[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"mhealth\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:mhealth":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,10,0,[8,46,75,97,130,170,202,233,257,291],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100652779","personalized-addiction-treatment-ehancement-100652779",false,"NCT07778394","Personalized Addiction Treatment eHancement","The Vira Platform: A Contextually Triggered Just-in-Time Adaptive Intervention for Opioid Use Disorder","Project Path","Inclusion Criteria:\n\n* Age 22+\n* Current Opioid Use Disorder diagnosis\n* Prescribed buprenorphine or methadone\n* Initiated or reinitiated buprenorphine or methadone treatment recently\n* Access to personal smartphone\n\nExclusion Criteria:\n\n* Not fluent in English\n* Limited mental capacity or inability to provided informed consent","ALL","22 Years",{"count":20,"type":21},40,"ESTIMATED","INTERVENTIONAL",[24],"NA","Many patients stop medication-based treatments for Opioid Use Disorder (OUD) prematurely, placing them at increased risk for overdose and death. Providing targeted interventions for OUD, particularly through an accessible, digital health platform, is a potential way to enhance recovery and keep patients engaged in care. The current study seeks to test whether a digital mental health platform, delivered by peer recovery support specialists to individuals prescribed buprenorphine or methadone medication, will improve treatment outcomes for this high risk population.",[27,28,29],"Opioid Use Disorder","mHealth","Peer Support",[31,32],"Peer Recovery Support","Digital Support","RECRUITING","2026-08-18",{"date":36,"type":37},"2026-08-21","ACTUAL",{"date":39,"type":37},"2026-08-13",{"date":41,"type":21},"2027-03-31",{"name":43,"class":44},"Rhode Island Hospital","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":54,"sex":17,"minAge":55,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":45},"100649761","connecting-loved-ones-to-support-and-empowering-recovery-100649761","NCT07740395","Connecting Loved Ones to Support and Empowering Recovery","Harnessing mHealth to Support Loved Ones of Individuals in Recovery From Substance Use Disorders","Project Closer","Inclusion Criteria for Individuals in Recovery:\n\n* 18+\n* have met criteria for a substance use disorder (with or without concomitant alcohol use disorder) in the past 24 months\n* have taken steps in the past 12 months to quit using drugs, cut down on drug use, or change the way in which they use drugs in order to improve the quality of their lives\n* willing to nominate a loved one to receive KulaMind-Recovery\n* have a loved one who is willing to participate in the study\n* able to understand and speak English and provide written and verbal consent\n\nInclusion Criteria for Loved Ones:\n\n* 18+\n* have a sustained relationship with the individual in recovery and are perceived to be an important person in the individual in recovery's life\n* do not provide professional substance use disorder-related services to the individual in recovery\n* have regular access to a device to engaged with KulaMind-Recovery\n* able to understand and speak English and provide written and verbal informed consent\n* do not endorse current (past month) suicidality",true,"18 Years",{"count":57,"type":21},60,[24],"Substance use disorders are highly prevalent. However, recovery from them is possible. The recovery process can benefit greatly from support from loved ones. Loved ones may need guidance in the most helpful ways to support recovery. This study aims to refine and test a web-based intervention, known as KulaMind-Recovery, which offers online skill building and educational modules, one-on-one video sessions and \"on-demand\" text-based support from a coach, and access to a community forum to connect with others with shared experience.",[61,28],"Substance Use Disorder (SUD)",[63,64,65,66],"Recovery","Loved Ones","Addiction","Substance