocephaly\n\nExclusion Criteria:\n\n* metopic ridge (physiologic early closure of metopic suture)","8 Years",{"count":61,"type":19},440,"OBSERVATIONAL","RESEARCH QUESTION Is the effectiveness of conservative policy comparable to that of surgery in children with trigonocephaly, with regard to clinical outcomes and psychosocial functioning, stress for parents, and costs? DESIGN Observational cohort study in children, aged 0 to 8 years old, with trigonocephaly, excluding metopic ridging (physiologic early closure of metopic suture), treated conservatively or surgically.\n\nOUTCOME MEASURES Primary: Head growth decline, indicating raised intracranial pressure Secondary: fundoscopy, cognition, behavior, refraction and vision, forehead shape, quality of life, posttraumatic stress, decisional conflict, costs.",[27],"RECRUITING","2026-09-08",{"date":68,"type":42},"2026-09-11",{"date":70,"type":42},"2022-09-01",{"date":72,"type":19},"2031-08-31",{"name":74,"class":49},"Erasmus Medical Center"]