Use","2026-08-17",{"date":69,"type":37},"2026-08-19",{"date":71,"type":37},"2026-07-17",{"date":73,"type":21},"2027-04-30",{"name":43,"class":44},{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":4,"eligibilityCriteria":81,"healthyVolunteers":54,"sex":17,"minAge":55,"maxAge":4,"enrollmentInfo":82,"targetDuration":4,"studyType":22,"phases":84,"briefSummary":85,"conditions":86,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":45},"100504457","msaada-a-mobile-health-tool-100504457","NCT05848557","mSaada: A Mobile Health Tool","mSaada: A Mobile Health Tool to Improve Cervical Cancer Screening in Western Kenya","R21\n\nAim 1 Community health volunteers (CHVs), facility providers and supervisors, Ministry of Health officials\n\nInclusion Criteria:\n\n* 18 years or older\n* be employed by a government clinic\n* be working in cervical cancer screening\n\nExclusion Criteria:\n\n* Does not understand the study purpose and details\n* Is not willing to provide informed consent\n\nWomen\n\nInclusion Criteria:\n\n\\- between 30 and 65 years old\n\nExclusion Criteria:\n\n* Does not understand the study purpose and details\n* Is not willing to provide informed consent\n\nAim 2 Community health volunteers (CHVs)\n\nInclusion Criteria:\n\n* 18 years or older\n* be employed by a government clinic\n* be working in cervical cancer screening\n\nExclusion Criteria:\n\n* Does not understand the study purpose and details\n* Is not willing to provide informed consent\n\nWomen\n\nInclusion Criteria:\n\n* between 30 and 65 years old\n* intact cervix and uterus\n* able to provide informed consent.\n\nExclusion Criteria:\n\n* Does not understand the study purpose and details\n* Is not willing to provide informed consent\n\nR33\n\nWomen (knowledge and risk perception surveys) We plan to enroll approximately 600 women (50 per health facility) to complete a survey about cervical cancer and HPV knowledge, risk perception and screening awareness, acceptability and self-efficacy.\\\\\n\nEligibility criteria for women participants include:\n\n* Reside within Siaya County, in one of the study communities\n* Eligible for cervical cancer screening per the Kenya Ministry of Health guidelines and\n* Ability to provide informed consent.\n\nCHPs in both arms will be asked to complete a survey about their self-efficacy, knowledge of HPV and cervical cancer, and the usability of the mSaada app (CHPs in the intervention arm only).\n\nInclusion:\n\n* CHV participants must be employed by government clinics in Siaya County, and\n* be able to provide informed consent.\n\nExclusion:\n\n* Does not understand the study purpose and details\n* Is not willing to sign an informed consent",{"count":83,"type":21},6000,[24],"In the R21 phase of this project, investigators will: (1) work with key stakeholders and local and international developers to finalize the mSaada platform, building on the existing prototype to add patient and specimen tracking functionality; and (2) carry out a pilot to identify the patient, provider and health system factors necessary to design a trial to evaluate mSaada effectiveness in assisting community health volunteer-led home-based HPV screening, and implementation factors. Investigators will carry out a six-month pilot of mSaada with community units in two health facilities providing HPV-based screening, and use performance metrics including system usage rates, workflow observations and qualitative data to guide the planning of a to determine effectiveness.\n\nIn the R33 phase of the project, investigators plan to: (1) conduct an 18-month c-RCT across 12 health facilities to determine the impact of mSaada on cervical cancer screening uptake, treatment acquisition and cervical cancer knowledge levels among women in the community; and (2) measure the requisite implementation factors for mSaada effectiveness, sustainability, and scale-up. The rigorous study design will allow us to determine the clinical impact of mSaada, ensure the local and regional infrastructure has the capacity necessary for sustainability and develop strategies for widespread implementation and scale-up. Collaboration with key stakeholders from the Kenya Ministry of Health will facilitate the development of a long-term sustainability plan as the country moves toward HPV-based cervical cancer screening. Investigators anticipate the mSaada platform will play a pivotal role in facilitating the introduction of HPV-based screening programs that can reach women in settings with limited health care infrastructure.",[87,88,28],"Cervical Cancer","HPV","2026-08-11",{"date":39,"type":37},{"date":92,"type":37},"2024-02-19",{"date":94,"type":21},"2027-06-30",{"name":96,"class":44},"Duke University",{"id":98,"slug":99,"hasResults":11,"nctId":100,"briefTitle":101,"officialTitle":102,"acronym":4,"eligibilityCriteria":103,"healthyVolunteers":11,"sex":17,"minAge":104,"maxAge":105,"enrollmentInfo":106,"targetDuration":4,"studyType":22,"phases":108,"briefSummary":109,"conditions":110,"keywords":118,"overallStatus":120,"whyStopped":4,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":122,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":45},"100646888","effectiveness-of-supervised-and-unsupervised-mhealth-based-exercise-interventions-on-clinical-outcomes-in-adults-with-type-2-diabetes-and-obesity-within-a-primary-care-context-100646888","NCT07685080","\"Effectiveness of Supervised and Unsupervised mHealth-based Exercise Interventions on Clinical Outcomes in Adults With Type 2 Diabetes and Obesity Within a Primary Care Context\"","Effectiveness of Supervised and Unsupervised mHealth-based Exercise Interventions on Clinical Outcomes in Adults With Type 2 Diabetes and Obesity Within a Primary Care Context: a Randomized Controlled Trial Protocol","Inclusion Criteria:\n\n* Diagnosed with both type 2 diabetes mellitus and obesity\n* Aged between 30 and 65 years\n* Body Mass Index (BMI) between 30 and 40 kg\u002Fm²\n* Glycated hemoglobin (HbA1c) greater than 6.5% (48 mmol\u002Fmol)\n* Fasting plasma or capillary blood glucose equal to or greater than 126 mg\u002FdL (7.0 mmol\u002FL)\n* Willing and able to provide informed consent to participate in the study\n* Available and willing to commit to a 20-week intervention period\n* Able and willing to use a smartphone and receive text messages\n* Able and willing to use a wearable device (smartwatch) and its associated mobile application\n\nExclusion Criteria:\n\n* Presence of any obesity-related comorbidity requiring clinical referral, including eating disorders, pseudotumor cerebri, sleep apnea, hypoventilation syndrome, or orthopedic problems that limit physical activity\n* Presence of psychiatric or medical conditions that would prevent compliance with the study protocol\n* History of a cardiovascular event (myocardial infarction, stroke, heart failure episode, or revascularization procedure) in the past 6 months\n* Presence of any medical condition that contraindicates participation in the proposed physical activity program\n* Current use of insulin therapy\n* Presence of orthopedic or other physical limitations that may interfere with the ability to exercise safely\n* Currently undergoing treatment for a malignant tumor (other than non-melanoma skin cancer)\n* Currently receiving treatment for, or diagnosed with, an eating disorder\n* Planned bariatric or weight-loss surgery (e.g., liposuction, gastric band, gastric bypass) within the next 5 months\n* Currently pregnant, given birth in the last 6 months, breastfeeding in the last 3 months, or actively planning a pregnancy in the next 5 months\n* Currently enrolled in, or planning to enroll in, a weight loss program during the study period\n* Lost more than 5 kilograms of body weight in the past 3 months","30 Years","65 Years",{"count":107,"type":21},126,[24],"Type 2 diabetes (T2D) and obesity are two of the most common chronic conditions worldwide, and they frequently occur together. Both conditions are closely linked to physical inactivity, which is currently recognized as a major risk factor for a wide range of diseases. Although structured exercise programs have shown benefits for people living with these conditions, maintaining long-term participation remains a significant challenge. The rise of mobile health (mHealth) technologies - such as smartphone apps and wearable devices - offers a promising new way to support people in becoming and staying more physically active.\n\nThis study aims to compare the effects of two different 20-week exercise intervention programs versus standard medical care in adults aged 30 to 65 who have been diagnosed with both T2D and obesity.\n\nParticipants will be randomly assigned to one of three groups:\n\nGroup 1 (Supervised Training): Participants will attend two in-person, supervised exercise sessions per week at a local sports facility, each lasting 60 minutes. Sessions will be led by a qualified trainer and will include strength, flexibility, and functional exercises. Participants will also receive weekly motivational text messages and group health coaching.\n\nGroup 2 (Unsupervised mHealth Training): Participants will follow the same exercise plan independently using a mobile application (ActiVital), which is part of the Andalusian Physical Activity Prescription Plan (PAPEF). They will receive their weekly training schedule through the app and will also receive text messages and group health coaching.\n\nGroup 3 (Control Group): Participants will continue with their usual medical care without any structured exercise program.\n\nAll participants across the three groups will be provided with a Fitbit Charge 6 wearable device to monitor daily physical activity and health indicators.\n\nThe study's central hypothesis is that both structured supervised exercise and app-guided unsupervised exercise will lead to meaningful improvements in clinical indicators - such as blood glucose levels, glycated hemoglobin (HbA1c), blood lipids, and blood pressure - as well as in body composition, physical fitness, sleep quality, and overall quality of life, when compared to standard care alone. It is also hypothesized that the mHealth approach will show particular benefits in terms of adherence, self-management, and scalability.\n\nA total of 126 participants will be recruited through the Primary Care Center of Osuna (Seville, Spain), with measurements taken before and after the 20-week intervention period. The study will help determine which type of exercise program is most effective and feasible for people managing both type 2 diabetes and obesity in a primary care setting.",[111,112,113,114,28,115,116,117],"Diabetes Mellitus, Type 2","Obesity","Insulin Resistance","Sedentary Behaviors","Physical Exercise","Primary Care","Wearable Devices",[111,112,28,119,115],"Wearable","NOT_YET_RECRUITING","2026-07-02",{"date":123,"type":37},"2026-07-06",{"date":125,"type":21},"2026-10-01",{"date":127,"type":21},"2027-04-01",{"name":129,"class":44},"Escuela Universitaria de Osuna",{"id":131,"slug":132,"hasResults":11,"nctId":133,"briefTitle":134,"officialTitle":135,"acronym":136,"eligibilityCriteria":137,"healthyVolunteers":54,"sex":138,"minAge":139,"maxAge":140,"enrollmentInfo":141,"targetDuration":4,"studyType":22,"phases":143,"briefSummary":144,"conditions":145,"keywords":157,"overallStatus":120,"whyStopped":4,"lastUpdateSubmitDate":161,"lastUpdatePostDateStruct":162,"startDateStruct":164,"completionDateStruct":166,"leadSponsor":168,"locationsCount":45},"100628155","effectiveness-of-an-mhealth-innovation-on-the-impact-of-menstrual-complaints-in-adolescents-100628155","NCT07457957","Effectiveness of an mHealth Innovation on the Impact of Menstrual Complaints in Adolescents","The Effectiveness of an mHealth Innovation on the Impact of Menstrual Complaints in Adolescents - A Randomised Controlled Trial","MGA","Inclusion Criteria:\n\n* Dutch, English, Turkish or Moroccan-Arabic speaking\n* Post menarche\n* Access to a smartphone or tablet with iOS or Android operating system\n\nExclusion Criteria:\n\n* Amenorrhea\n* Pregnancy\n* No menstrual bleeding or withdrawel bleeding in the 3 months prior to inclusion.\n* Previously or currently under treatment by a health care provider for menstrual complaints","FEMALE","12 Years","21 Years",{"count":142,"type":21},874,[24],"The aim of this study is to improve menstrual health-related quality of life in adolescents by using a mobile menstrual health tracker. We will perform a randomized controlled trial to evaluate the (cost)-effectiveness of this mHealth intervention.",[146,147,148,149,150,151,152,153,154,28,155,156],"Dysmenorrhea","Heavy Menstrual Bleeding","Menstrual Cramps","Menstrual Bleeding, Heavy","Menstrual Discomfort","Menstrual Cycle Abnormal","Menstrual Disorder","Menstrual Health","Mobile Application","Menstrual Health Intervention","Adolescent",[158,28,159,156,160],"randomized clinical trial","Menstrual health","Menstrual Tracker App","2026-03-04",{"date":163,"type":37},"2026-03-09",{"date":165,"type":21},"2026-02-16",{"date":167,"type":21},"2029-05-31",{"name":169,"class":44},"Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)",{"id":171,"slug":172,"hasResults":11,"nctId":173,"briefTitle":174,"officialTitle":175,"acronym":176,"eligibilityCriteria":177,"healthyVolunteers":54,"sex":17,"minAge":178,"maxAge":179,"enrollmentInfo":180,"targetDuration":4,"studyType":22,"phases":182,"briefSummary":183,"conditions":184,"keywords":188,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":192,"lastUpdatePostDateStruct":193,"startDateStruct":195,"completionDateStruct":197,"leadSponsor":199,"locationsCount":201},"100595081","feasibility-and-efficacy-of-ambulance-based-m-health-for-pediatric-emergencies-feamer-trial-100595081","NCT07027813","Feasibility and Efficacy of Ambulance-Based m-Health for Pediatric Emergencies (FEAMER) Trial","Feasibility and Efficacy of Ambulance-Based m-Health for Pediatric Emergencies in Low Resource Settings (FEAMER) Trial","FEAMER","CHILDREN\n\nInclusion criteria:\n\n* Age 0-14 years\n* Children transported by an SIEHS ambulance with a transport time of ≥20 minutes\n* Children presenting to the ChildLife Emergency Department with a parent\u002F guardian present in the ambulance to consent\n* Children classified as \"Charlie, Delta, Echo\" on the Medical Priority Dispatch System\n\nExclusion Criteria:\n\n• Children transported without an adult parent or guardian\n\nEMERGENCY MEDICAL TECHNICIANS (EMTs)\n\nInclusion Criteria:\n\n• EMTs currently employed by the SIEHS EMS service.\n\nExclusion Criteria:\n\n• EMTs who refuse to participate or consent to the study.\n\nTELEMEDICINE PHYSICIANS (TMPs)\n\nInclusion Criteria:\n\n• TMPs currently employed by the CLF Telemedicine services.\n\nExclusion Criteria:\n\n• TMPs who refuse to participate or consent to the study.","1 Minute","14 Years",{"count":181,"type":21},900,[24],"Investigators hypothesize that in a low-resource setting, linking ambulances that transport acutely ill children to a remote pediatric emergency physician using a simple audio-video device will improve the quality of these children's medical decisions and health outcomes. For this purpose, the investigators will conduct a study in Karachi, Pakistan, where they will collect medical data for ill children at the time of ambulance pickup, hospital drop-off, and during hospital triage. During transport, one group will receive a telemedicine call from a trained physician, while the other group will receive basic paramedic treatment. The investigators will then compare both groups.",[185,28,186,187],"Emergencies","Child Health","Critical Illness",[189,190,191],"Emergency Medical Services","Ambulance","Telemedicine","2026-01-05",{"date":194,"type":37},"2026-01-07",{"date":196,"type":37},"2025-06-04",{"date":198,"type":21},"2026-09-30",{"name":200,"class":44},"Weill Medical College of Cornell University",3,{"id":203,"slug":204,"hasResults":11,"nctId":205,"briefTitle":206,"officialTitle":207,"acronym":208,"eligibilityCriteria":209,"healthyVolunteers":11,"sex":17,"minAge":210,"maxAge":211,"enrollmentInfo":212,"targetDuration":4,"studyType":22,"phases":214,"briefSummary":215,"conditions":216,"keywords":220,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":223,"lastUpdatePostDateStruct":224,"startDateStruct":226,"completionDateStruct":228,"leadSponsor":230,"locationsCount":232},"100432937","a-multicenter-study-for-evaluating-a-digital-support-system-in-childhood-obesity-treatment-100432937","NCT04917601","A Multicenter Study for Evaluating a Digital Support System in Childhood Obesity Treatment","A Randomized Controlled Multicenter Study for Evaluating a Digital Support System in Childhood Obesity Treatment (EurEvira)","EurEvira","Inclusion Criteria:\n\n* Age \\>4.0 and \\\u003C17.0 years of age at inclusion\n* Obesity defined based on the International Obesity Task Force criteria iso-BMI 30 - 40 kg\u002Fm2\n* Willingness to participate in an obesity treatment clinical trial\n* Family ability to communicate in the language of the country of residence e.g. write and read messages in the mobile application\n* Parents having a smart phone and an email address\n\nExclusion Criteria:\n\n* Morbid obesity defined as iso-BMI\\>40kg\u002Fm2 independently of age\n* Endocrine disorders other than well controlled hypothyroidism\n* Metabolic disorders of importance for weight control - to be discussed\n* Treatment for depression and other psychiatric disorders during the last 6 months before inclusion\n* Pharmacological treatment of importance for weight control\n* Hypothalamic or monogenic obesity, e.g. syndromes and Mb Down\n* Severe neuropsychiatric disorders that could affect study compliance\n* Eating disorders requiring therapy during the last six months before inclusion or observed at the inclusion screening.","4 Years","17 Years",{"count":213,"type":21},680,[24],"Evira is a digital support system newly developed for treatment of childhood obesity. Through daily weighings at home using a special scale together with a message function in the Evira application, enabling fast and easy communication with the clinic, parents and the clinicians can easily follow the child's weight development. The purpose of this randomized controlled study is to evaluate the effect of adding Evira to the already locally used life-style treatment of childhood obesity.",[217,218,28,219],"Childhood Obesity","Adolescent Obesity","Personalized Medicine",[221,222],"Obesity treatment","Digital support system","2025-09-30",{"date":225,"type":37},"2025-10-06",{"date":227,"type":37},"2022-05-24",{"date":229,"type":21},"2027-12",{"name":231,"class":44},"Karolinska Institutet",5,{"id":234,"slug":235,"hasResults":11,"nctId":236,"briefTitle":237,"officialTitle":238,"acronym":4,"eligibilityCriteria":239,"healthyVolunteers":11,"sex":17,"minAge":240,"maxAge":4,"enrollmentInfo":241,"targetDuration":4,"studyType":22,"phases":243,"briefSummary":244,"conditions":245,"keywords":4,"overallStatus":120,"whyStopped":4,"lastUpdateSubmitDate":248,"lastUpdatePostDateStruct":249,"startDateStruct":251,"completionDateStruct":253,"leadSponsor":255,"locationsCount":4},"100599847","effect-of-digital-intervention-on-self-management-of-hypertensive-patients-at-high-risk-of-stroke-100599847","NCT07089810","Effect of Digital Intervention on Self-management of Hypertensive Patients at High Risk of Stroke","Digital Intervention Based on BCW Theory Has a High Blood Pressure in High-risk Population of Stroke Study on the Effect of Stress on Self-management Behavior of Patients","Inclusion criteria:\n\n(1) hypertensive patients at high risk of stroke screened in the National Screening and Intervention Project for High-risk Population of Stroke (2) willing to participate Cooperate and sign the informed consent form\n\nExclusion criteria:\n\n(1) TIA and stroke patients (2) severe cognitive impairment (MMSE≤9) and (3) inability to use smartphones (4) Refusal to participate","45 Years",{"count":242,"type":21},120,[24],"Stroke is the second leading cause of death in the world, and the number of stroke patients in China ranks the first in the world. Hypertension is the most important risk factor. Studies have shown that 80% of stroke can be prevented by controlling risk factors. However, the management level of hypertension patients in China is still low, and their self-management ability is insufficient.\n\nDigital health management, such as remote monitoring, AI and mobile health platforms, provides a new way for hypertension prevention and control. Foreign studies have shown that digital interventions can effectively improve patients' self-management behaviors, such as diet, exercise and blood pressure control. Interventions based on wechat, APP and other tools in China have also achieved positive results, but face challenges such as patient acceptance, system adaptation and data continuity.\n\nBased on behavior change wheel (BCW) theory \\*\\* and digital platform, this study formulated personalized intervention programs for hypertension patients in high-risk groups of stroke, and promoted health behavior change from three aspects of \\*\\* ability, motivation and opportunity \\*\\*. By improving disease cognition and strengthening self-management, the incidence of stroke can be ultimately reduced, and a new strategy for hypertension prevention and control in the community can be provided.",[246,247],"Hypertension","Mhealth","2025-07-22",{"date":250,"type":37},"2025-07-28",{"date":252,"type":21},"2025-08-01",{"date":254,"type":21},"2026-01-10",{"name":256,"class":44},"Affiliated Hospital of Nantong University",{"id":258,"slug":259,"hasResults":11,"nctId":260,"briefTitle":261,"officialTitle":261,"acronym":262,"eligibilityCriteria":263,"healthyVolunteers":54,"sex":17,"minAge":55,"maxAge":264,"enrollmentInfo":265,"targetDuration":4,"studyType":22,"phases":267,"briefSummary":269,"conditions":270,"keywords":275,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":282,"lastUpdatePostDateStruct":283,"startDateStruct":285,"completionDateStruct":287,"leadSponsor":289,"locationsCount":45},"100587883","phase-2-cultural-adaptation-of-a-web-based-app-myplan-thailand-to-empower-and-support-friends-and-family-of-intimate-partner-violence-survivors-100587883","NCT06934174","Cultural Adaptation of a Web-Based App (myPlan Thailand) to Empower and Support Friends and Family of Intimate Partner Violence Survivors","IPV","Inclusion Criteria:\n\n* being female or males who have a female friend currently (past 6 months) experiencing IPV\n* Thai speaking\u002Freading\n* At least 18 years old\n* Have access to a safe smart-phone or computer with internet\n* Have safe email address\n* Living in Thailand\n\nExclusion Criteria:\n\n* Cannot speak\u002Freading Thai\n* Less than age 18 years old\n* Cannot access to a safe smartphone or computer with internet\n* Not living in Thailand","60 Years",{"count":266,"type":21},100,[268],"PHASE2","This research will support and empower friends\u002Ffamily (F\u002FF) of intimate partner violence (IPV) survivors in Thailand, where IPV is critical and common, and survivors first and foremost seek help for abuse from their F\u002FF. myPlan app (www.myPlanapp.org) is a free mobile evidence-based intervention app to prevent IPV. The app was first developed in the United States (US) and has been disseminated to high-income countries (e.g., New Zealand, Canada, Australia) and lowincome (Kenya). One new hope for improving survivors' psychological and well-being is adapting and introducing the myPlan app for the concerned friends\u002Ffamily who support survivors in Thailand.\n\nTherefore, the propose of this longitudinal research study, Cultural Adaptation of a Web-Based App (myPlan Thailand) to Empower and Support Friends\u002FFamily of Intimate Partner Violence Survivors in Thailand, will have two consecutive phases with three aims: 1) To tailor the myPlan app content for concerned F\u002FF members of Thai IPV survivors, 2) To integrate the adapted myPlan app content for concerned F\u002FF members of Thai IPV survivors, 3) To test the feasibility and acceptability of the adapted myPlan app with concerned F\u002FF members of Thai IPV survivors. Phase 1 (Year 1-2) will achieve aim 1-2 to tailor the myPlan app with Thai survivors and friends\u002Ffamily. The investigators will review current content and conduct in-depth interviews with survivors and concerned F\u002FF members on social norms associated with IPV, informal support systems and the role\u002Fresponsibility in helping survivors, safety strategies used by concerned F\u002FF members and negative consequences for both survivor and F\u002FF member providing support. Moreover, in phase 1, the adapted content will be pilot tested with concerned F\u002FF members of survivors by using cognitive techniques and theater-testing methodology.\n\nPhase 2 (Year 3-4) will achieve aim 3 to test the feasibility and acceptability of the adapted myPlan app with F\u002FF. The investigators will conduct a two-group RCT design with concerned F\u002FF member randomized to receive a) the myPlan app for F\u002FF member, or b) standard usual-care safety planning information. Primary outcomes for F\u002FF members include change in knowledge and attitudes towards IPV and F\u002FF empowerment to plan and take safety support survivor. Secondary outcomes will examine change in F\u002FF' distress, frustration and consequences for supporting the survivor. This phase will also collect feasibility and acceptability data to informed a planned R01 submission in Year 3 of the study. The K43 application outlines a four-year plan to support a candidate who is a nursing instructor with 15 years of work in diverse projects, settings, and disciplines; which positions her for a successful career as an independent researcher in research field of intimate partner violence. The career development plan provides a sequence of carefully selected training and mentoring experiences, including coursework to increase research capacity, leadership skills, mentored research leading to a R01 proposal, peer reviewed publications, and professional networking, that will catapult this research to the next level of research achievement. The team will be a collaboration between the Boromarajonani College of Nursing Khon Kaen (BCNKK), Khon Kaen One Stop Crisis Center (OSCC), Johns Hopkins University (JHU), Notre Dame of Maryland University (NDM), and Auckland University of Technology (AUT), New Zealand.",[271,272,273,28,274],"Intimate Partner Violence (IPV)","Social Support","Empowerment","Effectiveness",[276,277,278,279,280,281],"Intimate partner violence","Friends\u002FFamily memeber","Safety","Social support","mHealth intervention","Thailand","2025-05-08",{"date":284,"type":37},"2025-05-13",{"date":286,"type":37},"2025-04-17",{"date":288,"type":21},"2026-06",{"name":290,"class":44},"Boromarajonani College of Nursing, Khon Kaen",{"id":292,"slug":293,"hasResults":11,"nctId":294,"briefTitle":295,"officialTitle":296,"acronym":297,"eligibilityCriteria":298,"healthyVolunteers":11,"sex":17,"minAge":299,"maxAge":300,"enrollmentInfo":301,"targetDuration":4,"studyType":22,"phases":302,"briefSummary":303,"conditions":304,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":307,"lastUpdatePostDateStruct":308,"startDateStruct":310,"completionDateStruct":312,"leadSponsor":314,"locationsCount":45},"100553088","spirogym-app-aided-cough-rehabilitation-100553088","NCT06481540","SpiroGym App-Aided Cough Rehabilitation","Effect of the SpiroGym App on Voluntary Cough Strength in Parkinson's Disease","ESApp PD","Inclusion Criteria:\n\n* Diagnosis of Parkinsons disease\n* Stable dopaminergic medication (stable dose for at least 1 month)\n\nExclusion Criteria:\n\n* Other neurological disorders\n* Difficulty complying due to neuropsychological dysfunction (dementia with a score of less - - than 19 on the Montreal Cognitive Assessment)\n* Breathing disorders or diseases\n* Smoking in the past 5 years\n* Uncontrolled hypertension","40 Years","80 Years",{"count":57,"type":21},[24],"The pilot study by Srp et al. (2021) proved that the SpiroGym app was feasible for supporting expiratory muscle strength training (EMST) in Parkinson's disease (PD) patients. Two weeks of intensive EMST coupled with SpiroGym were sufficient to significantly improve the participants' voluntary peak cough flow (PCF). The improvement was quantitatively comparable to the results of other intensive EMST studies with longer durations. When interpreting such rapid improvement, the impact of SpiroGym's visual feedback was considered. It was assumed that visual feedback increased training effort compared to regular training without immediate control. However, comparative studies were required to verify the possible additional effects of visual feedback on voluntary PCF compared to EMST without feedback.",[305,306,28],"Parkinson Disease","Voluntary Peak Cough Strength","2025-01-21",{"date":309,"type":37},"2025-01-23",{"date":311,"type":37},"2024-01-01",{"date":313,"type":21},"2025-05",{"name":315,"class":44},"General University Hospital, Prague"]